Chao Yu Miao

Summary

Affiliation: Second Military Medical University
Country: China

Publications

  1. doi request reprint Nicotinamide phosphoribosyltransferase is required for the calorie restriction-mediated improvements in oxidative stress, mitochondrial biogenesis, and metabolic adaptation
    Jie Song
    Department of Pharmacology, Second Military Medical University, Room 506, 325 Guo He Road, Yangpu District, Shanghai 200433, China or
    J Gerontol A Biol Sci Med Sci 69:44-57. 2014
  2. pmc The role of perivascular adipose tissue in vascular smooth muscle cell growth
    Chao Yu Miao
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Br J Pharmacol 165:643-58. 2012
  3. doi request reprint Circulating and local visfatin/Nampt/PBEF levels in spontaneously hypertensive rats, stroke-prone spontaneously hypertensive rats and Wistar-Kyoto rats
    Pei Wang
    Department of Pharmacology, Second Military Medical University, 325 Guo He Road, Shanghai, 200433, China
    J Physiol Sci 60:317-24. 2010
  4. ncbi request reprint Effects of long-term treatment with candesartan on hemodynamics and organ damage in spontaneously hypertensive rats
    He Hui Xie
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Cardiovasc Drugs Ther 19:391-7. 2005
  5. ncbi request reprint Synergism of atenolol and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats
    He Hui Xie
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    J Hypertens 23:193-201. 2005
  6. ncbi request reprint Importance of blood pressure variability in organ protection in spontaneously hypertensive rats treated with combination of nitrendipine and atenolol
    He Hui Xie
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 23:1199-204. 2002
  7. ncbi request reprint Synergism of atenolol and amlodipine on lowering and stabilizing blood pressure in spontaneously hypertensive rats
    Li Ping Xu
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Fundam Clin Pharmacol 18:33-8. 2004
  8. ncbi request reprint Blood pressure variability and baroreflex sensitivity are not different in spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats
    Lin Shu Zhan
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 26:959-62. 2005
  9. pmc Loss of AMP-activated protein kinase-α2 impairs the insulin-sensitizing effect of calorie restriction in skeletal muscle
    Pei Wang
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Diabetes 61:1051-61. 2012
  10. ncbi request reprint Contribution of blood pressure variability to the effect of nitrendipine on end-organ damage in spontaneously hypertensive rats
    Jian Guo Liu
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    J Hypertens 21:1961-7. 2003

Collaborators

Detail Information

Publications52

  1. doi request reprint Nicotinamide phosphoribosyltransferase is required for the calorie restriction-mediated improvements in oxidative stress, mitochondrial biogenesis, and metabolic adaptation
    Jie Song
    Department of Pharmacology, Second Military Medical University, Room 506, 325 Guo He Road, Yangpu District, Shanghai 200433, China or
    J Gerontol A Biol Sci Med Sci 69:44-57. 2014
    ..Collectively, our data provide the first evidence that the CR-induced beneficial effects in oxidative stress, mitochondrial biogenesis, and metabolic adaptation require NAMPT. ..
  2. pmc The role of perivascular adipose tissue in vascular smooth muscle cell growth
    Chao Yu Miao
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Br J Pharmacol 165:643-58. 2012
    ....
  3. doi request reprint Circulating and local visfatin/Nampt/PBEF levels in spontaneously hypertensive rats, stroke-prone spontaneously hypertensive rats and Wistar-Kyoto rats
    Pei Wang
    Department of Pharmacology, Second Military Medical University, 325 Guo He Road, Shanghai, 200433, China
    J Physiol Sci 60:317-24. 2010
    ..Thus, our results may provide useful information for understanding the characteristic of visfatin in hypertensive models, and support the view that visfatin may be a myokine...
  4. ncbi request reprint Effects of long-term treatment with candesartan on hemodynamics and organ damage in spontaneously hypertensive rats
    He Hui Xie
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Cardiovasc Drugs Ther 19:391-7. 2005
    ....
  5. ncbi request reprint Synergism of atenolol and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats
    He Hui Xie
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    J Hypertens 23:193-201. 2005
    ....
