Research Topics
Genomes and Genes
| Sun Yat-sen UniversitySummaryOrganization: Sun Yat-sen University Country: China Top Publications
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Publications
[To carry out studies on treatment of hereditary retinal diseases with gene therapy in China]Wen Sheng Li
Eye Hospital, Wenzhou Medical College, Wenzhou 325027, China
Zhonghua Yan Ke Za Zhi 46:103-5. 2010....
[The cloning of human augmentor of liver regeneration-interacting proteins]Ming hua Tong
Center of Infectious Diseases, The 458th Hospital of PLA, Guangzhou 510602, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:7-10. 2004..To screen human augmentor of liver regeneration(hALR)-interacting proteins and to explore the mechanisms of hALR in liver regeneration...
[Using of evidence-based ophthalmology is imperative in China]Wen-sheng Li
Zhonghua Yan Ke Za Zhi 40:75-7. 2004
[Height structures of dominant species of different subtropical evergreen broadleaved forest communities in Wanmulin Natural Reserve]Xiaoli Bi
Institute of Ecology, Beijing Normal University, Beijing 100875, China
Ying Yong Sheng Tai Xue Bao 14:2355-8. 2003..The results could give a useful clue for the studies on endangered mechanism of rare species...
Potential utility of various protease inhibitors for improving the intestinal absorption of insulin in ratsHui Liu
Department of Pharmacy, Wuhan General Hospital, PO Box 430070, 627 Wu luo Road, Wuhan, China
J Pharm Pharmacol 55:1523-9. 2003..These results suggest that protease inhibitors could increase the insulin efficacy more effectively in the large intestine than in the small intestine...
New atom-type-based AI topological indices: application to QSPR studies of aldehydes and ketonesBiye Ren
Research Institute of Materials Science, South China University of Technology, Guangzhou 510640, PR China
J Comput Aided Mol Des 17:607-20. 2003..The final models are validated to be statistically reliable using the leave-one-out cross-validation and/or an external test set...
[Comparison of the clonal expansion of TCR Vbeta T cells in patients with acute promyelocytic leukemia in vivo and in vitro]Li jian Yang
Institute of Hematology, Jinan University Medical College, Guangzhou 510632, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 11:499-502. 2003..The continual clonal expansion of TCR Vbeta subfamily T cells at different time points after T cells culture could be a specific immune response of patients T cells related to the specific APL cell associated antigen...
A study on additional early physiotherapy after stroke and factors affecting functional recoveryYannan Fang
Department of Neurology, First Affiliated Hospital of Sun Yat sen University, Guangzhou, People s Republic of China
Clin Rehabil 17:608-17. 2003..To investigate whether additional early physiotherapy after stroke improved functional recovery in stroke patients...
[Studies on application of APAGE in male sterile wheat with alloplamic cytoplasm]Xiao Li Wang
Key Laboratory of Crop Heterosis Study and Application of Shaanxi Province, College of Agronomy, Northwest Sci Tech University of Agriculture and Forestry, Yangling 712100, China
Yi Chuan Xue Bao 30:465-8. 2003..ventricosa cytoplasm had the same fertility, but the male sterile wheat with Ae. bicornis cytoplasm could produce male sterile. Meantime, the paper discussed application of APAGE technology in breeding of non-1BL/1RS male sterile wheat...
[Mental stress and crisis intervention in the patients with SARS and the people related]Zhong Cong
Institute of Mental Health, Peking University, Beijing 100083, China
Beijing Da Xue Xue Bao 35:47-50. 2003....
[Evaluation of fetal DNA in maternal plasma for prenatal diagnosis]Yin Zhao
the Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022 PR China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20:360-2. 2003..To explore the application of fetal DNA in maternal plasma for uninvasive prenatal diagnosis...
Dipole localization in surgical treatment of epileptic foci secondary to intracranial mass lesions: retrospective analysis of 47 casesZhi liang Liu
Institute of Neuroscience of PLA, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China
Di Yi Jun Yi Da Xue Xue Bao 23:668-70. 2003..To assess the value of dipole localization in the surgical treatment of epileptic foci arising from intracranial mass lesions and observe the long-term effect of this technique...
[Study on the biology of adults parasite of Cordyceps sinensis, Hepialus biruensis]Shi Jiang Chen
Chongqing Academy of the Materia Medicine, Chongqing 400065, China
Zhongguo Zhong Yao Za Zhi 27:893-5. 2002..To supply the basis of the breeding the host of parasite of Cordyceps sinensis for it's natural culturing, by studying the biology of the host of parasite of C. sinensis, Hepialus biruensis...
