Ran Liu

Summary

Affiliation: Southeast University
Country: China

Publications

  1. pmc Tumor-suppressive function of miR-139-5p in esophageal squamous cell carcinoma
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    PLoS ONE 8:e77068. 2013
  2. pmc Identification of Plasma Metabolomic Profiling for Diagnosis of Esophageal Squamous-Cell Carcinoma Using an UPLC/TOF/MS Platform
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, Jiangsu, China
    Int J Mol Sci 14:8899-911. 2013
  3. pmc Association between gene expression of metabolizing enzymes and esophageal squamous cell carcinomas in China
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, P R China
    Genet Test Mol Biomarkers 16:1211-7. 2012
  4. doi request reprint Circulating miR-155 expression in plasma: a potential biomarker for early diagnosis of esophageal cancer in humans
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    J Toxicol Environ Health A 75:1154-62. 2012
  5. pmc The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    PLoS ONE 7:e33987. 2012
  6. doi request reprint Differential expression profiles of microRNAs as potential biomarkers for the early diagnosis of esophageal squamous cell carcinoma
    Miao Yang
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, PR China
    Oncol Rep 29:169-76. 2013
  7. doi request reprint Malignant progression in O6-methylguanine-DNA methyltransferase-deficient esophageal cancer cells is associated with Ezrin protein
    Yaoyao Su
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    DNA Cell Biol 31:856-66. 2012
  8. doi request reprint Functional alterations in the glutathione S-transferase family associated with enhanced occurrence of esophageal carcinoma in China
    Ran Liu
    Department of Occupational and Environmental Health, School of Public Health, Southeast University, Nanjing, People s Republic of China
    J Toxicol Environ Health A 73:471-82. 2010
  9. doi request reprint Chlorpyrifos exposure reduces reproductive capacity owing to a damaging effect on gametogenesis in the nematode Caenorhabditis elegans
    Qin Li Ruan
    Key Laboratory of Environmental Medicine Engineering in Ministry of Education, Department of Occupational and Environmental Health, School of Public Health, Southeast University, Nanjing, China
    J Appl Toxicol 32:527-35. 2012
  10. ncbi request reprint Individual and combined developmental toxicity assessment of bisphenol A and genistein using the embryonic stem cell test in vitro
    Dan Kong
    Department of Toxicology, School of Public Health, Peking University, Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing 100191, China
    Food Chem Toxicol 60:497-505. 2013

