Long Chuan Yu

Summary

Affiliation: Peking University
Country: China

Publications

  1. ncbi request reprint Effects of intrathecal galanin on nociceptive responses in rats with mononeuropathy
    L C Yu
    Department of Physiology, College of Life Science, Peking University, Beijing, China
    Life Sci 64:1145-53. 1999
  2. ncbi request reprint Involvement of calcitonin gene-related peptide and its receptor in anti-nociception in the periaqueductal grey of rats
    Long Chuan Yu
    Laboratory of Neurobiology, College of Life Sciences, National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, Beijing 100871, China
    Neurosci Lett 349:1-4. 2003
  3. doi request reprint Potential protection of curcumin against amyloid beta-induced toxicity on cultured rat prefrontal cortical neurons
    Xiao Yan Qin
    Laboratory of Biotechnology and State Key Laboratory of Chinese Ethnic Minority Traditional Medicine, College of Life and Environmental Science, Minzu University of China, Beijing 100081, China
    Neurosci Lett 463:158-61. 2009
  4. ncbi request reprint The effect of galanin on wide-dynamic range neuron activity in the spinal dorsal horn of rats
    L C Yu
    Department of Physiology, College of Life Sciences, and National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, 100871, Beijing, People s Republic of China
    Regul Pept 101:179-82. 2001
  5. doi request reprint Roles of calcitonin gene-related peptide and its receptors in pain-related behavioral responses in the central nervous system
    Long Chuan Yu
    Neurobiology Laboratory, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Neurosci Biobehav Rev 33:1185-91. 2009
  6. ncbi request reprint Calcitonin gene-related peptide 8-37 inhibits the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats
    L C Yu
    Department of Physiology, College of Life Science, Peking University, Beijing, People s Republic of China
    Regul Pept 83:21-4. 1999
  7. ncbi request reprint Involvement of neuropeptide Y and Y1 receptor in antinociception in the arcuate nucleus of hypothalamus, an immunohistochemical and pharmacological study in intact rats and rats with inflammation
    Jin ju Li
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Pain 118:232-42. 2005
  8. doi request reprint Galanin protects against intracellular amyloid toxicity in human primary neurons
    Jia Cui
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, China
    J Alzheimers Dis 19:529-44. 2010
  9. doi request reprint Involvement of opioid receptors in the CGRP-induced antinociception in the nucleus accumbens of rats
    Lixin Li
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane, Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Brain Res 1353:53-9. 2010
  10. ncbi request reprint Plastic changes of calcitonin gene-related peptide in morphine tolerance: behavioral and immunohistochemical study in rats
    Xiang Zhou
    College of Life Sciences, Center for Brain and Cognitive Science and National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, Beijing, People s Republic of China
    J Neurosci Res 74:622-9. 2003

Collaborators

Detail Information

Publications78

  1. ncbi request reprint Effects of intrathecal galanin on nociceptive responses in rats with mononeuropathy
    L C Yu
    Department of Physiology, College of Life Science, Peking University, Beijing, China
    Life Sci 64:1145-53. 1999
    ..The results indicate that galanin may play important roles in transmission of presumed nociceptive information in the spinal cord of mononeuropathic rats...
  2. ncbi request reprint Involvement of calcitonin gene-related peptide and its receptor in anti-nociception in the periaqueductal grey of rats
    Long Chuan Yu
    Laboratory of Neurobiology, College of Life Sciences, National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, Beijing 100871, China
    Neurosci Lett 349:1-4. 2003
    ..The results demonstrated that CGRP plays an important role in anti-nociception in PAG of rats, and CGRP1 receptor is involved in the CGRP-induced anti-nociception...
  3. doi request reprint Potential protection of curcumin against amyloid beta-induced toxicity on cultured rat prefrontal cortical neurons
    Xiao Yan Qin
    Laboratory of Biotechnology and State Key Laboratory of Chinese Ethnic Minority Traditional Medicine, College of Life and Environmental Science, Minzu University of China, Beijing 100081, China
    Neurosci Lett 463:158-61. 2009
    ..The results suggest that curcumin protects cultured rat primary prefrontal cortical neurons against Abeta-induced cytotoxicity, and both Bcl2 and caspase-3 are involved in the curcumin-induced protective effects...
