Research Topics
Species | Xi Qing SunSummaryAffiliation: Sun Yat-sen University Country: China Publications
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Detail Information
Publications
[Change of cerebral blood flow velocity during 4 d head-down tilt bed rest]Xi Qing Sun
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, The Fourth Military Medical University, Xi an, China
Space Med Med Eng (Beijing) 15:163-6. 2002..This decrease of cerebral blood flow velocity may be partially responsible for the increased risk of orthostatic intolerance...- [Effects of simulated microgravity on cardiovascular function and counter effect of lower body negative pressure]Xi Qing Sun
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, The Fourth Military Medical University, Xi an, China
Space Med Med Eng (Beijing) 15:235-40. 2002..The significance of mathematical model in the study of mechanism of microgravity induced orthostatic intolerance was also discussed. The counter effect of LBNP was emphasized... - [Effects of repeated +Gz exposures on the expression of c-fos protein in rabbit brain]Xi Qing Sun
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi an, China
Space Med Med Eng (Beijing) 15:17-21. 2002..To investigate the effect of repeated +Gz exposures on the expression and distribution of c-fos protein immunoreactivity in rabbit brain... - [Effects of lower body negative pressure in the first and last week during 21 d head-down bed rest on orthostatic tolerance and cardiac function]Xi Qing Sun
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi an, China
Space Med Med Eng (Beijing) 15:84-8. 2002..To investigate the changes of orthostatic tolerance and cardiac function during 21 d head-down tilt (HDT) bed rest and effect of lower body negative pressure (LBNP) in the first and the last weeks in humans... - [Development and application of self-powered short arm human centrifuge]Xi Qing Sun
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, The Fourth Military Medical University, Xi an, China
Space Med Med Eng (Beijing) 16:10-3. 2003..To present the development and application of a self-powered short arm human centrifuge... - Effect of lower body negative pressure on orthostatic tolerance and cardiac function during 21 days head-down tilt bed restXi Qing Sun
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi an, P R China
J Gravit Physiol 10:11-7. 2003.... 
Artificial gravity with ergometric exercise preserves the cardiac, but not cerebrovascular, functions during 4 days of head-down bed restChang Bin Yang
Department of Aerospace Biodynamics, Fourth Military Medical University, Xi an 710032, China
Cytokine 56:648-55. 2011..Hence, a daily 1h alternating +1.0 and +2.0 Gz with 40 W exercise training appear to be an effective countermeasure against cardiac deconditioning...- Effect of lower body negative pressure against orthostatic intolerance induced by 21 days head-down tilt bed restXi Qing Sun
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi an, PR China
Aviat Space Environ Med 73:335-40. 2002..The purpose of the present study was to assess the effects of brief LBNP sessions against orthostatic intolerance during a 21-d head-down tilt (HDT) bed rest... - [Effects of self-generated LBNP training on cardiovascular function and lower body negative pressure (LBNP) tolerance]Chang Bin Yang
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi an, China
Space Med Med Eng (Beijing) 17:192-5. 2004..To explore the changes of cardiac function and lower body negative pressure tolerance after self-generated Lower Body Negative Pressure device training and provide experimental evidences for its appliance... - Effect of lower-body negative pressure on cerebral blood flow velocity during 21 days head-down tilt bed restXi Qing Sun
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi an, PR China
Med Sci Monit 11:CR1-5. 2005..The purpose of this study was to investigate cerebral blood flow (CBF) velocity in humans during 21 days of head-down tilt (HDT) bed rest with and without lower-body negative pressure (LBNP)... - [Effects of low gravity preconditioning on rat learning and memory impairment induced by high gravity exposure]Xin Sheng Cao
Department of Aerospace Biodynamics, Fourth Military Medical University, Xi an 710032, China
Di Yi Jun Yi Da Xue Xue Bao 25:212-5. 2005..To study the protective effects of low gravity preconditioning against learning and memory function impairment induced by high gravity exposure in rats... - Combined short-arm centrifuge and aerobic exercise training improves cardiovascular function and physical working capacity in humansChang Bin Yang
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi an, China
Med Sci Monit 16:CR575-83. 2010..This study sought to investigate whether the combination of short-arm centrifuge and aerobic exercise training have advantages over short-arm centrifuge or aerobic exercise training alone... - Effects of repeated brain ischemia induced by rapid lower body negative pressure on brain water and Na+,K+-ATPase activity in ratsXi Qing Sun
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi an, PR China
Aviat Space Environ Med 73:50-3. 2002..These dynamic models are limited because we currently are unable to obtain accurate measures of membrane ion flux or single cell electrophysiological responses from animals under centrifugation... - Counteracting effect of head-up tilt on increased femoral venous compliance after simulated weightlessness in rabbitsXi Qing Sun
Department of Aeropsace Biodynamics, Fourth Military Medical University, Xi an, China
J Gravit Physiol 11:P105-6. 2004..The purpose of this study was to observe the effect of daily head-up tilt (HUT) on stress-strain relationship of femoral vein during simulated weightlessness in rabbits... - Artificial gravity with ergometric exercise as a countermeasure against cardiovascular deconditioning during 4 days of head-down bed rest in humansYong Chun Wang
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, 17 Chang Le Xi Road, Xi an 710032, China
Eur J Appl Physiol 111:2315-25. 2011..The combination of a 30 min alternating of +1.0 and +2.0 Gz for twice per day of AG with 40 W ergometric exercise may offer a promising countermeasure to short duration simulated microgravity... - Acceleration after-effects on learning and memory in rats: +10 Gz or +6 Gz for 3 minXin Sheng Cao
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, 17 Chang Le Xi Lu, Xi an 710032, China
Neurosci Lett 413:245-8. 2007..Thus, +6 Gz/3 min and +10 Gz/3 min exposures may transiently decrease locomotor activity, impair learning, and induce a deficit in memory retention in rats... 