[Traumatic optic neuropathy: importance and result of surgical treatment]Yuan Li
Department of Otorhinolaryngology Head and Neck Surgery, Third Affiliated Hospital, Sun Yat Sen University, Guangzhou 510630, China
Zhonghua Er Bi Yan Hou Ke Za Zhi 37:206-9. 2002..To explore the importance and result of surgical treatment in traumatic optic neuropathy (TON)...
[In vitro cleavage activity of the ribozymes constructed specifically for the second exons of pro alpha I and III collagen genes]Jia yuan Zhu
Department of Burns, First Affiliated Hospital, Sun Yat Sen University, Guangzhou 510080, China
Di Yi Jun Yi Da Xue Xue Bao 24:653-5. 2004....
Inhibitory effect of retroviral vector containing anti-sense Smad4 gene on Ito cell line, LI90Xin Bao Xu
Hepatobiliary Surgery Center, People s Hospital, Beijing University, Beijing 100044, China
Chin Med J (Engl) 117:1170-7. 2004..Smad4 is a key intracellular mediator for the transforming growth factor-beta (TGF-beta) superfamily of growth factors. The aim of this study was to assess the effects of the antisense Smad4 gene on Ito cell line, LI90...
[Studies on bilingual teaching of genetics]Jin Ping Liu
South China Unversity of Tropical Agriculture, Agromy College, Danzhou, Hainan 571737, China
Yi Chuan 26:87-8. 2004..Bilingual teaching of genetics is a new teaching research area. This paper introduces a number of texts of genetics in English, and outlines principles of bilingual teaching of genetics...
Differentiation of E14 mouse embryonic stem cells into thyrocytes in vitroNingyi Jiang
Department of Nuclear Medicine, The Second Affiliated Hospital of Sun Yat sen University, Guangzhou, China
Thyroid 20:77-84. 2010..We developed a novel culture method capable of differentiating mouse embryonic stem (ES) cells into thyroid follicular cells...
[Living-related kidney transplantation: report of 175 cases]Su Xiong Deng
Organ Transplantation Center, First Affiliated Hospital of Sun Yat sen University, Guangzhou, China
Nan Fang Yi Ke Da Xue Xue Bao 29:1878-81. 2009..To analyze the clinical characteristics of living-related kidney transplantation (LRKT)...
Risk of cerebral metastases for postoperative locally advanced non-small-cell lung cancerSi Yu Wang
Cancer Center of Sun Yat Sen University, Guangzhou, PR China
Lung Cancer 64:238-43. 2009..Our study assessed the risk factors of brain metastases in patients with postoperative, locally advanced NSCLC. Implications for PCI treatment are discussed...
[Reconstruction of a digital three-dimensional model of the rectum and the surrounding structures based on CT angiographic data]Jin Long Yu
Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China
Nan Fang Yi Ke Da Xue Xue Bao 28:1466-8. 2008..To reconstruct a digital three-dimensional model of the rectum and the surrounding structures based on CT angiographic (CTA) data...
Segmental bone tissue engineering by seeding osteoblast precursor cells into titanium mesh-coral composite scaffoldsF Chen
Xi da RegeMed Lab of Tissue Engineering, Faculty of Life Science, Northwest University, Xi an 710069, PR China
Int J Oral Maxillofac Surg 36:822-7. 2007..In conclusion, a titanium mesh-coral composite scaffold with osteoblast precursor cells is an efficient means to engineer segmental bone, possessing the desired shape and mechanical strength...
Cardiovascular protection of nonmitogenic human acidic fibroblast growth factor from oxidative damage in vitro and in vivoXiao Kun Li
Research Institute for Diabetic Complications, School of Pharmaceutical Sciences, Wenzhou Medical College, Wenzhou, PR China
Cardiovasc Pathol 16:85-91. 2007....
Diagnosis and treatment of small intestinal bleeding: retrospective analysis of 76 casesMing Chen Ba
Department of General Surgery, Nanfang Hospital, Nanfang Medical University, Guangzhou 510515, Guangdong Province, China
World J Gastroenterol 12:7371-4. 2006..To investigate the causes of small intestinal bleeding as well as its diagnosis and therapeutic approaches...
