Research Topics
Genomes and Genes | Wei LiSummaryAffiliation: Shandong University Country: China Publications
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Publications
Inhibitor of DNA-binding-1/inhibitor of differentiation-1 (ID-1) is implicated in various aspects of gastric cancer cell biologyWei Li
Biomedical Engineering Institute, School of Control Science and Engineering, Shandong University, Jinan, 250021 Shandong, China
Mol Biol Rep 39:3009-15. 2012..Collectively, these findings demonstrate that ID-1 plays pivotal and diverse roles in the biology of certain gastric cancer cells, further suggesting that ID-1 is implicated in the pathogenesis and progression of gastric cancer...- Treatment of prostate cancer cells with adenoviral vector-mediated antisense RNA using androgen-dependent and androgen-independent promotersWei Li
Biomedical Engineering Institution, School of Control Science and Engineering, Shandong University, Jinan, Shandong 250061, China
Med Oncol 27:519-30. 2010.... - Targeted antitumor effect induced by hTERT promoter mediated ODC antisense adenovirusWei Wang
Institute of Biochemistry and Molecular Biology, School of Medicine, Shandong University, 250012, Jinan, China
Mol Biol Rep 37:3239-47. 2010..Our research offers a powerful and safe new therapeutic strategy for cancer targeted treatment... - RNA interference of human papillomavirus type 16 E7 increases HLA class I antigen expression in HaCaT-E7 cellsXiao mei Deng
Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China
Int J Gynecol Cancer 21:28-34. 2011..The purpose of this study was to determine whether knockdown of HPV16 E7 could up-regulate surface HLA class I antigen expression in HPV16 E7 expressing HaCaT cells (HaCaT-E7)... 
The potential role of ORM2 in the development of colorectal cancerXuHua Zhang
Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, Shandong, China
PLoS ONE 7:e31868. 2012..001). ITRAQ together with Q-TOF/MS is a sensitive and reproducible technique of quantitative proteomics. Alteration in expression of ORM2 suggests that ORM2 could be used as a potential biomarker in the diagnosis of CRC...- MiR-429 is an independent prognostic factor in colorectal cancer and exerts its anti-apoptotic function by targeting SOX2Juan Li
Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, Shandong Province, China
Cancer Lett 329:84-90. 2013..Taken together, our data suggest for the first time that miR-429 could play an oncogenic role in the cellular processes of CRC and represent a novel prognostic biomarker for CRC... - Sox2 nuclear expression is closely associated with poor prognosis in patients with histologically node-negative oral tongue squamous cell carcinomaLutao Du
Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, PR China
Oral Oncol 47:709-13. 2011..According to our results, Sox2 positive expression was frequent in pN0 OTSCC and involved in tumor progression. The measurement of Sox2 expression may be helpful in predicting relapse and prognosis of patients with pN0 OTSCC... 
Adenovirus-mediated expression of spermidine/spermine N1-acetyltransferase gene induces S-phase arrest in human colorectal cancer cellsHui Sun
Institute of Biochemistry and Molecular Biology, School of Medicine, Shandong University, Jinan, P R China
Oncol Rep 20:1229-35. 2008....- Overexpression of Bmi-1 in uterine cervical cancer: correlation with clinicopathology and prognosisXin Zhang
Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China
Int J Gynecol Cancer 20:1597-603. 2010..The aim of this study was to investigate the expression of Bmi-1 protein in human uterine cervical cancer (UCC) and explore its associations with clinicopathological factors and prognosis... - Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritisLei Zhang
Department of Orthopedics, Qilu Hospital, Shandong University, Jinan, China
PLoS ONE 7:e31000. 2012..So we examined the frequencies of Th22 cells, Th17 cells and Th1 cells in peripheral blood (PB) from patients with AS and patients with RA compared with both healthy controls as well as patients with osteoarthritis... - Adenovirus vector-mediated upregulation of spermidine /spermine N1-acetyltransferase impairs human gastric cancer growth in vitro and in vivoBin Liu
Institute of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, Shandong, 250012, PR China
