Cheng Hu

Summary

Affiliation: Shanghai Jiaotong University
Country: China

Publications

  1. pmc Lack of association between genetic polymorphisms within DUSP12 - ATF6 locus and glucose metabolism related traits in a Chinese population
    Cheng Hu
    Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, PR China
    BMC Med Genet 12:3. 2011
  2. pmc Impact of marker density on the accuracy of association mapping
    Weihua Zhang
    Section of Cancer Genetics, The Institute of Cancer Research, 15 Cotswold Road, Belmont, Sutton, Surrey SM2 5NG, UK
    BMC Proc 1:S166. 2007
  3. pmc Association mapping of susceptibility loci for rheumatoid arthritis
    Tai Yue Kuo
    Human Genetics Division, Duthie Building Mailpoint 808, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
    BMC Proc 1:S15. 2007
  4. pmc An evaluation of the performance of HapMap SNP data in a Shanghai Chinese population: analyses of allele frequency, linkage disequilibrium pattern and tagging SNPs transferability on chromosome 1q21-q25
    Cheng Hu
    Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, 600 Yishan Road, Shanghai, 200233, China
    BMC Genet 9:19. 2008
  5. pmc Associations of common variants at APLN and hypertension in Chinese subjects with and without diabetes
    Rong Zhang
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, 600 Yishan Road Shanghai, 200233, China
    Exp Diabetes Res 2012:917496. 2012
  6. ncbi request reprint [Association of variants in APPL1 gene with body fat and its distribution in Chinese patients with type 2 diabetic mellitus]
    Qi chen Fang
    Shanghai Diabetes Institute, Shanghai Clinical Center of Diabetes, Department of Endocrinology and Metabolism, Sixth People s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 88:369-73. 2008
  7. pmc Variants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 are associated with glucose metabolism in the Chinese
    Cheng Hu
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, People s Republic of China
    PLoS ONE 5:e15542. 2010
  8. doi request reprint [No association of vascular endothelial growth factor A gene rs9369425 polymorphism with glucose metabolism in Chinese Han population]
    Rong Zhang
    Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai JiaoTong University Affiliated Sixth People s Hospital, Shanghai, 200233 PR China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27:457-9. 2010
  9. ncbi request reprint [Association of -6735T-->C variant of glucokinase-associated dual-specificity phosphatase 12 gene with type 2 diabetes in Chinese]
    Fei Gao
    Shanghai Clinical Medicine Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated No 6 People s Hospital, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 88:2250-3. 2008
  10. pmc Effects of GCK, GCKR, G6PC2 and MTNR1B variants on glucose metabolism and insulin secretion
    Cheng Hu
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, China
    PLoS ONE 5:e11761. 2010

Collaborators

Detail Information

Publications47

  1. pmc Lack of association between genetic polymorphisms within DUSP12 - ATF6 locus and glucose metabolism related traits in a Chinese population
    Cheng Hu
    Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, PR China
    BMC Med Genet 12:3. 2011
    ..Studies in Pima Indian, Caucasians and African Americans identified several SNPs in DUSP12 and ATF6, located in chromosome 1q21-q23, were associated with type 2 diabetes...
  2. pmc Impact of marker density on the accuracy of association mapping
    Weihua Zhang
    Section of Cancer Genetics, The Institute of Cancer Research, 15 Cotswold Road, Belmont, Sutton, Surrey SM2 5NG, UK
    BMC Proc 1:S166. 2007
    ..We also demonstrated that SNP selection based on equal LD distance outperforms that based on equal physical distance or SNP tagging. Furthermore, ignoring rare SNPs diminished the ability to detect rare causal variants...
  3. pmc Association mapping of susceptibility loci for rheumatoid arthritis
    Tai Yue Kuo
    Human Genetics Division, Duthie Building Mailpoint 808, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
    BMC Proc 1:S15. 2007
    ..SNP selection based on equal linkage disequilibrium (LD) distance generally produced higher accuracy than that based on equal kilobase distance or tagging...
  4. pmc An evaluation of the performance of HapMap SNP data in a Shanghai Chinese population: analyses of allele frequency, linkage disequilibrium pattern and tagging SNPs transferability on chromosome 1q21-q25
    Cheng Hu
    Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, 600 Yishan Road, Shanghai, 200233, China
    BMC Genet 9:19. 2008
    ....
