Guo Gang Xing

Summary

Affiliation: Peking University
Country: China

Publications

  1. pmc The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant
    Lu Yu
    Neuroscience Research Institute, School of Basic Medical Sciences, Peking University, Beijing, PR China
    Mol Pain 4:61. 2008
  2. ncbi request reprint Long-term synaptic plasticity in the spinal dorsal horn and its modulation by electroacupuncture in rats with neuropathic pain
    Guo Gang Xing
    Department of Neurobiology, Key Laboratory for Neuroscience of the Ministry of Education and Public Health, Peking University, 38 Xue Yuan Road, Beijing 100083, People s Republic of China
    Exp Neurol 208:323-32. 2007
  3. doi request reprint Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation
    Shan Jing Geng
    Neuroscience Research Institute and Department of Neurobiology, Peking University, 38 Xue Yuan Road, Beijing 100191, PR China
    Exp Neurol 222:256-66. 2010
  4. doi request reprint Decrease in the descending inhibitory 5-HT system in rats with spinal nerve ligation
    Feng Yu Liu
    Neuroscience Research Institute and Department of Neurobiology, Peking University, 38 Xue Yuan Road, Beijing 100191, PR China
    Brain Res 1330:45-60. 2010
  5. ncbi request reprint Inhibition of hyperpolarization-activated current by ZD7288 suppresses ectopic discharges of injured dorsal root ganglion neurons in a rat model of neuropathic pain
    Qian Sun
    Neuroscience Research Institute, Peking University, Key Laboratory of Neuroscience, Ministry of Education, 38 Xueyuan Road, Beijing 100083, China
    Brain Res 1032:63-9. 2005
  6. doi request reprint Role of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit GluR1 in spinal dorsal horn in inflammatory nociception and neuropathic nociception in rat
    Yue Lu
    Neuroscience Research Institute, Peking University, 38 Xueyuan Road, Beijing 100083, China
    Brain Res 1200:19-26. 2008
  7. ncbi request reprint Ectopic discharges from injured nerve fibers are highly correlated with tactile allodynia only in early, but not late, stage in rats with spinal nerve ligation
    Qian Sun
    Neuroscience Research Institute, Peking University, Key Laboratory of Neuroscience, Ministry of Education, Beijing 100083, China
    Exp Neurol 191:128-36. 2005
  8. ncbi request reprint Roles of 5-hydroxytryptamine (5-HT) receptor subtypes in the inhibitory effects of 5-HT on C-fiber responses of spinal wide dynamic range neurons in rats
    Feng Yu Liu
    Neuroscience Research Institute and Department of Neurobiology, Peking University, Key Laboratory for Neuroscience, Ministry of Education, Beijing, People s Republic of China
    J Pharmacol Exp Ther 321:1046-53. 2007
  9. doi request reprint Electrophysiological properties of spinal wide dynamic range neurons in neuropathic pain rats following spinal nerve ligation
    Feng Yu Liu
    Neuroscience Research Institute, Peking University, Beijing 100191, China
    Neurosci Bull 27:1-8. 2011
  10. doi request reprint Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain
    Xiao Xiu Qu
    Neuroscience Research Institute and Department of Neurobiology, Peking University, 38 Xue Yuan Road, Beijing 100191, PR China
    Exp Neurol 215:298-307. 2009

