Affiliation: Southeast University
Wang C, Ge L, Wu J, Wang X, Yuan L. MiR-219 represses expression of dFMR1 in Drosophila melanogaster. Life Sci. 2018;: pubmed publisher
..Collectively, these findings expand the current understanding of miRNA-mediated regulation of target molecule-related functions. ..
Wang C, Feng T, Wan Q, Kong Y, Yuan L. miR-124 controls Drosophila behavior and is required for neural development. Int J Dev Neurosci. 2014;38:105-12 pubmed publisher
Qian J, Tu R, Yuan L, Xie W. Intronic miR-932 targets the coding region of its host gene, Drosophila neuroligin2. Exp Cell Res. 2016;344:183-93 pubmed publisher
..This study would be valuable in elucidating the regulation of intronic miRNA on host gene, and provide new information about the biological context of their genomic arrangements and functions. ..
Song H, Zhang Y, Liu N, Wan C, Zhang D, Zhao S, et al
. miR-92b regulates glioma cells proliferation, migration, invasion, and apoptosis via PTEN/Akt signaling pathway. J Physiol Biochem. 2016;72:201-11 pubmed publisher
..Further investigations will focus on antitumor effect of miRâ€‘92b-I in glioma treatment. ..
Song H, Zhang Y, Liu N, Zhang D, Wan C, Zhao S, et al
. Let-7b inhibits the malignant behavior of glioma cells and glioma stem-like cells via downregulation of E2F2. J Physiol Biochem. 2016;72:733-744 pubmed
..In conclusion, we suggest that Let-7b could be developed into a promising anticancer target in glioma. ..
Song H, Zhang Y, Liu N, Zhao S, Kong Y, Yuan L. miR-92a-3p Exerts Various Effects in Glioma and Glioma Stem-Like Cells Specifically Targeting CDH1/?-Catenin and Notch-1/Akt Signaling Pathways. Int J Mol Sci. 2016;17: pubmed
..These results suggest that miR-92a-3p plays different roles in glioma cells and GSCs through regulating different signaling pathways. ..