[Effects of matrix metalloproteinase-3, osteopontin, and tissue inhibitor of metalloproteinase-1 in the formation of cataract]Qian Tan
Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008, China
Zhong Nan Da Xue Xue Bao Yi Xue Ban 31:737-41. 2006..To investigate the expression and significance of matrix metalloproteinase-3 (MMP-3), osteopontin (OPN) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in human lens epithelial cells (LECs) of cataract...
Cell survival curve for primary hepatic carcinoma cells and relationship between SF(2) of hepatic carcinoma cells and radiosensitivityZhi zhong Liu
Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
World J Gastroenterol 11:7040-3. 2005..To establish the cell survival curve for primary hepatic carcinoma cells and to study the relationship between SF(2) of primary hepatic carcinoma cells and radiosensitivity...
[Data reconstruction algorithm on echo-planar magnetic resonance spectroscopic imaging]Min Huang
Institute of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, China
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 22:658-62. 2005..For the phase-encoding dimension (ky), the Fourier transform can be readily done with FFT since the data are evenly spaced...
[Antitumor effects of ring-closed and ring-opened hydroxycamptothecin on oral squamous carcinoma cell line Tca8113]An Xun Wang
Department of Stomatology, The First Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong, P R China
Ai Zheng 24:970-4. 2005..This study was to compare the antitumor effects of C-HCPT and O-HCPT on oral squamous carcinoma cell line Tca8113, and explore the mechanisms...
[Expression, purification and serological reactivity of a chimeric antigen of GRA6 with P30 from Toxoplasma gondii]Yue Xi Li
East China Institute of Medical Biotechniques, Nanjing 210002
Sheng Wu Gong Cheng Xue Bao 19:674-9. 2003..The expressed chimeric protein could be used for epidemic investigation of Toxoplasma gondii, blood donor screening, especially for detection of pregnant women, and is of great significance in prevention of Toxoplasma gondii infection...
[Effects of low gravity preconditioning on rat learning and memory impairment induced by high gravity exposure]Xin Sheng Cao
Department of Aerospace Biodynamics, Fourth Military Medical University, Xi an 710032, China
Di Yi Jun Yi Da Xue Xue Bao 25:212-5. 2005..To study the protective effects of low gravity preconditioning against learning and memory function impairment induced by high gravity exposure in rats...
[New improved approaches for DYS385 detection]Shuang bo Tang
Faculity of Forensic Medicine, Sun Yat Sen University, Guangzhou 510089
Fa Yi Xue Za Zhi 19:27-9. 2003..To establish more sensitive methods for detection of DYS385 in routine forensic casework...
[Analysis of terpineol and improvement of technology process in terpineol production]Ming Liang
Fujian Entry Exit Inspection and Quarantine Bureau of PRC, Fuzhou 350001, China
Se Pu 20:577-81. 2002..The contents of beta-terpineol and gamma-terpineol were not so high as in synthetic terpineol...
[Effects of lower body negative pressure in the first and last week during 21 d head-down bed rest on orthostatic tolerance and cardiac function]Xi Qing Sun
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi an, China
Space Med Med Eng (Beijing) 15:84-8. 2002..To investigate the changes of orthostatic tolerance and cardiac function during 21 d head-down tilt (HDT) bed rest and effect of lower body negative pressure (LBNP) in the first and the last weeks in humans...
[Effects of simulated weightlessness on the expression of cyclooxygenase-2 in rat calvarial osteoblasts induced by fluid shear stress]Shu Zhang
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi an, China
Space Med Med Eng (Beijing) 15:27-31. 2002..To investigate the effect of simulated weightlessness on mechanotransduction in rat calvarial osteoblasts...
[Effects of repeated +Gz exposures on the expression of c-fos protein in rabbit brain]Xi Qing Sun
Department of Aerospace Biodynamics, The Fourth Military Medical University, Xi an, China
Space Med Med Eng (Beijing) 15:17-21. 2002..To investigate the effect of repeated +Gz exposures on the expression and distribution of c-fos protein immunoreactivity in rabbit brain...
[Urea soluble fraction of bovine melanin associated antigen and experimental study on its uveitogenic activity]Zongyin Gao
Zhongshan Ophthalmic Center, San Yat sen University, Guangzhou 510060, China Email
Zhonghua Yan Ke Za Zhi 38:168-71. 2002..The purpose of this study was to investigate the uveitogenic activity of autoantigen in the bovine iris-ciliary body...
