Shi Yang Pan

Summary

Affiliation: Nanjing Medical University
Country: China

Publications

  1. doi The property of methylated APC gene promotor and its influence on lung cancer cell line
    Shiyang Pan
    Department of Laboratory Medicine of the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China
    Biomed Pharmacother 63:463-8. 2009
  2. pmc Downregulation of IFNG in CD4(+) T cells in lung cancer through hypermethylation: a possible mechanism of tumor-induced immunosuppression
    Fang Wang
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China National Key Clinical Department of Laboratory Medicine, Nanjing, China
    PLoS ONE 8:e79064. 2013
  3. pmc Prevalence and trends of aminoglycoside resistance in Shigella worldwide, 1999-2010
    Bing Gu
    Department of Laboratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China National Key Clinical, Department of Laboratory Medicine, Nanjing, Jiangsu 210029, China
    J Biomed Res 27:103-15. 2013
  4. pmc The study on newly developed McAb NJ001 specific to non-small cell lung cancer and its biological characteristics
    Shiyang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    PLoS ONE 7:e33009. 2012
  5. doi Can plasma DNA monitoring be employed in personalized chemotherapy for patients with advanced lung cancer?
    Shiyang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    Biomed Pharmacother 66:131-7. 2012
  6. ncbi [Methylation quantification of adenomatous polyposis coli (APC) gene promoter in plasma of lung cancer patients]
    Shi Yang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, PR China
    Ai Zheng 28:384-9. 2009
  7. ncbi [Research and development of medical case database: a novel medical case information system integrating with biospecimen management]
    Shiyang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 27:302-6, 319. 2010
  8. doi Double recognition of oligonucleotide and protein in the detection of DNA methylation with surface plasmon resonance biosensors
    Shiyang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
    Biosens Bioelectron 26:850-3. 2010
  9. ncbi [Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines]
    Li Xia Zhang
    Center of Clinical Laboratory, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, P R China
    Ai Zheng 26:576-80. 2007
  10. ncbi [Quantitative detection of APC/RASSF1A promoter methylation in the plasma of patients with cervical diseases]
    Hong Wang
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Fu Chan Ke Za Zhi 48:929-34. 2013

