Research Topics
Genomes and Genes | Min ChenSummaryAffiliation: Peking University Country: China Publications
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Publications
Clinical characteristics and outcomes of Chinese patients with cholesterol crystal embolism after coronary interventionLei Meng
Department of Cardiology, Peking University First Hospital, Beijing, PR China
Clin Cardiol 29:503-5. 2006..Cholesterol crystal embolism (CCE) is a complication of atherosclerosis. Vascular surgery, vascular angiography, and anticoagulation have been identified as inciting factors...
The impact factor of rheumatology journals: an analysis of 2008 and the recent 10 yearsMin Chen
Renal Division, Department of Medicine, Peking University First Hospital, 100034 Beijing, China
Rheumatol Int 31:1611-5. 2011..Over the past 10 years, rheumatology journals showed a general increase in IF and rheumatology remained a leading discipline. For journals in the English language, those from Europe had an even higher increase than those from USA...
Severe pulmonary hemorrhage in patients with end-stage renal disease in antineutrophil cytoplasmic autoantibody-associated vasculitisMin Chen
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing 100034, China
Am J Med Sci 337:411-4. 2009..However, we encountered a few patients with ESRD suffering severe pulmonary hemorrhage caused by relapse of AAV. The current study presents our observation on these patients...- Circulating neutrophil gelatinase-associated lipocalin: a useful biomarker for assessing disease activity of ANCA-associated vasculitisMin Chen
Department of Medicine, Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China
Rheumatology (Oxford) 48:355-8. 2009..The purpose of the current study is to investigate whether NGAL is a useful biomarker for assessing disease activity of patients with AAV... - Follow-up of avidity and titre of anti-myeloperoxidase antibodies in sera from patients with propylthiouracil-induced vasculitisYing Gao
Department of Nephrology, Peking University First Hospital, Beijing, China
Clin Endocrinol (Oxf) 66:543-7. 2007..The current study aimed to follow-up the avidity and titre of anti-MPO antibodies in sequential sera from patients with PTU-induced ANCA-associated systemic vasculitis (AASV)... - Clinical and pathological features of renal involvement in propylthiouracil-associated ANCA-positive vasculitisFeng Yu
Department of Nephrology, Peking University First Hospital, Beijing, PR China
Am J Kidney Dis 49:607-14. 2007..We present a series of Chinese patients with renal involvement in PTU-associated ANCA-positive vasculitis and describe their clinical and pathological characteristics... - Clinical and pathological characteristics and outcomes of Chinese patients with primary anti-neutrophil cytoplasmic antibodies-associated systemic vasculitis with immune complex deposition in kidneyFeng Yu
Department of Nephrology, Peking University First Hospital, Beijing, China
Nephrology (Carlton) 12:74-80. 2007..To analyse the clinical and pathological characteristics of Chinese patients with immune complex deposition in kidney in anti-neutrophil cytoplasmic antibodies (ANCA)-positive vasculitis... - Antineutrophil cytoplasmic autoantibody-negative Pauci-immune crescentic glomerulonephritisMin Chen
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing 100034, P R China
J Am Soc Nephrol 18:599-605. 2007..The renal survival was poorer in ANCA-negative patients than that in ANCA-positive ones (P < 0.05). ANCA-negative pauci-immune CrGN was not rare and might represent an independent disease entity from ANCA-positive vasculitis... - Association of HLA genes with clinical outcomes of ANCA-associated vasculitisDong Yuan Chang
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, and Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China
Clin J Am Soc Nephrol 7:1293-9. 2012..The HLA system plays a central role in the distinction between self antigens and non-self antigens. This study aimed to investigate the association between HLA genes and the outcomes of patients with ANCA-associated vasculitis (AAV)... - Renal histology in Chinese patients with anti-myeloperoxidase autoantibody-positive Wegener's granulomatosisMin Chen
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing 100034, PR China
