Xiao yan Zhu
Affiliation: Second Military Medical University
Zhang Y, Liu Y, Mao Y, Dong W, Zhu X, Jiang L. Resveratrol ameliorates lipopolysaccharide-induced epithelial mesenchymal transition and pulmonary fibrosis through suppression of oxidative stress and transforming growth factor-Î²1 signaling. Clin Nutr. 2015;34:752-60 pubmed publisher
..Application of antioxidants may represent a useful adjuvant pharmacologic approach to reduce ARDS-associated pulmonary fibrosis. ..
Wang C, Duan G, Liu Y, Yu Q, Tang X, Zhao W, et al
. Overproduction of nitric oxide by endothelial cells and macrophages contributes to mitochondrial oxidative stress in adrenocortical cells and adrenal insufficiency during endotoxemia. Free Radic Biol Med. 2015;83:31-40 pubmed publisher
Dong W, Liu Y, Lv Z, Mao Y, Wang Y, Zhu X, et al
. Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism. Free Radic Biol Med. 2015;88:404-416 pubmed publisher
..These protective effects of resveratrol might be mediated through an Nrf2-dependent mechanism. ..
Du J, Cong B, Yu Q, Wang H, Wang L, Wang C, et al
. Upregulation of microRNA-22 contributes to myocardial ischemia-reperfusion injury by interfering with the mitochondrial function. Free Radic Biol Med. 2016;96:406-17 pubmed publisher
Tang X, Wang C, Zhu X, Ni X. Rosiglitazone inhibition of calvaria-derived osteoblast differentiation is through both of PPARÎ³ and GPR40 and GSK3Î²-dependent pathway. Mol Cell Endocrinol. 2015;413:78-89 pubmed publisher
..These results suggest that both PPARÎ³ and GRP40 are required for RSG-induced inhibition of mouse calvaria osteoblast differentiation, which is mediated through GSK3Î²-dependent pathway. ..
Tang X, Wang C, Zhu X, Ni X. Protein tyrosine phosphatase SHP-1 modulates osteoblast differentiation through direct association with and dephosphorylation of GSK3?. Mol Cell Endocrinol. 2017;439:203-212 pubmed publisher
..Downregulation of SHP-1 may contribute to RSG-induced inhibition of mouse calvaria osteoblast differentiation by activating GSK3?-dependent pathway. ..
Chen W, Du J, Hu X, Yu Q, Li D, Wang C, et al
. Protective effects of resveratrol on mitochondrial function in the hippocampus improves inflammation-induced depressive-like behavior. Physiol Behav. 2017;182:54-61 pubmed publisher
..These findings support the potential for resveratrol as a possible pharmacological agent for depression treatment in the future. ..