  4. ncbi request reprint The effect of galanin on wide-dynamic range neuron activity in the spinal dorsal horn of rats
    L C Yu
    Department of Physiology, College of Life Sciences, and National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, 100871, Beijing, People s Republic of China
    Regul Pept 101:179-82. 2001
    ..The results suggest that galanin has an inhibitory role in the transmission of presumed nociceptive information in the dorsal horn of the spinal cord in rats...
  5. doi request reprint Roles of calcitonin gene-related peptide and its receptors in pain-related behavioral responses in the central nervous system
    Long Chuan Yu
    Neurobiology Laboratory, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Neurosci Biobehav Rev 33:1185-91. 2009
    ..The specific goal of this review is to summarize the roles of CGRP, CGRP8-37 and CGRP receptors in pain-related behavioral responses in the central nervous system...
  6. ncbi request reprint Calcitonin gene-related peptide 8-37 inhibits the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats
    L C Yu
    Department of Physiology, College of Life Science, Peking University, Beijing, People s Republic of China
    Regul Pept 83:21-4. 1999
    ..The results indicate that CGRP receptors play an important role in the transmission of presumed nociceptive information in the dorsal horn of the spinal cord...
  7. ncbi request reprint Involvement of neuropeptide Y and Y1 receptor in antinociception in the arcuate nucleus of hypothalamus, an immunohistochemical and pharmacological study in intact rats and rats with inflammation
    Jin ju Li
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Pain 118:232-42. 2005
    ..Both Y1 receptor and endogenous released NPY in the ARC are involved in the nociceptive modulation during inflammation...
  8. doi request reprint Galanin protects against intracellular amyloid toxicity in human primary neurons
    Jia Cui
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, China
    J Alzheimers Dis 19:529-44. 2010
    ..The galanin protection may be mediated by galanin receptor 2 and down-regulation of Bax level. The data from the present study provide a potential drug target for therapy or prevention of neurodegenerative diseases, including AD...
  9. doi request reprint Involvement of opioid receptors in the CGRP-induced antinociception in the nucleus accumbens of rats
    Lixin Li
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane, Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Brain Res 1353:53-9. 2010
    ..The results of the present study demonstrate that both mu- and kappa-opioid receptors are involved in the CGRP-induced antinociception in the NAc of rats...
  10. ncbi request reprint Plastic changes of calcitonin gene-related peptide in morphine tolerance: behavioral and immunohistochemical study in rats
    Xiang Zhou
    College of Life Sciences, Center for Brain and Cognitive Science and National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, Beijing, People s Republic of China
    J Neurosci Res 74:622-9. 2003
    ..The present study demonstrates plastic changes in both CGRP-induced antinociception and CGRP-like immunoreactivity in rat brain after morphine tolerance, suggesting that CGRP may play an important role in morphine tolerance...
  11. ncbi request reprint Antinociceptive role of galanin in the spinal cord of rats with inflammation, an involvement of opioid systems
    Wei Xiong
    Laboratory of Neurobiology and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Science, Peking University, Beijing 100871, China
    Regul Pept 132:85-90. 2005
    ..The results indicate that galanin plays an important role in the transmission of nociceptive information in the spinal cord of rats with inflammation, and opioid systems are involved in the galanin-induced antinociception...
  12. ncbi request reprint Involvement of opioid receptors in the CGRP8-37-induced inhibition of the activity of wide-dynamic-range neurons in the spinal dorsal horn of rats
    Yi Yan
    Laboratory of Neurobiology, College of Life Sciences, and National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, Beijing, Peoples Republic of China
    J Neurosci Res 77:148-52. 2004
    ..The results indicate that kappa- and mu-opioid receptors on the membrane of WDR neurons are involved in the modulation of CGRP8-37-induced antinociception in dorsal horn of the spinal cord in rats...
  13. ncbi request reprint The neural pathway of galanin in the hypothalamic arcuate nucleus of rats: activation of beta-endorphinergic neurons projecting to periaqueductal gray matter
    Yan Gang Sun
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, People s Republic of China
    J Neurosci Res 85:2400-6. 2007
    ..Taken together, our results suggest that galanin produces antinociceptive effects in the ARC of rats by activating the beta-endorphinergic pathway from ARC to PAG...