  6. ncbi request reprint Importance of blood pressure variability in organ protection in spontaneously hypertensive rats treated with combination of nitrendipine and atenolol
    He Hui Xie
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 23:1199-204. 2002
    ..To study the importance of reduction of blood pressure variability (BPV) in the organ protection of long-term treatment with combination of nitrendipine and atenolol, which was abbreviated as Nile, in spontaneously hypertensive rats (SHR)...
  7. ncbi request reprint Synergism of atenolol and amlodipine on lowering and stabilizing blood pressure in spontaneously hypertensive rats
    Li Ping Xu
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Fundam Clin Pharmacol 18:33-8. 2004
    ..The synergistic effect is highest when the dose proportion of the two drugs is 10 : 1...
  8. ncbi request reprint Blood pressure variability and baroreflex sensitivity are not different in spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats
    Lin Shu Zhan
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 26:959-62. 2005
    ..To demonstrate and compare hemodynamic phenotypes of blood pressure (BP), blood pressure variability (BPV) and baroreflex sensitivity (BRS) in genetic hypertensive rats...
  9. pmc Loss of AMP-activated protein kinase-α2 impairs the insulin-sensitizing effect of calorie restriction in skeletal muscle
    Pei Wang
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Diabetes 61:1051-61. 2012
    ..Our results suggest that AMPK may be modulated by CR in a ubiquitylation-dependent manner and acts as a chief dictator for the insulin-sensitizing effects of CR in skeletal muscle...
  10. ncbi request reprint Contribution of blood pressure variability to the effect of nitrendipine on end-organ damage in spontaneously hypertensive rats
    Jian Guo Liu
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    J Hypertens 21:1961-7. 2003
    ....
  11. ncbi request reprint The importance of blood pressure variability in rat aortic and left ventricular hypertrophy produced by sinoaortic denervation
    Chao Yu Miao
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai, China
    J Hypertens 20:1865-72. 2002
    ..The main objective was to examine the role of hemodynamics in rat aortic and left ventricular hypertrophy produced by sinoaortic denervation (SAD)...
  12. ncbi request reprint Restoration of arterial baroreflex function contributes to organ protection in spontaneously hypertensive rats treated with long-term hydrochlorothiazide mixture
    Ze An Lu
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai, China
    Clin Exp Pharmacol Physiol 30:49-54. 2003
    ..5. In conclusion, long-term treatment of rats with HCTM prevented hypertensive organ damage. Restoration of arterial baroreflex function contributes to organ protection in SHR treated in the long term with HCTM...
  13. doi request reprint Visfatin is associated with lipid metabolic abnormalities in Lyon hypertensive rats
    Pei Wang
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Clin Exp Pharmacol Physiol 37:894-9. 2010
    ..4. In conclusion, the results of the present study demonstrate that serum visfatin levels in LH rats are elevated and are associated with lipid metabolic abnormalities...
  14. doi request reprint Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia
    Pei Wang
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Autophagy 8:77-87. 2012
    ..Our results demonstrate that Nampt promotes neuronal survival through inducing autophagy via regulating TSC2-mTOR-S6K1 signaling pathway in a SIRT1-dependent manner during cerebral ischemia...
  15. ncbi request reprint Effects of long-term treatment with candesartan on organ damages in sinoaortic denervated rats
    He Hui Xie
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai 200433, China
    J Cardiovasc Pharmacol 41:325-31. 2003
    ..Restoration of arterial baroreflex function, decrease in BPV, and blockade of activated renin-angiotensin system may contribute to the organ protective action of candesartan in SAD rats...
  16. ncbi request reprint Arterial baroreflex function in conscious rats
    Ding feng Su
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 23:673-9. 2002
    ..Ketanserin improved the impaired ABR function in SHR. Finally, the possibility to develop a strain of rats with spontaneous deficiency on ABR function is mentioned...
  17. ncbi request reprint Blood pressure, baroreflex sensitivity, and end organ damage in hybrid offspring of spontaneously hypertensive rats and Sprague-Dawley rats
    He Hui Xie
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 26:1049-56. 2005
    ..To investigate the blood pressure (BP), baroreflex sensitivity (BRS), and organ damage in hybrids of spontaneously hypertensive rats and Sprague-Dawley rats...
