Hongxia Yu


Affiliation: Nanjing University
Country: China


  1. Hu X, Shi W, Yu N, Jiang X, Wang S, Giesy J, et al. Bioassay-directed identification of organic toxicants in water and sediment of Tai Lake, China. Water Res. 2015;73:231-41 pubmed publisher
    ..Bioassay-directed analysis should be added for screening for the presence of priority organic pollutants in environmental media. ..
  2. Yu N, Wang X, Zhang B, Yang J, Li M, Li J, et al. Distribution of perfluorooctane sulfonate isomers and predicted risk of thyroid hormonal perturbation in drinking water. Water Res. 2015;76:171-80 pubmed publisher
    ..The results revealed that the PFOS isomer profile and the toxicity of individual PFOS isomers were important factors in health risk assessment of PFOS and should be considered in the future risk assessments. ..
  3. Su G, Zhang X, Giesy J, Musarrat J, Saquib Q, Alkhedhairy A, et al. Comparison on the molecular response profiles between nano zinc oxide (ZnO) particles and free zinc ion using a genome-wide toxicogenomics approach. Environ Sci Pollut Res Int. 2015;22:17434-42 pubmed publisher
    ..Our results underscore the importance of understanding the adverse effects elicited by nano-ZnO after entering aquatic environment. ..
  4. Shi W, Deng D, Wang Y, Hu G, Guo J, Zhang X, et al. Causes of endocrine disrupting potencies in surface water in East China. Chemosphere. 2016;144:1435-42 pubmed publisher
    ..In most surface waters studied, PAEs contributed little of the AR-AntEQ, but the frequently detected octylphenol, nonylphenol and benzo[a]pyrene might be responsible. ..
  5. Wu Y, Doering J, Ma Z, Tang S, Liu H, Zhang X, et al. Identification of androgen receptor antagonists: In vitro investigation and classification methodology for flavonoid. Chemosphere. 2016;158:72-9 pubmed publisher
    ..This methodology could be used as a "proof of concept" to identify inactive anti-androgenic flavonoids, as well could be beneficial for rapid risk assessment and regulation of multiple new chemicals for androgenicity. ..
  6. Wang X, Zhang X, Xia P, Zhang J, Wang Y, Zhang R, et al. A high-throughput, computational system to predict if environmental contaminants can bind to human nuclear receptors. Sci Total Environ. 2017;576:609-616 pubmed publisher
  7. Wu Y, Su G, Tang S, Liu W, Ma Z, Zheng X, et al. The combination of in silico and in vivo approaches for the investigation of disrupting effects of tris (2-chloroethyl) phosphate (TCEP) toward core receptors of zebrafish. Chemosphere. 2017;168:122-130 pubmed publisher
    ..These results exhibited the need for further studies to evaluate the potential health risks of TCEP to human infants/children due to its high concentration in Chinese rivers (up to 3700 ng/L) and potential for human exposure. ..
  8. Shi W, Yu N, Jiang X, Han Z, Wang S, Zhang X, et al. Influence of blooms of phytoplankton on concentrations of hydrophobic organic chemicals in sediments and snails in a hyper-eutrophic, freshwater lake. Water Res. 2017;113:22-31 pubmed publisher
    ..Thus, in Tai Lake, the fate and distribution of persistent and biodegradable contaminants in sediments and snails is influenced by blooms of phytoplankton, which should be included in models of environmental fates of contaminants. ..
  9. Liu H, Ma Z, Zhang T, Yu N, Su G, Giesy J, et al. Pharmacokinetics and effects of tetrabromobisphenol a (TBBPA) to early life stages of zebrafish (Danio rerio). Chemosphere. 2018;190:243-252 pubmed publisher
    ..5 × 102 μg TBBPA/L significantly down-regulated expression of ThRα and associated genes, ncor, c1d, ncoa2, ncoa3, and ncoa4, in the AR pathway and of er2a and er2b genes in the ER pathway. ..

More Information


  1. Wu Y, Shi W, Xia P, Zhang X, Yu H. Qualitative and quantitative simulation of androgen receptor antagonists: A case study of polybrominated diphenyl ethers. Sci Total Environ. 2017;603-604:495-501 pubmed publisher
  2. Han Z, Li Y, Zhang S, Song N, Xu H, Dang Y, et al. Prenatal transfer of decabromodiphenyl ether (BDE-209) results in disruption of the thyroid system and developmental toxicity in zebrafish offspring. Aquat Toxicol. 2017;190:46-52 pubmed publisher
    ..These results suggest that exposure of parent zebrafish to BDE-209 can cause developmental toxicity in offspring and disruption of the thyroid endocrine system of offspring. ..