  14. ncbi request reprint Antinociceptive effects of galanin in the rat tuberomammillary nucleus and the plasticity of galanin receptor 1 during hyperalgesia
    Yan Gang Sun
    Department of Physiology, College of Life Sciences, National Laboratory of Biomembrane and Membrane Biotechnology and Center for Brain and Cognitive Science, Peking University, Beijing, People s Republic of China
    J Neurosci Res 77:718-22. 2004
    ..The results suggest that galanin and GalR1 in the TM may play important roles in pain regulation...
  15. doi request reprint Prolonged morphine application modulates Bax and Hsp70 levels in primary rat neurons
    Qiuyue Chen
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, China
    Neurosci Lett 441:311-4. 2008
    ..Morphine treatment decreases Bax and Hsp70 levels in cultured rat primary neurons, suggesting morphine may have a protective role in staurosporine and serum deprivation induced cytotoxicity...
  16. ncbi request reprint Anti-nociceptive effect of neuropeptide Y in the nucleus accumbens of rats: an involvement of opioid receptors in the effect
    Ying Li
    Department of Physiology, College of Life Science, Peking University, 100871, Beijing, China
    Brain Res 940:69-78. 2002
    ....
  17. doi request reprint Antinociceptive effects of galanin in the central nucleus of amygdala of rats, an involvement of opioid receptors
    Wu Yang Jin
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Brain Res 1320:16-21. 2010
    ..Taken together, the results demonstrate that galanin induces antinociceptive effects in the CeA of rats, and both mu- and delta-opioid receptors are involved in the galanin-induced antinociception...
  18. ncbi request reprint Involvement of opioid receptors in oxytocin-induced antinociception in the nucleus accumbens of rats
    Xing Long Gu
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, China
    J Pain 8:85-90. 2007
    ....
  19. ncbi request reprint It is AMPA receptor, not kainate receptor, that contributes to the NBQX-induced antinociception in the spinal cord of rats
    Ling Ling Kong
    Laboratory of Neurobiology and National Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Brain Res 1100:73-7. 2006
    ..The results suggest that the NBQX-induced antinociception was mediated by AMPA receptors, not by kainate receptors, in the spinal cord of rats...
  20. ncbi request reprint Role of corticotropin-releasing factor and its receptor in nociceptive modulation in the central nucleus of amygdala in rats
    Xi Yun Cui
    Laboratory Neurobiology, Department of Physiology, College of Life Sciences, and National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, Beijing 100871, PR China
    Brain Res 995:23-8. 2004
    ..The present study demonstrated that both exogenous and endogenous CRF plays an antinociceptive effect in the CeA, the effect is mediated by CRF receptor...
  21. ncbi request reprint An antinociceptive role of galanin in the arcuate nucleus of hypothalamus in intact rats and rats with inflammation
    Yan Gang Sun
    Neurobiology Laboratory, College of Life Sciences, National Laboratory of Biomembrane and Membrane Biotechnology and Center for Brain and Cognitive Science, Peking University, Beijing 100871, China
    Pain 106:143-50. 2003
    ..Taken together, the results show that galanin has an antinociceptive role in the ARC of intact rats and rats with inflammation...
  22. ncbi request reprint Interactions of galanin and opioids in nociceptive modulation in the arcuate nucleus of hypothalamus in rats
    Yan Gang Sun
    Department of Physiology, College of Life Sciences, National Laboratory of Biomembrane and Membrane Biotechnology, Center for Brain and Cognitive Science, Peking University, Beijing 100871, People s Republic of China
    Regul Pept 124:37-43. 2005
    ..These results demonstrate that the antinociceptive effect of galanin was related to the opioid system, especially mu-opioid receptor was involved in, and that systemic morphine induced antinociception involves galanin in the ARC...
  23. ncbi request reprint Antinociceptive effects induced by injection of the galanin receptor 1 agonist M617 into central nucleus of amygdala in rats
    Jun Li
    State Key Laboratory of Biomembrane and Membrane, Biotechnology and Neurobiology Laboratory, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 526:45-8. 2012
    ..The results demonstrated that intra-CeA injection of M617 induced significant antinociceptive effects in CeA of rats, indicating that galanin receptor 1 may be involved in M617-induced antinociception in the CeA of rats...
