Hua hao Shen

Summary

Country: China

Publications

  1. pmc Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B
    Feng Xu
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, China
    Respir Res 9:16. 2008
  2. doi request reprint Astragalus Membranaceus prevents airway hyperreactivity in mice related to Th2 response inhibition
    Hua hao Shen
    Department of Respiratory Medicine, The Second Affiliated Hospital, Medical School of Zhejiang University, 88 Jiefang Road, Hangzhou 310009, China
    J Ethnopharmacol 116:363-9. 2008
  3. ncbi request reprint Inhibitory effect of acetamide-45 on airway inflammation and phosphodiesterase 4 in allergic rats
    Kai Wang
    Respiratory Department, Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou 310009, China
    Acta Pharmacol Sin 26:1492-6. 2005
  4. ncbi request reprint CCR3 monoclonal antibody inhibits airway eosinophilic inflammation and mucus overproduction in a mouse model of asthma
    Hua hao Shen
    Department of Respiratory Diseases, The Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, China
    Acta Pharmacol Sin 27:1594-9. 2006
  5. ncbi request reprint [The preventive effect of bacillus Calmette-Guerin vaccination in early life on airway inflammation and mucus production in a murine model of asthma]
    Gen Sheng Zhang
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine Institute of Respiratory Medicine, Hangzhou 310009, China
    Zhonghua Jie He He Hu Xi Za Zhi 28:17-21. 2005
  6. doi request reprint Acetamide-45 inhibited hyperresponsiveness and airway inflammation in mice partly depending on phosphodiesterase activity suppression
    Kai Wang
    Department of Respiratory Medicine, Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou 310009, China
    Acta Pharmacol Sin 29:1195-201. 2008
  7. ncbi request reprint Effects of CpG oligodeoxynucleotide on transcription factors GATA-3 and T-bet mRNA expression in asthmatic mice
    Zu qun Wu
    Department of Respiratory Medicine, The Second Affiliated Hospital, 4Department of Pathology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    Acta Pharmacol Sin 26:1117-22. 2005
  8. ncbi request reprint Mycobacterium bovis-Bacillus Calmette-Guerin and asthma
    Hua hao Shen
    Department of Respiratory Medicine, Second Hospital of Zhejiang University Medical College Hangzhou 310009, China
    Chin Med J (Engl) 118:942-7. 2005
  9. ncbi request reprint Human C-C chemokine receptor 3 monoclonal antibody inhibits pulmonary inflammation in allergic mice
    Kai Wang
    Department of Respiratory Medicine, The Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou 310009, China
    Acta Pharmacol Sin 28:1791-6. 2007
  10. doi request reprint Neonatal bacillus Calmette-Guérin vaccination inhibits de novo allergic inflammatory response in mice via alteration of CD4+CD25+ T-regulatory cells
    Qian Li
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, China
    Acta Pharmacol Sin 30:125-33. 2009

