Research Topics
Genomes and Genes
| Yan LiSummaryCountry: China Publications
| Collaborators
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Detail Information
Publications
Multivariate survival and outcome analysis of 154 patients with gastric cancer at a single Chinese institutionHan Lin Wu
Department of Oncology, Wuhan University, Wuhan, China
Asian Pac J Cancer Prev 12:3341-5. 2011..Implementation of standardized radical surgery and reasonable adjuvant therapy could improve survival and prognosis of GC patients...
Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274Jinxuan Hou
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68105, USA
J Transl Med 9:64. 2011..In this study, we investigated the role of c-Met in rhabdomyosarcoma (RMS) using its small molecule inhibitor SU11274, which has been hypothesized to be a potential therapeutic target for RMS...- The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancerWen Qing Hu
Department of Surgery, Heji Hospital Affiliated to Changzhi Medical College, Changzhi 046011, PR China
J Exp Clin Cancer Res 28:144. 2009.... - Coronin-1C is a novel biomarker for hepatocellular carcinoma invasive progression identified by proteomics analysis and clinical validationLong Wu
Department of Oncology, Zhongnan Hospital of Wuhan University and Hubei Key Laboratory of Tumor Biological Behaviors, Wuchang District, 430071 Wuhan, PR China
J Exp Clin Cancer Res 29:17. 2010..To better search for potential markers for hepatocellular carcinoma (HCC) invasion and metastasis, proteomic approach was applied to identify potential metastasis biomarkers associated with HCC... 
[Increased coronin-1C expression is related to hepatocellular carcinoma invasion and metastasis]Long Wu
Department of Oncology, Zhongnan Hospital of Wuhan University and Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan 430071, China
Zhonghua Gan Zang Bing Za Zhi 18:516-9. 2010..To search for hepatocellular carcinoma (HCC) invasion related biomarkers using the cell membrane proteomics approaches, and to validate the markers using experimental and clinical specimens...- Quantum dot-based quantitative immunofluorescence detection and spectrum analysis of epidermal growth factor receptor in breast cancer tissue arraysXue Qin Yang
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory on Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan, People s Republic of China
Int J Nanomedicine 6:2265-73. 2011..The present study was undertaken to investigate the prognostic value of EGFR in breast cancer using quantum dot-based quantitative spectral analysis... - Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from gastric cancer: final results of a phase III randomized clinical trialXiao jun Yang
Department of Oncology, Hubei Cancer Clinical Study Center and Hubei Key Laboratory of Tumor Biological Behaviors, Zhongnan Hospital of Wuhan University, Wuhan, China
Ann Surg Oncol 18:1575-81. 2011..This randomized phase III study was to evaluate the efficacy and safety of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) for the treatment of peritoneal carcinomatosis (PC) from gastric cancer... - Quantum dots-based double-color imaging of HER2 positive breast cancer invasionXiu li Liu
Department of Oncology, Zhongnan Hospital of Wuhan University, No 169 Donghu Road, Wuchang District, Wuhan 430071, PR China
Biochem Biophys Res Commun 409:577-82. 2011..Moreover, HER2 (3+) BC cells also show direct invasion into the blood vessels. This novel imaging method provides direct observable evidence to support the theory that the HER2 expression level is directly related to BC invasion... - Value of tumor markers in diagnosing and monitoring colorectal cancer and strategies for further improvement: analysis of 130 casesChuang Chen
Department of Oncology, Zhongnan Hospital Cancer Center, Wuhan University, Wuhan, Hubei, 430071, PR China
Ai Zheng 26:1221-6. 2007..Measurement of blood tumor markers is the most widely used and convenient method for the diagnosis of colorectal cancer(CRC). This study was to evaluate the diagnostic value of a biochip diagnostic system C12 in the diagnosis of CRC... - Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival of gastric cancer with peritoneal carcinomatosis: evidence from an experimental studyLi Tang
Department of Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, P R China
J Transl Med 9:53. 2011..Results from experimental animal model study could help provide reliable information. This study was to investigate the safety and efficacy of CRS + HIPEC to treat gastric cancer with PC in a rabbit model... - Prevalence and genetic diversity of adeno-associated viruses in bats from ChinaYan Li
State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences CAS, Wuhan, PR China
