Yue Zhong Li


Affiliation: Shandong University
Country: China


  1. Zhuo L, Zhang Z, Pan Z, Sheng D, Hu W, Li Y. CIRCE element evolved for the coordinated transcriptional regulation of bacterial duplicate groELs. Biochim Biophys Acta Gene Regul Mech. 2018;1861:928-937 pubmed publisher
    ..Based on promoter-sequence characteristics, we proposed a model of the coordinated regulation of the transcription of duplicate groELs in M. xanthus DK1622. ..
  2. Zhang Z, Wang J, Gong Y, Li Y. Contributions of substitutions and indels to the structural variations in ancient protein superfamilies. BMC Genomics. 2018;19:771 pubmed publisher
    ..The regular clock exists not only in protein sequences, but also probably in protein structures. ..
  3. Yang Y, Singh R, Lan X, Zhang C, Li Y, Li Y, et al. Genome Editing in Model Strain Myxococcus xanthus DK1622 by a Site-Specific Cre/loxP Recombination System. Biomolecules. 2018;8: pubmed publisher
    ..xanthus. This Cre/loxP-mediated recombination could serve as an alternative genetic manipulation method. ..
  4. request reprint
    Li Y, Hu W, Zhang Y, Qiu Z, Zhang Y, Wu B. A simple method to isolate salt-tolerant myxobacteria from marine samples. J Microbiol Methods. 2002;50:205-9 pubmed
    ..e. lower than 60% seawater (about 2.0% salt content) or distilled water supplemented with MgCl(2). The method picked up the fruiting bodies for isolation. ..
  5. Zhu L, Yue X, Han K, Li Z, Zheng L, Yi X, et al. Allopatric integrations selectively change host transcriptomes, leading to varied expression efficiencies of exotic genes in Myxococcus xanthus. Microb Cell Fact. 2015;14:105 pubmed publisher
    ..Allopatric integrations selectively change host transcriptomes, which lead to varied expression efficiencies of exotic genes. ..
  6. Yue X, Cui X, Zhang Z, HU W, Li Z, Zhang Y, et al. Effects of transcriptional mode on promoter substitution and tandem engineering for the production of epothilones in Myxococcus xanthus. Appl Microbiol Biotechnol. 2018;102:5599-5610 pubmed publisher
    ..Our study provides an insight into exploiting powerful promoters to produce valuable secondary metabolites, especially in host with limited known promoters. ..
  7. Wang Y, Li Y. Cultivation to improve in vivo solubility of overexpressed arginine deiminases in Escherichia coli and the enzyme characteristics. BMC Biotechnol. 2014;14:53 pubmed publisher
    ..The present study suggested a new strategy to increase the solubilization of overexpressed recombinant proteins in E. coli cells. ..
  8. Peng R, Wang Y, Feng W, Yue X, Chen J, Hu X, et al. CRISPR/dCas9-mediated transcriptional improvement of the biosynthetic gene cluster for the epothilone production in Myxococcus xanthus. Microb Cell Fact. 2018;17:15 pubmed publisher
    ..This is the first time to construct the CRISPR/dCas9 activation system in myxobacteria and the first time to assay the CRISPR/dCas9 activations for the biosynthesis of microbial secondary metabolites. ..
  9. Zhao J, Zhong L, Shen M, Xia Z, Cheng Q, Sun X, et al. Discovery of the autonomously replicating plasmid pMF1 from Myxococcus fulvus and development of a gene cloning system in Myxococcus xanthus. Appl Environ Microbiol. 2008;74:1980-7 pubmed publisher
    ..The transformants subsequently exhibited the ability to form pili and social motility. Autonomously replicating plasmid pMF1 provides a new tool for genetic manipulation in Myxococcus...

More Information


  1. Yue X, Cui X, Zhang Z, Peng R, Zhang P, Li Z, et al. A bacterial negative transcription regulator binding on an inverted repeat in the promoter for epothilone biosynthesis. Microb Cell Fact. 2017;16:92 pubmed publisher
    ..Esi binds to the epothilone promoter and down-regulates the transcriptional level of the whole gene cluster to affect the biosynthesis of epothilone. This is the first transcription regulator identified for epothilone biosynthesis. ..
  2. Yang Y, Wang Y, Li Z, Gong Y, Zhang P, Hu W, et al. Increasing on-target cleavage efficiency for CRISPR/Cas9-induced large fragment deletion in Myxococcus xanthus. Microb Cell Fact. 2017;16:142 pubmed publisher
    ..xanthus DK1622 and its epothilone-producing mutant. The findings and the proposals described in this paper were suggested to be workable in other organisms, for example, other Gram negative bacteria with high GC content. ..