Feng Liang

Summary

Country: China

Publications

  1. ncbi Comparison of visible and near-infrared wavelength-excitable fluorescent dyes for molecular imaging of cancer
    Kristen E Adams
    Baylor College of Medicine, Department of Radiology, One Baylor Plaza, MS 360, Houston, Texas 77030, USA
    J Biomed Opt 12:024017. 2007
  2. ncbi A review on biomedical applications of single-walled carbon nanotubes
    Feng Liang
    College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, P R China
    Curr Med Chem 17:10-24. 2010
  3. ncbi Copper complex of hydroxyl-substituted triazamacrocyclic ligand and its antitumor activity
    Feng Liang
    Department of Chemistry, Wuhan University, Wuhan 430072, PR China
    Bioorg Med Chem Lett 13:2469-72. 2003
  4. ncbi Nickel(II) and cobalt(II) complexes of hydroxyl-substituted triazamacrocyclic ligand as potential antitumor agents
    Feng Liang
    Department of Chemistry, Wuhan University, Wuhan 430072, Peoples Republic of China
    Bioorg Med Chem Lett 14:1901-4. 2004
  5. ncbi HeLa cells apoptosis induced by 1,7-dimethyl-1,4,7,10-tetraazacyclododecane
    Li Yang
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072, PR China
    Bioorg Med Chem Lett 17:1818-22. 2007
  6. ncbi Medical applications of macrocyclic polyamines
    Feng Liang
    College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, PR China, 430072
    Curr Med Chem 13:711-27. 2006
  7. ncbi Transcription-inhibition and antitumor activities of N-alkylated tetraazacyclododecanes
    Xiao Qin Xiong
    College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, PR China
    Chem Biodivers 4:2791-7. 2007
  8. ncbi Quaternary ammonium zinc phthalocyanine: inhibiting telomerase by stabilizing G quadruplexes and inducing G-quadruplex structure transition and formation
    Lige Ren
    College of Chemistry and Molecular Sciences, Wuhan University, Hongshan, Luo Jia Shan, Hubei, Wuhan 430072, P R China
    Chembiochem 8:775-80. 2007
  9. ncbi Dicationic pyridium porphyrins appending different peripheral substituents: synthesis and studies for their interactions with DNA
    Song Wu
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072, PR China
    Bioorg Med Chem 14:2956-65. 2006
  10. ncbi Combination of porphyrins and DNA-alkylation agents: synthesis and tumor cell apoptosis induction
    Hanping He
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei, PR China
    Bioorg Med Chem 14:1068-77. 2006

Collaborators

  • Xiang Zhou
  • Li Yang
  • Bo Chen
  • Zheng Li
  • Tao Li
  • Tao Jia
  • Min Liu
  • Yan Zhou
  • Yang Lu
  • Ping Wang
  • Z Tan
  • Jing Huang
  • Xiao Qin Xiong
  • Lige Ren
  • Xiaoping Cao
  • Lijie Cui
  • Zeper Abliz
  • Volkan Seyrantepe
  • Cong Yi Zheng
  • Kristen E Adams
  • Xinfeng Shi
  • Xiao Ping Cao
  • W Edward Billups
  • Hanping He
  • Yang Song
  • Christie M Sayes
  • Shu Hui Wan
  • Song Wu
  • Juanjuan Wu
  • Eva M Sevick-Muraca
  • Jin Ping Qiao
  • Eddy Kuwana
  • Min Xia
  • Yongzhen Liu
  • Liyan Zhao
  • Stephanie Durand
  • Carlos R Morales
  • Aurore Caqueret
  • Maryssa Canuel
  • Roy A Gravel
  • Jacques Michaud
  • Claudia Zwingmann
  • Karine Landry
  • Thierry Levade
  • Jibin Zeng
  • Sergio Marchesini
  • Stephane Carpentier
  • Alexey V Pshezhetsky
  • Antonios G Mikos
  • Shi Ke
  • Lon J Wilson
  • Michael A Barry
  • Karen Hirschi
  • Zhen Fan
  • Balaji Sitharaman
  • Anming Zhang
  • Xiao lin Wang
  • Lixia Zhang
  • Katherine Wu
  • Xiaocheng Weng
  • Sunkuk Kwon
  • Quynh P Pham
  • Michel E Mawad
  • Kevin D Ausman
  • Wenhua Guo
  • Joe Mendez
  • Xiao Jun Wu
  • Xiao Lian Zhang
  • Jennifer L West
  • Linhong Weng
  • Dongqing Li
  • Valerie C Moore
  • Jared L Hudson
  • Xiaolian Zhang
  • Vicki L Colvin
  • Cheng Tai Wu
  • Jonathan M Beach
  • Condell D Doyle
  • Song Gao
  • Yongchun Yang
  • Yan Chang
  • Feng Ming Chu
  • Shishan Yu
  • Wenyi He
  • Jiangong Shi
  • Pei ling Hou
  • Yun Xiang
  • Zong ru Guo

