Lin Fu Zhou

Summary

Affiliation: Nanjing Medical University
Country: China

Publications

  1. doi Unusual life-threatening Rosai-Dorfman disease of the trachea: role of NF-κB
    Lin Fu Zhou
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China
    Thorax 65:927-9. 2010
  2. pmc Arsenic trioxide, a potent inhibitor of NF-kappaB, abrogates allergen-induced airway hyperresponsiveness and inflammation
    Lin Fu Zhou
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China
    Respir Res 7:146. 2006
  3. doi [Induction of monocyte-derived dendritic cell differentiation by asthmatic serum in a transendothelial trafficking model]
    Lin Fu Zhou
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, China
    Zhonghua Jie He He Hu Xi Za Zhi 34:169-73. 2011
  4. ncbi Effects of adenoviral gene transfer of mutated IkappaBalpha, a novel inhibitor of NF-kappaB, on human monocyte-derived dendritic cells
    Lin Fu Zhou
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    Acta Pharmacol Sin 27:609-16. 2006
  5. doi Inhibitory effects of astragaloside IV on ovalbumin-induced chronic experimental asthma
    Qiang Du
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
    Can J Physiol Pharmacol 86:449-57. 2008
  6. ncbi Increased RhoGDI2 and peroxiredoxin 5 levels in asthmatic murine model of beta2-adrenoceptor desensitization: a proteomics approach
    Hua Liu
    Department of Respiratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China
    Chin Med J (Engl) 121:355-62. 2008
  7. ncbi Targeted NF-kappaB inhibition of asthmatic serum-mediated human monocyte-derived dendritic cell differentiation in a transendothelial trafficking model
    Xiao Yan Gu
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    Cell Immunol 260:14-20. 2009
  8. ncbi Expression of surface markers on peripheral CD4+CD25high T cells in patients with atopic asthma: role of inhaled corticosteroid
    Qian Zhang
    Department of Respiratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China
    Chin Med J (Engl) 121:205-12. 2008
  9. doi Interferon-λ mediates oral tolerance and inhibits antigen-specific, T-helper 2 cell-mediated inflammation in mouse intestine
    Shao Heng He
    Clinical Experimental Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China
    Gastroenterology 141:249-58, 258.e1-2. 2011
  10. ncbi Adenovirus-mediated overexpression of novel mutated IkappaBalpha inhibits nuclear factor kappaB activation in endothelial cells
    Lin Fu Zhou
    Department of Respiratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    Chin Med J (Engl) 118:1422-8. 2005

