Research Topics

Genomes and Genes


Fulin Chen


Affiliation: Northwest University
Country: China


  1. She M, Wang Z, Luo T, Yin B, Liu P, Liu J, et al. Fluorescent probes guided by a new practical performance regulation strategy to monitor glutathione in living systems. Chem Sci. 2018;9:8065-8070 pubmed publisher
    ..Moreover, the positively guided probes are excellent for imaging GSH distribution in living cells and mice. ..
  2. Cao J, Wu N, Han Y, Hou Q, Zhao Y, Pan Y, et al. DDX21 promotes gastric cancer proliferation by regulating cell cycle. Biochem Biophys Res Commun. 2018;505:1189-1194 pubmed publisher
    ..Taken together, these results revealed a novel role for DDX21 in the proliferation of gastric cancer cells via the Cyclin D1 and CDK2 pathways. Therefore, DDX21 can be used as a therapeutic target for gastric cancer. ..
  3. Sun M, Jiang M, Cui J, Liu W, Yin L, Xu C, et al. A novel approach for the cryodesiccated preservation of tissue-engineered skin substitutes with trehalose. Mater Sci Eng C Mater Biol Appl. 2016;60:60-66 pubmed publisher
    ..This novel approach enabled the preservation and transportation of TES at ambient temperature with a prolonged shelf time, which provides great advantages for the application of TES. ..
  4. Ma Z, Xin Z, Hu W, Jiang S, Yang Z, Yan X, et al. Forkhead box O proteins: Crucial regulators of cancer EMT. Semin Cancer Biol. 2018;50:21-31 pubmed publisher
    ..Collectively, the information compiled herein should serve as a comprehensive repository of information on this topic and should aid in the design of additional studies and the future development of FOXO proteins as therapeutic targets. ..
  5. Chen Z, Wei J, Zhu J, Liu W, Cui J, Li H, et al. Chm-1 gene-modified bone marrow mesenchymal stem cells maintain the chondrogenic phenotype of tissue-engineered cartilage. Stem Cell Res Ther. 2016;7:70 pubmed publisher
    ..Our findings defined an essential role for Chm-1 in maintaining chondrogenic phenotype and demonstrated that Chm-1 gene-modified MSCs may be used in cartilage tissue engineering. ..
  6. Rao Y, Cui J, Yin L, Liu W, Liu W, Sun M, et al. Preclinical study of mouse pluripotent parthenogenetic embryonic stem cell derivatives for the construction of tissue-engineered skin equivalent. Stem Cell Res Ther. 2016;7:156 pubmed
    ..Particularly, pESC derivatives avoid the limitations of political and ethical concerns, and provide a promising source for regenerative medicine. ..
  7. Tang J, Yu Y, Zheng H, Yin L, Sun M, Wang W, et al. ITRAQ-based quantitative proteomic analysis of Cynops orientalis limb regeneration. BMC Genomics. 2017;18:750 pubmed publisher
    ..This work indicated that significant proteome alternations occurred during salamander limb regeneration. The results may provide fundamental knowledge to understand the mechanism of limb regeneration. ..