Xiaowei Zhang


Affiliation: Nanjing University
Country: China


  1. Su G, Zhang X, Giesy J, Musarrat J, Saquib Q, Alkhedhairy A, et al. Comparison on the molecular response profiles between nano zinc oxide (ZnO) particles and free zinc ion using a genome-wide toxicogenomics approach. Environ Sci Pollut Res Int. 2015;22:17434-42 pubmed publisher
    ..Our results underscore the importance of understanding the adverse effects elicited by nano-ZnO after entering aquatic environment. ..
  2. Xie Y, Zhang X, Yang J, Kim S, Hong S, Giesy J, et al. eDNA-based bioassessment of coastal sediments impacted by an oil spill. Environ Pollut. 2018;238:739-748 pubmed publisher
    ..eDNA metabarcoding can provide a powerful tool for assessing effects of anthropogenic pollution, such as oil spills on sediment communities and its long-term trends in coastal marine environments. ..
  3. Xie Y, Floehr T, Zhang X, Xiao H, Yang J, Xia P, et al. In situ microbiota distinguished primary anthropogenic stressor in freshwater sediments. Environ Pollut. 2018;239:189-197 pubmed publisher
    ..The observed responses of microbial community provided supplementary evidence to support that the AhR-active pollutants, such as PAHs, were the primary stressors of the aquatic community in TGR area. ..
  4. Guan M, Su G, Giesy J, Zhang X. Classification and toxicity mechanisms of novel flame retardants (NFRs) based on whole genome expression profiling. Chemosphere. 2016;144:2150-7 pubmed publisher
    ..The results of this study demonstrated the utility of the E. coli, whole-cell assay for determining mechanisms of toxic action of chemicals. ..
  5. Li J, Su L, Wei F, Yang J, Jin L, Zhang X. Bioavailability-based assessment of aryl hydrocarbon receptor-mediated activity in Lake Tai Basin from Eastern China. Sci Total Environ. 2016;544:987-94 pubmed publisher
  6. Ma L, Xie Y, Han Z, Giesy J, Zhang X. Responses of earthworms and microbial communities in their guts to Triclosan. Chemosphere. 2017;168:1194-1202 pubmed publisher
    ..Thus, rapid genomic measures of gut flora can be used as indicators to assess adverse effects of chemicals on earthworms. ..
  7. Jung D, Guan M, Lee S, Kim C, Shin H, Hong S, et al. Searching for novel modes of toxic actions of oil spill using E. coli live cell array reporter system - A Hebei Spirit oil spill study. Chemosphere. 2017;169:669-677 pubmed publisher
    ..Toxicological implications of such observations deserve further examination. Overall, LCA is a promising tool for screening samples and identifying potential modes of toxicities of environmental samples associated with oil spills. ..
  8. Wang P, Du Z, Gao S, Zhang X, Giesy J. Impairment of reproduction of adult zebrafish (Danio rerio) by binary mixtures of environmentally relevant concentrations of triclocarban and inorganic mercury. Ecotoxicol Environ Saf. 2016;134P1:124-132 pubmed publisher
  9. Shi W, Yu N, Jiang X, Han Z, Wang S, Zhang X, et al. Influence of blooms of phytoplankton on concentrations of hydrophobic organic chemicals in sediments and snails in a hyper-eutrophic, freshwater lake. Water Res. 2017;113:22-31 pubmed publisher
    ..Thus, in Tai Lake, the fate and distribution of persistent and biodegradable contaminants in sediments and snails is influenced by blooms of phytoplankton, which should be included in models of environmental fates of contaminants. ..

More Information


  1. Guan M, Zhang X. Functional genomic assessment of 2, 2-bis (bromomethyl)-1, 3-propanediol induced cytotoxicity in a single-gene knockout library of E. coli. Chemosphere. 2017;185:582-588 pubmed publisher
    ..Overall, the functional genomic screening approach presented here provides a great tool to assess the cellular toxicological mechanism of environmental chemicals. ..
  2. Guan M, Fang W, Ullah S, Zhang X, Saquib Q, Al Khedhairy A. Functional genomics assessment of narcotic and specific acting chemical pollutants using E. coli. Environ Pollut. 2018;232:146-153 pubmed publisher
    ..The E. coli functional genomic approach presented here has shown great potential not only for the molecular mechanistic screening of chemicals, rather it can discriminate chemicals based on their mode-of-action. ..