  5. pmc Associations of common variants at APLN and hypertension in Chinese subjects with and without diabetes
    Rong Zhang
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, 600 Yishan Road Shanghai, 200233, China
    Exp Diabetes Res 2012:917496. 2012
    ..The aim of the study was to investigate the association between the common variants of apelin gene (APLN) and hypertension, which was reported recently in a Chinese Han population with and without diabetes...
  6. ncbi request reprint [Association of variants in APPL1 gene with body fat and its distribution in Chinese patients with type 2 diabetic mellitus]
    Qi chen Fang
    Shanghai Diabetes Institute, Shanghai Clinical Center of Diabetes, Department of Endocrinology and Metabolism, Sixth People s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 88:369-73. 2008
    ..To investigate the impact of single nucleotide polymorphisms (SNPs) in APPL1 gene on body fat and its distribution...
  7. pmc Variants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 are associated with glucose metabolism in the Chinese
    Cheng Hu
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, People s Republic of China
    PLoS ONE 5:e15542. 2010
    ..In the current study, we aimed to evaluate the association between these loci and traits related to glucose metabolism in the Chinese...
  8. doi request reprint [No association of vascular endothelial growth factor A gene rs9369425 polymorphism with glucose metabolism in Chinese Han population]
    Rong Zhang
    Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai JiaoTong University Affiliated Sixth People s Hospital, Shanghai, 200233 PR China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27:457-9. 2010
    ..To investigate the relationship between the vascular endothelial growth factor A gene (VEGFA) rs9369425 single nucleotide polymorphism (SNP) and type 2 diabetes in Chinese Han population...
  9. ncbi request reprint [Association of -6735T-->C variant of glucokinase-associated dual-specificity phosphatase 12 gene with type 2 diabetes in Chinese]
    Fei Gao
    Shanghai Clinical Medicine Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated No 6 People s Hospital, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 88:2250-3. 2008
    ..To investigate the impact of glucokinase-associated dual-specificity phosphatase 12 gene (DUSP12) single nucleotide polymorphism (SNP) on type 2 diabetes mellitus in Chinese...
  10. pmc Effects of GCK, GCKR, G6PC2 and MTNR1B variants on glucose metabolism and insulin secretion
    Cheng Hu
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, China
    PLoS ONE 5:e11761. 2010
    ..The current study aimed to replicate this association in the Chinese population and further analyze their effects on biphasic insulin secretion...
  11. ncbi request reprint [Relationship between adiponectin receptor 1 gene -3881T/C variant and glucose metabolism in the Chinese]
    Cheng Hu
    Shanghai Clinical Medicine Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated No 6 People s Hospital, Shanghai, 200233 PR China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 24:27-30. 2007
    ..To investigate the relationship between adiponectin receptor 1 gene (ADIPOR1) single nucleotide polymorphism (SNP) and glucose metabolism and insulin resistance in the Chinese...
  12. doi request reprint A common genetic variant of FCN3/CD164L2 is associated with essential hypertension in a Chinese population
    Jingyi Lu
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, PR China
    Clin Exp Hypertens 34:377-82. 2012
    ..We found that a common variant of FCN3/CD164L2 is associated with hypertension in our Chinese population. More studies with larger sample size are needed to confirm this finding...
  13. doi request reprint Association of a SLC30A8 genetic variant with monotherapy of repaglinide and rosiglitazone effect in newly diagnosed type 2 diabetes patients in China
    Feng Jiang
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, China
    Biomed Environ Sci 25:23-9. 2012
    ..To investigate a potential relationship between Solute carrier family 30 (zinc transporter) member 8 (SLC30A8) rs13266634 variant and efficacy of rosiglitazone or repaglinide in treating newly diagnosed Chinese type 2 diabetes patients...
  14. ncbi request reprint [Study on the status of metabolic syndrome in familial type 2 diabetes pedigrees]
    Xiao Jing Ma
    Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism of Shanghai Jiaotong University Affiliated Sixth People s Hospital, Shanghai 200233, China
    Zhonghua Liu Xing Bing Xue Za Zhi 29:745-8. 2008
    ..To investigate the prevalence of metabolic syndrome (MS) and its components in type 2 diabetes mellitus pedigrees...
  15. doi request reprint Effects of ABCA1 variants on rosiglitazone monotherapy in newly diagnosed type 2 diabetes patients
    Jie Wang
    Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai 200233, China
    Acta Pharmacol Sin 29:252-8. 2008
    ....