Collaborators

Detail Information

Publications17

  1. doi The property of methylated APC gene promotor and its influence on lung cancer cell line
    Shiyang Pan
    Department of Laboratory Medicine of the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China
    Biomed Pharmacother 63:463-8. 2009
    ..Inherited monoallelic methylation of the APC gene may play an important role in lung cancer. Demethylation of the APC gene by 5-aza-dC may be useful for the treatment of lung cancer...
  2. pmc Downregulation of IFNG in CD4(+) T cells in lung cancer through hypermethylation: a possible mechanism of tumor-induced immunosuppression
    Fang Wang
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China National Key Clinical Department of Laboratory Medicine, Nanjing, China
    PLoS ONE 8:e79064. 2013
    ..Our study suggests that interaction between lung cancer cells and CD4(+) T cells induces DNMT expression and IFNG promoter hypermethylation in CD4(+) T cell, which may serve as an important mechanism of tumor-induced immunosuppression. ..
  3. pmc Prevalence and trends of aminoglycoside resistance in Shigella worldwide, 1999-2010
    Bing Gu
    Department of Laboratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, China National Key Clinical, Department of Laboratory Medicine, Nanjing, Jiangsu 210029, China
    J Biomed Res 27:103-15. 2013
    ..Distribution in Shigella resistance differs sharply based on geographic areas, periods of time and subtypes. The results from the present study highlight the need for continuous surveillance of resistance and control of antibiotic usage...
  4. pmc The study on newly developed McAb NJ001 specific to non-small cell lung cancer and its biological characteristics
    Shiyang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    PLoS ONE 7:e33009. 2012
    ..NJ001 is of great value concerning immunodiagnostics and immunotherapy for NSCLC and holds promise for further research regarding the mechanism underlying tumor progression of NSCLC...
  5. doi Can plasma DNA monitoring be employed in personalized chemotherapy for patients with advanced lung cancer?
    Shiyang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    Biomed Pharmacother 66:131-7. 2012
    ..The quantification of plasma DNA is a sensitive indicator of chemotherapeutic efficacy in advanced lung cancer patients, and it can be useful in predicting response to therapy and guiding medication...
  6. ncbi [Methylation quantification of adenomatous polyposis coli (APC) gene promoter in plasma of lung cancer patients]
    Shi Yang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, PR China
    Ai Zheng 28:384-9. 2009
    ..This study was to develop a real-time quantitative methylation specific PCR (real-time QMSP) method, and detect the methylation of APC gene promoter in plasma of lung cancer patients...
  7. ncbi [Research and development of medical case database: a novel medical case information system integrating with biospecimen management]
    Shiyang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 27:302-6, 319. 2010
    ..It realizes synthesized and dynamic management of medical case and biospecimen, which may be considered as a new management platform...
  8. doi Double recognition of oligonucleotide and protein in the detection of DNA methylation with surface plasmon resonance biosensors
    Shiyang Pan
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
    Biosens Bioelectron 26:850-3. 2010
    ..It will improve our ability to detect DNA methylation specifically and rapidly, and promote our understanding of the role of DNA methylation in gene regulation and diseases...
  9. ncbi [Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines]
    Li Xia Zhang
    Center of Clinical Laboratory, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, P R China
    Ai Zheng 26:576-80. 2007
    ..In previous research, we detected APC promoter methylation in 47% lung tumor tissues. This study was to analyze the effect of APC promoter methylation on the gene transcription in 3 lung cancer cell lines...
  10. ncbi [Quantitative detection of APC/RASSF1A promoter methylation in the plasma of patients with cervical diseases]
    Hong Wang
    Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Fu Chan Ke Za Zhi 48:929-34. 2013
    ....
  11. ncbi [Study of quantitative detection of circulating DNA in the plasma of patients with cervical lesion]
    Hong Wang
    Department of Laboratory Medicine, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Fu Chan Ke Za Zhi 46:501-4. 2011
    ..To quantitatively detect circulating DNA levels in the plasma of patients withcervical lesion and to determine the value for diagnosis of cervical lesion and cervical cancer...
  12. ncbi [Dynamic monitoring of plasma circulating DNA in patients with acute myeloid leukemia and its clinical significance]
    Ye Jiang
    Department of Laboratory Medicine, Nanjing Medical University, Nanjing, Jiangsu Province, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 20:53-6. 2012
    ..3%) relapsed patients, but no increase was found in 22 out of 25 (88.0%) non-relapsed patients. It is concluded that the quantification of plasma DNA may be useful for evaluating therapeutic effects and monitoring relapse in AML patients...
  13. ncbi [The level of peripheral circular DNA in patients with hand foot and mouth disease]
    Zhao xia Zhao
    Department of Laboratory Medicine, Fifth Hospital of Shijiazhuang, Shijiazhuang 050021, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 25:483-5. 2011
    ..To determine the circular DNA level of patients with hand foot and mouth disease (HFMD) and evaluate its potential clinical value...
  14. ncbi [Expression of carbonic anhydrase II in human testes and spermatozoa and its clinical significance]
    Chun Zhao
    Center of Clinical Laboratory, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China
    Zhonghua Nan Ke Xue 16:911-4. 2010
    ..To investigate the expression of carbonic anhydrase II (CA2) in human testes and spermatozoa, and to compare the expressions of CA2 in ejaculated spermatozoa between normozoospermic and asthenozoospermic men...
  15. pmc Plasma Vitamin D Levels And Vitamin D Receptor Polymorphisms Are Associated with Survival of Non-small Cell Lung Cancer
    Yao Liu
    Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 210029, China
    Chin J Cancer Res 23:33-7. 2011
    ..Thus we hypothesized that plasma vitamin D levels and single nucleotide polymorphisms (SNPs) in may be of prognostic significance in non-small cell lung cancer (NSCLC)...
  16. ncbi Polymorphisms in EGFR and VEGF contribute to non-small-cell lung cancer survival in a Chinese population
    Jing Dong
    Department of Epidemiology and Biostatistics, Cancer Center, Nanjing Medical University, 140 Hanzhong Road, Nanjing 210029, China
    Carcinogenesis 31:1080-6. 2010
    ..56, 95% CI = 0.39-0.83). Stepwise COX regression analyses suggested that EGFR rs373506, rs759165 and rs6958497 may be independent candidate biomarkers to predict NSCLC survival in this population...
  17. doi Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis
    Wen Gao
    Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 210029
    Biomed Pharmacother 64:399-408. 2010
    ..MiRNA expression profiles may become useful biomarkers for cancer diagnostics, prognosis and prediction of response to treatment, and it could be a powerful tool for cancer prevention and therapeutics...