Nephrol Dial Transplant 22:139-45. 2007..However, our previous study suggested that patients with MPO-ANCA positive WG were common in Chinese. This study aimed to analyse the renal histology of patients with MPO-ANCA positive WG... - Cross-reaction of anti-DNA autoantibodies with membrane proteins of human glomerular mesangial cells in sera from patients with lupus nephritisHui Du
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing 100034, PR China
Clin Exp Immunol 145:21-7. 2006..In conclusion, anti-DNA autoantibodies could cross-react directly with cell membrane proteins of human glomerular mesangial cells and might play an important role in the pathogenetic mechanism in lupus nephritis... - Urinary kidney injury molecule-1 in patients with IgA nephropathy is closely associated with disease severityPeng Cheng Xu
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China
Nephrol Dial Transplant 26:3229-36. 2011..Urinary kidney injury molecule-1 (KIM-1) is a sensitive biomarker for proximal tubule injury. The aim of the study is to investigate the value of KIM-1 as a biomarker for assessing the renal injury in IgAN... - Antineutrophil cytoplasmic autoantibody-associated vasculitis in older patientsMin Chen
Department of Medicine, Peking University First Hospital, Beijing, China
Medicine (Baltimore) 87:203-9. 2008..Age and pulmonary infection were independent predictors of death... - Antineutrophil cytoplasmic autoantibodies in patients with systemic lupus erythematosus recognize a novel 69 kDa target antigen of neutrophil granulesMin Chen
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing, China
Nephrology (Carlton) 10:491-5. 2005..The anti-69 kDa autoantibodies might be associated with photosensitivity and oral ulcer in patients with SLE... - C-reactive protein enhances the respiratory burst of neutrophils-induced by antineutrophil cytoplasmic antibodyPeng Cheng Xu
Renal Division, Department of Medicine, Peking University First Hospital, Beijing 100034, China
Mol Immunol 52:148-54. 2012..So CRP can prime neutrophils and enhance the respiratory burst induced by ANCA and might be pathogenic in AAV... - Propylthiouracil-induced antineutrophil cytoplasmic antibody-associated vasculitisMin Chen
Renal Division, Department of Medicine, Peking University First Hospital, Xicheng District, Beijing 100034, China
Nat Rev Nephrol 8:476-83. 2012..The duration of immunosuppressive therapy might be shorter than in primary AAV, depending on the severity of organ damage, and maintenance therapy is not always necessary... - Influence of myeloperoxidase-catalyzing reaction on the binding between myeloperoxidase and anti-myeloperoxidase antibodiesPeng Cheng Xu
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China
Hum Immunol 73:364-9. 2012..91 ± 0.84 vs 3.57 ± 0.84, p < 0.001, expressed as the lgT). These data demonstrated that MPO-catalyzing reaction could potentially increase the antigenicity of MPO... - Influence of variable domain glycosylation on anti-neutrophil cytoplasmic autoantibodies and anti-glomerular basement membrane autoantibodiesPeng Cheng Xu
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing 100034, China
BMC Immunol 13:10. 2012.... - Characteristics and outcome of Chinese patients with both antineutrophil cytoplasmic antibody and antiglomerular basement membrane antibodiesJuan Zhao
Renal Division, Department of Medicine, Peking University First Hospital, Beijing, PR China
Nephron Clin Pract 107:c56-62. 2007.... - Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitisGuang qun Xing
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing 100034, China
J Clin Immunol 29:282-91. 2009..This study was to investigate the evidence for complement activation in renal biopsy specimens of patients with myeloperoxidase (MPO)-antineutrophil cytoplasmic autoantibody (ANCA)-associated pauci-immune vasculitis... - Higher DEFB4 genomic copy number in SLE and ANCA-associated small vasculitisXu Jie Zhou
Renal Division, Peking University First Hospital, Peking University Institute of Nephrology, No 8 Xi Shi Ku Street, Xi Cheng District, Beijing 100034, China
Rheumatology (Oxford) 51:992-5. 2012..This study aims to investigate whether the DEFB4 genomic copy number variations associate with the susceptibility to these two autoimmune diseases... - Differential deposition of C4d and MBL in glomeruli of patients with ANCA-negative pauci-immune crescentic glomerulonephritisGuang qun Xing
Renal Division, Department of Medicine, Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, Peking University First Hospital, Peking University, Beijing, China
