Research Topics
| Z Y ChenSummaryAffiliation: Shanghai Second Medical University Country: China Publications
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Detail Information
Publications
Human glial cell-line-derived neurotrophic factor: a structure-function analysisZ Y Chen
Department of Neurobiology, Second Military Medical University, 800 Xiangyin Road, Shanghai, 200433, China
Biochem Biophys Res Commun 268:692-6. 2000....
Glial cell line-derived neurotrophic factor promotes survival and induces differentiation through the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathway respectively in PC12 cellsZ Chen
Department of Neurobiology, The Second Military Medical University, 800 Xiangyin Road, 200433, Shanghai, China
Neuroscience 104:593-8. 2001..Therefore, it is inferred that similar intracellular signaling components are used by distinct growth factors toward a common biological effect...
Glial cell line-derived neurotrophic factor enhances axonal regeneration following sciatic nerve transection in adult ratsZ Y Chen
Department of Neurobiology, The Second Military Medical University, 800 Xiangyin Road, 200433, Shanghai, China
Brain Res 902:272-6. 2001..COL group. These data provide strong evidence that GDNF could promote axonal regeneration in adult rats, suggesting the potential use of GDNF in therapeutic approaches to peripheral nerve injury and neuropathies...
Development of neurotrophic molecules for treatment of neurodegenerationZ Y Chen
Department of Neurobiology, The Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, China
Curr Protein Pept Sci 2:261-76. 2001..This review focuses on some of the major themes and lines of mechanistic and therapeutic advances in this fast-moving field of neuroscience...
[Protective effect of exogenous glial cell line derived neurotrophic factor on neurons after sciatic nerve injury in rats]Z Y Chen
Department of Neurobiology, Second Military Medical University, Shanghai 200433, China
Sheng Li Xue Bao 52:295-300. 2000..These results suggest that exogenous GDNF is capable of protecting motor neurons from death induced by peripheral nerve injury...