Detail Information

Publications23

  1. ncbi Comparison of visible and near-infrared wavelength-excitable fluorescent dyes for molecular imaging of cancer
    Kristen E Adams
    Baylor College of Medicine, Department of Radiology, One Baylor Plaza, MS 360, Houston, Texas 77030, USA
    J Biomed Opt 12:024017. 2007
    ..5. Immunohistochemistry shows that EGF causes activation of the EGFr signaling pathway, suggesting that prior to use as a targeting, diagnostic agent, potential deleterious effects should be considered...
  2. ncbi A review on biomedical applications of single-walled carbon nanotubes
    Feng Liang
    College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, P R China
    Curr Med Chem 17:10-24. 2010
    ..This manuscript will highlight the recent employment of SWNTs in the field of nanomedicine and bioimaging, and also outline the challenges and future opportunities for biomedical applications of SWNTs...
  3. ncbi Copper complex of hydroxyl-substituted triazamacrocyclic ligand and its antitumor activity
    Feng Liang
    Department of Chemistry, Wuhan University, Wuhan 430072, PR China
    Bioorg Med Chem Lett 13:2469-72. 2003
    ..Also it exhibited perturbation effects to BEL-7402 cell lines cycle and further studies showed that it could cleave supercoiled DNA (pBR 322) to nicked and linear DNA...
  4. ncbi Nickel(II) and cobalt(II) complexes of hydroxyl-substituted triazamacrocyclic ligand as potential antitumor agents
    Feng Liang
    Department of Chemistry, Wuhan University, Wuhan 430072, Peoples Republic of China
    Bioorg Med Chem Lett 14:1901-4. 2004
    ....
  5. ncbi HeLa cells apoptosis induced by 1,7-dimethyl-1,4,7,10-tetraazacyclododecane
    Li Yang
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072, PR China
    Bioorg Med Chem Lett 17:1818-22. 2007
    ..The HeLa cells apoptosis induced by DMC was examined by flow cytometric meter, and further confirmed by observing the morphological changes and DNA fragmentation. No observation of A549 cells induced apoptosis was observed by DMC...
  6. ncbi Medical applications of macrocyclic polyamines
    Feng Liang
    College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, PR China, 430072
    Curr Med Chem 13:711-27. 2006
    ..The current rational design, and medical applications of macrocyclic polyamines will be reviewed in this manuscript...
  7. ncbi Transcription-inhibition and antitumor activities of N-alkylated tetraazacyclododecanes
    Xiao Qin Xiong
    College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, PR China
    Chem Biodivers 4:2791-7. 2007
    ..Three compounds, 5-7, were found to exhibit significant biological activities, with IC50 values towards HeLa cells in the low-micromolar range...
  8. ncbi Quaternary ammonium zinc phthalocyanine: inhibiting telomerase by stabilizing G quadruplexes and inducing G-quadruplex structure transition and formation
    Lige Ren
    College of Chemistry and Molecular Sciences, Wuhan University, Hongshan, Luo Jia Shan, Hubei, Wuhan 430072, P R China
    Chembiochem 8:775-80. 2007
    ..More importantly, ZnPc was found to induce parallel structure formation in cation-deficient conditions. The stability of the induced structure was determined with CD melting assays...
  9. ncbi Dicationic pyridium porphyrins appending different peripheral substituents: synthesis and studies for their interactions with DNA
    Song Wu
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072, PR China
    Bioorg Med Chem 14:2956-65. 2006
    ..We found that both the position of positive charges and steric hindrance could greatly influence their binding affinities and modes to DNA, and then affect their photocleaving abilities to DNA...
  10. ncbi Combination of porphyrins and DNA-alkylation agents: synthesis and tumor cell apoptosis induction
    Hanping He
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei, PR China
    Bioorg Med Chem 14:1068-77. 2006
    ....
  11. ncbi Synthesis and biological studies of N-alkylated cyclic diamines
    Xiao Qin Xiong
    College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, PR China
    Chem Biodivers 4:43-51. 2007
    ..Preliminary pharmacological tests showed that only 1,4-dioctyl-1,4-diazepan-6-ol (4) had antitumor activity against HeLa cell lines in vitro...
