Qing Xin Liu


Affiliation: Shandong Agricultural University
Country: China


  1. Liu Q, Wang X, Ikeo K, Hirose S, Gehring W, Gojobori T. Evolutionarily conserved transcription factor Apontic controls the G1/S progression by inducing cyclin E during eye development. Proc Natl Acad Sci U S A. 2014;111:9497-502 pubmed publisher
    ..These observations identify a pathway crucial for eye development, governed by a mechanism in which Cyclin E promotes the G1-to-S phase transition when regulated by Apt. ..
  2. Sun X, Ding Y, Zhan M, Li Y, Gao D, Wang G, et al. Usp7 regulates Hippo pathway through deubiquitinating the transcriptional coactivator Yorkie. Nat Commun. 2019;10:411 pubmed publisher
    ..In summary, our findings demonstrate that Yki/Yap is stabilized by Usp7/HAUSP, and provide HAUSP as a potential therapeutic target for HCC. ..
  3. Shen Y, Wang L, Hirose S, Zhou Z, Liu Q. The transcriptional factor Apt regulates neuroblast differentiation through activating CycE expression. Biochem Biophys Res Commun. 2018;499:889-894 pubmed publisher
    ..On the other hand, Gcm suppresses Apt expression in the NB6-4A cell, thus inhibiting CycE expression. Taken together, our findings reveal a Gcm-Apt-CycE axis that regulates neuroblast and glia cell differentiation. ..
  4. Li X, Yu Q, Zhou Q, Zhao X, Liu Z, Cui W, et al. BmRobo1a and BmRobo1b control axon repulsion in the silkworm Bombyx mori. Gene. 2016;577:215-20 pubmed publisher
    ..Our results suggest that BmRobo1a and BmRobo1b have repulsive function in axon guidance, even though their structures are different from Robo1 of other species. ..
  5. Zhao X, Liu Z, Liu Q. Gene coexpression networks reveal key drivers of phenotypic divergence in porcine muscle. BMC Genomics. 2015;16:50 pubmed publisher
    ..Our results present multiple lines of evidence suggesting links between modules and muscle phenotypes, and provide insights into the molecular bases of genome organization in muscle development and phenotype variation. ..
  6. Li X, Yu Q, Zhou Q, Zhao X, Liu Z, Cui W, et al. BmRobo2/3 is required for axon guidance in the silkworm Bombyx mori. Gene. 2016;577:174-9 pubmed publisher
    ..These data demonstrate that BmRobo2/3 is required for axon guidance in the silkworm. ..
  7. Liu Z, Yu Q, Yang C, Meng M, Ren C, Mu Z, et al. Transcription factor SGF1 is critical for the neurodevelopment in the silkworm, Bombyx mori. Gene. 2016;587:70-5 pubmed publisher
    ..Knockdown of Bmsgf1 by RNA interference (RNAi) results in abnormal development of axons. Therefore, our results demonstrate that BmSGF1 is an indispensable regulator for neurodevelopment. ..
  8. Wang X, Shen Y, Cheng Q, Fu C, Zhou Z, Hirose S, et al. Apontic directly activates hedgehog and cyclin E for proper organ growth and patterning. Sci Rep. 2017;7:12470 pubmed publisher
    ..The discovery of the simultaneous expression of Hh and principal cell-cycle regulator Cyclin E by Apt implicates insight into the mechanism by which deregulated hh and cyclin E promotes tumor formation...