Hong yi Qi
Affiliation: Southwest University
Li L, Yang Y, Wu M, Yu Z, Wang C, Dou G, et al
. β-Asarone Induces Apoptosis and Cell Cycle Arrest of Human Glioma U251 Cells via Suppression of HnRNP A2/B1-Mediated Pathway In Vitro and In Vivo. Molecules. 2018;23: pubmed publisher
..Together, β-asarone-induced apoptosis and cell cycle arrest of U251 cells may be related to the suppression of hnRNPA2/B1-mediated signaling pathway. ..
Qi H, Chen L, Ning L, Ma H, Jiang Z, Fu Y, et al
. Proteomic analysis of Î²-asarone induced cytotoxicity in human glioblastoma U251 cells. J Pharm Biomed Anal. 2015;115:292-9 pubmed publisher
..Four potential protein targets were proposed, which will enable a better understanding of the anti-tumor activity of Î²-asarone. ..
Ning L, Ma H, Jiang Z, Chen L, Li L, Chen Q, et al
. Curcumol Suppresses Breast Cancer Cell Metastasis by Inhibiting MMP-9 Via JNK1/2 and Akt-Dependent NF-?B Signaling Pathways. Integr Cancer Ther. 2016;15:216-25 pubmed publisher
..Our findings provide evidence for the suppression of breast cancer cell metastasis by curcumol and suggest that the inhibition of MMP-9 via JNK1/2 and Akt (Ser473)-dependent NF-?B signaling pathways may be the underlying mechanisms. ..
Li L, Wu M, Wang C, Yu Z, Wang H, Qi H, et al
. β-Asarone Inhibits Invasion and EMT in Human Glioma U251 Cells by Suppressing Splicing Factor HnRNP A2/B1. Molecules. 2018;23: pubmed publisher
..Together, our results suggest that hnRNP A2/B1 may be a potential molecular target underlying the inhibitory effect of β-asarone on invasion and EMT in glioma cells. ..