Affiliation: Nankai University
- Zhang X, Zhang Z, Zhang Q, Zhang Q, Sun P, Xiang R, et al. ZEB1 confers chemotherapeutic resistance to breast cancer by activating ATM. Cell Death Dis. 2018;9:57 pubmed publisher..Collectively, our findings suggest that ZEB1 is a crucial determinant of chemotherapeutic resistance in breast cancer. ..
- Yang S, Du J, Wang Z, Yuan W, Qiao Y, Zhang M, et al. BMP-6 promotes E-cadherin expression through repressing deltaEF1 in breast cancer cells. BMC Cancer. 2007;7:211 pubmed....
- Yang S, Du J, Wang Z, Yan J, Yuan W, Zhang J, et al. Dual mechanism of deltaEF1 expression regulated by bone morphogenetic protein-6 in breast cancer. Int J Biochem Cell Biol. 2009;41:853-61 pubmed publisher..Our study has provided novel findings of a dual mechanism for BMP-6-regulated deltaEF1 expression in breast cancer cells, involving cross-talks between AP-1-mediated transcriptional repression and miRs-mediated translational inhibition. ..
- Yang S, Liu L, Xu P, Yang Z. MKL1 inhibits cell cycle progression through p21 in podocytes. BMC Mol Biol. 2015;16:1 pubmed publisher..Our observations demonstrate that MKL1 has physiological roles in the maturation and development of podocytes, and thus its misregulation might lead to glomerular and renal dysfunction. ..
- Wu C, Liu Y, Gu X, Zhu T, Yang S, Sun W. LMO2 blocks the UBA6-USE1 interaction and downstream FAT10ylation by targeting the ubiquitin fold domain of UBA6. Biochem Biophys Res Commun. 2016;478:1442-8 pubmed publisher..Taken together, this study revealed a novel function of LMO2 involving in the regulatory hierarchy of UBA6-USE1-FAT10ylation pathway by targeting the E1 enzyme UBA6. ..
- Luo D, Wang G, Shen W, Zhao S, Zhou W, Wan L, et al. Clinical significance and functional validation of PPA1 in various tumors. Cancer Med. 2016;5:2800-2812 pubmed publisher..PPA1 expression is significantly higher in many tumors, especially those of lung and ovarian origin, which suggests that PPA1 plays an important role in carcinogenesis and in the development of some tumors. ..