J Gen Virol 91:2601-9. 2010..3%. Co-presence of multiple distinctive genotypes of bat AAV within an individual sample was also observed. These results demonstrated that diverse AAVs might be widely distributed in bat populations... - NDRG2 inhibits hepatocellular carcinoma adhesion, migration and invasion by regulating CD24 expressionJin Zheng
State Key Discipline of Cell Biology, Department of Oncology, Xijing Hospital, The Fourth Military Medical University, Xi an, 710032, China
BMC Cancer 11:251:1-9. 2011..Understanding the molecular mechanisms underlying HCC metastasis is extremely urgent. The role of CD24 and NDRG2 (N-myc downstream-regulated gene 2), a candidate tumor suppressor gene, has not yet been explored in HCC... - Carbohydrate antigen 242 highly consists with carbohydrate antigen 19-9 in diagnosis and prognosis of colorectal cancer: study on 185 casesXue Qin Yang
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory on Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, No 169 Donghu Road, 430071 Wuhan, China
Med Oncol 29:1030-6. 2012..Both CA19-9 and CA242 had strong consistencies in diagnosis and prognosis for predicting 5-year RFS. CA242 demonstrated superior value to CA19-9 in CRC... - Patterns of cancer invasion revealed by QDs-based quantitative multiplexed imaging of tumor microenvironmentChun Wei Peng
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, No 169 Donghu Road, Wuchang District, Wuhan 430071, PR China
Biomaterials 32:2907-17. 2011..This quantum dots based multiplexed technology could help gain new insight into the complex process of tumor invasion, and formulate new anti-cancer strategies... - Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival in selected patients with peritoneal carcinomatosis from abdominal and pelvic malignancies: results of 21 casesXiao jun Yang
Department of Oncology, Zhongnan Hospital, Cancer Center of Wuhan University, Hubei Cancer Clinical Study Center, Wuchang District, China
Ann Surg Oncol 16:345-51. 2009..5 months). Eleven patients died, three survived with tumor, and seven survived free of tumor. CRS + HIPEC was well tolerated in our selected patients with PC, some of whom had improved survival... - Correlation of TWIST2 up-regulation and epithelial-mesenchymal transition during tumorigenesis and progression of cervical carcinomaYan Li
Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China
Gynecol Oncol 124:112-8. 2012..This study investigated the clinic-pathological significance of twist homolog 2 (TWIST2), a basic helix-loop-helix transcription factor, and correlated TWIST2 and E-cadherin expression in cervical cancer... - Serum CYFRA 21-1 level reflects hepatocellular carcinoma metastasis: study in nude mice model and clinical patientsYan Li
Department of Oncology, Zhongnan Hospital of Wuhan University and Cancer Center of Wuhan University, No 169 Donghu Road, Wuhan, 430071, China
J Cancer Res Clin Oncol 132:515-20. 2006..2%, 13/24) than in CYFRA 21-1 normal cases (21.4%, 18/84) (x2=9.776, P < 0.005). These results suggest that CK19 may play an important role in HCC metastasis... - Synergistic gastric cancer inhibition by chemogenetherapy with recombinant human adenovirus p53 and epirubicin: an in vitro and in vivo studyYi shan Xie
Department of Oncology, Renmin Hospital of Wuhan University, Wuhan 430060, PR China
Oncol Rep 24:1613-20. 2010..No animal death was observed, although 2 nude mice in rAd-p53 group developed liver toxicity and 1 nude mouse in EPI group developed cardiac toxicity. rAd-p53 and EPI have synergistic tumor inhibition effect on gastric cancer cells... - Quantum dots-based molecular classification of breast cancer by quantitative spectroanalysis of hormone receptors and HER2Chuang Chen
Department of Oncology, Zhongnan Hospital of Wuhan University, Wuchang District, Wuhan 430071, PR China
Biomaterials 32:7592-9. 2011.... - Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy to treat gastric cancer with ascites and/or peritoneal carcinomatosis: Results from a Chinese centerXiao jun Yang
Department of Oncology, Zhongnan Hospital Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuchang District, Wuhan, Hubei Province, China
J Surg Oncol 101:457-64. 2010..This work was to evaluate cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) for advanced gastric cancer (GC)... - Cathepsin B cleavable novel prodrug Ac-Phe-Lys-PABC-ADM enhances efficacy at reduced toxicity in treating gastric cancer peritoneal carcinomatosis: an experimental studyLi Hua Shao
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan, China
Cancer 118:2986-96. 2012..The authors examined the antitumor effect and toxicities of Ac-Phe-Lys-PABC-ADM against gastric cancer peritoneal carcinomatosis... - The biocompatibility of quantum dot probes used for the targeted imaging of hepatocellular carcinoma metastasisLiang Dong Chen