J Clin Immunol 30:144-56. 2010..This study was to investigate the evidence of complement activation in renal biopsy specimens of patients with ANCA-negative pauci-immune CrGN... - Autoantibodies against glomerular mesangial cells and their target antigens in lupus nephritisMin Chen
Renal Division, Institute of Nephrology, Peking University First Hospital, Beijing, P.R. China
Ren Fail 27:507-13. 2005..CONCLUSIONS: There are autoantibodies directly against heterogeneous antigens of human glomerular mesangial cells in sera from patients with lupus nephritis, and some of them might be associated with different clinical manifestations... - IgG subclass distribution, affinity of anti-myeloperoxidase antibodies in sera from patients with Wegener's granulomatosis and microscopic polyangiitisLi Jun Liu
Renal Division, Department of Medicine Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China
Nephrology (Carlton) 13:629-35. 2008..The aim of this study was to compare the immunological characteristics of MPO-ANCA in patients with WG and MPA... - Immunofixation electrophoresis was highly specific for the diagnosis of renal light-chain amyloidosisFu de Zhou
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, and Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China
Am J Med Sci 345:18-21. 2013..This study aimed to evaluate the sensitivity and specificity of serum and urine using immunofixation electrophoresis (IFE) in the diagnosis of renal AL amyloidosis in patients older than 40 years... - High potential to reverse the inhibition of myeloperoxidase by ceruloplasmin of anti-myeloperoxidase autoantibodies of IgG3 subclassPeng Cheng Xu
Renal Division, Department of Medicine, Peking University First Hospital, China
Autoimmunity 45:218-25. 2012..217). In conclusion, MPO-ANCA of IgG3 subclass might have stronger ability to reverse the inhibition of MPO by CP than other subclasses... - p38MAPK, ERK and PI3K signaling pathways are involved in C5a-primed neutrophils for ANCA-mediated activationJian Hao
Renal Division, Key Laboratory of Renal Disease, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Ministry of Health of China, Beijing, China
PLoS ONE 7:e38317. 2012..The current study further investigated the signaling pathways of C5a-mediated priming of human neutrophils for ANCA-induced neutrophil activation... - Comparison of characteristics of natural autoantibodies against myeloperoxidase and anti-myeloperoxidase autoantibodies from patients with microscopic polyangiitisPeng Cheng Xu
Department of Medicine, Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China
Rheumatology (Oxford) 50:1236-43. 2011..Natural autoantibodies (NAAs) against MPO exist in normal human plasma. In the current study, the immune characteristics of MPO-NAA and MPO-ANCA were examined and compared with the aim to investigate the pathogenesis of MPO-ANCA... - The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patientsHuan Luo
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Beijing 100034, China
BMC Nephrol 12:21. 2011..The present study further analyzed the association between anti-GBM disease and HLA-DQB1, -DQA1, and -DPB1 genes. Apart from this, we tried to locate the potential risk amino acid residues of anti-GBM disease... - Anti-endothelial cell antibodies in antineutrophil cytoplasmic antibodies negative pauci-immune crescentic glomerulonephritisMin Cong
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China
Nephrology (Carlton) 13:228-34. 2008..The purpose of this study is to investigate the prevalence of AECA and their possible clinical significance in ANCA-negative pauci-immune CrGN... - The target antigens of antineutrophil cytoplasmic antibodies (ANCA) induced by propylthiouracilYing Gao
Department of Nephrology, Peking University First Hospital, Beijing 100034, PR China
Int Immunopharmacol 7:55-60. 2007..The aim of the current study was to detect ANCA specificities in sera from patients with PTU-induced ANCA with and without clinical vasculitis... - Involvement of protein kinase C in C5a-primed neutrophils for ANCA-mediated activationJian Hao
Renal Division, Department of Medicine, Peking University, First Hospital, Peking University Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of Chronic Kidney Disease Prevention and Treatment Peking University, Ministry of Education, Peking Tsinghua Center for Life Sciences, Beijing 100034, China Renal Division, Department of Medicine, The Affiliated Hospital of Inner Mongolia Medical University, Huhehot, Inner Mongolia 010050, China
