Xia Li

Summary

Affiliation: Southern Medical University
Country: China

Publications

  1. ncbi request reprint Cloning and sequence analysis of Bacillus thuringiensis gene fragments isolated by restriction digest PCR
    Xia Li
    Institute of Molecular Biochemistry, First Military Medical University, Guangzhou 510515, China
    Di Yi Jun Yi Da Xue Xue Bao 23:323-5. 2003
  2. pmc Cats lack a sweet taste receptor
    Xia Li
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    J Nutr 136:1932S-1934S. 2006
  3. ncbi request reprint Oligonucleotide microarray with RD-PCR labeling technique for detection and typing of human papillomavirus
    Wei Min
    Institute of Molecular Biology, Southern Medical University, Guangzhou, 510515, P R China
    Curr Microbiol 52:204-9. 2006
  4. ncbi request reprint An oligonucleotide microarray for the detection of vaccinia virus
    M Wenli
    Institute of Molecular Biology, First Uniform Medical University, Guangzhou 510515, PR China
    Br J Biomed Sci 61:142-5. 2004
  5. pmc A high-resolution map of segmental DNA copy number variation in the mouse genome
    Timothy A Graubert
    Department of Medicine, Division of Oncology, Stem Cell Biology Section, Washington University, St Louis, Missouri, United States of America
    PLoS Genet 3:e3. 2007
  6. ncbi request reprint Effects of replacing the unreliable cDNA microarray measurements on the disease classification based on gene expression profiles and functional modules
    Dong Wang
    Department of Bioinformatics and Bio pharmaceutical Key Laboratory of Heilongjiang Province and State, Harbin Medical University Harbin 150086, China
    Bioinformatics 22:2883-9. 2006
  7. pmc Is glycine "sweet" to mice? Mouse strain differences in perception of glycine taste
    Satoshi Manita
    Laboratory of Cellular Neurobiology, School of Life Sciences, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo 192 0392, Japan
    Chem Senses 31:785-93. 2006
  8. ncbi request reprint Expression and characterization of a thermostable sarcosine oxidase (SOX) from Bacillus sp. in Escherichia coli
    Kangping Guo
    College of Life Sciences, Zhejiang University, No 268, Kaixuan Road, Hangzhou 310029, People s Republic of China
    Appl Microbiol Biotechnol 73:559-66. 2006
  9. ncbi request reprint Novel mutations found in mitochondrial diabetes in Chinese Han population
    Song mei Liu
    Genetic Diagnosis Center, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, PR China
    Diabetes Res Clin Pract 76:425-35. 2007
  10. ncbi request reprint [Development of a DNA chip screening mitochondrial DNA mutations in patients with diabetes mellitus]
    Song mei Liu
    Genetic Diagnosis Center, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
    Zhonghua Yi Xue Za Zhi 86:2853-7. 2006

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Cloning and sequence analysis of Bacillus thuringiensis gene fragments isolated by restriction digest PCR
    Xia Li
    Institute of Molecular Biochemistry, First Military Medical University, Guangzhou 510515, China
    Di Yi Jun Yi Da Xue Xue Bao 23:323-5. 2003
    ..To clone and analyze Bacillus thuringiensis gene fragments isolated by restriction digest PCR (RD-PCR)...
  2. pmc Cats lack a sweet taste receptor
    Xia Li
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    J Nutr 136:1932S-1934S. 2006
  3. ncbi request reprint Oligonucleotide microarray with RD-PCR labeling technique for detection and typing of human papillomavirus
    Wei Min
    Institute of Molecular Biology, Southern Medical University, Guangzhou, 510515, P R China
    Curr Microbiol 52:204-9. 2006
    ..The application of RD-PCR in the sample labeling can increase significantly the sensitivity of the assay and will be especially useful for the discriminate diagnosis of multiple pathogens...