Collaborators

Detail Information

Publications29

  1. pmc Tumor-suppressive function of miR-139-5p in esophageal squamous cell carcinoma
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    PLoS ONE 8:e77068. 2013
    ....
  2. pmc Identification of Plasma Metabolomic Profiling for Diagnosis of Esophageal Squamous-Cell Carcinoma Using an UPLC/TOF/MS Platform
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, Jiangsu, China
    Int J Mol Sci 14:8899-911. 2013
    ....
  3. pmc Association between gene expression of metabolizing enzymes and esophageal squamous cell carcinomas in China
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, P R China
    Genet Test Mol Biomarkers 16:1211-7. 2012
    ..Reduced expression of GSTP1 in PBMCs was significantly associated with the risk for ESCC, suggesting an important etiology clue to the early progression of ESCC in the Huaian population of China...
  4. doi request reprint Circulating miR-155 expression in plasma: a potential biomarker for early diagnosis of esophageal cancer in humans
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    J Toxicol Environ Health A 75:1154-62. 2012
    ..In conclusion, results suggest that circulating miR-155 in plasma may serve as a reliable, novel, noninvasive biomarker for early diagnosis and detection of esophageal cancer...
  5. pmc The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    PLoS ONE 7:e33987. 2012
    ....
  6. doi request reprint Differential expression profiles of microRNAs as potential biomarkers for the early diagnosis of esophageal squamous cell carcinoma
    Miao Yang
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, PR China
    Oncol Rep 29:169-76. 2013
    ..Differential expression profiles of miRNAs in ESCC may be promising biomarkers for the early screening of high-risk populations and early detection...
  7. doi request reprint Malignant progression in O6-methylguanine-DNA methyltransferase-deficient esophageal cancer cells is associated with Ezrin protein
    Yaoyao Su
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    DNA Cell Biol 31:856-66. 2012
    ..In conclusion, loss of MGMT expression leads EC109 esophageal cancer cells to have increased malignant behavior, which may correlate with its high Ezrin protein expression...
  8. doi request reprint Functional alterations in the glutathione S-transferase family associated with enhanced occurrence of esophageal carcinoma in China
    Ran Liu
    Department of Occupational and Environmental Health, School of Public Health, Southeast University, Nanjing, People s Republic of China
    J Toxicol Environ Health A 73:471-82. 2010
    ..Data thus suggest that the CpG island hypermethylation of promoter gene may serve as a useful biomarker for early diagnosis of esophageal carcinoma development...
  9. doi request reprint Chlorpyrifos exposure reduces reproductive capacity owing to a damaging effect on gametogenesis in the nematode Caenorhabditis elegans
    Qin Li Ruan
    Key Laboratory of Environmental Medicine Engineering in Ministry of Education, Department of Occupational and Environmental Health, School of Public Health, Southeast University, Nanjing, China
    J Appl Toxicol 32:527-35. 2012
    ..Hence, the model organism Caenorhabditis elegans is recommended for assessment of reproductive toxicity relating to gametogenesis...
  10. ncbi request reprint Individual and combined developmental toxicity assessment of bisphenol A and genistein using the embryonic stem cell test in vitro
    Dan Kong
    Department of Toxicology, School of Public Health, Peking University, Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Beijing 100191, China
    Food Chem Toxicol 60:497-505. 2013
    ..However, given that BPA and GEN do have synergistic effect at low concentration, they may disturb normal embryo development together, which could result in birth defect and behavioral alterations later in life. ..
  11. doi request reprint Promoter methylation status of MGMT, hMSH2, and hMLH1 and its relationship to corresponding protein expression and TP53 mutations in human esophageal squamous cell carcinoma
    Yaoyao Su
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China
    Med Oncol 31:784. 2014
    ..However, such relevance was not found for hMLH1. Furthermore, TP53 mutation status was well associated with MGMT and hMSH2 promoter methylation status, indicating that silencing of the two genes could lead to TP53 mutation in ESCC. ..
  12. pmc A promising strategy for overcoming MDR in tumor by magnetic iron oxide nanoparticles co-loaded with daunorubicin and 5-bromotetrandrin
    Jian Cheng
    Department of Hematology, Zhongda Hospital, Medical School, Southeast University, Nanjing, People s Republic of China
    Int J Nanomedicine 6:2123-31. 2011
    ....
  13. ncbi request reprint Neurotoxicological evaluation of microcystin-LR exposure at environmental relevant concentrations on nematode Caenorhabditis elegans
    Jingjuan Ju
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China
    Environ Sci Pollut Res Int 20:1823-30. 2013
    ..MC-LR at environmental relevant concentrations caused neurobehavioral defects, which may be largely due to the neuronal loss and the alterations of expression level of genes required for GABAergic neurotransmitter system in C. elegans...
  14. doi request reprint Detection of CYP2E1, a genetic biomarker of susceptibility to benzene metabolism toxicity in immortal human lymphocytes derived from the Han Chinese Population
    Juan Zhang
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu, China
    Biomed Environ Sci 24:300-9. 2011
    ....
  15. ncbi request reprint Small-sized titanium dioxide nanoparticles mediate immune toxicity in rat pulmonary alveolar macrophages in vivo
    Ran Liu
    School of Public Health, Southeast University, Nanjing 210009, China
    J Nanosci Nanotechnol 10:5161-9. 2010
    ....
  16. doi request reprint Detection of quinone oxidoreductase 1 (NQO1) single-nucleotide polymorphisms (SNP) related to benzene metabolism in immortalized B lymphocytes from a Chinese Han population
