Wei Ping Liao

Summary

Affiliation: Sun Yat-sen University
Country: China

Publications

  1. Shi Y, Min F, Zhou D, Qin B, Wang J, Hu F, et al. HLA-A*24:02 as a common risk factor for antiepileptic drug-induced cutaneous adverse reactions. Neurology. 2017;88:2183-2191 pubmed publisher
    ..Pretreatment screening is recommended for people in southern China. ..
  2. He N, Lin Z, Wang J, Wei F, Meng H, Liu X, et al. Evaluating the pathogenic potential of genes with de novo variants in epileptic encephalopathies. Genet Med. 2019;21:17-27 pubmed publisher
    ..Data from epileptic encephalopathy-related genes would be helpful in outlining guidelines for evaluating the pathogenic potential of genes in other genetic disorders. ..
  3. Liao W, Chen L, Yi Y, Sun W, Gao M, Su T, et al. Study of antiepileptic effect of extracts from Acorus tatarinowii Schott. Epilepsia. 2005;46 Suppl 1:21-4 pubmed
    ..The volatile oil is shown to be less effective for PTZ-induced convulsions. Both extracts can prevent convulsions as well as convulsion-related GABAergic neuron damage in the brain in the prolonged PTZ kindling model. ..
  4. Yu L, Liao W, Yi Y, Qiu G. ABCB1 G2677T/A polymorphism is associated with the risk of drug-resistant epilepsy in Asians. Epilepsy Res. 2015;115:100-8 pubmed publisher
    ..93, 95% CI: 0.78-1.09; P=0.362) models. A cumulative meta-analysis showed that these results were robust. In conclusion, our analysis indicates that ABCB1 G2677T/A polymorphism may increase the risk of drug-resistant epilepsy in Asians. ..
  5. He N, Li B, Li Z, Wang J, Liu X, Meng H, et al. Few individuals with Lennox-Gastaut syndrome have autism spectrum disorder: a comparison with Dravet syndrome. J Neurodev Disord. 2018;10:10 pubmed publisher
    ..These findings suggest that the co-morbidity of ASD, ID, and epilepsy may result from multifaceted pathogenic mechanisms. ..
  6. Gao Q, Hua L, Wang J, Fan C, Deng W, Li B, et al. A Point Mutation in SCN1A 5' Genomic Region Decreases the Promoter Activity and Is Associated with Mild Epilepsy and Seizure Aggravation Induced by Antiepileptic Drug. Mol Neurobiol. 2017;54:2428-2434 pubmed publisher
    ..The antiepileptic drug-induced seizure aggravation in this patient suggests clinical attention for mutations or variations in noncoding regions that may affect SCN1A expression. ..
  7. Hong Z, Inoue Y, Liao W, Meng H, Wang X, Wang W, et al. Efficacy and safety of adjunctive lacosamide for the treatment of partial-onset seizures in Chinese and Japanese adults: A randomized, double-blind, placebo-controlled study. Epilepsy Res. 2016;127:267-275 pubmed publisher
    ..Adjunctive lacosamide (200 and 400mg/day) was efficacious in reducing POS frequency in Chinese and Japanese patients with a safety and tolerability profile consistent with the three global pivotal studies. ..
  8. Wang J, Lin Z, Liu L, Xu H, Shi Y, Yi Y, et al. Epilepsy-associated genes. Seizure. 2017;44:11-20 pubmed publisher
    ..We also summarized the epilepsy-associated genes according to their function, with the goal to better characterize the association between genes and epilepsies and to further understand the mechanisms underlying epilepsy. ..
  9. Yu P, Zhou D, Liao W, Wang X, Wang Y, Wang T, et al. An investigation of the characteristics of outpatients with epilepsy and antiepileptic drug utilization in a multicenter cross-sectional study in China. Epilepsy Behav. 2017;69:126-132 pubmed publisher
    ..Findings from this study provide extensive information on clinical characteristics and utilization of AEDs in Chinese patients with epilepsy which may help physicians make well-informed clinical decisions. ..

More Information

Publications11

  1. Wei F, Yan L, Su T, He N, Lin Z, Wang J, et al. Ion Channel Genes and Epilepsy: Functional Alteration, Pathogenic Potential, and Mechanism of Epilepsy. Neurosci Bull. 2017;33:455-477 pubmed publisher
    ..These data suggest that the funotype is an essential consideration in evaluating the pathogenicity of mutations and a distinct funotype or funotype-phenotype correlation helps to define the pathogenic potential of a gene. ..
  2. Wang J, Zhou P, Wang J, Tang B, Su T, Liu X, et al. ARHGEF9 mutations in epileptic encephalopathy/intellectual disability: toward understanding the mechanism underlying phenotypic variation. Neurogenetics. 2018;19:9-16 pubmed publisher
    ..This study highlights the role of molecular alteration in phenotype expression and facilitates evaluation of the pathogenicity of ARHGEF9 mutations in clinical practice. ..