  4. ncbi request reprint An oligonucleotide microarray for the detection of vaccinia virus
    M Wenli
    Institute of Molecular Biology, First Uniform Medical University, Guangzhou 510515, PR China
    Br J Biomed Sci 61:142-5. 2004
    ..The results showed that the oligonucleotide microarray can detect vaccinia virus with high specificity and sensitivity...
  5. pmc A high-resolution map of segmental DNA copy number variation in the mouse genome
    Timothy A Graubert
    Department of Medicine, Division of Oncology, Stem Cell Biology Section, Washington University, St Louis, Missouri, United States of America
    PLoS Genet 3:e3. 2007
    ..Annotation of CNVs in the mouse genome combined with sequence-based analysis provides an important resource that will help define the genetic basis of complex traits...
  6. ncbi request reprint Effects of replacing the unreliable cDNA microarray measurements on the disease classification based on gene expression profiles and functional modules
    Dong Wang
    Department of Bioinformatics and Bio pharmaceutical Key Laboratory of Heilongjiang Province and State, Harbin Medical University Harbin 150086, China
    Bioinformatics 22:2883-9. 2006
    ..The focus of the paper is to study the effects of different MV treatments for cDNA microarray data on disease classification analysis...
  7. pmc Is glycine "sweet" to mice? Mouse strain differences in perception of glycine taste
    Satoshi Manita
    Laboratory of Cellular Neurobiology, School of Life Sciences, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo 192 0392, Japan
    Chem Senses 31:785-93. 2006
    ....
  8. ncbi request reprint Expression and characterization of a thermostable sarcosine oxidase (SOX) from Bacillus sp. in Escherichia coli
    Kangping Guo
    College of Life Sciences, Zhejiang University, No 268, Kaixuan Road, Hangzhou 310029, People s Republic of China
    Appl Microbiol Biotechnol 73:559-66. 2006
    ..The study also showed that an increased number of alanine residues in the rSOX might have some contribution in the enzymatic thermostability...
  9. ncbi request reprint Novel mutations found in mitochondrial diabetes in Chinese Han population
    Song mei Liu
    Genetic Diagnosis Center, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, PR China
    Diabetes Res Clin Pract 76:425-35. 2007
    ..418). Our study suggested that T3394C and A12026G might be associated with T2DM in Chinese Han population, and T2DM with mtDNA variant should be considered mitochondrial diabetes...
  10. ncbi request reprint [Development of a DNA chip screening mitochondrial DNA mutations in patients with diabetes mellitus]
    Song mei Liu
    Genetic Diagnosis Center, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
    Zhonghua Yi Xue Za Zhi 86:2853-7. 2006
    ..To establish a rapid and precise high-throughput mitochondrial (mt) DNA chip and to investigate the relationship between mtDNA tRNA Leu (UUR) and ND1 gene mutations and diabetes mellitus...
  11. doi request reprint Apparently low reproducibility of true differential expression discoveries in microarray studies
    Min Zhang
    School of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150086, China
    Bioinformatics 24:2057-63. 2008
    ..Even in technical replicate tests using identical samples, DEG detection still shows very low reproducibility. It is often believed that current small microarray studies will largely introduce false discoveries...
  12. ncbi request reprint Genetic variation of Bmy1 alleles in barley (Hordeum vulgare L.) investigated by CAPS analysis
    Wen Sheng Zhang
    The State Key Laboratory of Plant Cell and Chromosome Engineering, Center for Agricultural Resources Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, People s Republic of China
    Theor Appl Genet 114:1039-50. 2007
    ..Remarkably, very low Bmy1 genetic variation was detected in Tibetan barleys, which puts the validity of the hypothesis that Tibet is one of the original centers of cultivated barley into question...
  13. pmc Association between embB codon 306 mutations and drug resistance in Mycobacterium tuberculosis
    Xin Shen
    Key Laboratory of Medical Molecular Virology, Shanghai Medical College, Fudan University, Shanghai 20032, China
    Antimicrob Agents Chemother 51:2618-20. 2007
    ..78; P < 0.001). The embB306 locus is a candidate marker for rapid detection of MDR and extremely drug resistant tuberculosis...