  16. pmc Common variants of hepatocyte nuclear factor 1beta are associated with type 2 diabetes in a Chinese population
    Congrong Wang
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai, China
    Diabetes 58:1023-7. 2009
    ..We therefore investigated common variants across the HNF1beta gene in a Chinese population...
  17. ncbi request reprint [The effect of single nucleotide polymorphism SNP + 45 of the adiponectin gene on the rosiglitazone maleate response in patients with type 2 diabetes]
    Hua Zhang
    Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated No 6 People s Hospital, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 87:2390-3. 2007
    ..To investigate the effect of single nucleotide polymorphism (SNP) + 45 of the adiponectin (ADIPOQ) gene on the response to therapy with rosiglitazone maleate in patients with type 2 diabetes...
  18. pmc A variation in NOS1AP gene is associated with repaglinide efficacy on insulin resistance in type 2 diabetes of Chinese
    Wen Qin
    Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai 200233, China
    Acta Pharmacol Sin 31:450-4. 2010
    ..To investigate a potential association between SNP rs10494366 in the neural nitric oxide synthase adaptor protein (NOS1AP) and efficacy of repaglinide (an insulin secretagogue) in newly diagnosed Shanghai Chinese type 2 diabetes patients...
  19. ncbi request reprint [Comparison of the application of three diagnostic criteria of metabolic syndrome in familial type 2 diabetic pedigrees]
    Xiao Jing Ma
    Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism of Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai 200233, China
    Zhonghua Yu Fang Yi Xue Za Zhi 43:489-94. 2009
    ....
  20. pmc PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population
    Cheng Hu
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, China
    PLoS ONE 4:e7643. 2009
    ..In this study, we attempt to analyze the independent and joint effect of variants from these loci on type 2 diabetes and clinical phenotypes related to glucose metabolism...
  21. ncbi request reprint Association of apelin genetic variants with type 2 diabetes and related clinical features in Chinese Hans
    Rong Zhang
    Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai 200233, China
    Chin Med J (Engl) 122:1273-6. 2009
    ..The plasma levels of apelin increased in obese patients and diabetic subjects. This study aimed to investigate the effects of apelin genetic variants on type 2 diabetes and related quantitative traits...
  22. ncbi request reprint [An analysis method to apply linkage disequilibrium maps to association study]
    Cheng Hu
    Shanghai Clinical Medicine Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated No 6 People s Hospital, Shanghai, 200233 PR China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 24:495-8. 2007
    ..To apply linkage disequilibrium (LD) maps to associations studies with high throughput single nucleotide polymorphisms (SNPs)...
  23. ncbi request reprint [Study on prevalence and risk factors of fatty liver of patients with type 2 diabetes]
    Jian Zhou
    Shanghai Clinical Center for Diabetes, Department of Endocrinology and Metabolism, Sixth People s Hospital, Jiaotong University, Shanghai Diabetes Institute, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 87:2249-52. 2007
    ..To study the prevalence and risk factors of nonalcoholic fatty liver (NAFL) of patients with type 2 diabetes...
  24. ncbi request reprint [Scanning the HNF4A gene mutation from Chinese pedigrees with early- and/or multiple-onset diabetes]
    Rong Zhang
    Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated No 6 People s Hospital, Shanghai Diabetes Clinical Center, Shanghai 200233, P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 23:406-9. 2006
    ..To screen the mutation of hepatocyte nuclear factor 4 alpha gene (HNF4A) in Chinese pedigrees with early and/or multiplex-onset diabetes in Shanghai and nearby area...
  25. doi request reprint Association of KCNJ11 and ABCC8 genetic polymorphisms with response to repaglinide in Chinese diabetic patients
    Ya yi He
    Department of Endocrinology and Metabolism, The Sixth People s Hospital, Shanghai Jiaotong University, Shanghai 200233, China
    Acta Pharmacol Sin 29:983-9. 2008
    ..The aim of this study was to investigate the association of KCNJ11 E23K and ABCC8 exon16-3T/C with the therapeutic effect of repaglinide in patients with type 2 diabetes...
  26. doi request reprint A common polymorphism of CYP4A11 is associated with blood pressure in a Chinese population
    Rong Zhang
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center of Diabetes, Shanghai, China
    Hypertens Res 34:645-8. 2011
    ..17, P = 0.0011) and diastolic blood pressure (β = -1.75, P = 0.0010) in men. A common variant on CYP4A11 was associated with blood pressure in a Chinese population. Future studies are needed to confirm our findings...