  24. doi request reprint Galanin protects amyloid-beta-induced neurotoxicity on primary cultured hippocampal neurons of rats
    Yong Cheng
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, People s Republic of China
    J Alzheimers Dis 20:1143-57. 2010
    ..Our results strongly demonstrate that galanin plays neuroprotective roles in nerve cells and in AD-induced learning and memory deficits...
  25. ncbi request reprint The colocalization of CGRP receptor and AMPA receptor in the spinal dorsal horn neuron of rat: a morphological and electrophysiological study
    Xing Long Gu
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 414:237-41. 2007
    ....
  26. ncbi request reprint Involvement of mu- and delta-opioid receptors in the antinociceptive effects induced by AMPA receptor antagonist in the spinal cord of rats
    Ling Ling Kong
    Laboratory of Neurobiology and National Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 402:180-3. 2006
    ..The results suggest that mu- and delta-opioid receptors, not kappa-opioid receptor, are involved in the antinociception induced by AMPA antagonist in the spinal cord of rats...
  27. ncbi request reprint Alternation of galanin in nociceptive modulation in the central nervous system of rats during morphine tolerance: a behavioral and immunohistochemical study
    Xia Wu
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, 100871, PR China
    Brain Res 1086:85-91. 2006
    ..The results suggest an involvement of galanin in the central nervous system in morphine tolerance...
  28. ncbi request reprint Antinociceptive role of oxytocin in the nucleus raphe magnus of rats, an involvement of mu-opioid receptor
    Jing Wen Wang
    Laboratory of Neurobiology, College of Life Sciences, Peking University, Beijing 100871, China
    Regul Pept 115:153-9. 2003
    ..Moreover, mu-opioid receptors, not kappa and delta receptors, are involved in the oxytocin-induced antinociception in the NRM of rats...
  29. ncbi request reprint Involvements of mu- and kappa-opioid receptors in morphine-induced antinociception in the nucleus accumbens of rats
    Wei Xiong
    Laboratory of Neurobiology and The National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Science, Peking University, Beijing 100871, China
    Neurosci Lett 399:167-70. 2006
    ..The results indicate that MOR and KOR, but not DOR are involved in the morphine-induced antinociception in the NAc of rats...
  30. doi request reprint Antinociceptive effects of galanin in the nucleus accumbens of rats
    Shi Lian Xu
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 520:43-6. 2012
    ..The results demonstrate that galanin induces antinociceptive effects in the NAc of rats, and galanin receptors are involved in the galanin-induced antinociception effects...
  31. ncbi request reprint Role of calcitonin gene-related peptide and its antagonist on the evoked discharge frequency of wide dynamic range neurons in the dorsal horn of the spinal cord in rats
    Yi Yu
    Department of Physiology, College of Life Sciences, Peking University, 100871, Beijing, People s Republic of China
    Regul Pept 103:23-7. 2002
    ..The results indicate that CGRP and its receptors play a facilitary role on the transmission and/or modulation of nociceptive information in the dorsal horn of the spinal cord in rats...
  32. doi request reprint Antinociceptive effects induced by intra-periaqueductal grey injection of the galanin receptor 1 agonist M617 in rats with morphine tolerance
    Qingyao Kong
    Neurobiology Laboratory, School of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 550:125-8. 2013
    ....
  33. ncbi request reprint Involvement of endogenous beta-endorphin in antinociception in the arcuate nucleus of hypothalamus in rats with inflammation
    Yan Gang Sun
    Department of Physiology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Pain 104:55-63. 2003
    ..The results indicate that endogenous beta-endorphin in the ARC plays an important role in the endogenous antinociceptive system in rats with inflammation, and that its effect is predominantly mediated by the mu-opioid receptor...
  34. ncbi request reprint Increases in ╬▒CaMKII phosphorylated on Thr286 in the nucleus accumbens shell but not the core during priming-induced reinstatement of morphine-seeking in rats
    Zhuo Liu
    State Key Laboratory of Biomembrane and Membrane Biotechnology, and Laboratory of Neurobiology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Neurosci Lett 526:39-44. 2012
    ....