Collaborators

Detail Information

Publications29

  1. pmc Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B
    Feng Xu
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, China
    Respir Res 9:16. 2008
    ....
  2. doi request reprint Astragalus Membranaceus prevents airway hyperreactivity in mice related to Th2 response inhibition
    Hua hao Shen
    Department of Respiratory Medicine, The Second Affiliated Hospital, Medical School of Zhejiang University, 88 Jiefang Road, Hangzhou 310009, China
    J Ethnopharmacol 116:363-9. 2008
    ..The purpose of this study is to determine whether this herbal injection could suppress allergic-induced AHR and mucus hypersecretion in allergic mice...
  3. ncbi request reprint Inhibitory effect of acetamide-45 on airway inflammation and phosphodiesterase 4 in allergic rats
    Kai Wang
    Respiratory Department, Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou 310009, China
    Acta Pharmacol Sin 26:1492-6. 2005
    ..To determine the effects of acetamide-45 on respiratory function, airway inflammation, and the activity of phosphodiesterase 4 (PDE4) in allergic rats...
  4. ncbi request reprint CCR3 monoclonal antibody inhibits airway eosinophilic inflammation and mucus overproduction in a mouse model of asthma
    Hua hao Shen
    Department of Respiratory Diseases, The Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, China
    Acta Pharmacol Sin 27:1594-9. 2006
    ..To explore the effect of a rat anti-mouse CC-chemokine receptor-3 (CCR3) monoclonal antibody (CCR3 mAb) on airway eosinophilia and mucus overproduction in asthmatic mice...
  5. ncbi request reprint [The preventive effect of bacillus Calmette-Guerin vaccination in early life on airway inflammation and mucus production in a murine model of asthma]
    Gen Sheng Zhang
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine Institute of Respiratory Medicine, Hangzhou 310009, China
    Zhonghua Jie He He Hu Xi Za Zhi 28:17-21. 2005
    ..To investigate the preventive effect of bacillus Calmette-Guerin (BCG) vaccination in early life on airway inflammation and mucus production in a murine model of asthma...
  6. doi request reprint Acetamide-45 inhibited hyperresponsiveness and airway inflammation in mice partly depending on phosphodiesterase activity suppression
    Kai Wang
    Department of Respiratory Medicine, Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou 310009, China
    Acta Pharmacol Sin 29:1195-201. 2008
    ..The purpose of this study is to determine whether this agent could suppress allergic-induced airway hyperresponsiveness (AHR) and airway inflammation in allergic mice...
  7. ncbi request reprint Effects of CpG oligodeoxynucleotide on transcription factors GATA-3 and T-bet mRNA expression in asthmatic mice
    Zu qun Wu
    Department of Respiratory Medicine, The Second Affiliated Hospital, 4Department of Pathology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    Acta Pharmacol Sin 26:1117-22. 2005
    ..To investigate effects of CpG oligodeoxynucleotide (CpG ODN) on the mRNA expression of transcription factors GATA binding protein 3 (GATA-3) and T-box expressed in T cells (T-bet) in asthmatic mice...
  8. ncbi request reprint Mycobacterium bovis-Bacillus Calmette-Guerin and asthma
    Hua hao Shen
    Department of Respiratory Medicine, Second Hospital of Zhejiang University Medical College Hangzhou 310009, China
    Chin Med J (Engl) 118:942-7. 2005
  9. ncbi request reprint Human C-C chemokine receptor 3 monoclonal antibody inhibits pulmonary inflammation in allergic mice
    Kai Wang
    Department of Respiratory Medicine, The Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou 310009, China
    Acta Pharmacol Sin 28:1791-6. 2007
    ..To evaluate the effect of C-C chemokine receptor 3 (CCR3) blockade on pulmonary inflammation and mucus production in allergic mice...
  10. doi request reprint Neonatal bacillus Calmette-Guérin vaccination inhibits de novo allergic inflammatory response in mice via alteration of CD4+CD25+ T-regulatory cells
    Qian Li
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, China
    Acta Pharmacol Sin 30:125-33. 2009
    ....
  11. ncbi request reprint CD69 expression on airway eosinophils and airway inflammation in a murine model of asthma
    Hui Ying Wang
    Department of Respiratory Medicine, Second Affiliated Hospital of Zhejiang University Medical College, Institute of Respiratory Diseases of Zhejiang University, Hangzhou, China
    Chin Med J (Engl) 119:1983-90. 2006
    ..We investigated the expression of CD69 on murine eosinophils in vitro, the relationship between the expression of CD69 on eosinophils from peripheral blood and bronchoalveolar lavage fluid and on airway inflammation in asthmatic mice...
  12. doi request reprint Effect of Astragali-Cordyceps Mixtura on TGF-beta/Smad signal pathway in the lung of asthma airway remodeling
    Gui xin Gao
    Department of Respiratory Medicine, Second Hospital of Medical School of Zhejiang University, Institute of Respiratory Diseases, Zhejiang University, 88 Jiefang Road, Hangzhou 310009, China
    J Ethnopharmacol 125:68-74. 2009
    ..We try to find out the influence of traditional Chinese Medicine Astragali-Cordyceps Mixtura (ACM) on TGF-beta/Smad signal pathway in the lung of asthma airway remodeling...
  13. ncbi request reprint Effect of cigarette smoke extract on lipopolysaccha-ride-activated mitogen-activated protein kinase signal transduction pathway in cultured cells
    Wen Li
    Department of Respiratory Medicine, Second Affiliated Hospital, College of Medicine and Institute of Respiratory Diseases, Zhejiang University, Hangzhou 310009, China
    Chin Med J (Engl) 120:1075-81. 2007
    ..This study was designed to examine the effects of cigarette smoke extract (CSE) and LPS on MAPK signal transduction pathway in order to further understand the roles CSE and LPS play in chronic lung inflammation...
  14. ncbi request reprint Effect of respiratory syncytial virus on the activity of matrix metalloproteinase in mice
    Wen Li
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University College of Medicine, Institute of Respiratory Diseases Zhejiang University, Hangzhou 310009, China
    Chin Med J (Engl) 120:5-11. 2007
    ..This study was undertaken to examine the effect of infection with RSV on matrix metalloproteinase (MMPs) in mice, and to explore the role of RSV in the pathogenesis of pulmonary diseases...