Collaborators

Detail Information

Publications25

  1. doi Unusual life-threatening Rosai-Dorfman disease of the trachea: role of NF-κB
    Lin Fu Zhou
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China
    Thorax 65:927-9. 2010
    ..The patient remains well with no evidence of progression without treatment. Histological confirmation should be sought in all cases as the clinical manifestation of RDD is similar to asthma or lung carcinoma...
  2. pmc Arsenic trioxide, a potent inhibitor of NF-kappaB, abrogates allergen-induced airway hyperresponsiveness and inflammation
    Lin Fu Zhou
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China
    Respir Res 7:146. 2006
    ..Here we provide evidence that As2O3 abrogates allergen (OVA)-induced airway eosinophilia by modulating the expression of IkappaBalpha, an NF-kappaB inhibitory protein, and decreases the airway hyperresponsiveness...
  3. doi [Induction of monocyte-derived dendritic cell differentiation by asthmatic serum in a transendothelial trafficking model]
    Lin Fu Zhou
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, China
    Zhonghua Jie He He Hu Xi Za Zhi 34:169-73. 2011
    ..To explore the effect of asthmatic and healthy serum on differentiation and function of monocyte-derived dendritic cells (MDDC) in a transendothelial trafficking model...
  4. ncbi Effects of adenoviral gene transfer of mutated IkappaBalpha, a novel inhibitor of NF-kappaB, on human monocyte-derived dendritic cells
    Lin Fu Zhou
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    Acta Pharmacol Sin 27:609-16. 2006
    ..To investigate the effects of adenoviral gene transfer of IkappaBalpha mutant (IkappaBalphaM), a novel inhibitor of nuclear factor kappaB (NF-kappaB), on apoptosis, phenotype and function of human monocyte-derived dendritic cells (DC)...
  5. doi Inhibitory effects of astragaloside IV on ovalbumin-induced chronic experimental asthma
    Qiang Du
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
    Can J Physiol Pharmacol 86:449-57. 2008
    ..These data indicate that astragaloside IV may mitigate the development of characteristic features in chronic experimental asthma...
  6. ncbi Increased RhoGDI2 and peroxiredoxin 5 levels in asthmatic murine model of beta2-adrenoceptor desensitization: a proteomics approach
    Hua Liu
    Department of Respiratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China
    Chin Med J (Engl) 121:355-62. 2008
    ..It is not clear whether there are other mechanisms. This study aimed to investigate potential mechanisms of beta(2)AR desensitization...
  7. ncbi Targeted NF-kappaB inhibition of asthmatic serum-mediated human monocyte-derived dendritic cell differentiation in a transendothelial trafficking model
    Xiao Yan Gu
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    Cell Immunol 260:14-20. 2009
    ..These results suggest that AdIkappaBalphaM-transferred MDDC are at a more immature stage which is beneficial to augment the immune tolerance in asthma...
  8. ncbi Expression of surface markers on peripheral CD4+CD25high T cells in patients with atopic asthma: role of inhaled corticosteroid
    Qian Zhang
    Department of Respiratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China
    Chin Med J (Engl) 121:205-12. 2008
    ..This study sought to characterize the expression of surface markers on peripheral blood mononuclear cells-derived Tregs in patients with atopic asthma and healthy subjects, and to investigate the effect of inhaled corticosteroid on them...
  9. doi Interferon-λ mediates oral tolerance and inhibits antigen-specific, T-helper 2 cell-mediated inflammation in mouse intestine
    Shao Heng He
    Clinical Experimental Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China
    Gastroenterology 141:249-58, 258.e1-2. 2011
    ..We investigated the role and the mechanism of IFN-λ in the development of oral tolerance and its effect on antigen-induced, T-helper (Th)-2 cell-mediated inflammation in the intestine...
  10. ncbi Adenovirus-mediated overexpression of novel mutated IkappaBalpha inhibits nuclear factor kappaB activation in endothelial cells
    Lin Fu Zhou
    Department of Respiratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    Chin Med J (Engl) 118:1422-8. 2005
    ....
  11. ncbi Toll-like receptors: function and roles in asthma
    Lin Fu Zhou
    Department of Respiratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    Chin Med J (Engl) 117:1709-15. 2004
  12. doi Eosinophil-derived interferon-lambda contributes to initiation of allergen-related inflammation in the intestine
    Shao Heng He
    Clinical Experimental Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    Cytokine 58:186-92. 2012
    ..The present study aimed to elucidate the mechanism by which the eosinophil-derived interferon (IFN)-lambda induced the gut epithelial barrier dysfunction...
  13. ncbi Pulmonary major histocompatibility complex expression pattern is suggestive of the characteristics of airway antigen
    Yi Zhu
    Department of Respiratory Disease, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Chin Med J (Engl) 119:688-91. 2006
  14. ncbi [Inhibitory effects of apigenin on the expression of GATA-3 and Th2 cytokines in asthmatic mice]
