Genomes and Genes


Zhiming Xiang


Affiliation: South China Sea Institute of Oceanology
Country: China


  1. Wang F, Xiao S, Zhang Y, Zhang Y, Liu Y, Yan Y, et al. ChAkt1 involvement in orchestrating the immune and heat shock responses in Crassostrea hongkongensis: Molecular cloning and functional characterization. Fish Shellfish Immunol. 2015;47:1015-23 pubmed publisher
    ..Taken together, our results indicate that ChAkt1 most likely plays a central role in response to various stimuli in oysters and has a particular response to microbial pathogens and high temperature. ..
  2. Qu F, Xiang Z, Zhang Y, Li J, Xiao S, Zhang Y, et al. A novel p38 MAPK indentified from Crassostrea hongkongensis and its involvement in host response to immune challenges. Mol Immunol. 2016;79:113-124 pubmed publisher
    ..Altogether, these results provide the first experimental evidence of a functional p38 in oysters and suggest its involvement in the innate immunity of C. hongkongensis. ..
  3. Qi L, Xiang Z. Molecular cloning and expression analysis of an apoptosis-associated gene Daxx from zebrafish, Danio rerio. Fish Shellfish Immunol. 2015;45:59-66 pubmed publisher
    ..These results suggested that Daxx might play definite role in apoptosis and innate immunity in zebrafish. ..
  4. Qu F, Xiang Z, Xiao S, Wang F, Li J, Zhang Y, et al. c-Jun N-terminal kinase (JNK) is involved in immune defense against bacterial infection in Crassostrea hongkongensis. Dev Comp Immunol. 2017;67:77-85 pubmed publisher
    ..In summary, this study provided the first experimental demonstration that oysters possess a functional JNK that participates in host defense against bacterial infection in C. hongkongensis. ..
  5. Qu F, Xiang Z, Li J, Xiao S, Mao F, Qin Y, et al. A molluscan extracellular signal-regulated kinase is involved in host response to immune challenges in vivo and in vitro. Fish Shellfish Immunol. 2017;62:311-319 pubmed publisher
    ..Moreover, ChERK was mainly located in the cytoplasm of HEK293T cells. Taken together, these findings may provide novel insights into the functions of molluscan ERKs, especially their roles in response to immune challenge in oyster. ..
  6. Qu F, Xiang Z, Zhang Y, Li J, Xiao S, Zhang Y, et al. Molecular identification and functional characterization of a tumor necrosis factor (TNF) gene in Crassostrea hongkongensis. Immunobiology. 2017;222:751-758 pubmed publisher
    ..Altogether, these findings may provide valuable information regarding oyster TNFs and its role in innate immunity. ..