Mol Immunol 54:68-73. 2013..5 in untreated cells to 1071.3±81.3 after C5a treatment and decreased to 827.3±48.1 by BIS (P<0.05). Activation of PKC is an important step in the translocation of ANCA antigens and C5a-induced activation of neutrophils by ANCA... - The renal histopathological spectrum of patients with nephrotic syndrome: an analysis of 1523 patients in a single Chinese centreFu de Zhou
Department of Medicine, Peking University First Hospital, People s Republic of China
Nephrol Dial Transplant 26:3993-7. 2011..Nephrotic syndrome is caused by a variety of glomerulopathy. The current study investigated the renal histopathological spectrum of patients with nephrotic syndrome who received a renal biopsy in our department within the last 15 years... - Neutrophil degranulation in antineutrophil cytoplasmic antibody-negative pauci-immune crescentic glomerulonephritisFang Wang
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Beijing, China
J Nephrol 22:491-6. 2009..This study aims to investigate the evidence for neutrophil activation and degranulation at disease presentation in patients with renal biopsy-proven ANCA-negative pauci-immune CrGN... - ANCA-negative pauci-immune crescentic glomerulonephritisMin Chen
Renal Division, Department of Medicine, Peking University First Hospital, Beijing 100034, China
Nat Rev Nephrol 5:313-8. 2009..We also discuss the possible pathogenesis of ANCA-negative pauci-immune crescentic glomerulonephritis, paying particular attention to the mechanisms and role of neutrophil activation... - Complement deposition in renal histopathology of patients with ANCA-associated pauci-immune glomerulonephritisMin Chen
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing 100034, China
Nephrol Dial Transplant 24:1247-52. 2009..The current study investigated the clinical and pathological significance of complement deposition in renal histopathology of patients with ANCA-associated pauci-immune glomerulonephritis... - Autoantibodies against monomeric C-reactive protein in sera from patients with lupus nephritis are associated with disease activity and renal tubulointerstitial lesionsYing Tan
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, and Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China
Hum Immunol 69:840-4. 2008..276), interstitial fibrosis (r = 0.211), and chronicity index score (r = 0.243). Autoantibodies against mCRP are prevalent in patients with lupus nephritis and are associated with disease activity and renal tubulointerstitial lesions... - Follow-up of avidity and titer of anti-myeloperoxidase antibodies in sera from patients with primary ANCA-associated vasculitisWei Lin
Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Ministry of Health of China, Beijing, People s Republic of China
Autoimmunity 42:198-202. 2009..Avidity and titer of MPO-ANCA did not decreased significantly during remission in AAV, indicating the chronic repeated antigen stimulation was not removed, which might be the reason for recurrent relapses... - Renal neutrophils infiltration in antineutrophil cytoplasmic antibodies-negative pauci-immune crescentic glomerulonephritisGuang qun Xing
Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China
Am J Med Sci 340:474-80. 2010.... - The immunopathological spectrum of crescentic glomerulonephritis: a survey of 106 patients in a single Chinese centerWei Lin
Renal Division, Department of Medicine, Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, Peking University First Hospital, Peking University, Beijing, China
Nephron Clin Pract 116:c65-74. 2010..Crescentic glomerulonephritis (CrGN) is a severe form of glomerular injury. We retrospectively analyzed data from Chinese patients with CrGN in our center to characterize the immunopathological spectrum of CrGN... - Non-DNA-binding antibodies in patients with lupus nephritis could recognize membrane proteins of glomerular mesangial cellsHui Du
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing, 100034, People's Republic of China
J Clin Immunol 26:138-44. 2006..Although the target antigens might not be cell specific, the roles of these autoantibodies in the pathogenesis of lupus nephritis need further investigation... - Normoalbuminaemia is associated with IgA nephropathy in primary glomerulopathy with nephrotic-range proteinuria in Chinese patientsMin Chen
