Yan Liu

Summary

Country: China

Publications

  1. pmc Effects of eleutheroside B and eleutheroside E on activity of cytochrome P450 in rat liver microsomes
    Sixun Guo
    Department of Pharmacy, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China
    BMC Complement Altern Med 14:1. 2014
  2. ncbi request reprint Two new cyanogenic glucosides from the leaves of Hydrangea macrophylla
    Chun Juan Yang
    College of Pharmacy, Harbin Medical University, No 157 Baojian Road, Nangang District, Harbin 150081, China
    Molecules 17:5396-403. 2012
  3. ncbi request reprint [Effect of Qingkailing injection on rat CYP1A2 and CYP2D6 activity]
    Yan Liu
    Institute of Pharmacy and Drug, The Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province University Key Lab, Harbin 150086, China
    Zhongguo Zhong Yao Za Zhi 32:2044-7. 2007
  4. ncbi request reprint Enhanced oral bioavailability of Wurenchun (Fructus Schisandrae Chinensis extracts) by self-emulsifying drug delivery systems
    Bing Shao
    Department of Pharmacy, Key Laboratory of Medications Research, College of Heilongjiang Province, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
    Drug Dev Ind Pharm 36:1356-63. 2010
  5. ncbi request reprint UPLC-MS-MS method for simultaneous determination of caffeine, tolbutamide, metoprolol, and dapsone in rat plasma and its application to cytochrome P450 activity study in rats
    Yan Liu
    Department of Pharmacy, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, China
    J Chromatogr Sci 51:26-32. 2013
  6. ncbi request reprint Effect of sodium ozagrel on the activity of rat CYP2D6
    Hong Wu
    College of Pharmacy, Harbin Medical University, Harbin 150081, PR China Mudanjiang Medical College, Mudanjiang 157011, PR China
    Eur J Pharmacol 573:55-9. 2007
  7. ncbi request reprint RGD-modified endostatin peptide 30 derived from endostatin suppresses invasion and migration of HepG2 cells through the αvβ3 pathway
    Shuyan Li
    Department of Biochemistry and Molecular Biology, Harbin Medical University, No 194 Baojian Road, Harbin, China
    Cancer Biother Radiopharm 26:529-38. 2011
  8. ncbi request reprint Highly sensitive determination of Schisandrin and Schisandrin B in plasma of rats after administration of Wurenchun (Fructus Schisandrae Chinensis Extracts) preparations by LC-ESI-MS/MS
    Jingling Tang
    Department of Pharmaceutics, School of Pharmacy, Harbin Medical University, Harbin, 150086, China
    Biomed Chromatogr 24:675-81. 2010
  9. ncbi request reprint Effects of Panax notoginseng saponins on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats in vivo
    Rui Liu
    Department of Pharmacy, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China
    Phytother Res 26:1113-8. 2012
  10. ncbi request reprint [The role of subtypes of voltage-gated K+ channels in pulmonary vasoconstriction induced by 15-hydroeicosatetraenoic acid]
    Qian Li
    College of Pharmacy, Harbin Medical University, Harbin 150086, China
    Yao Xue Xue Bao 41:412-7. 2006