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors, No 169 Donghu Road, Wuchang District, Wuhan 430071, China
Biomaterials 29:4170-6. 2008..The results in vitro and in vivo indicate that our QD-based probes have good stability, specificity and biocompatibility for ultrasensitive fluorescence imaging of molecular targets in our liver cancer model system... - Evaluation of the bioconjugation efficiency of different quantum dots as probes for immunostaining tumor-marker proteinsHao Xu
Key Laboratory of Analytical Chemistry for Biology and Medicine Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, PR China
Appl Spectrosc 64:847-52. 2010..The results demonstrate that it is possible to maintain uniform bioconjugation efficiencies with different QD bioconjugation processes in order to obtain accurate and reliable results in biomedical analysis and cancer diagnosis... - Down-regulation of alphav integrin by retroviral delivery of small interfering RNA reduces multicellular resistance of HT29Jian Ming He
Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, PR China
Cancer Lett 284:182-8. 2009..Since force, including adhesion, can activate alphav integrin, cell-cell contact may contribute to activation of alphav integrin, through which increasing phosphorylated p65 and decreasing phosphorylated JNK2 takes part in MCR... - Preoperative serum carbohydrate antigen 242 is a useful predictive and prognostic marker in colorectal cancerXue Qin Yang
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory on Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan, China
Hepatogastroenterology 58:377-82. 2011..Tumor markers (TM) play an important role in the management of colorectal cancer (CRC). This study evaluates the predictive and prognostic value of preoperative serum carbohydrate antigen 242 (CA242) in CRC... - Restoration of the expression of transports associated with antigen processing in human malignant melanoma increases tumor-specific immunityJuan Tao
Department of Dermatology, Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
J Invest Dermatol 128:1991-6. 2008.... - Hadamard transform spectral microscopy for single cell imaging using organic and quantum dot fluorescent probesHao Xu
College of Chemistry and Molecular Science, Wuhan University, Wuhan, 430072, PR China
Analyst 134:504-11. 2009..The preliminary biomedical applications indicate the great potential of the Hadamard imaging system as a useful tool in biomedicine... - Screening the gastric cancer related tumor markers from multi-tumor markers protein chip with kappa coefficient and cost-effectiveness analysisJin Xuan Hou
Department of Oncology, Zhongnan Hospital, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan, China
Hepatogastroenterology 58:632-6. 2011.... - Quantum-dots based simultaneous detection of multiple biomarkers of tumor stromal features to predict clinical outcomes in gastric cancerChun Wei Peng
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, No 169 Donghu Road, Wuchang District, Wuhan 430071, PR China
Biomaterials 33:5742-52. 2012.... - Application of C12 multi-tumor marker protein chip in the diagnosis of gastrointestinal cancer: results of 329 surgical patients and suggestions for improvementXue Qin Yang
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Cancer Clinical Study Center and Hubei Key Laboratory on Tumor Biological Behaviors, Wuhan, 430071, China
Hepatogastroenterology 56:1388-94. 2009..Serum tumor markers (TMs) are frequently used in the diagnosis of GI cancer. This study was to assess value of C12 multi-tumor marker protein chip diagnostic system developed in China in GI cancer... - High Ki-67 expression is a poor prognostic indicator of 5-year recurrence free survival in patients with invasive breast cancerXue Qin Yang
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory on Tumor Biological Behavior and Hubei Cancer Clinical Study Center, Wuhan, China
Asian Pac J Cancer Prev 12:3101-5. 2011..Despite a clear understanding of the protein's structure and properties, its functional role remains elusive. We conducted the present study to assess the prognostic value of Ki-67 in breast cancer (BC)... - Preoperative serum carcinoembryonic antigen, carbohydrate antigen19-9 and carbohydrate antigen 125 as prognostic factors for recurrence-free survival in colorectal cancerXue Qin Yang
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory on Tumor Biological Behavior and Hubei Cancer Clinical Study Center, Wuhan, China
Asian Pac J Cancer Prev 12:1251-6. 2011.... - The expression of endothelin receptor B in melanoma cells A375 and Sk-mel-1 and the proliferative effects of endothelin 3 on A375 cellsNengxing Lin
Department of Dermatology, Union Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
