Lin Feng

Summary

Affiliation: Sichuan Agricultural University
Country: China

Publications

  1. Jiang W, Zhou X, Zhang L, Liu Y, Wu P, Jiang J, et al. Vitamin A deficiency impairs intestinal physical barrier function of fish. Fish Shellfish Immunol. 2019;87:546-558 pubmed publisher
    ..Based on protecting fish against protein oxidation, the optimal VA levels for grass carp were estimated to be 2622 IU/kg diet. ..
  2. Wei S, Jiang W, Wu P, Liu Y, Zeng Y, Jiang J, et al. Dietary magnesium deficiency impaired intestinal structural integrity in grass carp (Ctenopharyngodon idella). Sci Rep. 2018;8:12705 pubmed publisher
    ..38, 839.86, 856.79 and 811.49 mg/kg, respectively. ..
  3. Jiang W, Tang R, Liu Y, Kuang S, Jiang J, Wu P, et al. Manganese deficiency or excess caused the depression of intestinal immunity, induction of inflammation and dysfunction of the intestinal physical barrier, as regulated by NF-κB, TOR and Nrf2 signalling, in grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2015;46:406-16 pubmed publisher
    ..90 and 8.99 mg kg(-1) diet, respectively. ..
  4. Jiang W, Liu Y, Jiang J, Wu P, Feng L, Zhou X. Copper exposure induces toxicity to the antioxidant system via the destruction of Nrf2/ARE signaling and caspase-3-regulated DNA damage in fish muscle: amelioration by myo-inositol. Aquat Toxicol. 2015;159:245-55 pubmed publisher
    ..Finally, MI protects fish against Cu toxicity. ..
  5. Liu H, Zhou X, Jiang W, Wu P, Liu Y, Zeng Y, et al. Optimal α-lipoic acid strengthen immunity of young grass carp (Ctenopharyngodon idella) by enhancing immune function of head kidney, spleen and skin. Fish Shellfish Immunol. 2018;80:600-617 pubmed publisher
    ..37, 382.33, 353.19 and 318.26 mg kg-1 diet, respectively. ..
  6. Huang C, Wu P, Jiang W, Liu Y, Zeng Y, Jiang J, et al. Deoxynivalenol decreased the growth performance and impaired intestinal physical barrier in juvenile grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2018;80:376-391 pubmed publisher
    ..Finally, based on PWG, FE, PC and MDA, the safe dose of DON for grass carp were all estimated to be 318 μg/kg diet. ..
  7. Chen G, Liu Y, Jiang J, Jiang W, Kuang S, Tang L, et al. Effect of dietary arginine on the immune response and gene expression in head kidney and spleen following infection of Jian carp with Aeromonas hydrophila. Fish Shellfish Immunol. 2015;44:195-202 pubmed publisher
    ..Our results indicate that arginine has beneficial effects on regulating mRNA expression of inflammatory cytokines, as well as TOR and 4E-BP and improving humoral and cellular immunity, therefore enhancing disease resistance of fish. ..
  8. Jiang W, Wen H, Liu Y, Jiang J, Kuang S, Wu P, et al. The tight junction protein transcript abundance changes and oxidative damage by tryptophan deficiency or excess are related to the modulation of the signalling molecules, NF-κB p65, TOR, caspase-(3,8,9) and Nrf2 mRNA levels, in the gill of young gras. Fish Shellfish Immunol. 2015;46:168-80 pubmed publisher
  9. Chen K, Zhou X, Jiang W, Wu P, Liu Y, Jiang J, et al. Impaired intestinal immune barrier and physical barrier function by phosphorus deficiency: Regulation of TOR, NF-?B, MLCK, JNK and Nrf2 signalling in grass carp (Ctenopharyngodon idella) after infection with Aeromonas hydrophila. Fish Shellfish Immunol. 2018;74:175-189 pubmed publisher
    ..Finally, based on the ability to combat enteritis, dietary available phosphorus requirement for grass carp (254.56-898.23?g) was estimated to be 4.68?g/kg diet. ..

