Juan Wang

Summary

Affiliation: Peking University
Country: China

Publications

  1. pmc Specific Roles of MicroRNAs in Their Interactions with Environmental Factors
    Juan Wang
    Department of Biomedical Informatics, Peking University Health Science Center, Beijing 100191, China MOE Key Lab of Cardiovascular Sciences, Peking University, Beijing 100191, China Institute of Systems Biomedicine, Peking University, Beijing 100191, China
    J Nucleic Acids 2012:978384. 2012
  2. doi request reprint The relationship between rational drug design and drug side effects
    Juan Wang
    Department of Biomedical Informatics, MOE Key Lab of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China
    Brief Bioinform 13:377-82. 2012
  3. pmc SpliceDisease database: linking RNA splicing and disease
    Juan Wang
    Department of Biomedical Informatics, Peking University Health Science Center, MOE Key Laboratory of Molecular Cardiology, Peking University, Beijing 100191, China
    Nucleic Acids Res 40:D1055-9. 2012
  4. pmc microRNA evolution in a human transcription factor and microRNA regulatory network
    Chengxiang Qiu
    Department of Biomedical Informatics, Peking University Health Science Center, Beijing, China
    BMC Syst Biol 4:90. 2010
  5. pmc TAM: a method for enrichment and depletion analysis of a microRNA category in a list of microRNAs
    Ming Lu
    Department of Biomedical Informatics, Peking University Health Science Center, Beijing, 100191, China
    BMC Bioinformatics 11:419. 2010
  6. pmc miR2Gene: pattern discovery of single gene, multiple genes, and pathways by enrichment analysis of their microRNA regulators
    Chengxiang Qiu
    Department of Biomedical Informatics, Peking University Health Science Center, Beijing, 100191, China
    BMC Syst Biol 5:S9. 2011
  7. doi request reprint Could circulating miRNAs contribute to cancer therapy?
    Geng Chen
    Institute of Systems Biomedicine, Peking University, Beijing, 100191, China
    Trends Mol Med 19:71-3. 2013
  8. ncbi request reprint [Drug targets discovery based on dynamic signal transduction networks]
    Juan Wang
    Department of Medical Bioinformatics, School of Basic Medical Sciences, Peking University, Beijing 100191, China
    Yao Xue Xue Bao 45:1-8. 2010
  9. doi request reprint Inferring the human microRNA functional similarity and functional network based on microRNA-associated diseases
    Dong Wang
    Department of Biomedical Informatics, Peking University Health Science Center, 38 Xueyuan Road, Beijing 100191, China
    Bioinformatics 26:1644-50. 2010
  10. pmc Phylogenetic analysis of Enterovirus 71 circulating in Beijing, China from 2007 to 2009
    Junping Zhu
    Department of Pathogenic Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
    PLoS ONE 8:e56318. 2013

