Affiliation: Northwest A and F University
- Zhao X, Xiang H, Bai X, Fei N, Huang Y, Song X, et al. Porcine parvovirus infection activates mitochondria-mediated apoptotic signaling pathway by inducing ROS accumulation. Virol J. 2016;13:26 pubmed publisher..All these results suggest that PPV-induced ROS accumulation mediates apoptosis in ST cells, which provided theoretical basis for the molecular pathogenesis of PPV infection. ..
- Xu D, Du Q, Han C, Wang Z, Zhang X, Wang T, et al. p53 signaling modulation of cell cycle arrest and viral replication in porcine circovirus type 2 infection cells. Vet Res. 2016;47:120 pubmed..Taken together, this study demonstrates that PCV2 infection induces S phase accumulation to favor viral replication in host cells through activation of the p53 pathway. ..
- Zhang W, Wang Z, Zhang L, Zhang Z, Chen J, Chen W, et al. Melatonin stimulates the secretion of progesterone along with the expression of cholesterol side-chain cleavage enzyme (P450scc) and steroidogenic acute regulatory protein (StAR) in corpus luteum of pregnant sows. Theriogenology. 2018;108:297-305 pubmed publisher..The data support the presence of MT1 and MT2 in porcine CL and a regulatory role for melatonin in luteal function through MT1 and MT2-mediated signal transduction pathways. ..
- Zhang L, Huang Y, Wang Z, Luo X, Zhang H, Du Q, et al. Establishment and characterization of a telomerase immortalized porcine luteal cells. Theriogenology. 2017;94:105-113 pubmed publisher..In summary, we developed an immortalized porcine luteal cell line which maintained its originally morphological, biological and functional characteristics. ..
- Zhao X, Bai X, Guan L, Li J, Song X, Ma X, et al. microRNA-4331 Promotes Transmissible Gastroenteritis Virus (TGEV)-induced Mitochondrial Damage Via Targeting RB1, Upregulating Interleukin-1 Receptor Accessory Protein (IL1RAP), and Activating p38 MAPK Pathway In Vitro. Mol Cell Proteomics. 2018;17:190-204 pubmed publisher..The data indicate that miR-4331 aggravates TGEV-induced mitochondrial damage by repressing expression of RB1, promoting IL1RAP, and activating p38 MAPK pathway. ..
- Tong D, Mu P, Dong Q, Zhao B, Liu W, Zhao J, et al. Immunological evaluation of SW-HSA conjugate on goats. Colloids Surf B Biointerfaces. 2007;58:61-7 pubmed..01) in the immune poisoning groups than that in the poisoning control group, and there was no significant difference (p>0.01) between the two immune poisoning groups within the poisoning experiment...
- Zhang H, Huang Y, Du Q, Luo X, Zhang L, Zhao X, et al. Porcine parvovirus infection induces apoptosis in PK-15 cells through activation of p53 and mitochondria-mediated pathway. Biochem Biophys Res Commun. 2015;456:649-55 pubmed publisher..This study may contribute to shed light on the molecular pathogenesis of PPV infection. ..
- Ding L, Huang Y, Du Q, Dong F, Zhao X, Zhang W, et al. TGEV nucleocapsid protein induces cell cycle arrest and apoptosis through activation of p53 signaling. Biochem Biophys Res Commun. 2014;445:497-503 pubmed publisher..Taken together, these results demonstrated that TGEV N protein might play an important role in TGEV infection-induced p53 activation and cell cycle arrest at the S and G2/M phases and apoptosis occurrence. ..