Jin Wang

Summary

Affiliation: Nanjing University
Country: China

Publications

  1. pmc Distance and helical phase dependence of synergistic transcription activation in cis-regulatory module
    Qilai Huang
    The State Key Laboratory of Pharmaceutical Biotechnology and Affiliated Stomatological Hospital, Nanjing University, Nanjing, People s Republic of China
    PLoS ONE 7:e31198. 2012
  2. pmc Regulatory coordination of clustered microRNAs based on microRNA-transcription factor regulatory network
    Jin Wang
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology
    BMC Syst Biol 5:199. 2011
  3. pmc A mutation degree model for the identification of transcriptional regulatory elements
    Changqing Zhang
    State Key Laboratory of Pharmaceutical Biotechnology, School of Life Science, Nanjing University, Nanjing 210093, China
    BMC Bioinformatics 12:262. 2011
  4. pmc MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
    Huaiqiu Zhu
    State Key Lab for Turbulence and Complex Systems and Department of Biomedical Engineering, Peking University, Beijing 100871, China
    BMC Bioinformatics 8:97. 2007
  5. pmc Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA
    Lin Zhang
    Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China
    Cell Res 22:107-26. 2012
  6. pmc MiRmat: mature microRNA sequence prediction
    Chenfeng He
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Science, Nanjing University, Nanjing, China
    PLoS ONE 7:e51673. 2012
  7. doi request reprint Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
    Xi Chen
    Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210093, China
    Cell Res 18:997-1006. 2008
  8. ncbi request reprint Hypoxia induces PGC-1α expression and mitochondrial biogenesis in the myocardium of TOF patients
    Lingyun Zhu
    Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China
    Cell Res 20:676-87. 2010
  9. pmc InterMitoBase: an annotated database and analysis platform of protein-protein interactions for human mitochondria
    Zuguang Gu
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Science, Nanjing University, Nanjing 210093, China
    BMC Genomics 12:335. 2011
  10. pmc Gene regulation is governed by a core network in hepatocellular carcinoma
    Zuguang Gu
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Science, Nanjing University, Nanjing 210093, China
    BMC Syst Biol 6:32. 2012

