Shiguo Liu

Summary

Country: China

Publications

  1. doi request reprint Association study between MAO-A gene promoter VNTR polymorphisms and obsessive-compulsive disorder
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China
    J Anxiety Disord 27:435-7. 2013
  2. pmc Lack of association of -607 C/A and -137 G/C polymorphisms in interleukin 18 gene with susceptibility to gout disease in Chinese Han male population
    Changgui Li
    Gout Laboratory, Medical School Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, 266003, China
    Rheumatol Int 32:1805-7. 2012
  3. pmc Polymorphisms in the presumptive promoter region of the SLC2A9 gene are associated with gout in a Chinese male population
    Changgui Li
    the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China
    PLoS ONE 7:e24561. 2012
  4. doi request reprint Genetic association of polymorphism rs1333049 with gout
    Binbin Wang
    Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Common Diseases Gout Laboratory, Affiliated Hospital of Medical College, Qingdao University, Qingdao, Shandong, China
    Rheumatology (Oxford) 50:1559-61. 2011
  5. doi request reprint No significant association between Catechol-O-methyl transferase (COMT) -287A/G gene polymorphism and Tourette's syndrome in family-based association study in Chinese Han population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, China
    Eur Child Adolesc Psychiatry 20:593-6. 2011
  6. doi request reprint Lack of an association between obsessive-compulsive disorder and polymorphisms in the 3' untranslated region of GRIN2B in a Chinese Han population
    Shiguo Liu
    the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China
    Psychiatry Res 196:142-4. 2012
  7. doi request reprint Polymorphisms -1082 G/A and -819 C/T in the interleukin-10 gene are not associated with gout susceptibility in the Chinese Han male population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China
    Genet Test Mol Biomarkers 16:879-83. 2012
  8. ncbi request reprint A case-control association study between Obsessive-Compulsive Disorder (OCD) and the MCP-1 -2518G/A polymorphism in a Chinese sample
    Xinhua Zhang
    Department of Pychology and Psychiatry, Medical College, Qingdao University, Qingdao, China
    Rev Bras Psiquiatr 34:451-3. 2012
  9. doi request reprint Lack of association between polymorphism -592A/C in the promoter region of the IL10 gene and Tourette's syndrome in a family-based association study in the Chinese Han population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China
    Genet Test Mol Biomarkers 15:733-5. 2011
  10. doi request reprint Association of catechol-O-methyl transferase (COMT) gene -287A/G polymorphism with susceptibility to obsessive-compulsive disorder in Chinese Han population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, China
    Am J Med Genet B Neuropsychiatr Genet 156:393-400. 2011