Detail Information

Publications13

  1. pmc Specific Roles of MicroRNAs in Their Interactions with Environmental Factors
    Juan Wang
    Department of Biomedical Informatics, Peking University Health Science Center, Beijing 100191, China MOE Key Lab of Cardiovascular Sciences, Peking University, Beijing 100191, China Institute of Systems Biomedicine, Peking University, Beijing 100191, China
    J Nucleic Acids 2012:978384. 2012
    ..In this paper, we propose an outline of the current knowledge about specific roles of miRNAs in their interactions with various EFs and analyze the literatures detailing miRNAs-EFs interactions in the context of various of diseases...
  2. doi request reprint The relationship between rational drug design and drug side effects
    Juan Wang
    Department of Biomedical Informatics, MOE Key Lab of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China
    Brief Bioinform 13:377-82. 2012
    ..These results suggest that researchers should be prudent on rationalizing the drug design. Too small distances between drug targets and diseases genes may not always be advantageous for rational design for drug discovery...
  3. pmc SpliceDisease database: linking RNA splicing and disease
    Juan Wang
    Department of Biomedical Informatics, Peking University Health Science Center, MOE Key Laboratory of Molecular Cardiology, Peking University, Beijing 100191, China
    Nucleic Acids Res 40:D1055-9. 2012
    ..For the location of the mutation, we give direct links of the entry to the respective position/region in the genome browser. The users can freely browse, search and download the data in SpliceDisease at http://cmbi.bjmu.edu.cn/sdisease...
  4. pmc microRNA evolution in a human transcription factor and microRNA regulatory network
    Chengxiang Qiu
    Department of Biomedical Informatics, Peking University Health Science Center, Beijing, China
    BMC Syst Biol 4:90. 2010
    ..According to knowledge from protein-coding genes, the investigations of gene evolution in the context of biological networks often generate valuable observations that cannot be obtained by traditional approaches...
  5. pmc TAM: a method for enrichment and depletion analysis of a microRNA category in a list of microRNAs
    Ming Lu
    Department of Biomedical Informatics, Peking University Health Science Center, Beijing, 100191, China
    BMC Bioinformatics 11:419. 2010
    ..It is interesting and important to know the common rules or patterns behind a list of miRNAs, (i.e. the deregulated miRNAs resulted from an experiment of miRNA microarray or deep-sequencing)...
  6. pmc miR2Gene: pattern discovery of single gene, multiple genes, and pathways by enrichment analysis of their microRNA regulators
    Chengxiang Qiu
    Department of Biomedical Informatics, Peking University Health Science Center, Beijing, 100191, China
    BMC Syst Biol 5:S9. 2011
    ..As various miRNA annotation data become available, exploring gene patterns by analyzing the prior knowledge of their miRNA regulators is becoming more feasible...
  7. doi request reprint Could circulating miRNAs contribute to cancer therapy?
    Geng Chen
    Institute of Systems Biomedicine, Peking University, Beijing, 100191, China
    Trends Mol Med 19:71-3. 2013
    ....
  8. ncbi request reprint [Drug targets discovery based on dynamic signal transduction networks]
    Juan Wang
    Department of Medical Bioinformatics, School of Basic Medical Sciences, Peking University, Beijing 100191, China
    Yao Xue Xue Bao 45:1-8. 2010
    ..Strategies and procedures of using network-based drug discovery will be emphasized, including multi-targets drug design and network-based drug discovery...
  9. doi request reprint Inferring the human microRNA functional similarity and functional network based on microRNA-associated diseases
    Dong Wang
    Department of Biomedical Informatics, Peking University Health Science Center, 38 Xueyuan Road, Beijing 100191, China
    Bioinformatics 26:1644-50. 2010
    ..With the rapid accumulation of miRNAs, it is increasingly needed to uncover their functional relationships in a systems level...
  10. pmc Phylogenetic analysis of Enterovirus 71 circulating in Beijing, China from 2007 to 2009
    Junping Zhu
    Department of Pathogenic Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
    PLoS ONE 8:e56318. 2013
    ..Persistent surveillance of HFMD-associated pathogens is required for predicting potential emerging viruses and related disease outbreaks...
  11. pmc Sequence fingerprints of microRNA conservation
    Bing Shi
    Department of Cardiology, Peking University Third Hospital, Beijing, China
    PLoS ONE 7:e48256. 2012
    ..In addition, the fingerprint found in this study can be predictor of miRNA conservation, and the findings are helpful in achieving a clearer understanding of miRNA function and evolution...
  12. doi request reprint The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions
    Shaogui Guo
    National Engineering Research Center for Vegetables, Beijing Academy of Agriculture and Forestry Sciences, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops North China, Beijing, China
    Nat Genet 45:51-8. 2013
    ....
  13. ncbi request reprint [Network pharmacology and drug discovery]
    Juan Wang
    Department of Biomedical Informatics, Peking University Health Science Center, Beijing 100191, China
    Sheng Li Ke Xue Jin Zhan 42:241-5. 2011
    ..This review introduced the recent progress of network pharmacology and its importance to understand the mechanism of drug actions and drug discovery...