Lingbo Liu

Summary

Country: China

Publications

  1. ncbi request reprint [Depressing the immune escape of acute myelomonocytic leukemia via an anti-Fas ribozyme]
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:862-6. 2006
  2. ncbi request reprint hMRE11 plays an important role in U937 cellular response to DNA double-strand breaks following etoposide
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:10-5. 2007
  3. ncbi request reprint Comparison of immunophenotype and clinical manifestations between patients with M5a and M5b of acute monocytic leukemia
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:1079-82. 2006
  4. ncbi request reprint Attenuation of GVHD for allo-bone marrow transplantation recipient by FasL-Fas pathway in an H-2 haplotype disparate mouse combination
    Lingbo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    J Huazhong Univ Sci Technolog Med Sci 24:329-33. 2004
  5. ncbi request reprint Cytobiological and clinicobiological features of AML with 11q23 chromosome abnormalities
    Ling Bo Liu
    Institute of Hematology, Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 13:932-6. 2005
  6. ncbi request reprint [Expression of immune response molecules and function of fas ligand on surface of AML WEHI-3 cells]
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:535-8. 2006
  7. ncbi request reprint Comparison of cytogenetics and clinical manifestations between M5a and M5b of acute monocytic leukemia
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:654-7. 2006
  8. pmc Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells
    Jing Zou
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Ann Hematol 91:813-23. 2012
  9. ncbi request reprint [Selected elimination of mouse alloreactive T cells by Fas-FasL passway]
    Lingbo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhonghua Xue Ye Xue Za Zhi 23:187-90. 2002
  10. ncbi request reprint Selective depletion of the allo-antigen specific T cells by Fas/FasL pathway by cytokine IFN-gamma and IL-2
    Juan Xiao
    The Institute of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022
    J Huazhong Univ Sci Technolog Med Sci 23:344-7. 2003