J Huazhong Univ Sci Technolog Med Sci 27:611-3. 2007..ET3 had stronger ability to enhance the proliferation of A375 cells in vitro in a concentration-dependent manner. It was suggested that ET3/ETR-B might play an important proliferative role in MM... - [In-vivo targeted imaging of hepatocellular carcinoma in nude mice using quantum dot probes]Liang Dong Chen
Zhongnan Hospital of Wuhan University and Cancer Center of Wuhan University, Wuhan 430071, China
Zhonghua Bing Li Xue Za Zhi 36:394-9. 2007..To explore in-vivo targeted imaging techniques for liver cancer detection using quantum dots (QDs) labeled probes in a nude mouse model of human hepatocellular carcinoma... - Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cellsXiaoyuan Xu
Department of Histology and Embryology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Int J Dermatol 48:186-92. 2009..To investigate the effect of a Chinese traditional medicine, gambogic acid (GA), on human malignant melanoma (MM) A375 cells and to study the mechanism of apoptosis induced by GA... - Preoperative serum carbohydrate antigen 125 level is an independent negative prognostic marker for overall survival in colorectal cancerXue Qin Yang
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Cancer Clinical Study Center and Hubei Key Laboratory on Tumor Biological Behaviors, No 169 Donghu Road, 430071, Wuhan, China
Med Oncol 28:789-95. 2011..The simultaneously positive serum CA19-9, CEA, and CA125 was the most dismal predicting factor for OS of patients with CRC. Preoperative serum CA125 status and stage were independent prognostic factors for OS of CRC... - Chitosan nanoparticle as gene therapy vector via gastrointestinal mucosa administration: results of an in vitro and in vivo studyFang Zheng
Department of Oncology, Zhongnan Hospital of Wuhan University and Cancer Center of Wuhan University, No 169 Donghu Road, Wuchang District, Wuhan, 430071, China
Life Sci 80:388-96. 2007..TMCO-60%/pDNA nanoparticles had better in vitro and in vivo transfection activity than the other two, and with minimal toxicity, which made it a desirable non-viral vector for gene therapy via oral administration... - Foxc2 overexpression enhances benefit of endothelial progenitor cells for inhibiting neointimal formation by promoting CXCR4-dependent homingDujuan Li
Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
J Vasc Surg 53:1668-78. 2011..CXCR4 plays a critical role in regulating EPCs homing. Here, we studied the effect of Foxc2 overexpression on CXCR4 expression and the homing capacity of EPCs as well as the EPCs-mediated therapeutic benefit after artery injury... - Establishment and identification of a rabbit model of peritoneal carcinomatosis from gastric cancerLie Jun Mei
Department of Oncology, Zhongnan Hospital of Wuhan University and Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, 430071, China
BMC Cancer 10:124. 2010..This study was to establish a stable rabbit peritoneal carcinomatosis model of gastric cancer using VX2 tumor, and analyze the clinico-pathological features... - Evaluation of tumor markers biochip C12 system in the diagnosis of gastric cancer and the strategies for improvement: analysis of 100 casesChuang Chen
Department of Oncology, Zhongnan Hospital and Cancer Center of Wuhah University, Wuhan, China
Hepatogastroenterology 55:991-7. 2008..A C12 biochip system using 12 tumor markers has been developed in China for serum diagnosis of common cancers. This work is to evaluate this C12 system in the diagnosis of gastric cancer... - Carcinoembryonic antigen level is related to tumor invasion into the serosa of the stomach: study on 166 cases and suggestion for new therapyYan Hua Zhang
Department of Oncology, Zhongnan Hospital of Wuhan University, No 169, Donghu Road, Wuhan 430071, China
Hepatogastroenterology 56:1750-4. 2009..The present study aim is to study the significance of serum tumor markers in predicting tumor progression and clinical outcomes in gastric cancer (GC)... - Metastatic factors for Krukenberg tumor: a clinical study on 102 casesLi Qiu
Department of Oncology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China
Med Oncol 28:1514-9. 2011..Multivariate analysis confirmed that invasion depth was the only significant metastatic factor (Relative Risk: 3.2, P=0.004). Primary carcinomas T stage is the most important predictor of Krukenberg tumor from GI cancer... - [Proteasome inhibitors sensitize ovarian cancer cells to cisplatin]Yan Li
Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Zhonghua Fu Chan Ke Za Zhi 45:445-8. 2010..To explore the sensitivity and the molecular mechanism of cisplatin-resistance ovarian cancer cell line C13 to proteasome inhibitors and the combination with cisplatin... - NDRG2 expression regulates CD24 and metastatic potential of breast cancer cellsJin Zheng
Department of Oncology, Xijing Hospital, China