  12. ncbi A phenol quaternary ammonium porphyrin as a potent telomerase inhibitor by selective interaction with quadruplex DNA
    Ping Wang
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072 P R of China
    Chembiochem 7:1155-9. 2006
  13. ncbi Biological studies of photoinducible phenol quaternary ammonium derivatives
    Yang Song
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072, PR China
    Bioorg Med Chem Lett 16:1660-4. 2006
    ..Further tumor cell apoptosis was observed by flow cytometry it indicated that cross-linking agent 5 could significantly induce the late apoptosis of tumor cells...
  14. ncbi DNA hydrolysis promoted by 1,7-dimethyl-1,4,7,10-tetraazacyclododecane
    Shu Hui Wan
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072, PR China
    Bioorg Med Chem Lett 16:2804-6. 2006
    ..pH 7.2 was the optimal condition to cleave DNA in the presence of DMC. Supercoiled DNA hydrolytic cleavage by DMC was supported by the evidence from free radical quenching and T4 ligase ligation...
  15. ncbi Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro
    Christie M Sayes
    Department of Chemistry, Rice University, 1900 Rice Blvd, MS 60, Houston, TX 77005, USA
    Toxicol Lett 161:135-42. 2006
    ..e. the SWNTs in aqueous suspension precipitate out and selectively deposit on the membrane...
  16. pmc Fabrication of porous ultra-short single-walled carbon nanotube nanocomposite scaffolds for bone tissue engineering
    Xinfeng Shi
    Department of Bioengineering, Rice University, MS 142, Houston, TX 77251 1892, USA
    Biomaterials 28:4078-90. 2007
    ..These results indicate that functionalized ultra-short single-walled carbon nanotube nanocomposite scaffolds with tunable porosity and mechanical properties hold great promise for bone tissue engineering applications...
  17. ncbi On-line identification of phenanthroindolizidine alkaloids in a crude extract from Tylophora atrofolliculata by liquid chromatography combined with tandem mass spectrometry
    Lijie Cui
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Rapid Commun Mass Spectrom 18:184-90. 2004
    ..The structures of four of these constituents were subsequently confirmed by nuclear magnetic resonance (NMR) and accurate mass measurements using high-resolution fast-atom bombardment mass spectrometry (FAB-HRMS)...
  18. doi Mice deficient in Neu4 sialidase exhibit abnormal ganglioside catabolism and lysosomal storage
    Volkan Seyrantepe
    Department of Medical Genetics, CHU Sainte Justine, CHUM, University of Montreal, Montreal, Quebec, Canada
    Hum Mol Genet 17:1556-68. 2008
    ..Together, our data suggest that Neu4 is a functional component of the ganglioside-metabolizing system, contributing to the postnatal development of the brain and other vital organs...
  19. ncbi Multi-stage mass spectrometry of furostanol saponins combined with electrospray ionization in positive and negative ion modes
    Yongzhen Liu
    Rapid Commun Mass Spectrom 18:235-8. 2004
  20. ncbi Fluorescence lifetime spectroscopy of a pH-sensitive dye encapsulated in hydrogel beads
    Eddy Kuwana
    The Photon Migration Laboratories, Texas A and M University, College Station, Texas 77843 3573, USA
    Biotechnol Prog 20:1561-6. 2004
    ..When extended to the immobilized fluorophore-enzymatic systems, fluorescence lifetime spectroscopy with multiply scattered light may provide a new ultrasensitive approach for analyte or toxin screening...
  21. ncbi Application of a novel quadrupole linear ion trap mass spectrometer to study the metabolism of 6-aminobutylphthalide in rat brains
    Jin Ping Qiao
    Rapid Commun Mass Spectrom 18:3142-7. 2004
  22. ncbi Structure analyses of dodecylated single-walled carbon nanotubes
    Feng Liang
    Department of Chemistry and Center for Nanoscale Science and Technology, Rice University, Houston, Texas 77005, USA
    J Am Chem Soc 127:13941-8. 2005
    ....
  23. ncbi Structural characterization of steroidal saponins by electrospray ionization and fast-atom bombardment tandem mass spectrometry
    Feng Liang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Rapid Commun Mass Spectrom 16:1168-73. 2002
    ..All of these compounds produced a major product ion with a stable skeleton structure at m/z 255. The results of this paper can assist structural analysis of mixtures of steroidal saponins...