Hou R, Li M, Tang T, Wang R, Li Y, Xu Y, et al
. Construction of Lactobacillus casei ghosts by Holin-mediated inactivation and the potential as a safe and effective vehicle for the delivery of DNA vaccines. BMC Microbiol. 2018;18:80 pubmed publisher
..Our study constructed L. casei BGs by a novel method, which may be a promising technology for promoting the further application of DNA vaccine, providing experimental data to aid the development of other Gram-positive BGs. ..
Zhang X, Lan Y, Jiao W, Li Y, Tang L, Jiang Y, et al
. Isolation and Characterization of a Novel Virulent Phage of Lactobacillus casei ATCC 393. Food Environ Virol. 2015;7:333-41 pubmed publisher
..This study increased the knowledge on phages of L. casei. The characterization of phage Lcb is helpful to establish a basis for adopting effective strategies to control phage attack in industry. ..
Hou X, Jiang X, Jiang Y, Tang L, Xu Y, Qiao X, et al
. Oral Immunization against PEDV with Recombinant Lactobacillus casei Expressing Dendritic Cell-Targeting Peptide Fusing COE Protein of PEDV in Piglets. Viruses. 2018;10: pubmed publisher
..These results show that pPG-COE-DCpep/L393 is a potential vaccine against PEDV infection. ..
Zhao L, Guo Z, Liu J, Wang Z, Wang R, Li Y, et al
. Recombinant Lactobacillus casei expressing Clostridium perfringens toxoids Î±, Î²2, Îµ and Î²1 gives protection against Clostridium perfringens in rabbits. Vaccine. 2017;35:4010-4021 pubmed publisher
..casei 393 can eliciteffective immunoprotection against C. perfringens. All of these suggest that the use of pPG-2-Î±-Î²2-Îµ-Î²1/L. casei 393 can be regarded as candidate for the development of a vaccine against C. perfringens. ..
Yu M, Wang L, Ma S, Wang X, Wang Y, Xiao Y, et al
. Immunogenicity of eGFP-Marked Recombinant Lactobacillus casei against Transmissible Gastroenteritis Virus and Porcine Epidemic Diarrhea Virus. Viruses. 2017;9: pubmed publisher
..Our data suggest that the antibiotic resistance-free genetically engineered L. casei bivalent oral vaccine provides a safe and promising strategy for vaccine development against PEDV and TGEV. ..
Wang X, Wang L, Huang X, Ma S, Yu M, Shi W, et al
. Oral Delivery of Probiotics Expressing Dendritic Cell-Targeting Peptide Fused with Porcine Epidemic Diarrhea Virus COE Antigen: A Promising Vaccine Strategy against PEDV. Viruses. 2017;9: pubmed publisher
..This mucosal DC-targeting oral vaccine delivery effectively enhances vaccine antigen delivery efficiency, providing a useful strategy to induce efficient immune responses against PEDV infection. ..