More Information

Publications32

  1. Zeng Y, Jiang W, Liu Y, Wu P, Zhao J, Jiang J, et al. Dietary alpha-linolenic acid/linoleic acid ratios modulate intestinal immunity, tight junctions, anti-oxidant status and mRNA levels of NF-κB p65, MLCK and Nrf2 in juvenile grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2016;51:351-364 pubmed publisher
    ..78-72.00 g) were estimated to be 1.13 and 1.12, respectively. ..
  2. Jiang W, Hu K, Liu Y, Jiang J, Wu P, Zhao J, et al. Dietary myo-inositol modulates immunity through antioxidant activity and the Nrf2 and E2F4/cyclin signalling factors in the head kidney and spleen following infection of juvenile fish with Aeromonas hydrophila. Fish Shellfish Immunol. 2016;49:374-86 pubmed publisher
    ..Finally, the optimal MI levels were 660.7 (based on ACP) and 736.8 mg kg(-1) diet (based on MDA) in the head kidney and 770.5 (based on ACP) and 766.9 mg kg(-1) diet (based on MDA) in the spleen of juvenile Jian carp. ..
  3. Li H, Jiang W, Liu Y, Jiang J, Zhang Y, Wu P, et al. The metabolites of glutamine prevent hydroxyl radical-induced apoptosis through inhibiting mitochondria and calcium ion involved pathways in fish erythrocytes. Free Radic Biol Med. 2016;92:126-140 pubmed publisher
  4. Zhao H, Jiang W, Liu Y, Jiang J, Wu P, Kuang S, et al. Dietary choline regulates antibacterial activity, inflammatory response and barrier function in the gills of grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2016;52:139-50 pubmed publisher
    ..Based on gill C3 content and AHR activity, the dietary choline requirements for young grass carp (266.5-787.1 g) were estimated to be 1191.0 and 1555.0 mg/kg diet, respectively. ..
  5. Xu J, Wu P, Jiang W, Liu Y, Jiang J, Kuang S, et al. Optimal dietary protein level improved growth, disease resistance, intestinal immune and physical barrier function of young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2016;55:64-87 pubmed publisher
    ..82 g kg(-1) diet (250.66 g digestible protein kg(-1) diet) and 292.10 g kg(-1) diet (255.47 g digestible protein kg(-1) diet), respectively. ..
  6. Chen Y, Jiang W, Liu Y, Jiang J, Wu P, Zhao J, et al. Exogenous phospholipids supplementation improves growth and modulates immune response and physical barrier referring to NF-κB, TOR, MLCK and Nrf2 signaling factors in the intestine of juvenile grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2015;47:46-62 pubmed publisher
    ..34-87.50 g) were estimated to be 3.46%, 3.79%, 3.93%, 3.72%, and 4.12%, respectively. ..
  7. Wen L, Jiang W, Liu Y, Wu P, Zhao J, Jiang J, et al. Evaluation the effect of thiamin deficiency on intestinal immunity of young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2015;46:501-15 pubmed publisher
    ..The dietary thiamin requirement of young grass carp (242-742 g) based on intestinal LA activity or PWG were determined to be 1.15 or 0.90 mg/kg diet, respectively. ..
  8. Guo Y, Wu P, Jiang W, Liu Y, Kuang S, Jiang J, et al. The impaired immune function and structural integrity by dietary iron deficiency or excess in gill of fish after infection with Flavobacterium columnare: Regulation of NF-?B, TOR, JNK, p38MAPK, Nrf2 and MLCK signalling. Fish Shellfish Immunol. 2018;74:593-608 pubmed publisher
    ..Finally, the iron requirements based on ability against gill rot, ACP activity and MDA content in gill of young grass carp were estimated to be 76.52, 80.43 and 83.17?mg/kg, respectively. ..
  9. Wu P, Zheng X, Zhou X, Jiang W, Liu Y, Jiang J, et al. Deficiency of dietary pyridoxine disturbed the intestinal physical barrier function of young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2018;74:459-473 pubmed publisher
    ..Additionally, based on the quadratic regression analysis for MDA content and GST activity, the dietary PN requirements for young grass carp were estimated as 4.85 and 5.02?mg/kg diet, respectively. ..
  10. Jiang W, Wen H, Liu Y, Jiang J, Wu P, Zhao J, et al. Enhanced muscle nutrient content and flesh quality, resulting from tryptophan, is associated with anti-oxidative damage referred to the Nrf2 and TOR signalling factors in young grass carp (Ctenopharyngodon idella): Avoid tryptophan deficiency or exce. Food Chem. 2016;199:210-9 pubmed publisher
    ..Collectively, the present study indicated that appropriate Trp levels improved flesh quality partly related to the enhancement of antioxidant ability through Nrf2 and TOR signalling. ..
  11. Ni P, Jiang W, Wu P, Liu Y, Kuang S, Tang L, et al. Dietary low or excess levels of lipids reduced growth performance, and impaired immune function and structure of head kidney, spleen and skin in young grass carp (Ctenopharyngodon idella) under the infection of Aeromonas hydrophila. Fish Shellfish Immunol. 2016;55:28-47 pubmed publisher
    ..Based on the quadratic regression analysis for PWG, skin haemorrhage and lesions morbidity and IgM content, the dietary lipids requirements for young grass carp were estimated to be 43.7, 60.2, 55.0 and 52.1 g/kg diet, respectively. ..
  12. Wu P, Jiang W, Liu Y, Chen G, Jiang J, Li S, et al. Effect of choline on antioxidant defenses and gene expressions of Nrf2 signaling molecule in the spleen and head kidney of juvenile Jian carp (Cyprinus carpio var. Jian). Fish Shellfish Immunol. 2014;38:374-82 pubmed publisher
