ming li

Summary

Affiliation: dept. of endocrinology,peking union medical college hospital
Location: Beijing, China
Summary:
research focus on obesity and insulin resistance related disease;immunoassay development for biomarkers.
Publications:
1: Duan YH, Li M, Hao DS, Li DL, Wu ZH, Qiu GX. [Primary culture and adipogenic
process of pre-adipocytes from infrapatellar fat pad of osteoarthritic
patients.]. Zhonghua Yi Xue Za Zhi. 2011 Apr;91(13):902-905. Chinese. PubMed
PMID: .


2: Duan Y, Hao D, Li M, Wu Z, Li D, Yang X, Qiu G. Increased synovial fluid
visfatin is positively linked to cartilage degradation biomarkers in
osteoarthritis. Rheumatol Int. 2011 Jan 19. [Epub ahead of print] PubMed PMID:
.


3: Hao D, Li M, Wu Z, Duan Y, Li D, Qiu G. Synovial fluid level of adiponectin
correlated with levels of aggrecan degradation markers in osteoarthritis.
Rheumatol Int. 2010 May 13. [Epub ahead of print] PubMed PMID: .


4: Luo L, Zhang L, Tao M, Qiu Z, Xie J, Han Y, Li M, Li T. Adiponectin and leptin
levels in Chinese patients with HIV-related lipodystrophy: a 30-month prospective
study. AIDS Res Hum Retroviruses. 2009 Dec;25(12):1265-72. PubMed PMID: .


5: Li M, Fisette A, Zhao XY, Deng JY, Mi J, Cianflone K. Serum resistin
correlates with central obesity but weakly with insulin resistance in Chinese
children and adolescents. Int J Obes (Lond). 2009 Apr;33(4):424-39. Epub 2009 Mar
17. PubMed PMID: .


6: Li M, Yin JH, Zhang K, Wu CY. [A highly sensitive enzyme-linked immunosorbent
assay for measurement of leptin secretion in human adipocytes]. Zhonghua Yi Xue
Za Zhi. 2008 Dec 16;88(46):3293-7. Chinese. PubMed PMID: .

Publications

  1. request reprint
    Perez Matute P, Marti A, Martinez J, Moreno Aliaga M. Effects of arachidonic acid on leptin secretion and expression in primary cultured rat adipocytes. J Physiol Biochem. 2003;59:201-8 pubmed
    ..These results suggest that the inhibitory effect of the arachidonic acid on leptin secretion and expression may be due, al least in part, to the increase in the anaerobic utilization of glucose. ..
  2. request reprint
    Li M, Yin J, Zhang K, Wu C. [A highly sensitive enzyme-linked immunosorbent assay for measurement of leptin secretion in human adipocytes]. Zhonghua Yi Xue Za Zhi. 2008;88:3293-7 pubmed
    ..61, P < 0.001). A highly sensitive BA-ELISA specific for free leptin has been developed that is especially suited for the accurate measurement of the rather low leptin levels of clinical blood specimens and for basic research use. ..
  3. Li M, Fisette A, Zhao X, Deng J, Mi J, Cianflone K. Serum resistin correlates with central obesity but weakly with insulin resistance in Chinese children and adolescents. Int J Obes (Lond). 2009;33:424-39 pubmed publisher
    ..Only a small proportion of resistin variation can be explained by factors related to metabolic syndrome, suggesting that resistin is not strongly implicated in a concentration-dependent fashion in any of the examined pathologies. ..
  4. Luo L, Zhang L, Tao M, Qiu Z, Xie J, Han Y, et al. Adiponectin and leptin levels in Chinese patients with HIV-related lipodystrophy: a 30-month prospective study. AIDS Res Hum Retroviruses. 2009;25:1265-72 pubmed publisher
    ..The adiponectin level had a correlation with serum triglycerides, serum insulin concentration, and HDL-C, suggesting that adiponectin may link the metabolic abnormalities and HIV-LD. ..
  5. Hao D, Li M, Wu Z, Duan Y, Li D, Qiu G. Synovial fluid level of adiponectin correlated with levels of aggrecan degradation markers in osteoarthritis. Rheumatol Int. 2011;31:1433-7 pubmed publisher
    ..015) and AGG2 (r = 0.445, P = 0.014), but not significantly correlated with degradation marker of collagen II, CTX-II. These findings suggest that adiponectin might involve in the regulation of the degradation of cartilage matrix in OA. ..
  6. request reprint
    Duan Y, Li M, Hao D, Li D, Wu Z, Qiu G. [Primary culture and adipogenic process of pre-adipocytes from infrapatellar fat pad of osteoarthritic patients]. Zhonghua Yi Xue Za Zhi. 2011;91:902-5 pubmed
    ..Thus it may provide an ideal model for the study of endocrine function of infrapatellar fat pad and understanding its role in the pathogenesis of osteoarthritis. ..
  7. Li G, Yin J, Fu J, Li L, Grant S, Li C, et al. FGF21 deficiency is associated with childhood obesity, insulin resistance and hypoadiponectinaemia: The BCAMS Study. Diabetes Metab. 2017;43:253-260 pubmed publisher
    ..Our present findings suggest that FGF21 deficiency, rather than resistance, contribute to IR and hypoadiponectinaemia independently of obesity in young people. ..
  8. Fu J, Hou C, Li L, Feng D, Li G, Li M, et al. Vitamin D modifies the associations between circulating betatrophin and cardiometabolic risk factors among youths at risk for metabolic syndrome. Cardiovasc Diabetol. 2016;15:142 pubmed
    ..These findings may provide valuable insights in the regulation of betatrophin and help explain the observed discrepancies in literature. ..

