Kui rong Jiang
Affiliation: Nanjing Medical University
Liu X, Huang Y, Yuan H, Qi X, Manjunath Y, Avella D, et al
. Disruption of oncogenic liver-intestine cadherin (CDH17) drives apoptotic pancreatic cancer death. Cancer Lett. 2019;454:204-214 pubmed publisher
..Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. ..
Yin J, Lu Z, Wu P, Wu J, Gao W, Wei J, et al
. Afferent Loop Decompression Technique is Associated with a Reduction in Pancreatic Fistula Following Pancreaticoduodenectomy. World J Surg. 2018;42:3726-3735 pubmed publisher
..ALDT may reduce the incidence of POPF after PD. ..
Qian D, Lu Z, Jackson R, Wu J, Liu X, Cai B, et al
. Effect of antecolic or retrocolic route of gastroenteric anastomosis on delayed gastric emptying after pancreaticoduodenectomy: A meta-analysis of randomized controlled trials. Pancreatology. 2016;16:142-50 pubmed publisher
..Results of the meta-analysis reveal that DGE occurrence is not affected by route of gastroenteric anastomosis. Anastomosis approach should be chosen according to the surgeons' preference. ..
Hu H, Wang Y, Ding X, He Y, Lu Z, Wu P, et al
. Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3. Mol Cancer. 2018;17:18 pubmed publisher
..Together, these results indicate that XLOC_000647 functions as a novel tumor suppressor of lncRNA and acts as an important regulator of NLRP3, inhibiting cell proliferation, invasion, and EMT in PC. ..
Zhu Y, Zhang J, Xie K, Tang J, Liang W, Zhu R, et al
. Specific-detection of clinical samples, systematic functional investigations, and transcriptome analysis reveals that splice variant MUC4/Y contributes to the malignant progression of pancreatic cancer by triggering malignancy-related positive feedba. J Transl Med. 2014;12:309 pubmed publisher
..MUC4/Y- expression model is proven to a valuable tool for the further dissection of MUC4-mediated functions and mechanisms. ..
Qian D, Lu Z, Xu Q, Wu P, Tian L, Zhao L, et al
. Galectin-1-driven upregulation of SDF-1 in pancreatic stellate cells promotes pancreatic cancer metastasis. Cancer Lett. 2017;397:43-51 pubmed publisher
..Collectively, the present studies demonstrate that Galectin-1-driven production of SDF-1 in PSCs through activation of NF-ÎºB promotes metastasis in PDAC, offering a potential target in the treatment of pancreatic cancer. ..
Zhang J, Zhu Y, Zhang X, Liu D, Wang Y, Yang C, et al
. Yin Yang-1 suppresses pancreatic ductal adenocarcinoma cell proliferation and tumor growth by regulating SOX2OT-SOX2 axis. Cancer Lett. 2017;408:144-154 pubmed publisher