    ..In conclusion, dietary choline decreased the oxidant damage and regulated the antioxidant system in immune organs of juvenile Jian carp. ..
  13. Jiang W, Deng Y, Zhou X, Liu Y, Jiang J, Kuang S, et al. Towards the modulation of oxidative damage, apoptosis and tight junction protein in response to dietary leucine deficiency: A likely cause of ROS-induced gill structural integrity impairment. Fish Shellfish Immunol. 2017;70:609-620 pubmed publisher
  14. Song Z, Jiang W, Liu Y, Wu P, Jiang J, Zhou X, et al. Dietary zinc deficiency reduced growth performance, intestinal immune and physical barrier functions related to NF-?B, TOR, Nrf2, JNK and MLCK signaling pathway of young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2017;66:497-523 pubmed publisher
    ..Finally, based on specific growth rate (SGR), feed efficiency (FE) and against enteritis morbidity of young grass carp, the efficacy of zinc lactate relative to zinc sulfate were 132.59%, 135.27% and 154.04%, respectively. ..
  15. Jiang W, Tang R, Liu Y, Wu P, Kuang S, Jiang J, et al. Impairment of gill structural integrity by manganese deficiency or excess related to induction of oxidative damage, apoptosis and dysfunction of the physical barrier as regulated by NF-?B, caspase and Nrf2 signaling in fish. Fish Shellfish Immunol. 2017;70:280-292 pubmed publisher
  16. Jiang W, Xu J, Zhou X, Wu P, Liu Y, Jiang J, et al. Dietary protein levels regulated antibacterial activity, inflammatory response and structural integrity in the head kidney, spleen and skin of grass carp (Ctenopharyngodon idella) after challenged with Aeromonas hydrophila. Fish Shellfish Immunol. 2017;68:154-172 pubmed publisher
    ..68 g digestible protein kg-1 diet), 301.68 g kg-1 diet (265.48 g digestible protein kg-1 diet) and 307.84 g kg-1 diet (272.71 g digestible protein kg-1 diet), respectively. ..
  17. Wu P, Tian L, Zhou X, Jiang W, Liu Y, Jiang J, et al. Sodium butyrate enhanced physical barrier function referring to Nrf2, JNK and MLCK signaling pathways in the intestine of young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2018;73:121-132 pubmed publisher
    ..Finally, based on protein carbonyl content in the PI, the optimal SB supplementation (MSB as SB source) for young grass carp was estimated to be 338.8 mg kg-1 diet. ..
  18. Tian L, Zhou X, Jiang W, Liu Y, Wu P, Jiang J, et al. Sodium butyrate improved intestinal immune function associated with NF-?B and p38MAPK signalling pathways in young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2017;66:548-563 pubmed publisher
    ..8, 339.9 and 316.2 mg kg-1 diet, respectively. ..
  19. Jiang W, Wu P, Tang R, Liu Y, Kuang S, Jiang J, et al. Nutritive values, flavor amino acids, healthcare fatty acids and flesh quality improved by manganese referring to up-regulating the antioxidant capacity and signaling molecules TOR and Nrf2 in the muscle of fish. Food Res Int. 2016;89:670-678 pubmed publisher
    ..We firstly demonstrated that Mn improved flesh quality, flavor and healthcare function in fish muscle. ..
  20. Guo Y, Jiang W, Wu P, Liu Y, Zhou X, Kuang S, et al. The decreased growth performance and impaired immune function and structural integrity by dietary iron deficiency or excess are associated with TOR, NF-?B, p38MAPK, Nrf2 and MLCK signaling in head kidney, spleen and skin of grass carp (Ctenopharyngod. Fish Shellfish Immunol. 2017;65:145-168 pubmed publisher
    ..65, 87.03, 79.74, 78.93, 83.17 and 82.14 mg/kg diet (based on ferrous fumarate), respectively. ..
  21. Wu P, Liu Y, Jiang W, Jiang J, Zhang Y, Zhou X, et al. Intestinal immune responses of Jian carp against Aeromonas hydrophila depressed by choline deficiency: Varied change patterns of mRNA levels of cytokines, tight junction proteins and related signaling molecules among three intestinal segments. Fish Shellfish Immunol. 2017;65:34-41 pubmed publisher
    ..This study provides new finding that choline deficiency-induced immune responses against A. hydrophila infection were varied among three intestinal segments in fish. ..
  22. Chen K, Jiang W, Wu P, Liu Y, Kuang S, Tang L, et al. Effect of dietary phosphorus deficiency on the growth, immune function and structural integrity of head kidney, spleen and skin in young grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2017;63:103-126 pubmed publisher
    ..10 and 4.13 g/kg diet, respectively. In summary, phosphorus deficiency decreases the growth performance, and impairs immune function and structural integrity in the head kidney, spleen and skin of young grass carp. ..
  23. Wu P, Jiang W, Jiang J, Zhao J, Liu Y, Zhang Y, et al. Dietary choline deficiency and excess induced intestinal inflammation and alteration of intestinal tight junction protein transcription potentially by modulating NF-?B, STAT and p38 MAPK signaling molecules in juvenile Jian carp. Fish Shellfish Immunol. 2016;58:462-473 pubmed publisher
    ..In summary, dietary choline deficiency or excess caused the depression of intestinal mucosal immune by inducing inflammation and dysfunction of the intestinal physical barrier, and regulating related signaling molecules of fish. ..