Collaborators

Detail Information

Publications19

  1. doi request reprint Association study between MAO-A gene promoter VNTR polymorphisms and obsessive-compulsive disorder
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China
    J Anxiety Disord 27:435-7. 2013
    ..Given that this is the first investigation of this gene in OCD in a Chinese Han population, further studies are required to obtain more definitive conclusions in a larger number of subjects...
  2. pmc Lack of association of -607 C/A and -137 G/C polymorphisms in interleukin 18 gene with susceptibility to gout disease in Chinese Han male population
    Changgui Li
    Gout Laboratory, Medical School Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, 266003, China
    Rheumatol Int 32:1805-7. 2012
    ..Our study might suggest that -607 C/A and -137 G/C polymorphisms in the promoter of IL18 are not associated with susceptibility to gout and thus do not play a major role in the development of gout in the Chinese Han male population...
  3. pmc Polymorphisms in the presumptive promoter region of the SLC2A9 gene are associated with gout in a Chinese male population
    Changgui Li
    the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China
    PLoS ONE 7:e24561. 2012
    ..We therefore investigated associations between gout and polymorphisms and haplotypes in the presumptive promoter region of GLUT9 in Chinese males...
  4. doi request reprint Genetic association of polymorphism rs1333049 with gout
    Binbin Wang
    Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Common Diseases Gout Laboratory, Affiliated Hospital of Medical College, Qingdao University, Qingdao, Shandong, China
    Rheumatology (Oxford) 50:1559-61. 2011
    ..The single nucleotide polymorphism (SNP) rs1333049 (C/G) on chromosome 9p21 has been implicated in previous studies to be associated with CAD. The aim of this study was to evaluate the relationship between this SNP and gout pathogenesis...
  5. doi request reprint No significant association between Catechol-O-methyl transferase (COMT) -287A/G gene polymorphism and Tourette's syndrome in family-based association study in Chinese Han population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, China
    Eur Child Adolesc Psychiatry 20:593-6. 2011
    ..Our results also suggested that there may be a lack of association between the TS and -287A/G polymorphism of COMT in Chinese Han population...
  6. doi request reprint Lack of an association between obsessive-compulsive disorder and polymorphisms in the 3' untranslated region of GRIN2B in a Chinese Han population
    Shiguo Liu
    the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China
    Psychiatry Res 196:142-4. 2012
    ..Our results suggest the lack of an association between OCD and polymorphisms in the 3'-UTR of GRIN2B in a Chinese Han population...
  7. doi request reprint Polymorphisms -1082 G/A and -819 C/T in the interleukin-10 gene are not associated with gout susceptibility in the Chinese Han male population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China
    Genet Test Mol Biomarkers 16:879-83. 2012
    ..Interleukin 10 (IL-10) is an important immunoregulatory cytokine, levels of which can be influenced by functional single-nucleotide polymorphisms in the promoter...
  8. ncbi request reprint A case-control association study between Obsessive-Compulsive Disorder (OCD) and the MCP-1 -2518G/A polymorphism in a Chinese sample
    Xinhua Zhang
    Department of Pychology and Psychiatry, Medical College, Qingdao University, Qingdao, China
    Rev Bras Psiquiatr 34:451-3. 2012
    ..To investigate the association between Obsessive-Compulsive Disorder (OCD) and a functional polymorphism of MCP-1 in the Chinese Han population...
  9. doi request reprint Lack of association between polymorphism -592A/C in the promoter region of the IL10 gene and Tourette's syndrome in a family-based association study in the Chinese Han population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China
    Genet Test Mol Biomarkers 15:733-5. 2011
    ..These results suggested that IL10 may not play a major role in the development of TS in the Chinese Han population...
  10. doi request reprint Association of catechol-O-methyl transferase (COMT) gene -287A/G polymorphism with susceptibility to obsessive-compulsive disorder in Chinese Han population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, China
    Am J Med Genet B Neuropsychiatr Genet 156:393-400. 2011
    ..Our study supports the involvement of the COMT -287A/G polymorphism in the genetic susceptibility to OCD in Chinese Han population...
  11. doi request reprint Genotypes and phenotypes of congenital goitre and hypothyroidism caused by mutations in dual oxidase 2 genes
    Fang Wang
    Department of Endocrinology, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, China
    Clin Endocrinol (Oxf) 81:452-7. 2014
    ..The aim of this study was to screen for DUOX2, TPO and TG mutations in Chinese patients with congenital hypothyroidism (CH) and goitre and to define the relationships between DUOX2 genotypes and clinical phenotypes...
  12. doi request reprint The rs7517847 polymorphism in the IL-23R gene is associated with gout in a Chinese Han male population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, P R China
    Mod Rheumatol 25:449-52. 2015
    ..This study aimed to determine whether the IL-23R rs7517847 (G/T) polymorphism is associated with gout in a Chinese Han male population...
  13. doi request reprint Association of IL8 -251A/T, IL12B -1188A/C and TNF-α -238A/G polymorphisms with Tourette syndrome in a family-based association study in a Chinese Han population
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China
    Neurosci Lett 495:155-8. 2011
    ..However, these results need to be replicated using larger datasets collected from different populations...
  14. doi request reprint Family-based association study between monoamine oxidase A (MAOA) gene promoter VNTR polymorphism and Tourette's syndrome in Chinese Han population
    Shiguo Liu
    a Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China
    Neurocase 21:106-8. 2015
    ..515, df = 1, p > 0.05). The negative result may be mainly due to the small sample size, but we don't deny the role of gene coding serotonergic or monoaminergic structures in the etiology of TS. ..
  15. doi request reprint Positive correlation between Beta-3-Adrenergic Receptor (ADRB3) gene and gout in a Chinese male population
    Binbin Wang
    Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Common Diseases Gout Laboratory, The Affiliated Hospital of the Medical College, Qingdao University, Qingdao, Shandong, China
    J Rheumatol 38:738-40. 2011
    ..As gout is characterized by elevated serum concentrations of uric acid, we investigated ADRB3 as a potential candidate for gout...
  16. doi request reprint Clinical and genetic analysis of a compound heterozygous mutation in the thyroglobulin gene in a Chinese twin family with congenital goiter and hypothyroidism
    Shiguo Liu
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, China
    Twin Res Hum Genet 15:126-32. 2012
    ....
  17. doi request reprint The CC chemokine ligand 2 (CCL2) polymorphism -2518A/G is associated with gout in the Chinese Han male population
    Ruixia Sun
    Shandong Provincial Key Laboratory of Metabolic Disease, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, 266003, China
    Rheumatol Int 35:479-84. 2015
    ..Our findings support a key role for the CCL2 SNP -2518A/G in association with gout susceptibility in the Chinese Han male population. However, additional studies in other populations should be carried out to confirm this finding...
  18. doi request reprint A novel missense mutation (I26M) in DUOXA2 causing congenital goiter hypothyroidism impairs NADPH oxidase activity but not protein expression
    Shiguo Liu
    Prenatal Diagnosis Center S L, Genetic Laboratory S L, and Departments of Endocrinology L L, S Y and Ultrasonography X N, The Affiliated Hospital of Qingdao University, Qingdao 266003, China Department of Clinical Laboratory D L, Linyi People s Hospital, Shandong University, Linyi 276003, China Graduate School H X, Peking Union Medical College, Beijing 100730, China and World Health Organization Collaborating Centre for Research in Human Reproduction H X, and National Research Institute for Family Planning H X, Beijing 100081, China
    J Clin Endocrinol Metab 100:1225-9. 2015
    ..Genetic defects in DUOXA2 lead to an impairment of the H2O2-generating system, in turn causing congenital hypothyroidism (CH) with goiter...
  19. pmc Genetic variations in IL1A and IL1RN are associated with the risk of preeclampsia in Chinese Han population
    Jing Li
    1 Department of Clinical Laboratory, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, 266003, China 2
    Sci Rep 4:5250. 2014
    ..24, 95%CI 0.15-0.40). For rs17561, the C allele was the risk factor for predisposition to PE (P = 0.012, OR = 1.496, 95%CI 1.089-2.055). Our results suggest IL1RN and IL1A may involve in the development of PE in Chinese Han population. ..