Renal Division, Department of Medicine, Peking University First Hospital, Beijing 100034, China
Nephrol Dial Transplant 26:1247-52. 2011..However, patients may have normal levels of serum albumin despite heavy proteinuria in many circumstances. This study analysed factors affecting serum levels of albumin in primary glomerulopathy patients with nephrotic-range proteinuria... - Relapses in patients with antineutrophil cytoplasmic autoantibody-associated vasculitis: likely to begin with the same organ as initial onsetMin Chen
Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China
J Rheumatol 35:448-50. 2008..In antineutrophil cytoplasmic antibody-associated vasculitis (AAV), relapses constitute a challenge despite initial good control. Our objective was to investigate whether patients with relapses shared the same initial organ involvement... - Inhibition of oxidation activity of myeloperoxidase (MPO) by propylthiouracil (PTU) and anti-MPO antibodies from patients with PTU-induced vasculitisAi Hua Zhang
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing 100034, PR China
Clin Immunol 122:187-93. 2007..In conclusions, the oxidation activity of MPO could be inhibited by PTU and PTU-induced MPO-ANCA in a dose-dependent manner, which might be involved in the pathogenesis PTU-induced vasculitis... - Re-evaluation of the histopathologic classification of ANCA-associated glomerulonephritis: a study of 121 patients in a single centerDong Yuan Chang
Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China
Nephrol Dial Transplant 27:2343-9. 2012..This study aims to re-evaluate the new classification for its prognostic capacity in an independent Chinese series... - Characteristics of Chinese patients with Wegener's granulomatosis with anti-myeloperoxidase autoantibodiesMin Chen
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing, People s Republic of China
Kidney Int 68:2225-9. 2005..However, Chinese patients with MPO-ANCA positive WG were frequently diagnosed. We now analyze the characteristics of patients with MPO-ANCA positive WG and investigate the difference between patients with MPO-ANCA and PR3-ANCA... - [An analysis of multi-system involvement and renal pathology of anti-neutrophil cytoplasmic autoantibodies-related vasculitis]Min Chen
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing 100034, China
Zhonghua Nei Ke Za Zhi 44:828-31. 2005..5%. CONCLUSIONS: AASV is a common autoimmune disease in Chinese. For patients with multi-system damage, an ANCA test should be performed in order to make an early diagnosis and start therapy in time... - [Inhibition of oxidative activity of myeloperoxidase by anti-myeloperoxidase antibodies from patients with microscopic polyangiitis]Jie Chen
Renal Division, Peking University First Hospital, Beijing 100034, China
Beijing Da Xue Xue Bao 40:155-9. 2008.... - [Anti-mesangial cell autoantibodies and their target antigens in lupus nephritis]Min Chen
Renal Division, The First Hospital and Institute of Nephrology, Peking University, Beijing 100034, China
Zhonghua Nei Ke Za Zhi 42:851-3. 2003..Anti-MC autoantibodies may have a pathogenic role in lupus nephritis and some anti-MC autoantibodies may be associated with different clinical manifestations... - Clinical and pathological features of renal amyloidosis: an analysis of 32 patients in a single Chinese centreZhen Qu
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China
Nephrology (Carlton) 15:102-7. 2010..To summarize the clinical and pathological features of renal amyloidosis in order to achieve early diagnosis... - Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody-associated vasculitisShen Ju Gou
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of CKD Prevention and Treatment, Ministry of Education of China, Beijing, China
Kidney Int 83:129-37. 2013..Thus, systemic activation of complement by the alternative pathway takes place in human AAV. Circulating Bb might be a useful biomarker in assessing disease activity of AAV... - Influence of myeloperoxidase by anti-myeloperoxidase antibodies and its association with the disease activity in microscopic polyangiitisPeng Cheng Xu
Department of Medicine, Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Beijing, China
Rheumatology (Oxford) 49:2068-75. 2010..This study investigated potential associations between the influence of MPO-ANCA on the oxidation activity of MPO and the clinical manifestations as well as immunological characteristics of MPO-ANCA... - The association of HLA-DRB1 alleles with antineutrophil cytoplasmic antibody-associated systemic vasculitis in Chinese patientsHuan Luo
Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China
Hum Immunol 72:422-5. 2011..HLA-DRB1*1202 was prevalent among patients with PR3-ANCA-positive WG... - Characterization of anti-mesangial cell antibodies and their target antigens in patients with lupus nephritisHui Du
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing, 100034, PR China
J Clin Immunol 25:281-7. 2005..Anti-mesangial cell antibodies might play some role in the pathogenesis of lupus nephritis(LN)... - ANCA-associated vasculitides--advances in pathogenesis and treatmentMin Chen
Renal Division, Peking University First Hospital, Beijing 100034, China
Nat Rev Rheumatol 6:653-64. 2010..Controlled trials in which specific immune effector cells and molecules are being therapeutically targeted have been initiated or are currently being planned... - [The clinical features and outcomes of immunoglobulin light-chain amyloidosis with heart involvement]Lei Meng
Department of Cardiology, Peking University First Hospital, Beijing 100034, China
Zhonghua Xin Xue Guan Bing Za Zhi 35:340-3. 2007..To analyze the clinical features and outcomes of patients with immunoglobulin light-chain amyloidosis (AL) who had heart involvement... - Epitope Analysis of Anti-Myeloperoxidase Antibodies in Patients with ANCA-Associated VasculitisShen Ju Gou
Renal Division, Department of Medicine, Peking University First Hospital, Peking University Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of Chronic Kidney Disease Prevention and Treatment Peking University, Ministry of Education, Beijing, China
PLoS ONE 8:e60530. 2013..The current study aimed to analyze the association between the linear epitopes of MPO-ANCA and clinicopathological features of patients with AAV... - C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitisJun Yuan
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing 100034, China
Arthritis Res Ther 14:R140. 2012..In particular, C5a plays a central role. In this study, plasma and urinary levels of C5a as well as renal C5a receptors (CD88 and C5L2) expression were investigated in patients with AAV... - [Serological antibodies comparison of a hepatitis E outbreak]Chun rong Tan
Department of Clinical Laboratory, Beijing Shi Ji Tan Hospital, Beijing, China
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 19:35-8. 2005..To compare the serological characters of an outbreak of hepatitis E and evaluate sensitivity and specificity of anti-HEV E2-IgM... - Plasma catecholamine release-inhibitory peptide catestatin in patients with essential hypertensionLei Meng
Department of Cardiology, Peking University First Hospital, Beijing, People s Republic of China
J Cardiovasc Med (Hagerstown) 12:643-7. 2011..Catestatin plays an important role in the adjustment of blood pressure and cardiac function. We investigated levels of plasma catestatin in essential hypertension and the relationship between catestatin and left ventricular hypertrophy... - Three-dimensional turbo-spin-echo amide proton transfer MR imaging at 3-Tesla and its application to high-grade human brain tumorsXuna Zhao
Philips Healthcare, Beijing, China
Mol Imaging Biol 15:114-22. 2013..In this study, we demonstrate the feasibility of applying a turbo-spin-echo (TSE)-based, three-dimensional (3D) APT sequence into routine clinical practice for patients with brain tumors... - Invasive pulmonary aspergillosis in patients with antineutrophil cytoplasmic antibody associated vasculitisTao Su
Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China
J Clin Rheumatol 15:380-2. 2009..We retrospectively analyze the clinical characteristics of our patients with IPA in AAV... - Effects of acupuncture therapy on abdominal fat and hepatic fat content in obese children: a magnetic resonance imaging and proton magnetic resonance spectroscopy studyHong Zhang
Department of Radiology, Beijing Hospital, No 1 Dahua Road, Dongcheng, Beijing, China
J Altern Complement Med 17:413-20. 2011..The aim of this study was to use magnetic resonance imaging (MRI) together with proton magnetic resonance spectroscopy ((1)H-MRS) to study the influence of acupuncture therapy on abdominal fat and hepatic fat content in obese children... - Measles outbreak on a college campus transmitted through internet cafésYan Jin
Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention, Beijing, China