  18. ncbi request reprint Restoration of baroreflex function by ketanserin is not blood pressure dependent in conscious freely moving rats
    Yan Jun Fu
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    J Hypertens 22:1165-72. 2004
    ..The present work was designed to test the hypothesis that the restoration of BRS by ketanserin is not dependent on BP level in conscious rats...
  19. ncbi request reprint Effects of long-term treatment with ketanserin on blood pressure variability and end-organ damage in spontaneously hypertensive rats
    Wen min Du
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai, China
    J Cardiovasc Pharmacol 41:233-9. 2003
    ..In conclusion, long-term treatment with ketanserin reduced hypertensive organ damage. Lowering BP, decreasing BPV, and ameliorating arterial baroreflex function may contribute together to this effect...
  20. ncbi request reprint Comparative study of sinoaortic denervated rats and spontaneously hypertensive rats
    Chao Yu Miao
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai, China
    Am J Hypertens 16:585-91. 2003
    ..Both hypertension and high blood pressure variability (BPV) are involved in cardiovascular damage. This comparative study was designed to explore the possible effects of both of these phenomena on the cardiovascular system...
  21. ncbi request reprint Two useful methods for evaluating antihypertensive drugs in conscious freely moving rats
    Ding feng Su
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 25:148-51. 2004
    ..They were the directly intragastric administration of drugs and modified probability sum test for evaluating the synergism of the combination of two drugs...
  22. ncbi request reprint Arterial baroreflex dysfunction promotes atherosclerosis in rats
    Guo jun Cai
    Department of Pharmacology, Second Military Medical University, 325 Guo He Road, Shanghai 200433, China
    Atherosclerosis 183:41-7. 2005
    ..These results indicate that arterial baroreflex dysfunction promotes the development of atherosclerosis in rats, and that inflammation may be involved in this process...
  23. ncbi request reprint Asynchronism of the recovery of baroreflex sensitivity, blood pressure, and consciousness from anesthesia in rats
    Wuliya Yi-Ming
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    J Cardiovasc Pharmacol 43:1-7. 2004
    ..In conclusion, after anesthesia, BRS inhibition is more obvious than BP reduction, and the recovery of BRS lags behind the recovery of consciousness or BP...
  24. ncbi request reprint Blood pressure variability is more important than blood pressure level in determination of end-organ damage in rats
    Chao Yu Miao
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    J Hypertens 24:1125-35. 2006
    ..This study was designed to determine how important a novel risk factor of elevated blood pressure variability (BPV) is in the determination of end-organ damage by comparison with the classic risk factor of a high blood pressure (BP) level...
  25. ncbi request reprint Effects of glucose-insulin-potassium on baroreflex sensitivity, left ventricular function and ventricular arrhythmia in the subacute phase of myocardial infarction in rats
    Jian Guo Liu
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai 200433, China
    Fundam Clin Pharmacol 17:443-8. 2003
    ..It is proposed that reducing ventricular arrhythmia and improving left ventricular function contribute to the effect of GIK on reducing the mortality after MI...
  26. ncbi request reprint Candesartan inhibits sinoaortic denervation-induced cardiovascular hypertrophy in rats
    Chao Yu Miao
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 23:713-20. 2002
    ..To study the effect of candesartan cilexetil (candesartan), a new AT1 receptor antagonist, on sinoaortic denervation (SAD)-induced cardiovascular hypertrophy and its potential mechanisms in rats...
  27. ncbi request reprint Angiotensin II and AT1 receptor in hypertrophied ventricles and aortas of sinoaortic-denervated rats
    Chao Yu Miao
    Department of Pharmacology, Basic Medical College, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 24:812-8. 2003
    ..The present study was to observe these two factors in the hypertrophied ventricles and aortas of sinoaortic-denervated rats...
  28. ncbi request reprint Morphological evidence of reinnervation of the baroreceptive regions in sinoaortic-denervated rats
    Guo jun Cai
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Clin Exp Pharmacol Physiol 30:925-9. 2003
    ....
  29. pmc Chronic exposure to nicotine enhances insulin sensitivity through α7 nicotinic acetylcholine receptor-STAT3 pathway
    Tian Ying Xu
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    PLoS ONE 7:e51217. 2012
    ..Our results contribute not only to the understanding of the pharmacological effects of nicotine, but also to the identifying of new therapeutic targets against insulin resistance...