  27. pmc Glycated haemoglobin A1c for diagnosing diabetes in Chinese population: cross sectional epidemiological survey
    Yuqian Bao
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center of Diabetes, Shanghai 200233, China
    BMJ 340:c2249. 2010
    ..To evaluate haemoglobin A1c (HbA(1c)) in diagnosing diabetes and identify the optimal HbA(1c) threshold to be used in Chinese adults...
  28. ncbi request reprint [Study on prevalence of latent autoimmune diabetes in adults and its relationship with metabolic syndrome]
    Jian Zhou
    Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology Metabolism of Shanghai Jiaotong University Affiliated Sixth People s Hospital, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 89:1250-4. 2009
    ..To investigate the prevalence, clinical features of latent autoimmune diabetes in adults (LADA) from phenotypic type 2 diabetic patients and the relationship between LADA and metabolic syndrome (MS)...
  29. ncbi request reprint [Genetic characteristics of familial type 2 diabetes pedigrees: a preliminary analysis of 4468 persons from 715 pedigrees]
    Xiao Jing Ma
    Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism of Shanghai Jiaotong University Affiliated Sixth People s Hospital, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 88:2541-3. 2008
    ..To analyze the inheritance character of type 2 diabetes mellitus (T2DM) pedigrees...
  30. doi request reprint Phenotypic heterogeneity in Chinese patients with hepatocyte nuclear factor-1β mutations
    Congrong Wang
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Key Laboratory of Diabetes Mellitus, China
    Diabetes Res Clin Pract 95:119-24. 2012
    ..The aim of this study was to investigate clinical spectrum of hepatocyte nuclear factor-1β (HNF-1β) mutation in Chinese diabetic patients with renal dysfunction and/or structure abnormalities...
  31. pmc Genetic variations in APPL2 are associated with overweight and obesity in a Chinese population with normal glucose tolerance
    Shan Jiang
    Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, China
    BMC Med Genet 13:22. 2012
    ..In the current study, we aimed to test the impacts of APPL2 genetic variants on obesity in a Chinese population with normal glucose tolerance...
  32. pmc CPVL/CHN2 genetic variant is associated with diabetic retinopathy in Chinese type 2 diabetic patients
    Cheng Hu
    Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, China
    Diabetes 60:3085-9. 2011
    ..The aim of this study was to test the effects of single nucleotide polymorphisms (SNPs) from these four loci on diabetic nephropathy and retinopathy in Chinese type 2 diabetic patients...
  33. ncbi request reprint Association of a common haplotype of hepatocyte nuclear factor 1alpha with type 2 diabetes in Chinese population
    Cong Rong Wang
    Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai JiaoTong University Affiliated Sixth People s Hospital, Shanghai, China
    Biomed Environ Sci 20:41-6. 2007
    ..To analyze the association of variants of hepatocyte nuclear factor-1alpha (HNF-1alpha) gene with type 2 diabetes in Chinese population...
  34. ncbi request reprint Glycemic variability and its responses to intensive insulin treatment in newly diagnosed type 2 diabetes
    Jian Zhou
    Shanghai Clinical Center for Diabetes, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University, Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai, China
    Med Sci Monit 14:CR552-8. 2008
    ..This study investigated the characteristics of BG variability in type 2 diabetic patients and the effect of intensive treatment...
  35. ncbi request reprint [Relationship between blood glucose variability and microalbuminuria in type 2 diabetic patients with well-controlled glycosylated hemoglobin]
    Jian Zhou
    Shanghai Clinical Center for Diabetes, Department of Endocrinology and Metabolism, Shanghai Sixth People s Hospital Affiliated to Jiaotong University, Shanghai Diabetes Institute, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 88:2977-81. 2008
    ..To investigate the relationship between the blood glucose variability and microalbuminuria (MAU) in type 2 diabetic patients with well-controlled glycosylated hemoglobin (HbA1c) and the influencing factors of blood glucose variability...
  36. pmc Glycemic variability is associated with subclinical atherosclerosis in Chinese type 2 diabetic patients
    Yifei Mo
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, 600 Yishan Road, Shanghai, 200233, China
    Cardiovasc Diabetol 12:15. 2013
    ..We therefore investigated the association between glycemic variability and cervical and/or intracranial atherosclerosis in Chinese type 2 diabetic patients...
