Chen J, Su Q, Qin J, Zhou Y, Ruan H, Chen Z, et al
. Correlation of MCT1 and ABCC2 gene polymorphisms with valproic acid resistance in patients with epilepsy on valproic acid monotherapy. Drug Metab Pharmacokinet. 2018;: pubmed publisher
..Although the associations were abolished after Bonferroni correction, the results provide an incentive for further research in sufficiently large samples. ..
Wen D, Chen Z, Yang C, Liu H, Li H, Chen J, et al
. A rapid and simple HPLC-MS/MS method for the simultaneous quantification of valproic acid and its five metabolites in human plasma and application to study pharmacokinetic interaction in Chinese epilepsy patients. J Pharm Biomed Anal. 2018;149:448-456 pubmed publisher
..The result showed that there was no significant difference in the concentration of VPA and its five metabolites between patients in VPA monotherapy and patients in therapy combining VPA with LTG. ..