Expression of vascular endothelial growth factor and its role in oncogenesis of human gastric carcinomaD H Liu
Institute of Combined Injury, Third Military Medical University, Chongqing 400038, China
World J Gastroenterol 7:500-5. 2001..To establish the role of vascular endothelial growth factor (VEGF) in the oncogenesis of human gastric carcinoma more directly...
Stable clonal expansion of the T-cell receptor V beta 6, V beta 17 and V beta 19 T cells in a cGVHD case using genescan analysisY Li
Department of Hematology, Medical College, Jinan University, Guangzhou 510632, China
Chin Med J (Engl) 114:489-92. 2001..To investigate the distribution and clonality of the T-cell receptor (TCR) V beta repertoire in chronic graft versus host disease (cGVHD)...
[Microsatellite polymorphisms at the TNF locus in Hubei Han population]B Fei
Gastroenterology Department, Zhejiang Provincial People s Hospital, Hangzhou, Zhejiang, 310014 P R China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 18:467-71. 2001..To investigate the distribution of tumor necrosis factor(TNF) microsatellite polymorphisms in Chinese...
Vascular endothelial growth factors and liver diseasesB Shi
Department of General Surgery, Shandong Provincial Hospital 324, Jingwu Road, Jinan 250021, P R China
Hepatogastroenterology 48:1145-8. 2001..Further study should be performed in the future in antitumor research and its significance in the process of liver cirrhosis...
Investigation on a novel core-coated microspheres protein delivery systemS Zhou
Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, PR China
J Control Release 75:27-36. 2001..The core-coated microspheres system may have potential use as a carrier for drugs that are poorly absorbed after oral administration...
Severe hepatitis treated with an artificial liver support systemL Lanjuan
Department of Infectious Disease, 1st Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
Int J Artif Organs 24:297-303. 2001..Thus, we concluded that ALSS is a reliable therapy for advanced liver diseases and treatment in early or middle stages is appropriate...
Effects of dihydroartemisinin on fine structure of erythrocytic stages of Plasmodium berghei ANKA strainP Q Chen
Tropical Medicine Institute, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China
Acta Pharmacol Sin 21:234-8. 2000..The fine structural changes of Plasmodium berghei ANKA strain after treatment with the dihydroartemisinin (DATM) were observed...
Different stimulatory opioid effects on intracellular Ca(2+) in SH-SY5Y cellsL Chen
Institute of Biophysics and Biochemistry, Huazhong University of Science and Technology, 430074, Wuhan, PR China
Brain Res 882:256-65. 2000..All these indicated the opioid modulated the intracellular Ca(2+) regulation system through different pathways. SH-SY5Y cell line might be a suitable model for the investigation of the complex mechanism which underlies opioid function...
Fluorimetry determination of trace Ce3+ with EDTPJ X Meng
Department of Chemistry, Jinan University, Guangzhou, PR China
Spectrochim Acta A Mol Biomol Spectrosc 56:1925-8. 2000..The quenching effects of coexist ions (other rare earth ions, Fe3+ and some inorganic anions) were studied. This technique has unique advantage in eliminating disturb of coexist...
[Longitudinal biomechanical effect on repair options of artery injury]Q Jie
Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi an Shanxi, P R China 710032
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 14:132-4. 2000..To investigate the relationship between the different defect length of vessels and the options of vascular repair, and to compare the different options of repair because of the longitudinal biomechanical effect...
[Therapeutic vitrectomy for severe uveitis and its complications]Jiaqing Li
Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China
Zhonghua Yan Ke Za Zhi 38:204-6. 2002..To investigate the therapeutic value of vitrectomy for uveitis and its complications...
The link between psychosocial factors and functional dyspepsia: an epidemiological studyYuyuan Li
Division of Gastroenterology, First Municipal People s Hospital of Guangzhou, Guangzhou 510180, China
Chin Med J (Engl) 115:1082-4. 2002..To investigate the prevalence of functional dyspepsia (FD) and the psychological disorders in Chinese population and their relation...
[Advances in the research on sources and sinks of CH4 and CH4 oxidation (uptake) in soil]Chenrui Wang
Key Laboratory of Terrestrial Ecological Process, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016
Ying Yong Sheng Tai Xue Bao 13:1707-12. 2002..It is significant that studying CH4 oxidation in vertical zonation soil in forests of Changbai Mountain to evaluate the CH4 consumption in forest soil...
