Research Topics
Species | Lingbo LiuSummaryCountry: China Publications
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Detail Information
Publications
[Depressing the immune escape of acute myelomonocytic leukemia via an anti-Fas ribozyme]Ling Bo Liu
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:862-6. 2006....
hMRE11 plays an important role in U937 cellular response to DNA double-strand breaks following etoposideLing Bo Liu
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:10-5. 2007..95 +/- 2.91% (P < 0.05). It is concluded that the nuclear focus formation of hMRE11 protein may be a response to DNA damage induced by topoisomerase II inhibitor VP-16 in human promonocytic cell line U937...
Comparison of immunophenotype and clinical manifestations between patients with M5a and M5b of acute monocytic leukemiaLing Bo Liu
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:1079-82. 2006..It seems that the complete remission rate and disease-free survival of patients with M(5a) and M(5b) are not different from that of currently available therapy...
Attenuation of GVHD for allo-bone marrow transplantation recipient by FasL-Fas pathway in an H-2 haplotype disparate mouse combinationLingbo Liu
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
J Huazhong Univ Sci Technolog Med Sci 24:329-33. 2004..01). It is suggested that the attenuation of GVHD in allo-BMT recipient could be successfully achieved through FasL-Fas pathway in an H-2 haplotype disparate mouse combination...
Cytobiological and clinicobiological features of AML with 11q23 chromosome abnormalitiesLing Bo Liu
Institute of Hematology, Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 13:932-6. 2005..001). It is concluded that the category AML with 11q23 abnormalities accounts for 6.19% of all the newly diagnosed AML cases, that seems to be closely associated with monocytic differentiation blocking with a dismal prognosis...
[Expression of immune response molecules and function of fas ligand on surface of AML WEHI-3 cells]Ling Bo Liu
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:535-8. 2006..5)%, (35 +/- 3.2)% and (43 +/- 2.7)% (n = 5) respectively. It is concluded that WEHI-3 cells have high expression of FasL and low expression of Fas and CD80 on their cell membrane, and can induce the apoptosis of Fas(+) YAC-1 cells...
Comparison of cytogenetics and clinical manifestations between M5a and M5b of acute monocytic leukemiaLing Bo Liu
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:654-7. 2006....
[Selected elimination of mouse alloreactive T cells by Fas-FasL passway]Lingbo Liu
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Zhonghua Xue Ye Xue Za Zhi 23:187-90. 2002..01). CONCLUSION: The higher exogenous mFasL-expressing mouse EHCs can deplete ARTC against their own major histocompatibility complex (MHC) antigens in vitro...
Selective depletion of the allo-antigen specific T cells by Fas/FasL pathway by cytokine IFN-gamma and IL-2Juan Xiao
The Institute of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022
J Huazhong Univ Sci Technolog Med Sci 23:344-7. 2003....
Apoptosis of leukemia cells induced by CD34+ cells transferred exogenous Fas ligandJuan Xiao
Institute of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022
J Huazhong Univ Sci Technolog Med Sci 22:197-9. 2002....
CD34+ cells from patients with myelodysplastic syndrome present different p21 dependent premature senescenceYin Xiao
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Leuk Res 37:333-40. 2013....
Cloning and expression of the cDNA of a murine soluble FasZhongbo Hu
Institute of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022
J Huazhong Univ Sci Technolog Med Sci 22:186-9, 196. 2002..Apoptosis inducing test showed that the expression of this murine Fas C could block the Fas-induced apoptosis, which confirmed the biological activity of the recombinant Fas C...
Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cellsJing Zou
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Ann Hematol 91:813-23. 2012..However, p38 inhibition had no significant effect on HSC differentiation and proliferation. These findings suggest that inhibition of p38 activation may represent a novel strategy to promote ex vivo expansion of hUCB HSCs...
Lower phosphorylation of p38 MAPK blocks the oxidative stress-induced senescence in myeloid leukemic CD34(+)CD38 (-) cellsYin Xiao
Department of Hematology, Huazhong University of Science and Technology, Wuhan, China
J Huazhong Univ Sci Technolog Med Sci 32:328-33. 2012..These findings suggested that, although excessive accumulation of oxidative DNA damage was present in LSCs, the relatively decreased phosphorylation of p38 might help leukemic cells escape senescence and apoptosis...
The cross-talk between ROS and p38MAPKα in the Ex Vivo expanded human umbilical cord blood CD133(+) cellsJing Zou
Department of Hematology, Huazhong University of Science and Technology, Wuhan, China
J Huazhong Univ Sci Technolog Med Sci 31:591-5. 2011....
Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKα dependent mannerYi Luo
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Exp Gerontol 46:860-7. 2011..Instead, the induction of autophagy by H2O2 depends on the induction of intracellular production of reactive oxygen species (ROS) and activation of the p38 mitogen-activated protein kinase α (p38 MAPKα) pathway...