  14. pmc Unravelling the hidden heterogeneities of diffuse large B-cell lymphoma based on coupled two-way clustering
    Wei Zhang
    The First Clinical College, Department of Bioinformatics, and the Bio pharmaceutical Key Laboratory of Heilongjiang Province and State, Harbin Medical University, Harbin 150086, China
    BMC Genomics 8:332. 2007
    ....
  15. pmc Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice
    Masashi Inoue
    Laboratory of Cellular Neurobiology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
    Physiol Genomics 32:82-94. 2007
    ....
  16. ncbi request reprint Data mining of RNA expression and DNA genotype data: presentation group 5 contributions to Genetic Analysis Workshop 15
    Catherine T Falk
    Genet Epidemiol 31:S43-50. 2007
    ..The collection of papers and methods offer a starting point for further exploration of complex interactions in human genetic data now readily available...
  17. doi request reprint Isolation and characterization of Methanoculleus receptaculi sp. nov. from Shengli oil field, China
    Lei Cheng
    Biogas Institute of Ministry of Agriculture, Chengdu, China
    FEMS Microbiol Lett 285:65-71. 2008
    ..nov. The type strain is ZC-2T (CGMCC 1.5087T=DSM 18860T)...
  18. ncbi request reprint Rapid prenatal diagnosis of trisomy 21 by fluorescent quantitative multiplex polymerase chain reaction
    Fang Zheng
    Gene Diagnosis Center, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
    Chin Med J (Engl) 119:514-7. 2006
  19. ncbi request reprint [Preliminary analysis on the gene expression profiles of different types of gliomas with cDNA array]
    Rong cai Jiang
    Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin 300052, P R China
    Ai Zheng 21:1085-9. 2002
    ..The cDNA was used in order to detect the differences in gene expression profiles of different types of gliomas...
  20. pmc Loci on chromosomes 2, 4, 9, and 16 for body weight, body length, and adiposity identified in a genome scan of an F2 intercross between the 129P3/J and C57BL/6ByJ mouse strains
    Danielle R Reed
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, Pennsylvania 19104, USA
    Mamm Genome 14:302-13. 2003
    ..These results reinforce the concept that obesity is a complex trait. Genetic loci and their interactions, in conjunction with sex, age, and diet, determine body size and adiposity in mice...
  21. ncbi request reprint Apolipoprotein E genotype in patients with Alzheimer's disease
    Benyan Luo
    Department of Neurology, First Affiliated Hospital, Medical College of Zhejiang University, Hangzhou 310003, China
    Chin Med J (Engl) 116:1220-2. 2003
    ..To explore the frequency and significance of ApoE gene polymorphisms in patients with sporadic Alzheimer's disease (AD)...
  22. ncbi request reprint Synthesis of beta-substituted cationic porphyrins and their interactions with DNA
    Bo Chen
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei Wuhan 430072, P R China
    Bioorg Med Chem Lett 13:3731-3. 2003
    ..We found that substituents at the beta-position of porphyrins (7 and 8) have apparently affected their interactions with DNA compared with non-beta-substituted porphyrins (10)...
  23. ncbi request reprint Study of apolipoprotein E genetic polymorphism in patients with atherosclerotic cerebral infarction
    Ben Yan Luo
    Department of Neurology, The First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310003, China
    J Zhejiang Univ Sci 4:749-52. 2003
    ..To explore the frequency and significance of ApoE gene polymorphisms in Chinese patients with atherosclerotic cerebral infarction (ACI)...
  24. pmc Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice
    Masashi Inoue
    Laboratory of Cellular Neurobiology, School of Life Science, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo 192 0392, Japan
    J Neurosci 24:2296-303. 2004
    ..This study describes the range of ligand sensitivity of the T1R3 receptor using an in vivo approach and, to our knowledge, is the first genetic mapping study of activity in gustatory nerves...