Asian Pac J Cancer Prev 11:1817-21. 2010..In conclusion, the data from the current study indicated that NDRG2, the product of a tumor suppressor gene, can regulate CD24 expression to decrease the metastatic potential of breast cancer cells... - Postoperative recurrence in gastric cancer: analysis of 59 casesChun Wei Peng
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan City, Hubei Province, China
Hepatogastroenterology 57:663-7. 2010..This study was aimed to find out the relationship of cancer recurrence with major clinico-pathological factors, with special attention focused on time of recurrence... - Study on the inhibitory effect of tyroserleutide on tumor growth and metastasis in nude mice model of human hepatocellular carcinoma metastasisPeng cheng Li
Department of Oncology, Zhongnan Hospital of Wuhan University and Cancer Center of Wuhan University Wuhan, China
Hepatogastroenterology 54:1359-63. 2007..This study was designed to test the effect of tyroserleutide on tumor growth and metastasis in a nude mice model of human hepatocellular carcinoma (HCC) metastasis... - Experimental models of hepatocellular carcinoma: developments and evolutionLong Wu
Department of Oncology, Zhongnan Hospital of Wuhan University and Hubei Key Laboratory of Tumour Biological Behaviors, No 169 Donghu Road, Wuchang District, 430071 Wuhan, China
J Cancer Res Clin Oncol 135:969-81. 2009..Each model has its own advantages and disadvantages. The progress in HCC model construction and studies are summarized in this review... - Transplantation of NIT-1 cells expressing pD-L1 for treatment of streptozotocin-induced diabetesXue Wen
Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Transplantation 86:1596-602. 2008..In this study, we tested the effect of PD-L1-transfected pancreatic beta-cell line established from a transgenic NDD/Lt mouse (NIT) on the alloresponse and streptozotocin-induced diabetes... - Quantum-dot-based immunofluorescent imaging of HER2 and ER provides new insights into breast cancer heterogeneityChuang Chen
Department of Oncology, Zhongnan Hospital of Wuhan University, Wuchang District, Wuhan, People s Republic of China
Nanotechnology 21:095101. 2010..Furthermore, the simultaneous imaging of ER and HER2 might help understand their interactions during the process of evolution of heterogeneous BC... - Assessment of cadmium exposure for neonates in Guiyu, an electronic waste pollution site of ChinaYan Li
Analytical Cytology Laboratory and the Key Immunopathology Laboratory of Guangdong Province, Shantou University Medical College, Shantou 515041, China
Environ Monit Assess 177:343-51. 2011..00% (67/100) of Guiyu neonates as compared with 32.69% (17/52) of controls (p < 0.01). Exposure to e-waste recycling pollutants increased Cd exposure in neonates, which was accompanied by increased placental MT expression... - PKD2 mediates multi-drug resistance in breast cancer cells through modulation of P-glycoprotein expressionJiao Chen
State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, PR China
Cancer Lett 300:48-56. 2011..Therefore, modulation of PKD2 activity represents an attractive therapeutic strategy for improvement of the clinical effectiveness of chemotherapy... - [Construction and expression of eukaryotic expression vector of NS1 protein of influenza A (H1N1)]Wen Shuai Zhang
Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Institute of Pathogenic Microbiology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing 210009, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 27:287-9. 2011..To insert the full-length NS1 gene of influenza A (H1N1) into an eukaryotic expression vector PXJ40-HA, and to evaluate the expression of NS1 gene in transfected 293T cells... - [Genotype distribution of enterovirus group C in Shandong Province, China]Yan Li
Shandong Center for Disease Control and Prevention, Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Jinan 250014, China
Bing Du Xue Bao 26:363-7. 2010..The homologous comparison and phylogenetic analysis showed Shandong strains were distinct from prototype strains in each genotype. This report showed that different genotype HEV-C strains spread widely in Shandong Province... - DHA regulates lipogenesis and lipolysis genes in mice adipose and liverChao Sun
College of Animal Science and Technology, Northwest A and F University, 712100, Yangling, Shaanxi, China
Mol Biol Rep 38:731-7. 2011..In liver lipogenesis genes were decreased, but lipolysis genes were increased by DHA. In conclusion, DHA could reduce body fat mass through regulating lipogenesis and lipolysis genes... - Polybrominated diphenyl ethers in chicken tissues and eggs from an electronic waste recycling area in southeast ChinaXiaofei Qin
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