Effects of simulated microgravity on human umbilical vein endothelial cell angiogenesis and role of the PI3K-Akt-eNOS signal pathwayFei Shi
Department of Aerospace Biodynamics, Fourth Military Medical University, Xi an, Shaanxi, China
PLoS ONE 7:e40365. 2012..In conclusion, the present study indicates that 24 h of exposure to simulated microgravity promote angiogenesis among HUVEC-C and that this process is mediated through the PI3K-Akt-eNOS signal pathway...- Expression of heat shock protein after +Gz exposure and its protective effects on +Gz-induced brain injuryJin sheng Li
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi an
Space Med Med Eng (Beijing) 15:391-6. 2002..The degree of neuron damage after +10 Gz/5 min exposure in pre-exposure groups with repeated +4 Gz/3 min 3-5 times was obviously slight comparing with that of single +10 Gz exposure group... - Hyperbaric oxygen preconditioning reduces ischemia-reperfusion injury by stimulating autophagy in neurocyteYong Chun Wang
Department of Aerospace Biodynamics, Fourth Military Medical University, Xi an 710032, China
Brain Res 1323:149-51. 2010..We hypothesize that autophagy induction is involved in HBO-PC induced neuroprotection on IRI in neurocyte. The hypothesis reveals that autophagy may be a new therapeutic target for cerebral IRI... - Simulated weightlessness aggravates hypergravity-induced impairment of learning and memory and neuronal apoptosis in ratsXi Qing Sun
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, 17 Chang Le Xi Road, Xi an 710032, China
Behav Brain Res 199:197-202. 2009..These findings suggest that simulated weightlessness may exacerbate hypergravity-induced impairment of learning and memory, likely caused by neuronal cell death in rats... - Artificial gravity with ergometric exercise can prevent enhancement of popliteal vein compliance due to 4-day head-down bed restYong Jie Yao
Department of Aerospace Medicine, Fourth Military Medical University, Xi an 710032, China
Eur J Appl Physiol 112:1295-305. 2012.... - The expression of heat shock protein 70 in rat brain after +Gz exposureXi Qing Sun
Department of Aerospace Biodynamics, Fourth Military Medical University, Xi an, China
J Gravit Physiol 9:P23-4. 2002..In +10 GZ group, HSP70 protein was only weakly expressed in pyriform cortex after exposure. Conclusions: +Gz exposures may cause time-dependent HSP70 expression in rat brain... - [Expression and distribution of connexin 43 in myocardium of rats after repeated positive acceleration exposures]Ying Zhou
Key Laboratory of Aerospace Medicine, Ministry of Education, Faculty of Aerospace Medicine, The Fourth Military Medical University, Xi an 710032, China
Sheng Li Xue Bao 60:320-6. 2008..These findings facilitate our understanding of the mechanisms of arrhythmias caused by +Gz and provide new protective measures... - Clinorotation upregulates inducible nitric oxide synthase by inhibiting AP-1 activation in human umbilical vein endothelial cellsYong Chun Wang
Department of Aerospace Biodynamics, Fourth Military Medical University, Xi an, China
J Cell Biochem 107:357-63. 2009..These findings indicate that clinorotation upregulates iNOS in HUVECs by a mechanism dependent on suppression of AP-1, but not NF-kappaB. These results support a key role for AP-1 in the signaling of postflight orthostatic intolerance... - [Weightlessness or weightlessness simulation and vascular remodeling]Yong Yue
Space Med Med Eng (Beijing) 16:152-6. 2003..It is proposed that cardiovascular remodeling might be important in studying the causes of orthostatic intolerance after spaceflight... - [Changes of serum alkaline phosphatase and electrolytes during 21 d head down bed-rest]Yong-jie Yao
Department of Aerospace Medicine, The Fourth Military Medical University, Xi'an, China