  35. doi request reprint Inhibition of CaMKII activity in the nucleus accumbens shell blocks the reinstatement of morphine-seeking behavior in rats
    Zhuo Liu
    Laboratory of Neurobiology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Neurosci Lett 518:167-71. 2012
    ..Our results strongly indicate that CaMKII activity in the NAc shell is essential to the relapse to morphine-seeking...
  36. doi request reprint Potential protection of curcumin against intracellular amyloid beta-induced toxicity in cultured rat prefrontal cortical neurons
    Xiao Yan Qin
    Laboratory of Biotechnology and State Key Laboratory of Chinese Ethnic Minority Traditional Medicine, College of Life and Environmental Science, Minzu University of China, Beijing, 100081, China
    Neurosci Lett 480:21-4. 2010
    ..The results suggest that curcumin may play a protective effect in primary cultured rat prefrontal cortical neurons against iAbeta-induced cytotoxicity, and both AKT and caspase-3 are involved in the curcumin-induced protective effects...
  37. doi request reprint Different physiological properties of spontaneous excitatory postsynaptic currents in nucleus accumbens shell neurons between adult and juvenile rats
    Xiao Dong Liu
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, People s Republic of China
    Neurosci Lett 496:80-3. 2011
    ..The above results strongly indicate that there are marked changes in the electrophysiological properties of single sEPSC in the NAcS slices of juvenile and adult rats...
  38. ncbi request reprint Anti-nociceptive effects of diazepam binding inhibitor in the central nervous system of rats
    Wei Wang
    Department of Physiology, College of Life Science, National Laboratory of Biomembrane and Membrane Biotechnology and Center for Brain and Cognitive Science, Peking University, Beijing 100871, PR China
    Brain Res 956:393-7. 2002
    ..The results of the present study demonstrated that DBI played anti-nociceptive effects in the central nervous system of rats...
  39. ncbi request reprint Involvement of galanin in nociceptive regulation in the arcuate nucleus of hypothalamus in rats with mononeuropathy
    Xing Long Gu
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, Center for Brain and Cognitive Science, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Behav Brain Res 179:331-5. 2007
    ..The results demonstrated that both endogenous and exogenous galanin were involved in the regulation of nociception in the ARC of rats with peripheral nerve injury...
  40. ncbi request reprint Blockade effect of mu and kappa opioid antagonists on the anti-nociception induced by intra-periaqueductal grey injection of oxytocin in rats
    Yuan Ge
    Department of Physiology, College of Life Sciences, and Center for Brain and Cognitive Science, Peking University, Beijing 100871, People s Republic of China
    Brain Res 927:204-7. 2002
    ..The results demonstrated that mu and kappa opioid receptors, not delta receptors, were involved in the oxytocin-induced anti-nociception in PAG of rats...
  41. doi request reprint Potential protection of green tea polyphenols against intracellular amyloid beta-induced toxicity on primary cultured prefrontal cortical neurons of rats
    Xiao Yan Qin
    Laboratory of Biotechnology and State Key Laboratory of Chinese Ethnic Minority Traditional Medicine, College of Life and Environmental Science, Minzu University of China, Beijing 100081, China
    Neurosci Lett 513:170-3. 2012
    ....
  42. doi request reprint Changes of protein expression profiles in the amygdala during the process of morphine-induced conditioned place preference in rats
    Xiaojing Lin
    Laboratory of Neurobiology and the State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, China
    Behav Brain Res 221:197-206. 2011
    ..Our results provide some proteins and cellular signaling pathways involved in the molecular mechanisms of opioid addiction in amygdala...
  43. doi request reprint Blockade effects of BIBN4096BS on CGRP-induced inhibition on whole-cell K+ currents in spinal dorsal horn neuron of rats
    Jun Feng Hou
    Laboratory of Neurobiology and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Neurosci Lett 469:15-8. 2010
    ..The results indicate that BIBN4096BS may produce antinociceptive effects at the spinal level in rats...
