Yi Hong Chen

Summary

Affiliation: Sun Yat-sen University
Country: China

Publications

  1. Chen Y, Yue H, Zhang Z, Yuan F, Bi H, Yuan K, et al. Identification and characterization of a mitochondrial unfolded protein response transcription factor ATFS-1 in Litopenaeus vannamei. Fish Shellfish Immunol. 2016;54:144-52 pubmed publisher
    ..vannamei upon V. alginolyticus or WSSV infection. These results suggested that LvATFS-1 not only rolled in mitochondrial specific stress responding, but also important for L. vannamei immunologic defence. ..
  2. Zhang Z, Yuan K, Yue H, Yuan F, Bi H, Weng S, et al. Identification and functional characterization of an endoplasmic reticulum oxidoreductin 1-α gene in Litopenaeus vannamei. Dev Comp Immunol. 2016;57:10-9 pubmed publisher
    ..These results suggested that LvERO1-α plays a critical role in WSSV-induced apoptosis, which likely occurs through the WSSV-activated PERK-eIF2α pathway. ..
  3. Chen Y, Yuan K, Zhang Z, Yuan F, Weng S, Yue H, et al. Identification and functional characterization of a solute carrier family 15, member 4 gene in Litopenaeus vannamei. Dev Comp Immunol. 2016;57:57-66 pubmed publisher
    ..vannamei hematocytes. These results suggest that LvSLC15A4 participates in L. vannamei innate immunity via the NF-κB pathway and thus may be related to UPR. ..
  4. Yuan F, Chen Y, Zhang Z, Yue H, Bi H, Yuan K, et al. Down-regulation apoptosis signal-regulating kinase 1 gene reduced the Litopenaeus vannamei hemocyte apoptosis in WSSV infection. Fish Shellfish Immunol. 2016;50:109-16 pubmed publisher
    ..vannamei. These results suggested that down-regulation of LvASK1 decreased the apoptotic rate of hemocytes in WSSV-infected shrimp, and that it could contribute to the reduction of cumulative mortality in WSSV-infected L. vannamei. ..
  5. Yuan K, Yuan F, Weng S, He J, Chen Y. Identification and functional characterization of a novel Spätzle gene in Litopenaeus vannamei. Dev Comp Immunol. 2017;68:46-57 pubmed publisher
    ..vannamei X-Box binding protein 1 and activating transcription factor 4 in S2 cells. These results suggested that LvSpz4 was involved in L. vannamei innate immunity and caused the crosstalk between the TLR-NF-κB pathway and UPR. ..
  6. Yuan K, Yuan F, He H, Bi H, Weng S, He J, et al. Heat shock 70 kDa protein cognate 5 involved in WSSV toleration of Litopenaeus vannamei. Dev Comp Immunol. 2017;72:9-20 pubmed publisher
    ..vannamei. Therefore, collecting results suggested that LvHSC70-5 should be involved in WSSV toleration of shrimp L. vannamei. ..
  7. Yuan K, He H, Zhang C, Li X, Weng S, He J, et al. Litopenaeus vannamei activating transcription factor 6 alpha gene involvement in ER-stress response and white spot symptom virus infection. Fish Shellfish Immunol. 2017;70:129-139 pubmed publisher
    ..All of these evidences suggested that the ATF6 pathway is a member of the L. vannamei UPR, and it is also engaged in WSSV infection. ..
  8. He H, Chi Y, Yuan K, Li X, Weng S, He J, et al. Functional characterization of a reactive oxygen species modulator 1 gene in Litopenaeus vannamei. Fish Shellfish Immunol. 2017;70:270-279 pubmed publisher
    ..The findings of present study suggest that LvROMO1 plays an important role in ROS production in L. vannamei and is involved in innate immunity. ..