Research Topics
| Shi Yang PanSummaryAffiliation: Nanjing Medical University Country: China Publications
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Detail Information
Publications
The property of methylated APC gene promotor and its influence on lung cancer cell lineShiyang Pan
Department of Laboratory Medicine of the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China
Biomed Pharmacother 63:463-8. 2009..Inherited monoallelic methylation of the APC gene may play an important role in lung cancer. Demethylation of the APC gene by 5-aza-dC may be useful for the treatment of lung cancer...
The study on newly developed McAb NJ001 specific to non-small cell lung cancer and its biological characteristicsShiyang Pan
Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
PLoS ONE 7:e33009. 2012..NJ001 is of great value concerning immunodiagnostics and immunotherapy for NSCLC and holds promise for further research regarding the mechanism underlying tumor progression of NSCLC...
Can plasma DNA monitoring be employed in personalized chemotherapy for patients with advanced lung cancer?Shiyang Pan
Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Biomed Pharmacother 66:131-7. 2012..The quantification of plasma DNA is a sensitive indicator of chemotherapeutic efficacy in advanced lung cancer patients, and it can be useful in predicting response to therapy and guiding medication...
[Methylation quantification of adenomatous polyposis coli (APC) gene promoter in plasma of lung cancer patients]Shi Yang Pan
Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, PR China
Ai Zheng 28:384-9. 2009..This study was to develop a real-time quantitative methylation specific PCR (real-time QMSP) method, and detect the methylation of APC gene promoter in plasma of lung cancer patients...
[Research and development of medical case database: a novel medical case information system integrating with biospecimen management]Shiyang Pan
Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 27:302-6, 319. 2010..It realizes synthesized and dynamic management of medical case and biospecimen, which may be considered as a new management platform...
Double recognition of oligonucleotide and protein in the detection of DNA methylation with surface plasmon resonance biosensorsShiyang Pan
Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
Biosens Bioelectron 26:850-3. 2010..It will improve our ability to detect DNA methylation specifically and rapidly, and promote our understanding of the role of DNA methylation in gene regulation and diseases...
[Dynamic monitoring of plasma circulating DNA in patients with acute myeloid leukemia and its clinical significance]Ye Jiang
Department of Laboratory Medicine, Nanjing Medical University, Nanjing, Jiangsu Province, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 20:53-6. 2012..3%) relapsed patients, but no increase was found in 22 out of 25 (88.0%) non-relapsed patients. It is concluded that the quantification of plasma DNA may be useful for evaluating therapeutic effects and monitoring relapse in AML patients...
[Study of quantitative detection of circulating DNA in the plasma of patients with cervical lesion]Hong Wang
Department of Laboratory Medicine, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
Zhonghua Fu Chan Ke Za Zhi 46:501-4. 2011..To quantitatively detect circulating DNA levels in the plasma of patients withcervical lesion and to determine the value for diagnosis of cervical lesion and cervical cancer...
[The level of peripheral circular DNA in patients with hand foot and mouth disease]Zhao xia Zhao
Department of Laboratory Medicine, Fifth Hospital of Shijiazhuang, Shijiazhuang 050021, China
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 25:483-5. 2011..To determine the circular DNA level of patients with hand foot and mouth disease (HFMD) and evaluate its potential clinical value...
Plasma Vitamin D Levels And Vitamin D Receptor Polymorphisms Are Associated with Survival of Non-small Cell Lung CancerYao Liu
Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 210029, China
Chin J Cancer Res 23:33-7. 2011..Thus we hypothesized that plasma vitamin D levels and single nucleotide polymorphisms (SNPs) in may be of prognostic significance in non-small cell lung cancer (NSCLC)...
Polymorphisms in EGFR and VEGF contribute to non-small-cell lung cancer survival in a Chinese populationJing Dong
Department of Epidemiology and Biostatistics, Cancer Center, Nanjing Medical University, 140 Hanzhong Road, Nanjing 210029, China
Carcinogenesis 31:1080-6. 2010..56, 95% CI = 0.39-0.83). Stepwise COX regression analyses suggested that EGFR rs373506, rs759165 and rs6958497 may be independent candidate biomarkers to predict NSCLC survival in this population...
Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosisWen Gao
Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 210029
Biomed Pharmacother 64:399-408. 2010..MiRNA expression profiles may become useful biomarkers for cancer diagnostics, prognosis and prediction of response to treatment, and it could be a powerful tool for cancer prevention and therapeutics...