  44. ncbi request reprint Chronic morphine application is protective against cell death in primary human neurons
    Jia Cui
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, China
    Neuroreport 19:1745-9. 2008
    ..In addition, heat shock protein 70 is also involved in morphine protection. Our data suggest that chronic morphine application may be beneficial to stimulate cell survival...
  45. ncbi request reprint Alterations in the substance P-induced anti-nociception in the central nervous system of rats after morphine tolerance
    Xiao Guo Dong
    Laboratory of Neurobiology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 381:47-50. 2005
    ....
  46. ncbi request reprint Involvement of endogenous cholecystokinin in tolerance to morphine antinociception in the nucleus accumbens of rats
    Wei Xiong
    Laboratory of Neurobiology and The National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Science, Peking University, Beijing 100871, China
    Behav Brain Res 173:116-21. 2006
    ..The results indicate that endogenous CCK plays an important role in morphine-induced antinociceptive tolerance in the NAc of rats...
  47. ncbi request reprint Roles of oxytocin in spatial learning and memory in the nucleus basalis of Meynert in rats
    Wei Wu
    Laboratory of Neurobiology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Regul Pept 120:119-25. 2004
    ..Moreover, there were no influences of OT or Atosiban on the retention performance in rats. The results suggest that OT plays an inhibitory role in spatial learning in the NBM; the effect is mediated by OT receptor...
  48. doi request reprint Influences of calcitonin gene-related peptide on mu opioid receptors in nucleus accumbens neurons of rats
    Hailiang Yan
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neuropeptides 47:125-31. 2013
    ..To conclude, these results demonstrate that CGRP can act on MORs and increase the number of surface MORs in NAc neurons, partially explaining the involvement of opioid receptors in CGRP-induced antinociception in the rat NAc...
  49. pmc Involvement of protein kinase C in morphine tolerance at spinal levels of rats
    Wu Yang Jin
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    ACS Chem Neurosci 1:122-8. 2010
    ....
  50. doi request reprint Role of MEK-ERK pathway in morphine-induced conditioned place preference in ventral tegmental area of rats
    Xiaojing Lin
    The National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing, China
    J Neurosci Res 88:1595-604. 2010
    ..The present study found significant changes in a group of protein expressions in VTA during morphine-induced CPP and further confirmed the role of MEK-ERK cell signaling pathway of VTA in morphine addiction...
  51. ncbi request reprint Involvement of oxytocin in spinal antinociception in rats with inflammation
    Shuang Quan Yu
    Neurobiology Laboratory, College of Life Sciences, and Center for Brain and Cognitive Science and National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, 100871, Beijing, China
    Brain Res 983:13-22. 2003
    ..The present study showed that both exogenous and endogenous oxytocin displayed antinociception in the spinal cord in rats with inflammation, and mu- and kappa-receptors were involved in oxytocin-induced antinociception...
  52. ncbi request reprint Anti-nociceptive effect induced by intrathecal injection of ATPA, an effect enhanced and prolonged by concanavalin A
    Dong Chuan Wu
    Department of Physiology, College of Life Sciences, Peking University, Beijing 100871, China
    Brain Res 959:275-9. 2003
    ..Furthermore, blocking the desensitization of kainate receptor enhanced and prolonged the ATPA-induced anti-nociceptive effects...
  53. ncbi request reprint Role of nociceptin in the modulation of nociception in the arcuate nucleus of rats
    Ning Li
    Laboratory of Neurobiology, College of Life Sciences, Peking University, Beijing 100871, P R China
    Brain Res 1025:67-74. 2004
    ..The present study also demonstrates an interaction between nociceptin and opioids in the arcuate nucleus of the hypothalamus...
  54. ncbi request reprint Involvement of opioid receptors in the oxytocin-induced antinociception in the central nervous system of rats
    Lian Gao
    Laboratory of Neurobiology, College of Life Sciences, and National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, Beijing 100871, PR China
    Regul Pept 120:53-8. 2004
    ..The results indicate that oxytocin plays an antinociceptive role in the brain of rats; mu- and kappa-opioid receptors, not delta-receptors, are involved in the oxytocin-induced antinociception in the central nervous system of rats...
