Yuejun Fu

Summary

Affiliation: Shanxi University
Country: China

Publications

  1. doi Potential adenovirus-mediated gene therapy of glioma cancer
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, 030006, Taiyuan, People s Republic of China
    Biotechnol Lett 32:11-8. 2010
  2. doi Glioma derived isocitrate dehydrogenase-2 mutations induced up-regulation of HIF-1α and β-catenin signaling: possible impact on glioma cell metastasis and chemo-resistance
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Int J Biochem Cell Biol 44:770-5. 2012
  3. doi Chlorotoxin-conjugated nanoparticles as potential glioma-targeted drugs
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    J Neurooncol 107:457-62. 2012
  4. doi Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    Biotechnol Lett 34:441-6. 2012
  5. doi Recombinant scorpion insect excitatory toxin BmK IT accelerates the growth of insect Spodoptera frugiperda 9 cells
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    Mol Cell Biochem 351:93-8. 2011
  6. doi β-catenin as a potential key target for tumor suppression
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, People s Republic of China
    Int J Cancer 129:1541-51. 2011
  7. doi Glioma-derived mutations in IDH: from mechanism to potential therapy
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Biochem Biophys Res Commun 397:127-30. 2010
  8. doi Glioma-derived mutations in isocitrate dehydrogenase 2 beneficial to traditional chemotherapy
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Biochem Biophys Res Commun 410:218-23. 2011
  9. doi A potential strategy for high-grade gliomas: combination treatment with lithium chloride and BmK CT
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 34:9-17. 2012
  10. doi A model of BmK CT in inhibiting glioma cell migration via matrix metalloproteinase-2 from experimental and molecular dynamics simulation study
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, People s Republic of China
    Biotechnol Lett 33:1309-17. 2011

Collaborators

Detail Information

Publications17

  1. doi Potential adenovirus-mediated gene therapy of glioma cancer
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, 030006, Taiyuan, People s Republic of China
    Biotechnol Lett 32:11-8. 2010
    ....
  2. doi Glioma derived isocitrate dehydrogenase-2 mutations induced up-regulation of HIF-1α and β-catenin signaling: possible impact on glioma cell metastasis and chemo-resistance
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Int J Biochem Cell Biol 44:770-5. 2012
    ..These results demonstrated a functional model in which IDH mutations were closely interrelated with glioma progression and could hold some therapeutic implications for future human glioma treatment...
  3. doi Chlorotoxin-conjugated nanoparticles as potential glioma-targeted drugs
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    J Neurooncol 107:457-62. 2012
    ..We review the latest improvements of CTX-modified nanoparticle platforms which might enable development of more effective therapeutic agents in clinical treatment of glioma...
  4. doi Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    Biotechnol Lett 34:441-6. 2012
    ..The HIF-1α pathway is probably a critical pathway for release of MMPs in the glioma cancer harboring IDH mutant...
  5. doi Recombinant scorpion insect excitatory toxin BmK IT accelerates the growth of insect Spodoptera frugiperda 9 cells
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    Mol Cell Biochem 351:93-8. 2011
    ..The findings presented in this study are essential for further study of this peptide...
  6. doi β-catenin as a potential key target for tumor suppression
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, People s Republic of China
    Int J Cancer 129:1541-51. 2011
    ....
  7. doi Glioma-derived mutations in IDH: from mechanism to potential therapy
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Biochem Biophys Res Commun 397:127-30. 2010
    ....
  8. doi Glioma-derived mutations in isocitrate dehydrogenase 2 beneficial to traditional chemotherapy
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Biochem Biophys Res Commun 410:218-23. 2011
    ....
  9. doi A potential strategy for high-grade gliomas: combination treatment with lithium chloride and BmK CT
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 34:9-17. 2012
    ..Our results suggested that the combination treatment of lithium and BmK CT may constitute a novel and potential strategy for HHG therapy...
  10. doi A model of BmK CT in inhibiting glioma cell migration via matrix metalloproteinase-2 from experimental and molecular dynamics simulation study
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, People s Republic of China
    Biotechnol Lett 33:1309-17. 2011
    ..This is the first documentation of the structural mechanism of in the inhibition of glioma cell migration by BmK CT and may lead to the molecular design of specific inhibitors of MMP-2...
  11. doi Adenovirus-mediated expression of BmK CT suppresses growth and invasion of rat C6 glioma cells
    Jun Du
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 35:861-70. 2013
    ..The adenovirus-mediated expression of BmK CT displayed a high activity in suppressing rat C6 glioma cells growth and invasion thereby suggesting that this recombinant adenovirus may be a powerful method for treating glioblastoma...
  12. ncbi Synthesis, expression and purification of a type of chlorotoxin-like peptide from the scorpion, Buthus martensii Karsch, and its acute toxicity analysis
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, 030006, Taiyuan, People s Republic of China
    Biotechnol Lett 27:1597-603. 2005
    ..Western blot analysis demonstrated that this protein was rBmK CTa. Acute toxicity assay in mice demonstrated that the rBmK CTa had an LD(50) value of 4.3 mg kg(-1)...
  13. ncbi Interaction of two classes of release factors from Euplotes octocarinatus
    Bao Feng Chai
    Key Laboratory of Chemical Biology and Molecular Engineering of Education Ministry, Shanxi University, Taiyuan 030006, China
    Yi Chuan Xue Bao 31:460-7. 2004
    ..Two classes of RFs are useful information in analysis of evolution of life-form and further elucidation of mechanism of translation termination of protein synthesis on ribosome...
  14. doi Effect of location of the His-tag on the production of soluble and functional Buthus martensii Karsch insect toxin
    Cheng Gang Xu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Wucheng Road 36, Taiyuan, Shanxi 030006, PR China
    Protein Expr Purif 59:103-9. 2008
    ..This result indicated that the positioning of the His(6) tag has a key role in the production of soluble and functional BmK IT...
  15. ncbi [Soluble expression, purification and characterization of Bm K IT in Escherichia coli by intein-mediated system]
    Cheng Gang Xu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, China
    Sheng Wu Gong Cheng Xue Bao 23:989-94. 2007
    ..BmK IT(his6) was purified through Superdex 75 gel chromatography to more than 95% homogeneity. The purified protein has both correct secondary structure and insecticidal activity...
  16. ncbi Potential biochemical therapy of glioma cancer
    Li Tian Yin
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Biochem Biophys Res Commun 362:225-9. 2007
    ..These new findings may represent future directions for brain tumor studies and treatment...
  17. ncbi Therapeutic potential of chlorotoxin-like neurotoxin from the Chinese scorpion for human gliomas
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Neurosci Lett 412:62-7. 2007
    ..These results suggest that rBmK CTa may have potential therapeutic application in clinical treatment of human glioma. It represents an approach for developing a novel therapeutic agent...