Collaborators

Detail Information

Publications13

  1. pmc Effects of eleutheroside B and eleutheroside E on activity of cytochrome P450 in rat liver microsomes
    Sixun Guo
    Department of Pharmacy, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China
    BMC Complement Altern Med 14:1. 2014
    ..This study was to investigate the effects of EB and EE on CYP2C9, CYP2D6, CYP2E1 and CYP3A4 in rat liver microsomes in vitro...
  2. ncbi request reprint Two new cyanogenic glucosides from the leaves of Hydrangea macrophylla
    Chun Juan Yang
    College of Pharmacy, Harbin Medical University, No 157 Baojian Road, Nangang District, Harbin 150081, China
    Molecules 17:5396-403. 2012
    ....
  3. ncbi request reprint [Effect of Qingkailing injection on rat CYP1A2 and CYP2D6 activity]
    Yan Liu
    Institute of Pharmacy and Drug, The Second Affiliated Hospital of Harbin Medical University, Heilongjiang Province University Key Lab, Harbin 150086, China
    Zhongguo Zhong Yao Za Zhi 32:2044-7. 2007
    ..The present study investigates the influence of Qingkailing injection on rat liver CYP1A2 and CYP2D6 activity in vivo and in vitro, respectively...
  4. ncbi request reprint Enhanced oral bioavailability of Wurenchun (Fructus Schisandrae Chinensis extracts) by self-emulsifying drug delivery systems
    Bing Shao
    Department of Pharmacy, Key Laboratory of Medications Research, College of Heilongjiang Province, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
    Drug Dev Ind Pharm 36:1356-63. 2010
    ..The main purpose of this work is to prepare self-emulsifying drug delivery systems (SEDDS) for enhancing the solubility, dissolution rate, and oral bioavailability of poorly water-soluble traditional Chinese medicines, Wurenchun...
  5. ncbi request reprint UPLC-MS-MS method for simultaneous determination of caffeine, tolbutamide, metoprolol, and dapsone in rat plasma and its application to cytochrome P450 activity study in rats
    Yan Liu
    Department of Pharmacy, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, China
    J Chromatogr Sci 51:26-32. 2013
    ..The method was successfully applied to pharmacokinetic studies of the four probe drugs of the four CYP450 isoforms and used to evaluate the effects of breviscapine on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats...
  6. ncbi request reprint Effect of sodium ozagrel on the activity of rat CYP2D6
    Hong Wu
    College of Pharmacy, Harbin Medical University, Harbin 150081, PR China Mudanjiang Medical College, Mudanjiang 157011, PR China
    Eur J Pharmacol 573:55-9. 2007
    ..In conclusion, sodium ozagrel metabolism in rats is mediated primarily through CYP2D6, and sodium ozagrel can induce CYP2D6 activity...
  7. ncbi request reprint RGD-modified endostatin peptide 30 derived from endostatin suppresses invasion and migration of HepG2 cells through the αvβ3 pathway
    Shuyan Li
    Department of Biochemistry and Molecular Biology, Harbin Medical University, No 194 Baojian Road, Harbin, China
    Cancer Biother Radiopharm 26:529-38. 2011
    ..Lastly, an antibody against αvβ3 enhanced the biological effects of peptide 30...
  8. ncbi request reprint Highly sensitive determination of Schisandrin and Schisandrin B in plasma of rats after administration of Wurenchun (Fructus Schisandrae Chinensis Extracts) preparations by LC-ESI-MS/MS
    Jingling Tang
    Department of Pharmaceutics, School of Pharmacy, Harbin Medical University, Harbin, 150086, China
    Biomed Chromatogr 24:675-81. 2010
    ..5 and 107.2%. Finally, the LC-ESI-MS/MS method was successfully applied to study the pharmacokinetics of Schisandrin and Schisandrin B in rats after administration of Wurenchun commercial formulations to rats...
  9. ncbi request reprint Effects of Panax notoginseng saponins on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats in vivo
    Rui Liu
    Department of Pharmacy, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China
    Phytother Res 26:1113-8. 2012
    ..In conclusion, the results indicate that PNS could induce CYP1A2, which may affect the disposition of medicines primarily dependent on the CYP1A2 pathway. Our work may be the basis of related herb-drug interactions in the clinic...
  10. ncbi request reprint [The role of subtypes of voltage-gated K+ channels in pulmonary vasoconstriction induced by 15-hydroeicosatetraenoic acid]
    Qian Li
    College of Pharmacy, Harbin Medical University, Harbin 150086, China
    Yao Xue Xue Bao 41:412-7. 2006
    ..To observe the effect of subtypes of Kv channels in rat pulmonary artery smooth muscle cells (PASMCs) on the process of pulmonary vasoconstriction induced by 15-HETE...
  11. pmc Activation of cardiac muscarinic M3 receptors induces delayed cardioprotection by preserving phosphorylated connexin43 and up-regulating cyclooxygenase-2 expression
    Jinlong Zhao
    Institute of Clinical Pharmacy, Second Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China
    Br J Pharmacol 159:1217-25. 2010
    ..Consequently, the present study was undertaken to investigate whether stimulation of M(3)-mAChRs can induce delayed preconditioning in rats, and to characterize the potential mechanism...
  12. ncbi request reprint Mitochondria-mediated tumstatin peptide-induced HepG2 cell apoptosis
    Yan Liu
    Department of Biochemistry and Molecular Biology, Harbin Medical University, The Key Laboratory of Biomedical Engineering of Heilongjiang Province, Harbin 150081, PR China
    Int J Mol Med 24:653-9. 2009
    ..Peptide 19 decreased the mitochondrial membrane potential and induced the release of cytochrome C from mitochondria to the cytoplasm. In conclusion, peptide 19 induced HepG2 cell apoptosis through the mitochondrial apoptosis pathway...
  13. ncbi request reprint Determination of mangiferin in rat eyes and pharmacokinetic study in plasma after oral administration of mangiferin-hydroxypropyl-beta-cyclodextrin inclusion
    Hong Zhang
    Eye Hospital, The First Affiliated Hospital, Harbin Medical University, Harbin, China
    J Ocul Pharmacol Ther 26:319-24. 2010
    ..To determine whether mangiferin can enter the eye, because the eye possesses the unique blood-ocular barrier...