Collaborators

Detail Information

Publications20

  1. pmc The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant
    Lu Yu
    Neuroscience Research Institute, School of Basic Medical Sciences, Peking University, Beijing, PR China
    Mol Pain 4:61. 2008
    ..Chronic inflammatory nociception of rats was produced by intraplantar injection of complete Freund's adjuvant (CFA) and data was collected until day 28 following injection...
  2. ncbi request reprint Long-term synaptic plasticity in the spinal dorsal horn and its modulation by electroacupuncture in rats with neuropathic pain
    Guo Gang Xing
    Department of Neurobiology, Key Laboratory for Neuroscience of the Ministry of Education and Public Health, Peking University, 38 Xue Yuan Road, Beijing 100083, People s Republic of China
    Exp Neurol 208:323-32. 2007
    ..LTD of synaptic strength in the spinal dorsal horn in SNL rats may contribute to the long-lasting analgesic effects of EA at 2 Hz...
  3. doi request reprint Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation
    Shan Jing Geng
    Neuroscience Research Institute and Department of Neurobiology, Peking University, 38 Xue Yuan Road, Beijing 100191, PR China
    Exp Neurol 222:256-66. 2010
    ..These data suggested that the BDNF/TrkB-mediated signaling pathway in the spinal cord was involved in the development of nerve injury-induced neuropathic pain through the activation of dorsal horn NMDA-2B receptors...
  4. doi request reprint Decrease in the descending inhibitory 5-HT system in rats with spinal nerve ligation
    Feng Yu Liu
    Neuroscience Research Institute and Department of Neurobiology, Peking University, 38 Xue Yuan Road, Beijing 100191, PR China
    Brain Res 1330:45-60. 2010
    ....
  5. ncbi request reprint Inhibition of hyperpolarization-activated current by ZD7288 suppresses ectopic discharges of injured dorsal root ganglion neurons in a rat model of neuropathic pain
    Qian Sun
    Neuroscience Research Institute, Peking University, Key Laboratory of Neuroscience, Ministry of Education, 38 Xueyuan Road, Beijing 100083, China
    Brain Res 1032:63-9. 2005
    ..These results indicate that I(h) might play a role in the generation of various forms of ectopic discharges in the injured DRG neurons and may thus be a possible target for neuropathic pain treatment...
  6. doi request reprint Role of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit GluR1 in spinal dorsal horn in inflammatory nociception and neuropathic nociception in rat
    Yue Lu
    Neuroscience Research Institute, Peking University, 38 Xueyuan Road, Beijing 100083, China
    Brain Res 1200:19-26. 2008
    ..These results suggest that phosphorylated GluR1 (pGluR1-Ser845 and pGluR1-Ser831) might play a role in the induction of inflammatory but not neuropathic pain...
  7. ncbi request reprint Ectopic discharges from injured nerve fibers are highly correlated with tactile allodynia only in early, but not late, stage in rats with spinal nerve ligation
    Qian Sun
    Neuroscience Research Institute, Peking University, Key Laboratory of Neuroscience, Ministry of Education, Beijing 100083, China
    Exp Neurol 191:128-36. 2005
    ..These findings suggest that ectopic discharges may be crucial in the triggering of neuropathic pain in the early stage, but their importance become more limited over time...
  8. ncbi request reprint Roles of 5-hydroxytryptamine (5-HT) receptor subtypes in the inhibitory effects of 5-HT on C-fiber responses of spinal wide dynamic range neurons in rats
    Feng Yu Liu
    Neuroscience Research Institute and Department of Neurobiology, Peking University, Key Laboratory for Neuroscience, Ministry of Education, Beijing, People s Republic of China
    J Pharmacol Exp Ther 321:1046-53. 2007
    ....
  9. doi request reprint Electrophysiological properties of spinal wide dynamic range neurons in neuropathic pain rats following spinal nerve ligation
    Feng Yu Liu
    Neuroscience Research Institute, Peking University, Beijing 100191, China
    Neurosci Bull 27:1-8. 2011
    ....
  10. doi request reprint Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain
    Xiao Xiu Qu
    Neuroscience Research Institute and Department of Neurobiology, Peking University, 38 Xue Yuan Road, Beijing 100191, PR China
    Exp Neurol 215:298-307. 2009
    ..Therefore, the spinal cord NMDA-2B receptor is likely to be a target for clinical pain therapy...