Space Med Med Eng (Beijing) 15:178-81. 2002..01). ALP level was higher on d2l than on d-3 (P<0.01). Conclusion. 21 d HDT induced increase of Ca, Cl, ALP, and decline of Mg and P. The changes may reflect the imbalance of metabolism... - [Development of self-generating lower body negative pressure device]Chang-bin Yang
Department of Aerospace Medicine, The Fourth Military Medical University, Xi'an, China
Space Med Med Eng (Beijing) 16:281-3. 2003..It might be used in preventing cardiovascular deconditioning during spaceflight or for anti-G training of pilots... - [Effects of repeated lower g exposures on high-G induced memory and balance changes in rats]Xin-Sheng Cao
Space Med Med Eng (Beijing) 17:16-9. 2004..01). Conclusion: It is suggested that repeated low +Gz exposures could provide protective effect on memory and balance changes induced by high +Gz exposure in rats... - [Effects of combined stress of high +Gz and noise on learning and memory in rats]Ting-song Liu
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi'an, China
Space Med Med Eng (Beijing) 17:20-3. 2004..01) immediately after stress. Conclusion: It is suggested that combined stress of noise and +Gz may impair learning and memory of rats, and +Gz seems to contribute more to the combined effects... - Changes of hippocampus somatostatin and learning ability in rats after +Gz exposureXin-Sheng Cao
Department of Aerospace Biodynamics, Faculty of Aviation and Aerospace, The Fourth Military Medical University, Xi'an Shannxi
Space Med Med Eng (Beijing) 18:79-83. 2005..05 or P<0.01) in +6 Gz and +10 Gz groups as compared with control group. Conclusion: +Gz exposure could impair learning ability of rats, and inhibit expression of SS in hippocampus... - [Influences of repeated lower +Gz exposures on high +Gz exposure induced brain injury in rats]Jin-Sheng Li
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi'an, China
Space Med Med Eng (Beijing) 15:339-42. 2002..Conclusion. The degree of neuron damage was obviously slight at the time of exposure to +10 Gz/5 min again after repeated +4 Gz/3 min 3-5 times. The ischemia tolerance at the time of exposure to +Gz was similar to other brain ischemia... - [Effects of high +Gx during simulated spaceship emergency return on learning and memory in rats]Zhi-peng Xu
Space Med Med Eng (Beijing) 18:1-5. 2005..Conclusion: It is suggested that +15 Gx/180 s and simulated weightlessness may affect the ability of learning and memory of rats. Simulated weightlessness for 7 d can aggravate the effect of +Gx on learning and memory ability in rats... - [Effects of +Gz exposure time on memory and behavior in rats]Ying-bo Wei
Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, The Fourth Military Medical University, Xi'an, China
Space Med Med Eng (Beijing) 16:19-23. 2003.... - Effects of denitrogenation on bubble formation during decompression in rabbitsYong-chun Wang
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi'an
Space Med Med Eng (Beijing) 17:89-92. 2004..01). Conclusion: Denitrogenation by inhalation of 100% oxygen for 60 min and 120 min may reduce the generation of gas bubbles in rabbits when decompressed to an altitude of 11000 m... - [Upright tilt table testing and syncope evaluation]Yong-jie Yao
Department of Aerospace Medicine, The Fourth Military Medical University, Xi'an, China
Space Med Med Eng (Beijing) 15:136-9. 2002..This paper reviewed the value of upright tilt [correction of tile] table test in diagnosing unexplained syncope. The method of experiment, information of it's clinical application and points for attention with test were also introduced... - Modulation of {beta}-adrenoceptor signaling in the hearts of 4-wk simulated weightlessness ratsWen Yin
Department of Emergency, Xijing Hospital, Fourth Military Medical University, Xi an 710032, Shaanxi Province, China
J Appl Physiol 105:569-74. 2008..Above results indicated that impaired function of adenylyl cyclase causes beta-adrenoceptor desensitization, which may be partly responsible for the depression of cardiac function...