    Juan Zhang
    Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, People s Republic of China
    J Toxicol Environ Health A 73:490-8. 2010
    ..The immortalized B lymphocytes derived from different populations might thus be used as a biomarker to detect functional genetic markers related to exposure to environmental chemicals...
  17. doi request reprint Effects of subchronic exposure to multi-walled carbon nanotubes on mice
    Geyu Liang
    Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    J Toxicol Environ Health A 73:463-70. 2010
    ..Data in the present study support the view that MWCNT in vivo do not exert apparent marked effects in mice and that MWCNT products are relatively safe for human consumption...
  18. ncbi request reprint Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Huai'an population, China
    Ran Liu
    School of Public Health, Southeast University, Nanjing 210009, China
    Chin Med J (Engl) 120:1797-802. 2007
    ..This study examined whether CYP2E1 RsaI and DraI polymorphism are associated with susceptibility to esophageal squamous cell carcinoma and the correlation between the genotypes and expression levels of CYP2E1 mRNA...
  19. ncbi request reprint Rapid and sensitive suspension array for multiplex detection of organophosphorus pesticides and carbamate pesticides based on silica-hydrogel hybrid microbeads
    Xuan Wang
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu, China
    J Hazard Mater 273:287-92. 2014
    ..Our results showed that this simple method is suitable for simultaneous detection of these five pesticides residues in fruits and vegetables. ..
  20. pmc Melatonin enhances DNA repair capacity possibly by affecting genes involved in DNA damage responsive pathways
    Ran Liu
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China
    BMC Cell Biol 14:1. 2013
    ..Melatonin, a hormone-like substance involved in the regulation of the circadian rhythm, has been demonstrated to protect cells against oxidative DNA damage and to inhibit tumorigenesis...
  21. pmc Effect of magnetic nanoparticles on apoptosis and cell cycle induced by wogonin in Raji cells
    Lei Wang
    Department of Hematology and Oncology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China
    Int J Nanomedicine 7:789-98. 2012
    ..These findings suggest that the combination of wogonin and MNPs provides a promising strategy for lymphoma therapy...
  22. doi request reprint Poloxamer-188 attenuates TBI-induced blood-brain barrier damage leading to decreased brain edema and reduced cellular death
    Hai Jun Bao
    Institute of Forensic Sciences, Soochow University, Suzhou 215123, Jiangsu, China
    Neurochem Res 37:2856-67. 2012
    ..Plasmalemma permeability may be a potential target for TBI treatment...
  23. ncbi request reprint Reduced expression of human DNA repair genes in esophageal squamous-cell carcinoma in china
    Ran Liu
    Department of Environmental Health, School of Public Health, Southeast University, Nanjing, China
    J Toxicol Environ Health A 70:956-63. 2007
    ....
  24. ncbi request reprint [Reversal effect of gambogic acid on multidrug resistance of K562/A02 cell line]
    Liang Tian
    Department of Hematology and Oncology, Southeast University Clinical Medical College, Nanjing, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 20:252-7. 2012
    ..It is concluded that GA can enhance the sensitivity of K562/A02 cells to ADM, which may be related to increasing cell apoptosis and down-regulating expressions of Survivin and P-gp...
  25. doi request reprint Molecular imprinted photonic crystal hydrogels for the rapid and label-free detection of imidacloprid
    Xuan Wang
    Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, PR China
    Food Chem 141:3947-53. 2013
    ..This sensor which comprises of no label techniques and expensive instruments has potential application for the detection of trace imidacloprid...
  26. doi request reprint Combined developmental toxicity of bisphenol A and genistein in micromass cultures of rat embryonic limb bud and midbrain cells
    Yang Xiao
    Department of Toxicology, School of Public Health, Peking University, Beijing, China
    Toxicol In Vitro 25:153-9. 2011
    ..While the evidence of GEN as a teratogen was solid, especially with the consideration of "high dose" application in clinical treatment. The combined effect of BPA and GEN was generally additive action except that in MB proliferation...
  27. doi request reprint Evaluation of pesticide toxicities with differing mechanisms using Caenorhabditis elegans
    Qin Li Ruan
    Department of Occupation and Environmental Health, School of Public Health, Southeast University, Nanjing, China
    J Toxicol Environ Health A 72:746-51. 2009
    ..The effects of pesticides on nematodes exposed for 24 h appeared more sensitive than with exposure for 72 h. Caenorhabditis elegans may thus be used for assessing the adverse effects of pesticide residues in aquatic environment...
  28. doi request reprint Influence of different sizes of titanium dioxide nanoparticles on hepatic and renal functions in rats with correlation to oxidative stress
    Geyu Liang
    School of Public Health, Southeast University, Nanjing, People s Republic of China
    J Toxicol Environ Health A 72:740-5. 2009
    ..There was no apparent evidence that TiO(2-S210) was more toxic than TiO(2-S50). In general, intratracheal exposure to TiO(2) did not markedly affect extrapulmonary tissue functions...
  29. pmc Synthesis and antitumor efficacy of daunorubicin-loaded magnetic nanoparticles
    Jun Wang
    Department of Hematology and Oncology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, China
    Int J Nanomedicine 6:203-11. 2011
    ..A promising approach to optimize the disposition of daunorubicin-loaded magnetic nanoparticles (DNR-MNPs) was developed to minimize serious side effects of systematic chemotherapy for cancer...