    Ling ling Pang
    Department of Respiratory Diseases, The First Affiliated Hospital, Nanjing Medical University, Nanjing
    Zhongguo Zhong Xi Yi Jie He Za Zhi 30:383-7. 2010
    ..To investigate the inhibitory effects and mechanism of apigenin (APG) on dominant response of Th2 cells in asthma model of mice...
  15. ncbi High-sensitivity C-reactive protein: a predicative marker in severe asthma
    Fen Hong Qian
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China
    Respirology 13:664-9. 2008
    ..This study investigated whether hs-CRP is associated with asthma severity as well as with other clinical indices of asthma activity (pulmonary function, total serum IgE, and peripheral blood eosinophil counts)...
  16. doi Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma
    Qiang Du
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China
    Clin Exp Pharmacol Physiol 36:43-8. 2009
    ..4. In summary, the results of the present study indicate that imiquimod may attenuate the progression of airway inflammation and remodelling, providing potential in the treatment of asthma...
  17. ncbi The value of assessment tests in patients with acute exacerbation of chronic obstructive pulmonary disease
    Yun Feng Zhao
    Department of Respiratory Medicine Y FZ, Pudong New Area Gongli Hospital, Shanghai, China Department of Respiratory Medicine Y PJ, Hospital of The PLA, Wuxi, China Department of Respiratory Medicine L FZ, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China and Department of Respiratory Medicine, Institute of Respiratory Medicine X LW, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    Am J Med Sci 347:393-9. 2014
    ..Hence, high CAT scores and serum copeptin levels link with recurrence of acute exacerbation and all-cause mortality during 6 months in patients with acute exacerbation of COPD...
  18. ncbi [Flexible bronchoscopic intervention for endobronchial hamartoma]
    Ji wang Wang
    Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China Email
    Zhonghua Jie He He Hu Xi Za Zhi 36:963-7. 2013
    ..To evaluate the effectiveness and safety of interventional treatment in the removal of endobronchial hamartoma by flexible bronchoscopy...
  19. ncbi [DNAzymes in vitro inhibit the expression of hepatitis B virus genes]
    Jian er Wo
    Institute of Infectious Diseases, The First Affiliated Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310003, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 32:112-5. 2003
    ..To evaluate the inhibition effects of DNAzymes specific to Hepatitis B Virus(HBV) s gene and e gene on the expressions of Hepatitis B surface antigen(HBsAg) and Hepatitis B e antigen(HBeAg)...
  20. ncbi [Association of genetic polymorphisms in glutathione S-transferases M1 with hepatitis beta-related hepatocellular carcinoma]
    Man hua Zhu
    Institute of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:126-30. 2005
    ..To investigate the association of genetic polymorphisms in glutathione S-transferases(GST) M1 with hepatitis beta-related hepatocellular carcinoma (HCC)...
  21. ncbi [Inhibition of binding peptides on replication of duck hepatitis B virus]
    Hong yu Jia
    Institute of Infectious Disease, The First Affiliated Hospital, Key Laboratory of Infectious Disease Ministry of Health, College of Medicine, Zhejiang University, Hangzhou 310003, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:116-20. 2005
    ..To study the inhibitory effect of binding peptides on duck hepatitis B virus (DHBV) replication in duck hepatocytes...
  22. ncbi [Effect of arsenic trioxide on apoptosis of pulmonary eosinophile in asthmatic guinea-pigs]
    Lin Fu Zhou
    First Hospital Affiliated to Nanjing Medical University, Nanjing 210029
    Zhongguo Zhong Xi Yi Jie He Za Zhi 22:292-4. 2002
    ..To study the effect and mechanism of arsenic trioxide (As2O3) on apoptosis of pulmonary eosinophiles (PE) in asthmatic guinea-pigs...
  23. ncbi Preparation and characterization of a novel exendin-4 human serum albumin fusion protein expressed in Pichia pastoris
    Yan Shan Huang
    Department of Cell Biology, School of Medicine, Zhejiang University, Hangzhou, China
    J Pept Sci 14:588-95. 2008
    ..Pharmacokinetics studies in cynomologus monkeys also showed that rEx-4/HSA had a much longer plasma half-life. Therefore, rEx-4/HSA fusion protein could potentially be used as a new recombinant biodrug for type 2 diabetes therapy...
  24. ncbi Wilson disease: identification of two novel mutations and clinical correlation in Eastern Chinese patients
    Sheng Ye
    Department of Pediatrics, Child Hospital, Zhejiang University, Hangzhou 310005, Zhejiang Province, China
    World J Gastroenterol 13:5147-50. 2007
    ..To study mutations in the P-type ATPase (ATP7B) gene responsible for Wilson disease (WD) in the Eastern Chinese population, and the possible correlation of specific mutations with clinical characteristics...
  25. pmc Immunomodulatory function of orally administered thymosin alpha1
    Xiang Ming Chen
    Department of Anesthesiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 6:873-6. 2005
    ..To investigate the immunological function of a yeast expression system for thymosin alpha1 (Talpha1)...