  30. doi request reprint 4-Phenyl butyric acid does not generally reduce glucose levels in rodent models of diabetes
    Tian Ying Xu
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Clin Exp Pharmacol Physiol 37:441-6. 2010
    ....
  31. doi request reprint Effects of ketanserin on endotoxic shock and baroreflex function in rodents
    Chong Liu
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    J Infect Dis 204:1605-12. 2011
    ..The present work tested the hypothesis that restoration of baroreflex function is an effective treatment for lipopolysaccharide (LPS)-induced shock...
  32. pmc Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass- and obesity-associated (FTO) downregulation during energy restriction
    Pei Wang
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Mol Med 17:523-32. 2011
    ..Thus, our results provide the first evidence that the LepRb-STAT3 signaling pathway is involved in the brain FTO downregulation during ER...
  33. doi request reprint Telemetric ambulatory arterial stiffness index, a predictor of cardio-cerebro-vascular mortality, is associated with aortic stiffness-determining factors
    Zhi Yong Li
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    CNS Neurosci Ther 19:667-74. 2013
    ..However, there has been no research on the direct relationships between AASI and arterial stiffness-determining factors...
  34. ncbi request reprint Frequent ventricular premature beats increase blood pressure variability in rats
    Chao Yu Miao
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 25:545-53. 2004
    ..The present study was designed to test a hypothesis that nonfatal ventricular arrhythmia such as ventricular premature beats (VPB) is a contributing factor in the elevation of blood pressure variability (BPV)...
  35. doi request reprint Adipokines in inflammation, insulin resistance and cardiovascular disease
    Zhi Yong Li
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Clin Exp Pharmacol Physiol 38:888-96. 2011
    ..In particular, we focus on the effects of various adipokines in pathological processes, which may provide an insight into obesity-linked CVD and facilitate the development of new therapeutic strategies...
  36. ncbi request reprint ATP-sensitive potassium channels are involved in adenosine-induced reduction of blood pressure variability in spontaneously hypertensive rats
    Fu Ming Shen
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    J Cardiovasc Pharmacol 44:87-92. 2004
    ..These results suggest that the effect of adenosine on blood pressure variability in spontaneously hypertensive rats is due to activation of ATP-sensitive potassium channels mediated by adenosine A2-receptor...
  37. doi request reprint Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway
    Pei Wang
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Ann Neurol 69:360-74. 2011
    ..However, the role of Nampt in brain and stroke remains to be investigated...
  38. ncbi request reprint Increased susceptibility of ventricular arrhythmias to aconitine in anaesthetized rats is attributed to the inhibition of baroreflex
    He Shu
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Clin Exp Pharmacol Physiol 31:249-53. 2004
    ..00 and 17.00 h in anaesthetized rats. 6. In conclusion, anaesthesia may increase the risk of ventricular arrhythmias following aconitine. Intact arterial baroreflex function is necessary to prevent drug-induced ventricular arrhythmias...
  39. doi request reprint Deficiency of NG2+ cells contributes to the susceptibility of stroke-prone spontaneously hypertensive rats
    Pei Wang
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    CNS Neurosci Ther 17:327-32. 2011
    ..The purpose of this study is to investigate whether the NG2(+) cells, a class of oligodendrocyte progenitor cells, is involved in the pathophysiology of stroke in stroke-prone spontaneously hypertensive rat (SHR-SP)...
  40. doi request reprint Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide
    Pei Wang
    Department of Pharmacology, Second Military Medical University, 325 Guo He Road, Shanghai 200433, People s Republic of China
    Cardiovasc Res 81:370-80. 2009
    ..The present study was to determine whether visfatin is involved in these paracrine actions of PVAT, and if so, to explore the underlying mechanisms...
  41. doi request reprint A fluorometric assay for high-throughput screening targeting nicotinamide phosphoribosyltransferase
    Ruo Yu Zhang
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Anal Biochem 412:18-25. 2011
    ..This HTS system should expedite the discovery of Nampt inhibitors as antitumor drug candidates...