[Determination and calculation of evapotranspiration of broad-leaved Korean pine forest on Changbai Mountain]Anzhi Wang
Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016
Ying Yong Sheng Tai Xue Bao 13:1547-50. 2002..9 mm. Furthermore, the daily Et and hourly Et rate were computed by BREB method, and the availability and precision of the Et determined by water balance and calculated by BREB method was discussed...
The influence of Enteral Nutrition in postoperative patients with poor liver functionQing gang Hu
Department of Surgery, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province China
World J Gastroenterol 9:843-6. 2003..To investigate the safety, rationality and the practicality of enteral nutritional (EN) support in the postoperative patients with damaged liver function and the protective effect of EN on the gut barrier...
Neuroprotective effects of nimodipine and MK-801 on acute infectious brain edema induced by injection of pertussis bacilli to neocortex of ratsLi Hua Chen
Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China
Chin J Traumatol 6:118-23. 2003....
A clinical and patch test study of adult widespread eczemaLin feng Li
Department of Dermatology, Peking University The Third Hospital, Beijing, China
Contact Dermatitis 47:341-4. 2002..Neglected widespread contact with contact allergens, especially hair dye, plays a very important role in our adult WE. The roles of age and sex in WE need to be studied further...
[Screening and identification for cDNA of differentially expressed genes in human primary hepatocellular carcinoma]Jing Li
Department of Hepatobiliary Surgery of Xinqiao Hospital, Third Military Medical University, Chongqing, PR China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20:49-52. 2003..Screening and identification of differentially expressed genes in human primary hepatocellular carcinoma(HCC)...
[Determination of serum granulocyte colony-stimulating factor level in patients with chronic idiopathic neutropenia and its significance]Chun Sen Wang
Department of Hematology, Sichuan Provincial People s Hospital, Chengdu 610072, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 10:373-4. 2002..04 +/- 89.29) ng/L, which was higher than that in the normal controls and the cases with SLE (P < 0.01). It was concluded that an obstacle to utilization of G-CSF could be existed in the patients with CIN...
[Effect of G-CSF and GM-CSF on expression of TNF-alpha mRNA and CD69 and secretion of IgG in peripheral blood mononuclear cells from systemic lupus erythematosus patients]Chun Lu
Department of Dermatology, The Third Affiliated Hospital of Sun Yat Sen University, Guangzhou 510630, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 10:531-4. 2002..It was concluded that G-CSF as a mobilization agent could be safe to SLE patients, but GM-CSF may cause some harmful effects to patients because of the increase of the parameters relating to activity of lupus in active SLE patients...
Patch testing in allergic contact dermatitis caused by topical Chinese herbal medicineL-F Li
Department of Dermatology, Peking University The Third Hospital, Beijing, China
Contact Dermatitis 47:166-8. 2002
Contact hypersensitivity in hand dermatitisLin feng Li
Department of Dermatology, Peking University The Third Hospital, Beijing, People s Republic of China
Contact Dermatitis 47:206-9. 2002..Only a small proportion of the HD patients could report the suspected offending agents and PT should be performed in all patients with chronic HD...
[A study on localization of an autosomal dominant retinitis pigmentosa gene]Xiaoye Ma
Department of Ophthalmology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
Zhonghua Yan Ke Za Zhi 38:680-3. 2002..To report the localization of a gene for an autosomal dominant retinitis pigmentosa (ADRP) family...
Effects and mechanisms of melatonin on inflammatory and immune responses of adjuvant arthritis ratQun Chen
Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
Int Immunopharmacol 2:1443-9. 2002..To study the effects of melatonin on inflammatory and immune responses and its mechanisms...
[A new point mutation on exon 2 of parkin gene in Parkinson's disease]Yanming Xu
Department of Neurology, The First Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong, 510080 P R China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 19:409-11. 2002..To detect the relationship between point mutations on exon 2 of parkin gene and sporadic early-onset Parkinson's disease...
Determination of divalent carboxylic acids in traditional Chinese herbal and patent medicines using HPLC with double cell quartz crystal detectorP Chen
New Materials Research Institute, Hunan University, Changsha, People s Republic of China
J Pharm Biomed Anal 23:387-93. 2000..The DCQC detector has a low temperature coefficient and high conductance sensitivity independent of the background from 7.2 to 2500 microS. Analysis of sample is completed without the use of an ion suppression device...
