Affiliation: Peking University
- Multipotency of human neural stem cells from fetal striatumYang Li
Department of Cell Biology, Peking University Health Science Center, Beijing, China
Neuroreport 19:1679-83. 2008..The cellular nature of the human donor cells in chimeric tissues is, however, currently unknown, and further work will be done to identify what differentiated phenotypes have developed from the human cells...
- Reprogramming of sheep fibroblasts into pluripotency under a drug-inducible expression of mouse-derived defined factorsYang Li
Stem Cell Research Center, Peking University Health Science Center, Beijing, China
PLoS ONE 6:e15947. 2011..Generation of sheep iPSCs places sheep on the front lines of large animal preclinical trials and experiments involving modification of animal genomes...
- HMDD v2.0: a database for experimentally supported human microRNA and disease associationsYang Li
Department of Cell Biology, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China, Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China and MOE Key Lab of Cardiovascular Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China
Nucleic Acids Res 42:D1070-4. 2014..Meanwhile, we also maintained the old version of HMDD. By keeping data sets up-to-date, HMDD should continue to serve as a valuable resource for investigating the roles of miRNAs in human disease. ..
- Efficient induction of pluripotent stem cells from menstrual bloodYang Li
Stem Cell Research Center and Department of Cell Biology, School of Basic Medical Sciences, Peking University, Beijing, China
Stem Cells Dev 22:1147-58. 2013..These cells were able to differentiate into various cell types of all 3 germ layers both in vitro and in vivo. Therefore, MenSCs may be a preferred candidate for generation of iPSCs...
- Genome-wide analysis of human microRNA stabilityYang Li
Department of Cell Biology, Stem Cell Research Center, Peking University School of Basic Medical Sciences, 38 Xueyuan Road, Beijing 100191, China
Biomed Res Int 2013:368975. 2013..Together, our results provided an extensive description of the global landscape, dynamics, and distinct mode of human miRNA stability, which provide help in investigating their functions in physiology and pathophysiology. ..
- Novel mutations in the CYP4V2 gene associated with Bietti crystalline corneoretinal dystrophyMinghua Shan
Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
Mol Vis 11:738-43. 2005..To further characterize the role of CYP4V2 in BCD, mutation screening has been undertaken in a cohort of affected patients with BCD from China...
- Complement factor H polymorphism in age-related maculopathy in the Chinese population: the Beijing Eye StudyYa Gao
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Capital Medical University, Beijing, China
Retina 30:443-6. 2010..The purpose of this study was to analyze the association between the Y402H polymorphism in the complement factor H and soft drusen of the macula as part of age-related maculopathy in the Chinese population...