Genomes and Genes


Zheng Li


Affiliation: Northwest University
Country: China


  1. Zhong Y, Sun X, Zhang P, Qin X, Chen W, Guo Y, et al. Identification and localization of xylose-binding proteins as potential biomarkers for liver fibrosis/cirrhosis. Mol Biosyst. 2016;12:598-605 pubmed publisher
  2. Liang Y, Ma T, Thakur A, Yu H, Gao L, Shi P, et al. Differentially expressed glycosylated patterns of α-1-antitrypsin as serum biomarkers for the diagnosis of lung cancer. Glycobiology. 2015;25:331-40 pubmed publisher
    ..707). The present study indicates that glycosylated patterns of A1AT may serve as potential biomarkers for detection of lung cancer. Further studies in larger sample sizes are necessary to validate the clinical utility of these markers. ..
  3. Yu H, Zhong Y, Zhang Z, Liu X, Zhang K, Zhang F, et al. Characterization of proteins with Siaα2-3/6Gal-linked glycans from bovine milk and role of their glycans against influenza A virus. Food Funct. 2018;9:5198-5208 pubmed publisher
    ..Our findings will help to assess the potential application of sialylated glycoproteins in bovine milk against IAV. ..
  4. Qin Y, Zhong Y, Yang G, Ma T, Jia L, Huang C, et al. Profiling of concanavalin A-binding glycoproteins in human hepatic stellate cells activated with transforming growth factor-β1. Molecules. 2014;19:19845-67 pubmed publisher
    ..In conclusion, the results of this study may aid future investigations to find new molecular mechanisms involved in HSC activation and antifibrotic therapeutic targets. ..
  5. Wang X, Ning Y, Zhang F, Yu F, Tan W, Lei Y, et al. Gene expression signature in endemic osteoarthritis by microarray analysis. Int J Mol Sci. 2015;16:11465-81 pubmed publisher
    ..These results promote the further development of blood-based genetic biomarkers for detection of KBD. ..
  6. Zhong Y, Zhang J, Yu H, Zhang J, Sun X, Chen W, et al. Characterization and sub-cellular localization of GalNAc-binding proteins isolated from human hepatic stellate cells. Biochem Biophys Res Commun. 2015;468:906-12 pubmed publisher
  7. Yang G, Lu W, Yu D, Sun C, Guo J, Li Z, et al. Quantitative Analysis of Differential Proteome Expression in Epithelial-to-Mesenchymal Transition of Bladder Epithelial Cells Using SILAC Method. Molecules. 2016;21:84 pubmed publisher
    ..bladder cancer cells, revealing 16 proteins that displayed similar changes in the two situations. Studies are in progress to further characterize these 16 proteins and their biological functions in EMT. ..
  8. Qin Y, Zhong Y, Ma T, Wu F, Wu H, Yu H, et al. Alteration of liver glycopatterns during cirrhosis and tumor progression induced by HBV. Glycoconj J. 2016;33:125-36 pubmed publisher
  9. request reprint
    Qin Y, Wang Q, Zhong Y, Zhao F, Wu F, Wang Y, et al. Alteration of N-glycoproteins/N-glycosites in human hepatic stellate cells activated with transforming growth factor-?1. Cell Mol Biol (Noisy-le-grand). 2016;62:51-64 pubmed

More Information


  1. Liu X, Yu H, Qiao Y, Yang J, Shu J, Zhang J, et al. Salivary Glycopatterns as Potential Biomarkers for Screening of Early-Stage Breast Cancer. EBioMedicine. 2018;28:70-79 pubmed publisher
    ..902 in double-blind cohort. This study could contribute to the screening for patients with early-stage breast cancer based on precise alterations of salivary glycopatterns. ..
  2. Chen W, Xu Q, Zhong Y, Yu H, Shu J, Ma T, et al. Genetic variation and co-evolutionary relationship of RNA polymerase complex segments in influenza A viruses. Virology. 2017;511:193-206 pubmed publisher
    ..This global approach facilitates the establishment of a fast antiviral strategy and monitoring of viral variation. ..
  3. Qin Y, Zhong Y, Ma T, Zhang J, Yang G, Guan F, et al. A pilot study of salivary N-glycome in HBV-induced chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Glycoconj J. 2017;34:523-535 pubmed publisher
  4. Chen W, Zhong Y, Su R, Qi H, Deng W, Sun Y, et al. N-glycan profiles in H9N2 avian influenza viruses from chicken eggs and human embryonic lung fibroblast cells. J Virol Methods. 2017;249:10-20 pubmed publisher