Collaborators

Detail Information

Publications8

  1. request reprint
    Perez Matute P, Marti A, Martinez J, Moreno Aliaga M. Effects of arachidonic acid on leptin secretion and expression in primary cultured rat adipocytes. J Physiol Biochem. 2003;59:201-8 pubmed
    ..These results suggest that the inhibitory effect of the arachidonic acid on leptin secretion and expression may be due, al least in part, to the increase in the anaerobic utilization of glucose. ..
  2. request reprint
    Li M, Yin J, Zhang K, Wu C. [A highly sensitive enzyme-linked immunosorbent assay for measurement of leptin secretion in human adipocytes]. Zhonghua Yi Xue Za Zhi. 2008;88:3293-7 pubmed
    ..61, P < 0.001). A highly sensitive BA-ELISA specific for free leptin has been developed that is especially suited for the accurate measurement of the rather low leptin levels of clinical blood specimens and for basic research use. ..
  3. Li M, Fisette A, Zhao X, Deng J, Mi J, Cianflone K. Serum resistin correlates with central obesity but weakly with insulin resistance in Chinese children and adolescents. Int J Obes (Lond). 2009;33:424-39 pubmed publisher
    ..Only a small proportion of resistin variation can be explained by factors related to metabolic syndrome, suggesting that resistin is not strongly implicated in a concentration-dependent fashion in any of the examined pathologies. ..
  4. Luo L, Zhang L, Tao M, Qiu Z, Xie J, Han Y, et al. Adiponectin and leptin levels in Chinese patients with HIV-related lipodystrophy: a 30-month prospective study. AIDS Res Hum Retroviruses. 2009;25:1265-72 pubmed publisher
    ..The adiponectin level had a correlation with serum triglycerides, serum insulin concentration, and HDL-C, suggesting that adiponectin may link the metabolic abnormalities and HIV-LD. ..
  5. Hao D, Li M, Wu Z, Duan Y, Li D, Qiu G. Synovial fluid level of adiponectin correlated with levels of aggrecan degradation markers in osteoarthritis. Rheumatol Int. 2011;31:1433-7 pubmed publisher
    ..015) and AGG2 (r = 0.445, P = 0.014), but not significantly correlated with degradation marker of collagen II, CTX-II. These findings suggest that adiponectin might involve in the regulation of the degradation of cartilage matrix in OA. ..
  6. request reprint
    Duan Y, Li M, Hao D, Li D, Wu Z, Qiu G. [Primary culture and adipogenic process of pre-adipocytes from infrapatellar fat pad of osteoarthritic patients]. Zhonghua Yi Xue Za Zhi. 2011;91:902-5 pubmed
    ..Thus it may provide an ideal model for the study of endocrine function of infrapatellar fat pad and understanding its role in the pathogenesis of osteoarthritis. ..
  7. Li G, Yin J, Fu J, Li L, Grant S, Li C, et al. FGF21 deficiency is associated with childhood obesity, insulin resistance and hypoadiponectinaemia: The BCAMS Study. Diabetes Metab. 2017;43:253-260 pubmed publisher
    ..Our present findings suggest that FGF21 deficiency, rather than resistance, contribute to IR and hypoadiponectinaemia independently of obesity in young people. ..
  8. Fu J, Hou C, Li L, Feng D, Li G, Li M, et al. Vitamin D modifies the associations between circulating betatrophin and cardiometabolic risk factors among youths at risk for metabolic syndrome. Cardiovasc Diabetol. 2016;15:142 pubmed
    ..These findings may provide valuable insights in the regulation of betatrophin and help explain the observed discrepancies in literature. ..