  15. ncbi request reprint [An analysis of the survey data on Hangzhou community physicians' perceptions of asthma knowledge and management]
    Ping Li Wang
    Department of Respiratory Disease, The Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, China
    Zhonghua Jie He He Hu Xi Za Zhi 32:270-3. 2009
    ..To evaluate the basic knowledge of asthma, the standardization of treatment and the continuing education with community physicians in Hangzhou...
  16. ncbi request reprint Airborne fine particulate matter induced pulmonary inflammation as well as oxidative stress in neonate rats
    Li ren Ding
    Department of Respiratory Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
    Chin Med J (Engl) 123:2895-900. 2010
    ..This study aimed to observe the potential impact and toxicity of fine PMs on the airway in neonate rats...
  17. ncbi request reprint [The role of p38 mitogen activated protein kinase in the inflammatory response of human monocytes infected with nontypeable Haemophilus influenzae]
    Zhi hao Xu
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Zhonghua Jie He He Hu Xi Za Zhi 31:348-51. 2008
    ..To investigate the role of mitogen activated protein kinase (MAPK) pathway in the inflammatory response induced by nontypeable Haemophilus influenzae (NTHi)...
  18. ncbi request reprint [cAMP response element binding protein expression and activity in acute lung injury induced by endotoxinemia following hemorrhagic shock: experiment with rabbits]
    Qian Li
    Department of Respiratory Medicine, Second Hospital, Medical College of Zhejiang University, Hangzhou 310009, China
    Zhonghua Yi Xue Za Zhi 87:2791-5. 2007
    ..To investigate the cAMP response element binding protein (CREB) expression and activity in acute lung injury induced by endotoxinemia following hemorrhagic shock...
  19. ncbi request reprint Pulmonary alveolar microlithiasis: report of four familial cases
    Hui Ying Wang
    Department of Respiratory Medicine, Second Affiliated Hospital corrected Zhejiang University Medical School, Hangzhou 310009, China
    Chin Med J (Engl) 117:950-2. 2004
  20. pmc The diagnostic significance of the detection of cytokeratin 19 mRNA by quantitative RT-PCR in benign and malignant pleural effusions
    Feng Xu
    Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci 5:1286-9. 2004
    ..To evaluate the diagnostic significance of detecting cytokeratin 19 (CK19) mRNA by quantitative reverse transcription polymerase chain reaction (RT-PCR) in benign and malignant pleural effusions...
  21. ncbi request reprint [The expression of transforming growth factor beta-1 in rat model of chronic obstructive pulmonary disease and the effects of early drugs intervention]
    Ding qian Wu
    Department of Respiratory Medicine, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 33:427-32, 448. 2004
    ..To evaluate the expression of transforming growth factor beta-1(TGF-beta1) and the effects of early drugs intervention of chronic obstructive pulmonary disease(COPD) in rat model...
  22. ncbi request reprint Primary choriocarcinoma in the anterior mediastinum in a man: a case report and review of the literatures
    Hua hao Shen
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
    Chin Med J (Engl) 117:1743-5. 2004
  23. pmc Imbalanced expression of mitogen-activated protein kinase phosphatase-1 and phosphorylated extracellular signal-regulated kinases in lung squamous cell carcinoma
    Kai Wang
    Department of Respiratory Medicine, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    J Zhejiang Univ Sci B 12:828-34. 2011
    ....
  24. ncbi request reprint [Relationship between measurements of tidal volume and thoracic inflating volume by pressure plethysmography in mice]
    Wu jun Hong
    Department of Pulmonology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 37:257-60. 2008
    ..To evaluate the accordance of tidal volume (TV) with thoracic inflating volume (TIV) measured by pressure whole-body or double-chamber plethysmography in mice...
  25. ncbi request reprint [Effects of budesonide on airway inflammation and airway remodeling in the ovalbumin sensitized and challenged mice]
    Hua hao Shen
    Department of Respiratory Medicine, Second Hospital, Medical College of Zhejiang University, Zhejiang University Institute of Respiratory Diseases, Hangzhou 310009, China
    Zhonghua Jie He He Hu Xi Za Zhi 28:154-9. 2005
    ..To investigate the effects of budesonide (BUD) used in an early phase or delayed phase on the airway inflammation and airway remodeling in ovalbumin (OVA) sensitized and challenged mice...
  26. ncbi request reprint The dynamic changes of LDH isoenzyme 3 and D-dimer following pulmonary thromboembolism in canine
    Su qin Ben
    Department of Respiratory Medicine, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Road, Hangzhou, China
    Thromb Res 120:575-83. 2007
    ..To investigate the time course of changes of lactic acid dehydrogenase (LDH), LDH isoenzymes and D-dimer levels following acute pulmonary thromboembolism (PTE)...
  27. ncbi request reprint Adenoid cystic carcinoma of trachea: a case report and review of literature
    Wen Li
    Department of Respiratory Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, China
    Chin Med J (Engl) 125:2238-9. 2012
    ..In addition, we reviewed the literature of primary tracheal tumors and summarized the epidemiology, presenting features, available therapeutic options of the disease...
  28. ncbi request reprint Validity of Asthma Control Test in Chinese patients
    Xin Zhou
    Department of Respiratory Medicine, Shanghai First People s Hospital, Shanghai Jiao Tong University, Shanghai 200080, China
    Chin Med J (Engl) 120:1037-41. 2007
    ..So far, in China, there has been no effective or easy procedure to define the control of asthma. This study assesses the validity of Asthma Control Test in Chinese patients...
  29. pmc A case of chylothorax treated curatively with Sapylin, a streptococcus preparation
    Zhi hao Xu
    Department of Respiratory Diseases, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    J Zhejiang Univ Sci B 8:885-7. 2007
    ..Two-time intra-thoracic injection of 3 Klinische Einheit (KE) Sapylin achieved rapid and effective control of chylothorax with no severe side effects. Sapylin may facilitate pleurodesis by producing a strong inflammatory response...