Detail Information

Publications17

  1. ncbi request reprint [Depressing the immune escape of acute myelomonocytic leukemia via an anti-Fas ribozyme]
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:862-6. 2006
    ....
  2. ncbi request reprint hMRE11 plays an important role in U937 cellular response to DNA double-strand breaks following etoposide
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:10-5. 2007
    ..95 +/- 2.91% (P < 0.05). It is concluded that the nuclear focus formation of hMRE11 protein may be a response to DNA damage induced by topoisomerase II inhibitor VP-16 in human promonocytic cell line U937...
  3. ncbi request reprint Comparison of immunophenotype and clinical manifestations between patients with M5a and M5b of acute monocytic leukemia
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:1079-82. 2006
    ..It seems that the complete remission rate and disease-free survival of patients with M(5a) and M(5b) are not different from that of currently available therapy...
  4. ncbi request reprint Attenuation of GVHD for allo-bone marrow transplantation recipient by FasL-Fas pathway in an H-2 haplotype disparate mouse combination
    Lingbo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    J Huazhong Univ Sci Technolog Med Sci 24:329-33. 2004
    ..01). It is suggested that the attenuation of GVHD in allo-BMT recipient could be successfully achieved through FasL-Fas pathway in an H-2 haplotype disparate mouse combination...
  5. ncbi request reprint Cytobiological and clinicobiological features of AML with 11q23 chromosome abnormalities
    Ling Bo Liu
    Institute of Hematology, Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 13:932-6. 2005
    ..001). It is concluded that the category AML with 11q23 abnormalities accounts for 6.19% of all the newly diagnosed AML cases, that seems to be closely associated with monocytic differentiation blocking with a dismal prognosis...
  6. ncbi request reprint [Expression of immune response molecules and function of fas ligand on surface of AML WEHI-3 cells]
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:535-8. 2006
    ..5)%, (35 +/- 3.2)% and (43 +/- 2.7)% (n = 5) respectively. It is concluded that WEHI-3 cells have high expression of FasL and low expression of Fas and CD80 on their cell membrane, and can induce the apoptosis of Fas(+) YAC-1 cells...
  7. ncbi request reprint Comparison of cytogenetics and clinical manifestations between M5a and M5b of acute monocytic leukemia
    Ling Bo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:654-7. 2006
    ....
  8. pmc Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells
    Jing Zou
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Ann Hematol 91:813-23. 2012
    ..However, p38 inhibition had no significant effect on HSC differentiation and proliferation. These findings suggest that inhibition of p38 activation may represent a novel strategy to promote ex vivo expansion of hUCB HSCs...
  9. ncbi request reprint [Selected elimination of mouse alloreactive T cells by Fas-FasL passway]
    Lingbo Liu
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhonghua Xue Ye Xue Za Zhi 23:187-90. 2002
    ..To explore a new method of alleviating graft-versus-host disease (GVHD) after allogeneic bone marrow transplantation (allo-BMT) through selected elimination of mouse alloreactive T cells (ARTC) by Fas-Fas ligand (FasL) passway...
  10. ncbi request reprint Selective depletion of the allo-antigen specific T cells by Fas/FasL pathway by cytokine IFN-gamma and IL-2
    Juan Xiao
    The Institute of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022
    J Huazhong Univ Sci Technolog Med Sci 23:344-7. 2003
    ....
  11. pmc Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence
    Yi Luo
    1 Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China 2 Division of Radiation Health, Department of Pharmaceutical Sciences and Winthrop P Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR 3 Institute of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China 4 Address correspondence to Lingbo Liu, M D, Ph D, Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China and Daohong Zhou, M D, Division of Radiation Health, Department of Pharmaceutical Sciences and Winthrop P Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 West Markham, 607, Little Rock, AR 72205
    Transplantation 97:20-9. 2014
    ..Inhibition of mTOR with rapamycin has the potential to promote long-term hematopoiesis of ex vivo expanded HSCs to facilitate the clinical application of HSC transplantation for various hematologic diseases...
  12. ncbi request reprint Apoptosis of leukemia cells induced by CD34+ cells transferred exogenous Fas ligand
    Juan Xiao
    Institute of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022
    J Huazhong Univ Sci Technolog Med Sci 22:197-9. 2002
    ....
  13. doi request reprint CD34+ cells from patients with myelodysplastic syndrome present different p21 dependent premature senescence
    Yin Xiao
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Leuk Res 37:333-40. 2013
    ....
  14. ncbi request reprint Cloning and expression of the cDNA of a murine soluble Fas
    Zhongbo Hu
    Institute of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022
    J Huazhong Univ Sci Technolog Med Sci 22:186-9, 196. 2002
    ..Apoptosis inducing test showed that the expression of this murine Fas C could block the Fas-induced apoptosis, which confirmed the biological activity of the recombinant Fas C...
  15. doi request reprint The cross-talk between ROS and p38MAPKα in the Ex Vivo expanded human umbilical cord blood CD133(+) cells
    Jing Zou
    Department of Hematology, Huazhong University of Science and Technology, Wuhan, China
    J Huazhong Univ Sci Technolog Med Sci 31:591-5. 2011
    ....
  16. doi request reprint Lower phosphorylation of p38 MAPK blocks the oxidative stress-induced senescence in myeloid leukemic CD34(+)CD38 (-) cells
    Yin Xiao
    Department of Hematology, Huazhong University of Science and Technology, Wuhan, China
    J Huazhong Univ Sci Technolog Med Sci 32:328-33. 2012
    ..These findings suggested that, although excessive accumulation of oxidative DNA damage was present in LSCs, the relatively decreased phosphorylation of p38 might help leukemic cells escape senescence and apoptosis...
  17. pmc Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKα dependent manner
    Yi Luo
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Exp Gerontol 46:860-7. 2011
    ..Instead, the induction of autophagy by H2O2 depends on the induction of intracellular production of reactive oxygen species (ROS) and activation of the p38 mitogen-activated protein kinase α (p38 MAPKα) pathway...