Ai Rong Qian

Summary

Affiliation: Northwestern Polytechnical University
Country: China

Publications

  1. ncbi request reprint Role of microRNAs in osteoblasts differentiation and bone disorders
    Yasir Arfat
    Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, 127 Youyi Xilu, Xi an, 710072, P R China
    Curr Med Chem 22:748-58. 2015
  2. doi request reprint Fractal dimension as a measure of altered actin cytoskeleton in MC3T3-E1 cells under simulated microgravity using 3-D/2-D clinostats
    A R Qian
    Key Laboratory for Space Biosciences and Biotechnology, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    IEEE Trans Biomed Eng 59:1374-80. 2012
  3. pmc Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells
    Ai Rong Qian
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, PR China
    J Exp Clin Cancer Res 27:50. 2008
  4. doi request reprint Diamagnetic levitation causes changes in the morphology, cytoskeleton, and focal adhesion proteins expression in osteocytes
    A R Qian
    Key Laboratory for Space Biosciences and Biotechnology, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    IEEE Trans Biomed Eng 59:68-77. 2012
  5. pmc Large gradient high magnetic fields affect osteoblast ultrastructure and function by disrupting collagen I or fibronectin/αβ1 integrin
    Ai Rong Qian
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University Xi an, Xi an, China
    PLoS ONE 8:e51036. 2013
  6. doi request reprint Large gradient high magnetic field affects the association of MACF1 with actin and microtubule cytoskeleton
    Ai Rong Qian
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an, Shaan Xi Province, PR China
    Bioelectromagnetics 30:545-55. 2009
  7. doi request reprint Physiological effects of microgravity on bone cells
    Yasir Arfat
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, 127 Youyi Xilu, Xi an, 710072, People s Republic of China
    Calcif Tissue Int 94:569-79. 2014
  8. pmc GeneChip expression profiling reveals the alterations of energy metabolism related genes in osteocytes under large gradient high magnetic fields
    Yang Wang
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    PLoS ONE 10:e0116359. 2015
  9. doi request reprint Human mesenchymal stem cells are sensitive to abnormal gravity and exhibit classic apoptotic features
    Rui Meng
    Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an, China
    Acta Biochim Biophys Sin (Shanghai) 43:133-42. 2011
  10. ncbi request reprint siRNA targeted against HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression in hepatocellular carcinoma cell line via ERK1/2 pathway
    Hui Yun Xu
    Cell Engineering Research Centre and Department of Cell Biology, State Key Laboratory of Cancer Biology, Fourth Military Medical University, 17 West Changle Street, Xi an, Shaanxi Province 710032, PR China
    Cancer Lett 247:336-44. 2007