  42. doi request reprint Baroreflex deficiency hampers angiogenesis after myocardial infarction via acetylcholine-α7-nicotinic ACh receptor in rats
    Jian Guang Yu
    Department of Pharmacology, Second Military Medical University, 325 Guo He Road, Shanghai, China
    Eur Heart J 34:2412-20. 2013
    ..Human studies have associated arterial baroreflex (ABR) deficiency with higher rate of sudden death after MI. The present work was designed to examine whether ABR deficiency affects angiogenesis in MI rats...
  43. ncbi request reprint Acute pressure-natriuresis function shows early impairment in Lyon hypertensive rats
    Chao Yu Miao
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    J Hypertens 23:1225-31. 2005
    ....
  44. ncbi request reprint Reduction of blood pressure variability: a new strategy for the treatment of hypertension
    Ding feng Su
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Trends Pharmacol Sci 26:388-90. 2005
    ..The reduction of BPV is an important contributory factor of the organ protection provided by some antihypertensive drugs. Thus, reduction of BPV might represent a new strategy for the treatment of hypertension...
  45. ncbi request reprint Rapid inhibitory effect of glucocorticoids on airway smooth muscle contractions in guinea pigs
    Hai Wen Sun
    Laboratory of Stress Medicine, Department of Nautical Medicine, Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, PR China
    Steroids 71:154-9. 2006
    ..Further study can provide theoretical evidence for the clinical application of GCs in asthma and other allergic diseases...
  46. ncbi request reprint Greater hypertrophy in right than left ventricles is associated with pulmonary vasculopathy in sinoaortic-denervated Wistar-Kyoto rats
    Chao Yu Miao
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    Clin Exp Pharmacol Physiol 31:450-5. 2004
    ..5. These findings suggest that greater RVH following SAD is associated with pulmonary vasculopathy, but is not secondary to the left ventricular problems or high BPV...
  47. doi request reprint Protein tyrosine phosphatase 1B inhibits adipocyte differentiation and mediates TNFα action in obesity
    Dan Dan Song
    Department of Endocrinology, Second Military Medical University, Shanghai, China
    Biochim Biophys Acta 1831:1368-76. 2013
    ..Our study provides novel evidence for the importance of PTP1B in obesity and for the potential application of PTP1B inhibitors. ..
  48. doi request reprint A double-edged sword with therapeutic potential: an updated role of autophagy in ischemic cerebral injury
    Kai Wei
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    CNS Neurosci Ther 18:879-86. 2012
    ..Moreover, autophagy inhibitor abolished the neuroprotection of ischemic preconditioning, implying a neuroprotective effect of autophagy. To clarify these issues on autophagy in cerebral ischemia, future investigations are warranted...
  49. doi request reprint Visfatin and cardio-cerebro-vascular disease
    Pei Wang
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    J Cardiovasc Pharmacol 59:1-9. 2012
    ..This brief review focuses on the current understanding of the complex role of visfatin in the cardio-cerebro-vascular system under normal and pathophysiological conditions...
  50. doi request reprint Dexamethasone induces rapid promotion of norepinephrine‑mediated vascular smooth muscle cell contraction
    Ting Zhang
    Department of Nautical Medicine and Laboratory of Stress Medicine, Second Military Medical University, Shanghai 200433, P R China
    Mol Med Rep 7:549-54. 2013
    ....
  51. ncbi request reprint Reduction of blood pressure variability by combination therapy in spontaneously hypertensive rats
    He Hui Xie
    Department of Pharmacology, Second Military Medical University, Shanghai, China
    J Hypertens 25:2334-44. 2007
    ..To test the hypothesis that combination therapy might be a powerful tool to reduce blood pressure variability (BPV) in the treatment of hypertension...
  52. ncbi request reprint Hypertonic and isotonic potassium solutions have different effects on vessel contractility resulting in differences in optimal resting tension in rat aorta
    Yun Feng Guan
    Department of Pharmacology, Second Military Medical University, Shanghai 200433, China
    Acta Pharmacol Sin 28:643-50. 2007
    ..To compare high K(+ )-induced contraction and optimal resting tension measured by two commonly used techniques of hypertonic and isotonic K(+ ) in aortas with and without adventitial fat from various age rats...