  37. pmc A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans
    Huaixing Li
    Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Graduate School of the Chinese Academy of Sciences, Shanghai, China
    Diabetes 62:291-8. 2013
    ..0169) but not with fasting glucose. Our findings not only provide new insights into the pathophysiology of T2D, but may also shed light on the ethnic differences in T2D susceptibility...
  38. doi request reprint Precise microdeletion detection of Prader-Willi Syndrome with array comparative genome hybridization
    Xin yu Shao
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai, China
    Biomed Environ Sci 23:194-8. 2010
    ..Our study was designed to precisely detect the microdeletions, which accounts for 65%-70% of the PWS...
  39. ncbi request reprint [The reference values of glycemic parameters for continuous glucose monitoring and its clinical application]
    Jian Zhou
    Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, The Sixth People s Hospital, Affiliated to Jiaotong University, Shanghai 200233, China
    Zhonghua Nei Ke Za Zhi 46:189-92. 2007
    ..To establish reference values of glycemic parameters for continuous glucose monitoring in Chinese...
  40. doi request reprint Genetic advances of type 2 diabetes in Chinese populations
    Weihui Yu
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University, Shanghai, China
    J Diabetes 4:213-20. 2012
    ..Despite many advances in the field of risk prediction and pharmacogenetics, the pace of clinical application of these findings is rather slow. As a result, more studies into the practical utility of these findings remain necessary...
  41. pmc Serum Proteome Changes in Healthy Subjects with Different Genotypes of NOS1AP in the Chinese Population
    Feng Jiang
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, 600 Yishan Road, Shanghai 200233, China
    J Diabetes Res 2013:357630. 2013
    ..05). The protein profiling changes between the genotypes of rs12742393 indicated that this SNP might play a role in the development of type 2 diabetes...
  42. pmc Ten-year changes in the prevalence of overweight, obesity and central obesity among the Chinese adults in urban Shanghai, 1998-2007 - comparison of two cross-sectional surveys
    Xuhong Hou
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Key Clinical Center for Metabolic Disease, 600 Yishan Road, Shanghai 200233, China
    BMC Public Health 13:1064. 2013
    ..However, there have been no comprehensive reports on secular trends in obesity prevalence among Chinese adults in urban Shanghai, which is the largest city in southern China...
  43. ncbi request reprint Pyrosequencing Is an Accurate and Reliable Method for the Analysis of Heteroplasmy of the A3243G Mutation in Patients with Mitochondrial Diabetes
    Jing Bin Yan
    Institute of Medical Genetics, Shanghai Children s Hospital, Shanghai Jiaotong University, Shanghai, Shanghai, China Department of Endocrinology and Metabolism, Shanghai JiaoTong University Affiliated Sixth People s Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center of Diabetes, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China
    J Mol Diagn 16:431-9. 2014
    ..This result suggested that the heteroplasmy of the A3243G mutation could become a significant prediction index for the onset of mitochondrial diabetes. ..
  44. pmc Cancer incidence and mortality in patients with type 2 diabetes treated with human insulin: a cohort study in Shanghai
    Yunjuan Gu
    Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai, China
    PLoS ONE 8:e53411. 2013
    ..The aim was to investigate the association between human insulin and cancer incidence and mortality in Chinese patients with type 2 diabetes...
  45. ncbi request reprint [Association between melanocortin 4 receptor gene polymorphisms and obesity]
    Rong Zhang
    Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated No 6 People s Hospital, Shanghai 200233, China
    Zhonghua Yi Xue Za Zhi 87:96-9. 2007
    ..To investigate the association between the polymorphisms of melanocortin-4 receptor (MC4R) gene and obesity...
  46. pmc A novel mutation in leptin gene is associated with severe obesity in chinese individuals
    Yue Zhao
    Translational Medical Center, Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, 600 Yishan Road, Shanghai 200233, China
    Biomed Res Int 2014:912052. 2014
    ..0 kg/m(2). This mutation was not identified in the controls. We speculated that the mutation H118L in LEP might be associated with severe obesity in Chinese subjects. However, the substantial mechanism should be further investigated. ..
  47. pmc Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application
    Xue Sun
    Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People s Hospital, Shanghai 200233, China
    Biomed Res Int 2014:926713. 2014
    ..This review covers the major genetic studies on the risk of T2D based on ethnicity and briefly discusses the potential mechanisms and clinical utility of the genetic information underlying T2D. ..