  25. ncbi request reprint [Preventive effects of pioglitazone on diabetes and relevant mechanisms, experimental study on non-obese diabetic mice]
    Jian hao Pei
    Institute of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011, China
    Zhonghua Yi Xue Za Zhi 84:411-5. 2004
    ..To explore the effects of pioglitazone on insulitis and diabetes and relevant mechanism...
  26. pmc Gene mining: a novel and powerful ensemble decision approach to hunting for disease genes using microarray expression profiling
    Xia Li
    Department of Biomedical Engineering, Biomathematics and Bioinformatics, Harbin Medical University, Harbin 150086, China
    Nucleic Acids Res 32:2685-94. 2004
    ..Establishment of this analysis strategy has offered the promise of advancing microarray technology as a means of deciphering the involved genetic complexities of complex diseases...
  27. ncbi request reprint A robust hybrid between genetic algorithm and support vector machine for extracting an optimal feature gene subset
    Li Li
    Department of Bioinformatics, Harbin Medical University, Harbin 150086, People s Republic of China
    Genomics 85:16-23. 2005
    ....
  28. ncbi request reprint An ensemble method for gene discovery based on DNA microarray data
    Xia Li
    Department of Computer Science, Harbin Institute of Technology, Harbin 150001, China
    Sci China C Life Sci 47:396-405. 2004
    ..We also give a numerical application for (i) and (ii) using a public microarrary data set and set aside a separate paper to address (iii)...
  29. ncbi request reprint [Analysis of the mRNA expression similarity of genes in the same gene expression regulatory pathway]
    Chuan Xing Li
    Department of Bioinformatics, Harbin Medical University, Harbin 150086, China
    Yi Chuan 26:929-33. 2004
    ....
  30. ncbi request reprint Dehydration anorexia is attenuated in oxytocin-deficient mice
    Linda Rinaman
    University of Pittsburgh, Department of Neuroscience, 446 Crawford Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1791-9. 2005
    ..These findings support the view that OT-containing projections from the hypothalamus to the hindbrain are necessary for the full expression of compensatory behavioral and physiological responses to dehydration...
  31. pmc Towards precise classification of cancers based on robust gene functional expression profiles
    Zheng Guo
    Department of Computer Science, Harbin Institute of Technology, Harbin 150001, China
    BMC Bioinformatics 6:58. 2005
    ..Therefore, there is an open space for development of the timely and relevant computational algorithms that use robust functional expression profiles towards precise classification of complex human diseases at the modular level...
  32. ncbi request reprint Cloning, expression, isotope labeling, and purification of human antimicrobial peptide LL-37 in Escherichia coli for NMR studies
    Yifeng Li
    The Structure Fun Laboratory, Eppley Institute for Research in Cancer and Allied Diseases, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, 68198 6805, USA
    Protein Expr Purif 47:498-505. 2006
    ..The successful application to the expression of the 66-residue cytoplasmic tail of human MUC1 indicates that the system can be applied to other peptides as well...
  33. pmc Discovery of Time-Delayed Gene Regulatory Networks based on temporal gene expression profiling
    Xia Li
    Department of Bioinformatics, Harbin Medical University, Harbin 150086, PR China
    BMC Bioinformatics 7:26. 2006
    ..The vast amount of large-scale and genome-wide time-resolved data is becoming increasing available, which provides the golden opportunity to unravel the challenging reverse-engineering problem of time-delayed gene regulatory networks...
  34. pmc Constructing disease-specific gene networks using pair-wise relevance metric: application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements
    Wei Jiang
    College of Bioinformatics Science and Technology and Bio pharmaceutical Key Laboratory of Heilongjiang Province, Harbin Medical University, Harbin 150081, PR China
    BMC Syst Biol 2:72. 2008
    ..The aim of this study was thus to develop such a novel networking approach based on the relevance concept, which is ideal to reveal integrative effects of multiple genes in the underlying genetic circuit for complex diseases...