Deng T, Yan G, Song X, Xie L, Zhou Y, Li J, et al
. Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses. Proc Natl Acad Sci U S A. 2018;115:4678-4683 pubmed publisher
..These findings reveal an important mechanism by which p21 can be stabilized by direct deubiquitylation, and they pinpoint a crucial role of the USP11-p21 axis in regulating cell-cycle progression and DNA damage responses. ..
Roy M, Liang L, Xiao X, Feng P, Ye M, Liu J. Lycorine: A prospective natural lead for anticancer drug discovery. Biomed Pharmacother. 2018;107:615-624 pubmed publisher
Zhang H, Wang Z, Xie L, Zhang Y, Deng T, Li J, et al
. Molecular Recognition and In-Vitro-Targeted Inhibition of Renal Cell Carcinoma Using a DNA Aptamer. Mol Ther Nucleic Acids. 2018;12:758-768 pubmed publisher
..Taken together, these results indicate that SW-4b is a potential candidate for development into a novel tool for diagnosis and targeted therapy of RCC. ..
Zhou W, Zhang Y, Zeng Y, Peng M, Li H, Sun S, et al
. Screening and characterization of an Annexin A2 binding aptamer that inhibits the proliferation of myeloma cells. Biochimie. 2018;151:150-158 pubmed publisher
..Furthermore, aptamer wh6 can block MM cell adhesion to ANXA2 and block the proliferation of MM cells induced by ANXA2. In summary, wh6 can be considered a promising candidate tool for MM diagnosis and treatment. ..