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Role of microRNAs in osteoblasts differentiation and bone disorders
    Yasir Arfat
    Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, 127 Youyi Xilu, Xi an, 710072, P R China
    Curr Med Chem 22:748-58. 2015
    ..This recap highlights the role of miRNAs in osteoblasts differentiation and emphasizes their potential therapeutic role in metabolic bone disorders. ..
  2. doi request reprint Fractal dimension as a measure of altered actin cytoskeleton in MC3T3-E1 cells under simulated microgravity using 3-D/2-D clinostats
    A R Qian
    Key Laboratory for Space Biosciences and Biotechnology, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    IEEE Trans Biomed Eng 59:1374-80. 2012
    ....
  3. pmc Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells
    Ai Rong Qian
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, PR China
    J Exp Clin Cancer Res 27:50. 2008
    ..MMPs degrade the ECM to promote tumor metastasis. The aim of this study is to investigate the effects of small interfering RNA (siRNA) against CD147 (si-CD147) on hepatocellular carcinoma cells' (SMMC-7721) architecture and functions...
  4. doi request reprint Diamagnetic levitation causes changes in the morphology, cytoskeleton, and focal adhesion proteins expression in osteocytes
    A R Qian
    Key Laboratory for Space Biosciences and Biotechnology, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    IEEE Trans Biomed Eng 59:68-77. 2012
    ..The diamagnetic levitation may be a novel ground-based space-gravity simulator and can be used for biological experiment at cellular level...
  5. pmc Large gradient high magnetic fields affect osteoblast ultrastructure and function by disrupting collagen I or fibronectin/αβ1 integrin
    Ai Rong Qian
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University Xi an, Xi an, China
    PLoS ONE 8:e51036. 2013
    ..In conclusion, LG-HMF affects osteoblast ultrastructure, cell viability, and ALP secretion, and the changes caused by LG-HMF may be related to disrupting col I or FN/αβ1 integrin...
  6. doi request reprint Large gradient high magnetic field affects the association of MACF1 with actin and microtubule cytoskeleton
    Ai Rong Qian
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an, Shaan Xi Province, PR China
    Bioelectromagnetics 30:545-55. 2009
    ..In conclusion, LG-HMF affects osteoblast-like cell viability, MACF1 distribution, expression, and its association with cytoskeleton to some extent...
  7. doi request reprint Physiological effects of microgravity on bone cells
    Yasir Arfat
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, 127 Youyi Xilu, Xi an, 710072, People s Republic of China
    Calcif Tissue Int 94:569-79. 2014
    ..The objective of this review is to summarize the recent research on bone cells under microgravity conditions based on advances in the field. ..
  8. pmc GeneChip expression profiling reveals the alterations of energy metabolism related genes in osteocytes under large gradient high magnetic fields
    Yang Wang
    Key Laboratory for Space Biosciences and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    PLoS ONE 10:e0116359. 2015
    ..The identification of sensitive genes to special environments may provide some potential targets for preventing and treating bone loss or osteoporosis. ..
  9. doi request reprint Human mesenchymal stem cells are sensitive to abnormal gravity and exhibit classic apoptotic features
    Rui Meng
    Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, Faculty of Life Sciences, Northwestern Polytechnical University, Xi an, China
    Acta Biochim Biophys Sin (Shanghai) 43:133-42. 2011
    ..These results implied that hMSCs were sensitive to abnormal gravity and exhibited classic apoptotic features, which might be associated with p53 signaling...
  10. ncbi request reprint siRNA targeted against HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression in hepatocellular carcinoma cell line via ERK1/2 pathway
    Hui Yun Xu
    Cell Engineering Research Centre and Department of Cell Biology, State Key Laboratory of Cancer Biology, Fourth Military Medical University, 17 West Changle Street, Xi an, Shaanxi Province 710032, PR China
    Cancer Lett 247:336-44. 2007
    ..MEK1/2 inhibitor, U0126, inhibited MMP-2, FAK and actin expression in FHCC-98 cell line. The findings indicate that si-HAb18G inhibits gelatinase production, actin and FAK expression in FHCC-98 via an ERK1/2 signaling pathway...
  11. ncbi request reprint Targeting radioimmunotherapy of hepatocellular carcinoma with iodine (131I) metuximab injection: clinical phase I/II trials
    Zhi Nan Chen
    Cell Engineering Research Centre and Department of Cell Biology, State Key Laboratory of Cancer Biology, Fourth Military Medical University, Xi an, China
    Int J Radiat Oncol Biol Phys 65:435-44. 2006
    ..We developed iodine (131I) metuximab injection (Licartin), a novel 131I-labeled HAb18G/CD147-specific monoclonal antibody Fab'2 fragment, and evaluated its safety, pharmacokinetics, and clinical efficacy on HCC in Phase I/II trials...
  12. doi request reprint Mineralization initiation of MC3T3-E1 preosteoblast is suppressed under simulated microgravity condition
    Li Fang Hu
    Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Xi an, 710072, China
    Cell Biol Int 39:364-72. 2015
    ..ERK signaling might be involved in this process. These results are relevant to the decrease of osteoblast maturation and bone formation under microgravity condition. ..
  13. pmc A hypomagnetic field aggravates bone loss induced by hindlimb unloading in rat femurs
    Bin Jia
    Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Xi an, China
    PLoS ONE 9:e105604. 2014
    ..Excessive levels of reactive oxygen species would stimulate osteoblasts to secrete receptor activator of nuclear factor-κB ligand and promote the maturation and activation of osteoclasts and thus eventually cause bone resorption...