  55. ncbi request reprint Intracellular amyloid induces impairments on electrophysiological properties of cultured human neurons
    Jun Feng Hou
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, China
    Neurosci Lett 462:294-9. 2009
    ..These results suggest the electrophysiological impairments induced by iAbeta may be responsible for its neuronal toxicity...
  56. doi request reprint Expression of calcitonin gene-related peptide receptor subunits in cultured neurons following morphine treatment
    Hailiang Yan
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 544:52-5. 2013
    ....
  57. doi request reprint Post-retrieval extinction training enhances or hinders the extinction of morphine-induced conditioned place preference in rats dependent on the retrieval-extinction interval
    Xiang Ma
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Psychopharmacology (Berl) 221:19-26. 2012
    ..To confirm the erasure hypothesis, in addition to the conventional spontaneous recovery and reinstatement assays, we conduct further assessment to detect the existence of drug-associated memories...
  58. doi request reprint Repeated paired-testing impairs extinction of morphine-induced conditioned place preference dependent on the inter-test interval in rats
    Jian Jun Zhang
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 516:72-4. 2012
    ..These results strongly indicate that the interval between exposure trials influences the outcome of exposure therapy in addiction treatment...
  59. doi request reprint Involvement of protein kinase C in the galanin-induced antinociception in the brain of rats
    Jiao Shi
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 497:60-3. 2011
    ..Taken together, the results demonstrate that galanin induces antinociceptive effects in the rat brain, and PKC is involved in the galanin-induced antinociception in the brain of rats...
  60. ncbi request reprint The role of intracellular amyloid beta in Alzheimer's disease
    Meng Li
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, China
    Prog Neurobiol 83:131-9. 2007
    ..Therapeutics targeting intracellular Abeta could be effective treatment for AD...
  61. doi request reprint Inhibitory effects of calcitonin gene-related peptide on long-term potentiation induced in hippocampal slices of rats
    Xiao Dong Liu
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Neurosci Lett 494:10-3. 2011
    ..The inhibitory effect was blocked by CGRP receptor-1 antagonist CGRP 8-37. The results indicate that both CGRP and CGRP receptor 1 are involved in the modulation process of LTP in hippocampus of rats...
  62. doi request reprint Single-cell microinjection technology in cell biology
    Yan Zhang
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, China
    Bioessays 30:606-10. 2008
    ..This review discusses the advantages and limits of microinjection as a mechanical delivery method and its applications to attached and suspended cells...
  63. ncbi request reprint Blockade effects of (Nphe1)Nociceptin(1-13)-NH(2) on anti-nociception induced by intrathecal administration of nociceptin in rats
    J T Lu
    Department of Physiology, College of Life Sciences, Peking University, 100871, Beijing, China
    Regul Pept 101:81-5. 2001
    ..The results demonstrated that ORL1 receptor is involved in the nociceptin-induced anti-nociceptive effect in the spinal cord of rats...
  64. ncbi request reprint Involvement of CGRP and CGRP1 receptor in nociception in the nucleus accumbens of rats
    N Li
    Department of Physiology, College of Life Science, and National Laboratory of Biomembrane and Membrane Biotechnology, Peking University, 100871, Beijing, People's Republic of China
    Brain Res 901:161-6. 2001
    ..The results indicate that CGRP and CGRP1 receptor have important roles in nociceptive modulation in the nucleus accumbens of rats...
  65. doi request reprint Involvement of oxytocin and its receptor in nociceptive modulation in the central nucleus of amygdala of rats
    Yi Han
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Neurosci Lett 454:101-4. 2009
    ..The present study demonstrated that oxytocin and its receptors are involved in nociceptive modulation in the CeA of rats...
  66. doi request reprint Potential protection of green tea polyphenols against ultraviolet irradiation-induced injury on rat cortical neurons
    Mei Li Liu
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, China
    Neurosci Lett 444:236-9. 2008
    ..Our results demonstrated that the green tea polyphenols inhibited the active Bax expression, suggesting a neuroprotective effect of green tea polyphenols against the UV-C light irradiation-induced injury on cortical neurons...
  67. doi request reprint Antinociceptive effects of intracerebroventricular injection of the galanin receptor 1 agonist M 617 in rats
    Li Bo Fu
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane, Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 491:174-6. 2011
    ..Interestingly, there were no significant differences between the antinociceptive effects induced by M 617 and galanin, indicating that galanin receptor 1 plays main roles in galanin-induced antinociceptive effects in the brain of rats...