Cancer Sci 100:2126-32. 2009..Ad-SSAT arrested gastric cancer cells in S phase, which was mediated through downregulation of the cyclin A-E2F signaling pathway... - Human leukocyte antigen-G is closely associated with tumor immune escape in gastric cancer by increasing local regulatory T cellsLutao Du
Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan, China
Cancer Sci 102:1272-80. 2011..Thus, HLA-G might be a promising predictor for disease prognosis and a possible novel target for immunotherapy in GC patients... - Clinical and molecular genetic analysis in Chinese patients with distal myopathy with rimmed vacuolesHonghao Li
Department of Neurology and Laboratory of Neuromuscular Disorders, Qilu Hospital of Shandong University, Jinan, China
J Hum Genet 56:335-8. 2011..1523T>C (p.L508S) was 25% in the Chinese patients with DMRV. Our findings expand the genetic spectrum of DMRV and indicate that the common mutations of GNE gene in DMRV may be variable among different ethnic populations... - Serum sHLA-G levels: a useful indicator in distinguishing colorectal cancer from benign colorectal diseasesCheng Bao Zhu
Department of Clinical Laboratory, Jinan Infectious Disease Hospital, Jinan, Shandong, People s Republic of China
Int J Cancer 128:617-22. 2011.... - [Study on the genotyping of human papillomavirus using a new DNA liquid chip in women of high-risk group of Shandong province]Min Liu
Department of Clinical Laboratory, Qilu Hospital, Shandong University, Jinan 250012, China
Zhonghua Liu Xing Bing Xue Za Zhi 28:487-90. 2007..To evaluate the diagnostic applicability of human papillomavirus (HPV) liquid chip assay which is based on Luminex XMAP System, and perform a HPV epidemiologic study with the liquid chip in women of Shandong province... - Effect of areca on contraction of colonic muscle strips in ratsDong Ping Xie
Department of Physiology, Medical College, Shandong University, Jinan 250012, Shandong Province, China
World J Gastroenterol 8:350-2. 2002..To investigate the effects of areca on the contractile activity of isolated colonic muscle strips in rats and mechanism involved... - Novel PNPLA2 gene mutations in Chinese Han patients causing neutral lipid storage disease with myopathyPengfei Lin
Department of Neurology, Qilu Hospital of Shandong University, Key Laboratory for Experimental Teratology of the Ministry of Education, Shandong University, Shandong, China
J Hum Genet 57:679-81. 2012..The identification and study of mutations found in PNPLA2 is also particularly important to define the clinical spectrum and genotype-phenotype correlations of the PNPLA2 gene... - Effects of antisense RNA targeting of ODC and AdoMetDC on the synthesis of polyamine synthesis and cell growth in prostate cancer cells using a prostatic androgen-dependent promoter in adenovirusWei Li
Institute of Biochemistry and Molecular Biology, School of Medicine, Shandong University, Jinan, Shandong, China
Prostate 68:1354-61. 2008..We also examined the potential of this construct for prostate cancer therapy... - Down-regulation of HLA class I antigen in human papillomavirus type 16 E7 expressing HaCaT cells: correlate with TAP-1 expressionWei Li
Department of Clinical Laboratory, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, China
Int J Gynecol Cancer 20:227-32. 2010.... - Elevated Th22 cells correlated with Th17 cells in patients with rheumatoid arthritisLei Zhang
Department of Orthopedics, Qilu Hospital, Shandong University, Jinan, 250012, China
J Clin Immunol 31:606-14. 2011..T-helper (Th) 22 and Th17 cells are implicated in the pathogenesis of autoimmune diseases. The roles of Th22 cells in the pathophysiology of rheumatoid arthritis (RA) remain unsettled... - Riboflavin-responsive lipid-storage myopathy caused by ETFDH gene mutationsBing Wen
Laboratory of Neuromuscular Disorders and Department of Neurology, Qilu Hospital, Shandong University, Jinan, PR China
J Neurol Neurosurg Psychiatry 81:231-6. 2010..In the past 15 years, more than 200 cases of LSM have been reported in the Chinese literature, but the accurate pathogenic mechanisms are still unknown... - A new homoisoflavan from Caesalpinia sappanHuanxin Zhao
Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan, 250062, China
J Nat Med 62:325-7. 2008..together with seven known phenolic compounds. The structure of the new compound (1) was determined on the basis of spectroscopic analysis...