Research Topics

Ming Ying Shang


Affiliation: Peking University
Country: China


  1. Li C, Xu F, Xie D, Jing Y, Shang M, Liu G, et al. Identification of absorbed constituents in the rabbit plasma and cerebrospinal fluid after intranasal administration of Asari Radix et Rhizoma by HS-SPME-GC-MS and HPLC-APCI-IT-TOF-MSn. Molecules. 2014;19:4857-79 pubmed publisher
    ..These findings extend our understanding of the effective substances of AR, and inspire us to make a hypothesis on the mechanism of additive effect of multiple constituents of TCMs, which is very worthy of further investigation. ..
  2. Zhang Y, Liu L, Xu F, Shang M, Liu G, Cai S. Investigation of the In Vivo Metabolism of Sibirioside A and Angoroside C in Rats by HPLC-ESI-IT-TOF-MSn. Molecules. 2018;23: pubmed publisher
    ..These findings provide a reference for studying the metabolism, distribution and pharmacological actions of phenylpropanoid glycosides in vivo. ..
  3. Su D, Yang X, Feng X, Shang M, Cai S. The diterpenes ovoideal A-G from Tirpitzia ovoidea. Molecules. 2014;19:18966-79 pubmed publisher
    ..The in vitro cytotoxic activity of compounds 1, 3-5, 8-18 was evaluated against the Hela, HepG2 and K562 cell lines. Among them, compounds 3, 9, 11, 12, 13, 14, 15, 17, 18 showed moderate inhibitory activities. ..
  4. Yang X, Xu F, Li D, Lu F, Liu G, Wang L, et al. Metabolites of Siamenoside I and Their Distributions in Rats. Molecules. 2016;21:176 pubmed publisher
    ..In addition, eight metabolites were bioactive according to literature. These findings would help to understand the metabolism and effective forms of siamenoside I and other mogrosides in vivo. ..
  5. Yang P, Xu F, Li H, Wang Y, Li F, Shang M, et al. Detection of 191 Taxifolin Metabolites and Their Distribution in Rats Using HPLC-ESI-IT-TOF-MS(n). Molecules. 2016;21: pubmed publisher
    ..These findings enhance understanding of the metabolism and effective forms of taxifolin and may provide further insight of the beneficial effects of taxifolin and its derivatives. ..
  6. Yang X, Zhang Y, Liu L, Wang Y, Shang M, Xu F, et al. Lignans and diterpenes isolated from Tirpitzia ovoidea and their biological activities. Chin J Nat Med. 2017;15:938-943 pubmed publisher
    ..2-8.3μmol·L-1. Additionally, Compounds 2, 10, 11, and 13 exhibited potent inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages at the concentration of 50μmol·L-1. ..
  7. Jing Y, Zhang Y, Shang M, Liu G, Li Y, Wang X, et al. Chemical Constituents from the Roots and Rhizomes of Asarum heterotropoides var. mandshuricum and the In Vitro Anti-Inflammatory Activity. Molecules. 2017;22: pubmed publisher
    ..9%-72.6% inhibitions at 10-5 mol/L. The results of anti-inflammatory assay suggested that lignans obtained from the CHCl₃ extract might be the main active components of Xixin. ..
  8. Jing Y, Zhang Y, Shang M, Yu J, Tang J, Liu G, et al. Phenanthrene derivatives from roots and rhizomes of Asarum heterotropoides var. mandshuricum. Fitoterapia. 2017;117:101-108 pubmed publisher
    ..Considering the other nephrotoxic phenanthrene derivatives (6, 8, 12, 15 and 16) previously tested, the results implied the potency of renal toxicity of this herb used as a medicine. ..
  9. Wang Q, Guo S, Yang X, Zhang Y, Shang M, Shang Y, et al. Flavonoids isolated from Sinopodophylli Fructus and their bioactivities against human breast cancer cells. Chin J Nat Med. 2017;15:225-233 pubmed publisher