  11. doi request reprint Axonal accumulation of hyperpolarization-activated cyclic nucleotide-gated cation channels contributes to mechanical allodynia after peripheral nerve injury in rat
    Yu Qiu Jiang
    Neuroscience Research Institute, Peking University, Beijing 100083, China
    Pain 137:495-506. 2008
    ..These results suggest that axonal HCN channel accumulation plays an important role in ectopic discharges from injured spinal nerves and contributes to the development of mechanical allodynia in neuropathic pain rats...
  12. pmc Enhanced excitability of small dorsal root ganglion neurons in rats with bone cancer pain
    Qin Zheng
    Neuroscience Research Institute and Department of Neurobiology, Peking University, 38 Xue Yuan Road, Beijing 100191, People s Republic of China
    Mol Pain 8:24. 2012
    ....
  13. doi request reprint Phase-amplitude coupling between θ and γ oscillations during nociception in rat electroencephalography
    Jing Wang
    Neuroscience Research Institute, Department of Neurobiology, Peking University, Beijing 100191, China
    Neurosci Lett 499:84-7. 2011
    ..Our results for the first time suggest that coupling between theta and gamma is involved in nociception processing...
  14. doi request reprint Activation of satellite glial cells in lumbar dorsal root ganglia contributes to neuropathic pain after spinal nerve ligation
    Feng Yu Liu
    Neuroscience Research Institute, Peking University, Beijing 100191, PR China
    Brain Res 1427:65-77. 2012
    ..These results suggest that SGCs in the DRG were activated after SNL. SGC activation contributed to the early maintenance of neuropathic pain...
  15. doi request reprint Behavioral and electrophysiological evidence for the differential functions of TRPV1 at early and late stages of chronic inflammatory nociception in rats
    Hao Luo
    Neuroscience Research Institute, Peking University, 38 Xueyuan Road, Beijing 100083, China
    Neurochem Res 33:2151-8. 2008
    ..These results provide new evidence for the functional significance of TRPV1 at the early stage, but not the late stage, in the rat model of CFA-induced inflammatory pain...
  16. pmc Anterior cingulate cortex is crucial for contra- but not ipsi-lateral electro-acupuncture in the formalin-induced inflammatory pain model of rats
    Ming Yi
    Neuroscience Research Institute, Peking University, 38 Xueyuan Road, Beijing 100191, China
    Mol Pain 7:61. 2011
    ..Overall, these results demonstrated distinct anti-nociceptive effects and mechanisms between different stimulating sides and implied the necessity of finding the best stimulating protocols for different pain states...
  17. doi request reprint Formaldehyde up-regulates TRPV1 through MAPK and PI3K signaling pathways in a rat model of bone cancer pain
    Ying Han
    Neuroscience Research Institute, the Ministry of Education the Ministry of Health, Peking University, Beijing 100191, China
    Neurosci Bull 28:165-72. 2012
    ....
  18. doi request reprint Down-regulation of CatSper1 channel in epididymal spermatozoa contributes to the pathogenesis of asthenozoospermia, whereas up-regulation of the channel by Sheng-Jing-San treatment improves the sperm motility of asthenozoospermia in rats
    Ya nan Wang
    Neuroscience Research Institute and Department of Neurobiology, Peking University, Beijing, People s Republic of China
    Fertil Steril 99:579-87. 2013
    ....
  19. ncbi request reprint The Neuroscience Research Institute at Peking University: a place for the solution of pain and drug abuse
    Albert C H Yu
    Neuroscience Research Institute, Peking University, 38 Xue Yuan Road, Beijing, 100083, China
    Cell Mol Neurobiol 28:13-9. 2008
    ..The institute is simultaneously investigating both theoretical and clinical studies. Acupuncture remains the core of research, while pain and drug abuse form the two disciplines...
  20. ncbi request reprint Postnatal switching of NMDA receptor subunits from NR2B to NR2A in rat facial motor neurons
    Guo Gang Xing
    Center for Neuroscience and Ageing, Burnham Institute for Medical Research, La Jolla, California 92037, USA
    Eur J Neurosci 24:2987-92. 2006
    ..Thus, analysis of functional NMDA receptors is critical to revealing subunit switching, which may be an important step in postnatal development of FN motor neurons...