Jinhua Wen

Summary

Affiliation: Peking University
Country: China

Publications

  1. doi request reprint Pax6 directly modulate Sox2 expression in the neural progenitor cells
    Jinhua Wen
    Peking University Stem Cell Research Center and Cell Biology Department, Peking University Health Science Center, Beijing, China
    Neuroreport 19:413-7. 2008
  2. doi request reprint Sox2 protects neural stem cells from apoptosis via up-regulating survivin expression
    Ruopeng Feng
    Peking University Stem Cell Research Center and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China, 100191
    Biochem J 450:459-68. 2013
  3. pmc Pax6 directly down-regulates Pcsk1n expression thereby regulating PC1/3 dependent proinsulin processing
    Ting Liu
    Peking University Stem Cell Research Center, Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
    PLoS ONE 7:e46934. 2012
  4. ncbi request reprint Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation
    Zhifeng Xiao
    Peking University Stem Cell Research Center and Cell Biology Department, Peking University Health Science Center, Beijing, China
    Cell Res 17:73-9. 2007
  5. doi request reprint Efficient induction of pluripotent stem cells from menstrual blood
    Yang Li
    Stem Cell Research Center and Department of Cell Biology, School of Basic Medical Sciences, Peking University, Beijing, China
    Stem Cells Dev 22:1147-58. 2013
  6. ncbi request reprint Cartilage-derived morphogenetic protein-1 promotes the differentiation of mesenchymal stem cells into chondrocytes
    Xiaowen Bai
    Peking University Stem Cell Research Center, Peking University Health Science Center, 38 Xue Yuan Road, Beijing 100083, China
    Biochem Biophys Res Commun 325:453-60. 2004
  7. ncbi request reprint Hepatic gene expression of NK4, an HGF-antagonist/angiogenesis inhibitor, suppresses liver metastasis and invasive growth of colon cancer in mice
    Jinhua Wen
    Division of Molecular Regenerative Medicine, Course of Advanced Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Cancer Gene Ther 11:419-30. 2004
  8. ncbi request reprint Repeated streptozotocin injections cause early onset of glomerulosclerosis in mice
    Shinya Mizuno
    Division of Molecular Regenerative Medicine, Department of Molecular Regenerative Medicine, Osaka University, Suita, Japan
    Exp Anim 53:175-80. 2004

Collaborators

  • Yang Li
  • Yanxia Zhao
  • Toshikazu Nakamura
  • Lingsong Li
  • Ruopeng Feng
  • Zhifeng Xiao
  • Na Tang
  • Ting Liu
  • Shinya Mizuno
  • Xiaowen Bai
  • Shixin Zhou
  • Zhilin Luan
  • Yinan Liu
  • Xin Dai
  • Daijun Song
  • Nicole Lu
  • Xiaolong Yang
  • Shufa Yang
  • Yaxian Kong
  • Meiyu Li
  • YuQiong Pan
  • Jiang Hu
  • Yoko Mizuno-Horikawa
  • Jens Pohl

Detail Information

Publications8

  1. doi request reprint Pax6 directly modulate Sox2 expression in the neural progenitor cells
    Jinhua Wen
    Peking University Stem Cell Research Center and Cell Biology Department, Peking University Health Science Center, Beijing, China
    Neuroreport 19:413-7. 2008
    ..Moreover, neural progenitors isolated from the Pax6(-/-) embryos showed a decreased neurosphere formation as well as proliferation...
  2. doi request reprint Sox2 protects neural stem cells from apoptosis via up-regulating survivin expression
    Ruopeng Feng
    Peking University Stem Cell Research Center and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China, 100191
    Biochem J 450:459-68. 2013
    ..In short, we have found a novel Sox2/survivin pathway that regulates NSC survival and homoeostasis, thus revealing a new mechanism of brain development, neurological degeneration and such aging-related disorders...
  3. pmc Pax6 directly down-regulates Pcsk1n expression thereby regulating PC1/3 dependent proinsulin processing
    Ting Liu
    Peking University Stem Cell Research Center, Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
    PLoS ONE 7:e46934. 2012
    ..As a protein cleaving enzyme, in addition to its expression, the activity of PC1/3 is closely related to its function. We therefore hypothesize that Pax6 mutation alters the activity of PC1/3, which affects proinsulin processing...
  4. ncbi request reprint Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation
    Zhifeng Xiao
    Peking University Stem Cell Research Center and Cell Biology Department, Peking University Health Science Center, Beijing, China
    Cell Res 17:73-9. 2007
    ..Collectively, this study may provide insight into the mechanisms by which microenvironmental niche signals regulate NSCs...
  5. doi request reprint Efficient induction of pluripotent stem cells from menstrual blood
    Yang Li
    Stem Cell Research Center and Department of Cell Biology, School of Basic Medical Sciences, Peking University, Beijing, China
    Stem Cells Dev 22:1147-58. 2013
    ..These cells were able to differentiate into various cell types of all 3 germ layers both in vitro and in vivo. Therefore, MenSCs may be a preferred candidate for generation of iPSCs...
  6. ncbi request reprint Cartilage-derived morphogenetic protein-1 promotes the differentiation of mesenchymal stem cells into chondrocytes
    Xiaowen Bai
    Peking University Stem Cell Research Center, Peking University Health Science Center, 38 Xue Yuan Road, Beijing 100083, China
    Biochem Biophys Res Commun 325:453-60. 2004
    ..This study may provide an improved induction approach using MSCs for repairing damaged cartilage...
  7. ncbi request reprint Hepatic gene expression of NK4, an HGF-antagonist/angiogenesis inhibitor, suppresses liver metastasis and invasive growth of colon cancer in mice
    Jinhua Wen
    Division of Molecular Regenerative Medicine, Course of Advanced Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Cancer Gene Ther 11:419-30. 2004
    ....
  8. ncbi request reprint Repeated streptozotocin injections cause early onset of glomerulosclerosis in mice
    Shinya Mizuno
    Division of Molecular Regenerative Medicine, Department of Molecular Regenerative Medicine, Osaka University, Suita, Japan
    Exp Anim 53:175-80. 2004
    ..Our results provide an animal tool to elucidate the molecular mechanisms of DN, for example to investigate vascular pathology in diabetic glomerular diseases...