Affiliation: Shanghai Jiaotong University
Li P, Yang Q, Li S, Sun H, Liu H, Li B, et al
. Candidates for reproductive biomarkers: Protein phosphorylation and acetylation positively related to selected parameters of boar spermatozoa quality. Anim Reprod Sci. 2018;197:67-80 pubmed publisher
Yang Q, Li P, Wen Y, Li S, Chen J, Liu X, et al
. Cadmium inhibits lysine acetylation and succinylation inducing testicular injury of mouse during development. Toxicol Lett. 2018;291:112-120 pubmed publisher
..Our research may provide a new way to reveal the mechanisms of Cd reproductive toxicity related to lysine acetylation and succinylation. ..
Xinhong L, Zhen L, Fu J, Wang L, Yang Q, Li P, et al
. Quantitative proteomic profiling indicates the difference in reproductive efficiency between Meishan and Duroc boar spermatozoa. Theriogenology. 2018;116:71-82 pubmed publisher
..Taken together, the physiologically and functionally differential proteins may be one main reason for explaining the high reproductive efficiency of Meishan boar. ..
Wang L, Li Y, Fu J, Zhen L, Zhao N, Yang Q, et al
. Cadmium inhibits mouse sperm motility through inducing tyrosine phosphorylation in a specific subset of proteins. Reprod Toxicol. 2016;63:96-106 pubmed publisher
..These results suggest that Cd-induced tyrosine phosphorylation of 55-57KDa proteins might act as an engine to block intracellular energy metabolism and thus decrease sperm motility. ..
Li X, Wang L, Li Y, Fu J, Zhen L, Yang Q, et al
. Tyrosine phosphorylation of dihydrolipoamide dehydrogenase as a potential cadmium target and its inhibitory role in regulating mouse sperm motility. Toxicology. 2016;357-358:52-64 pubmed publisher
..This study provided new understanding of the mechanisms contributing to the harmful effects of Cd on the motility and function of spermatozoa. ..
Li X, Wang L, Li Y, Zhao N, Zhen L, Fu J, et al
. Calcium regulates motility and protein phosphorylation by changing cAMP and ATP concentrations in boar sperm in vitro. Anim Reprod Sci. 2016;172:39-51 pubmed publisher
..The present study provided some novel insights into the molecular mechanism underlying the effects of Ca(2+) on boar sperm as well as the involvement of energy metabolism in this mechanism. ..
Zhen L, Wang L, Fu J, Li Y, Zhao N, Li X. Hexavalent chromium affects sperm motility by influencing protein tyrosine phosphorylation in the midpiece of boar spermatozoa. Reprod Toxicol. 2016;59:66-79 pubmed publisher
..These results suggest that chromium affects boar sperm motility by impairing tyrosine phosphorylation in the midpiece of sperm by blocking the cAMP/PKA pathway in boar sperm in vitro. ..
Fu J, Li Y, Wang L, Zhen L, Yang Q, Li P, et al
. Bovine serum albumin and skim-milk improve boar sperm motility by enhancing energy metabolism and protein modifications during liquid storage at 17 °C. Theriogenology. 2017;102:87-97 pubmed publisher
Wang L, Li P, Wen Y, Yang Q, Zhen L, Fu J, et al
. Vitamin C exerts novel protective effects against cadmium toxicity in mouse spermatozoa by inducing the dephosphorylation of dihydrolipoamide dehydrogenase. Reprod Toxicol. 2018;75:23-32 pubmed publisher
..Hence, the protective effects of Vc on the tyrosine phosphorylation of DLD might be attributed to its binding to Cd ions outside or inside sperm, and were not due to its antioxidant properties. ..