Collaborators

Detail Information

Publications18

  1. pmc Distance and helical phase dependence of synergistic transcription activation in cis-regulatory module
    Qilai Huang
    The State Key Laboratory of Pharmaceutical Biotechnology and Affiliated Stomatological Hospital, Nanjing University, Nanjing, People s Republic of China
    PLoS ONE 7:e31198. 2012
    ..These results could be used to understand synergistic transcription activation anew and to aid the development of predictive models for the identification of cis-regulatory elements...
  2. pmc Regulatory coordination of clustered microRNAs based on microRNA-transcription factor regulatory network
    Jin Wang
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology
    BMC Syst Biol 5:199. 2011
    ..This implies a coordinated regulation mode exerted by clustered miRNAs. However, how the clustered miRNAs coordinate their regulations on large scale gene expression is still unclear...
  3. pmc A mutation degree model for the identification of transcriptional regulatory elements
    Changqing Zhang
    State Key Laboratory of Pharmaceutical Biotechnology, School of Life Science, Nanjing University, Nanjing 210093, China
    BMC Bioinformatics 12:262. 2011
    ....
  4. pmc MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
    Huaiqiu Zhu
    State Key Lab for Turbulence and Complex Systems and Department of Biomedical Engineering, Peking University, Beijing 100871, China
    BMC Bioinformatics 8:97. 2007
    ..It continues to be interesting to develop new ab initio algorithms which not only accurately predict genes, but also facilitate comparative studies of prokaryotic genomes...
  5. pmc Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA
    Lin Zhang
    Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China
    Cell Res 22:107-26. 2012
    ..These findings demonstrate that exogenous plant miRNAs in food can regulate the expression of target genes in mammals...
  6. pmc MiRmat: mature microRNA sequence prediction
    Chenfeng He
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Science, Nanjing University, Nanjing, China
    PLoS ONE 7:e51673. 2012
    ....
  7. doi request reprint Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
    Xi Chen
    Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210093, China
    Cell Res 18:997-1006. 2008
    ..Through these analyses, we conclude that serum miRNAs can serve as potential biomarkers for the detection of various cancers and other diseases...
  8. ncbi request reprint Hypoxia induces PGC-1α expression and mitochondrial biogenesis in the myocardium of TOF patients
    Lingyun Zhu
    Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China
    Cell Res 20:676-87. 2010
    ....
  9. pmc InterMitoBase: an annotated database and analysis platform of protein-protein interactions for human mitochondria
    Zuguang Gu
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Science, Nanjing University, Nanjing 210093, China
    BMC Genomics 12:335. 2011
    ..Consequently, the development of a database that provides the entire protein interaction map of the human mitochondrion is urgently required...
  10. pmc Gene regulation is governed by a core network in hepatocellular carcinoma
    Zuguang Gu
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Science, Nanjing University, Nanjing 210093, China
    BMC Syst Biol 6:32. 2012
    ..Thus, analysis of the mechanism of molecule interactions in the context of gene regulatory networks can reveal specific sub-networks that lead to the development of HCC...
  11. pmc Centrality-based pathway enrichment: a systematic approach for finding significant pathways dominated by key genes
    Zuguang Gu
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Science, Nanjing University, Nanjing, 210093, China
    BMC Syst Biol 6:56. 2012
    ..Pathways resemble networks with complicated structures, but most of the existing pathway enrichment tools ignore topological information embedded within pathways, which limits their applicability...
  12. pmc The evolutionary trajectory of mitochondrial carrier family during metazoan evolution
    Ming Gong
    Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
    BMC Evol Biol 10:282. 2010
    ..However, the evolutionary study of substrate transport of MCF does not mean that all the concrete structures of mitochondrial carriers (MCs) must first be gained...
  13. ncbi request reprint CePa: an R package for finding significant pathways weighted by multiple network centralities
    Zuguang Gu
    The State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Science, Department of Physics, Nanjing University, Nanjing 210093, China
    Bioinformatics 29:658-60. 2013
    ..CePa has been evaluated with high performance on real-world data, and it can provide more information directly related to current biological problems...
  14. pmc Characterization of regulatory features of housekeeping and tissue-specific regulators within tissue regulatory networks
    Pengping Li
    The State Key Laboratory of Pharmaceutical Biotechnology, Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, School of Life Science, Nanjing University, Nanjing, China
    BMC Syst Biol 7:112. 2013
    ..For example, how is the expression of so many genes regulated by limited cohorts of regulators and how are genes differentially expressed in different tissues despite the genetic code being the same in all tissues?..
  15. pmc Identification and characterization of novel amphioxus microRNAs by Solexa sequencing
    Xi Chen
    Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Hankou Road, Nanjing, Jiangsu 210093, PR China
    Genome Biol 10:R78. 2009
    ..While the number of known human and murine miRNAs is continuously increasing, information regarding miRNAs from other species such as amphioxus remains limited...
  16. doi request reprint In vitro evidence suggests that miR-133a-mediated regulation of uncoupling protein 2 (UCP2) is an indispensable step in myogenic differentiation
    Xi Chen
    Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
    J Biol Chem 284:5362-9. 2009
    ..Taken together, our current work delineates a novel regulatory network employing MyoD, microRNA, and uncoupling proteins to fine-tune the balance between muscle differentiation and proliferation during myogenesis...
  17. ncbi request reprint Fusion protein between protein ZZ and red fluorescent protein DsRed and its application to immunoassays
    Qi Lai Huang
    The State Key Laboratory of Pharmaceutical Biotechnology and Department of Biochemistry, College of Life Sciences, Nanjing University, Nanjing 210093, People s Republic of China
    Biotechnol Appl Biochem 43:121-7. 2006
    ..Our results indicate that ZZ-DsRed shows a wide and promising application potential in immunological detection as a substitute for fluorescent or HRP-conjugated anti-IgGs...