J Infect Dis 204:S471-5. 2011..During March 2008, a college in Urumqi, capital of Xinjiang Uygur Autonomous Region in China, reported a measles outbreak, amid a city-wide outbreak involving >2700 cases... - Tacrolimus combined with corticosteroids in treatment of nephrotic idiopathic membranous nephropathy: a multicenter randomized controlled trialMin Chen
Department of Nephrology, Peking University First Hospital, Beijing, China
Am J Med Sci 339:233-8. 2010..However, the effectiveness of tacrolimus versus classic regimen and its potential nephrotoxicity remain inconclusive. This study evaluated the efficacy and safety of tacrolimus plus prednisone in patients with nephrotic IMN... - Improving the management of anemia in hemodialysis patients by implementing the continuous quality improvement programMin Chen
Renal Division and Institute of Nephrology, Peking University First Hospital, Beijing, China
Blood Purif 24:282-6. 2006..4 +/- 14.23 g/l (p < 0.0001). The proportion of patients with an adequate iron status increased from 28.0 to 53.3% (p < 0.05). CONCLUSION: The CQI program is a useful method in the management of anemia in hemodialysis patients... - [Cardiovascular events in patients with chronic kidney disease]Lei Meng
Department of Cardiology, Peking University First Hospital, Beijing 100034, China
Zhonghua Xin Xue Guan Bing Za Zhi 37:53-5. 2009..Cardiovascular event is common and is an important cause of death for patients with chronic kidney disease (CKD). The purpose of current study is to analyze the related risk factors of cardiovascular event in patients with CKD... - [Antigens of antineutrophil cytoplasmic autoantibodies in recognizing a novel neutrophil granule antigen in lupus nephritis and its association with photosensitivity and oral ulceration]Min Chen
Renal Division, The First Hospital and Institute of Nephrology, Peking University, Beijing 100034, China
Zhonghua Nei Ke Za Zhi 41:766-8. 2002..CONCLUSIONS: A novel 69,000 protein in human neutrophil granules is identified as a target antigen of ANCA in LN patients. The anti-69,000 autoantibodies may be associated with photosensitivity and oral ulcer in LN patients... - Use acupuncture to treat functional constipation: study protocol for a randomized controlled trialYing Li
Chengdu University of Traditional Chinese Medicine, and First Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China
Trials 13:104. 2012..Whether acupuncture is effective for patients with functional constipation is still unclear. Therefore, we report the protocol of a randomized controlled trial of using acupuncture to treat functional constipation... - Gamma-secretase gene mutations in familial acne inversaBaoxi Wang
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences Peking Union Medical College CAMS PUMC, Beijing, China
Science 330:1065. 2010.... - Experimental evaluation of dual acceptance window weighting function for right coronary MR angiography at 3.0TXuna Zhao
Institute of Heavy Ion Physics, Beijing Key Laboratory of Medical Physics and Engineering, Physics School, Peking University, Beijing 100871, China
Magn Reson Imaging 28:797-801. 2010.... - Brain natriuretic peptide rs198388 polymorphism and essential hypertension in Hunan Han peopleMin Chen
Department of Cardiology, Xiangya Hospital, Central South University, Changsha 410008, China
Zhong Nan Da Xue Xue Bao Yi Xue Ban 35:1207-13. 2010..To investigate the relation between brain natriuretic peptide (BNP) rs198388 polymorphism and the susceptibility of essential hypertension in Han population of Hunan... - [The effect of different loading doses of clopidogrel on platelet aggregation]Qian zhu Liu
Department of Cardiology, Peking University First Hospital, Beijing 100034, China
Zhonghua Nei Ke Za Zhi 46:107-10. 2007..To compare the short-term efficacy and safety of high loading dose (600 mg) clopidogrel treatment with those of routine loading dose (300 mg) in patients with acute coronary syndrome and provide evidence for planning clopidogrel treatment... - [Sero-epidemiological characteristics of antibody to SARS-associated coronavirus in Gansu Province]De-shan Yu
Department of Acute Infectious Disease Control and Prevention, Gansu Centers for Disease Control and Prevention, Lanzhou 730000, China
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 18:325-7. 2004..The low positive rate of the persons who closely contacted SARS patients and normal subjects suggests that SARS probably had no subclinical infection...