  68. doi request reprint Potential protection of curcumin against hypoxia-induced decreases in beta-III tubulin content in rat prefrontal cortical neurons
    Yu Shen
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, People s Republic of China
    Neurochem Res 33:2112-7. 2008
    ....
  69. doi request reprint Morphine: a protective or destructive role in neurons?
    Yan Zhang
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology College of Life Sciences, Peking University, Beijing, China
    Neuroscientist 14:561-70. 2008
    ....
  70. ncbi request reprint Valproic acid sodium inhibits the morphine-induced conditioned place preference in the central nervous system of rats
    Ping Mu
    Neurobiology Laboratory and National Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 426:135-8. 2007
    ..c.v. injection, but also suggest that the antiepileptic drug VPA may be utilized as potential therapeutic medications for drug abuse in the future...
  71. ncbi request reprint Anti-nociceptive effect of neuropeptide Y in periaqueductal grey in rats with inflammation
    J Z Wang
    Department of Physiology, College of Life Science, Peking University, Beijing, People's Republic of China
    Brain Res 893:264-7. 2001
    ..The results demonstrated that NPY plays an anti-nociceptive role in PAG in rats with inflammation, in which Y1 receptor is involved...
  72. doi request reprint Distinct mechanisms mediate the reinstatement and spontaneous recovery of extinguished fear in rats
    Xiang Ma
    Neurobiology Laboratory and State Key Laboratory of Biomembrane and Membrane, Biotechnology, College of Life Sciences, Peking University, Beijing 100871, PR China
    Neurosci Lett 510:34-7. 2012
    ..These results implicated that return of fear in two conventional assays after extinction, i.e., reinstatement assay and spontaneous recovery assay, are mediated by different mechanisms...
  73. doi request reprint Receptor trafficking induced by mu-opioid-receptor phosphorylation
    Yan Zhang
    Laboratory of Neurobiology, College of Life Sciences, Peking University, Beijing 100871, China
    Neurosci Biobehav Rev 33:1192-7. 2009
    ..Also, the role of G-protein coupled receptor kinases in opioid-receptor phosphorylation is discussed. How to associate these observations to physiological and behavioral changes in animal models and clinics is still under investigation...
  74. doi request reprint Microinjection as a tool of mechanical delivery
    Yan Zhang
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, China
    Curr Opin Biotechnol 19:506-10. 2008
    ....
  75. ncbi request reprint Substance P microinjected into the periaqueductal gray matter induces antinociception and is released following morphine administration
    Annika Rosen
    Department of Odontology, Division of Oral and Maxillofacial Surgery, Karolinska Institutet, Huddinge Hospital, Box 4064, SE 141 04 Huddinge, Sweden
    Brain Res 1001:87-94. 2004
    ..Morphine administered systemically induces the release of SP in the ventrolateral PAG. We suggest that an increased release of SP in the PAG may contribute to opioid antinociception...
  76. ncbi request reprint Repeated massage-like stimulation induces long-term effects on nociception: contribution of oxytocinergic mechanisms
    Irene Lund
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Eur J Neurosci 16:330-8. 2002
    ..The long-term antinociceptive effects of massage-like stroking may be attributed, at least partly, to the oxytocinergic system and its interaction with the opioid system, especially the mu- and the kappa-receptors in the PAG...
  77. ncbi request reprint Involvement of endogenous opioid systems in nociceptin-induced spinal antinociception in rats
    Long Chuan Yu
    Department of Anesthesia and Perioperative Care, University of California, Box 0464, Room S 455 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Brain Res 945:88-96. 2002
    ..Since it is unlikely that nociceptin acts by direct binding to opioid receptors, these results suggest a possible interaction between the nociceptin/ORL1 and opioid systems in the dorsal horn of the rat spinal cord...
  78. ncbi request reprint [Progresses in the study of corticotropin releasing factor (CRF) and CRF receptor, their roles in the regulation of pain]
    Xi Yun Cui
    Sheng Li Ke Xue Jin Zhan 34:263-5. 2003