J Environ Sci (China) 23:133-8. 2011..2 to 22.5 ng/(day x kg body weight (bw)) with a mean value of 13.5 ng/(day x kg bw), which was one order of magnitude higher than the value reported in previous studies for consumption of all foodstuffs... - Simultaneous multi-channel CMW-band and MMW-band UWB monocycle pulse generation using FWM effect in a highly nonlinear photonic crystal fiberFangzheng Zhang
Key Laboratory of Information Photonics and Optical Communications, Ministry of Education in China, Beijing University of Posts and Telecommunications, Beijing, 100086, China
Opt Express 18:15870-5. 2010..Experimental measurements of the generated UWB monocycle pulses at individual wavelength, which comply with the FCC regulations, verify the feasibility and flexibility of proposed scheme for use in practical UWB communication systems... - Assessment of the manganese content of the drinking water source in Yancheng, ChinaJinnan Wang
State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210093, China
J Hazard Mater 182:259-65. 2010..Furthermore, the environmental factors affecting the release of manganese from the sediment were also investigated... - [In situ absorption of self-microemulsifying soft capsule of volatile oil from rhizome of ligusticum chuanxiong in rats' intestine]Qin Cai
Sichuan Kelun Drug Development Co Ltd, Chengdu 610500, China
Yao Xue Xue Bao 44:425-9. 2009..Ka and Papp of SMESC at duodenum were significantly higher than that at the other regions of intestine (P < 0.001)... - Thyroid disruption by technical decabromodiphenyl ether (DE-83R) at low concentrations in Xenopus laevisXiaofei Qin
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
J Environ Sci (China) 22:744-51. 2010..laevis tadpoles was close to PBDEs levels in amphibians as reported in previous studies, our study has raised new concerns for thyroid disruption in amphibians of technical decaBDE at environmentally relevant concentrations... - Recurrent atrial arrhythmia after minimally invasive pulmonary vein isolation for atrial fibrillationYaping Zeng
Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China
Ann Thorac Surg 90:510-5. 2010..Minimally invasive pulmonary vein isolation was developed as a treatment of lone atrial fibrillation. Until recently, electrophysiological studies in patients with recurrent arrhythmias had not been described... - [Rapid analysis of L-carnitine in health food by high performance anion exchange chromatography with pulsed amperometric detector]Xiaoli Zou
West China School of Public Health of Sichuan University, Chengdu 610041, China
Wei Sheng Yan Jiu 40:358-60, 364. 2011..A pulsed amperometric detector-high performance anion chromatography method for the determination of L-carnitine in health food was established... - [Genotype distribution of enterovirus group B isolated in Shandong Province, China]Hai Yan Wang
Shandong Center for Disease Control and Prevention, Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Jinan 250014, China
Bing Du Xue Bao 26:357-62. 2010..Thereby the route and range of transmission of HEV could be determined... - Cocirculation of two transmission lineages of echovirus 6 in jinan, china, as revealed by environmental surveillance and sequence analysisZexin Tao
Shandong Center for Disease Control and Prevention, 16992 Jingshi Road, Jinan 250014, People s Republic of China
Appl Environ Microbiol 77:3786-92. 2011..These findings underscore the value of continuous environmental surveillance and genetic analysis to monitor circulating enteroviruses in the population and give further insight into E6 evolution... - [Preparation of monoclonal antibodies against multiple antigens]Dan dan Peng
Institute of Tropical Medicine, Southern Medical University, Guangzhou 510515, China
Di Yi Jun Yi Da Xue Xue Bao 25:40-3. 2005..To prepare monoclonal antibodies (mAbs) against multiple antigens by single cell fusion... - [Construction of adenovirus expressing siRNA against hTR and its anti-tumor activity in vitro]Yan Li
Sichuan University, Chengdu, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 24:570-3. 2008..To study the effect of the hTR-siRNA adenovirus on hTR mRNA gene silence, telomerase activity inhibition and anti-tumor in vitro... - [Determination of meconium lead level of newborn by graphite furnace atomic absorption spectrometry]Yan Li
Central Laboratory, Shantou University Medical College, Shantou 515031, China
Guang Pu Xue Yu Guang Pu Fen Xi 28:447-9. 2008..To establish a method for the determination of lead in meconium from 144 samples of newborn through nitric acid digestion by means of graphite furnace atomic absorption spectrometry... - [Effects of fractionated low dose Cisplatin on renal functions of patients with gastric carcinoma]Yan Li
Department of Gastroenterology, School of Oncology, Peking University, Beijing, 100036, PR China
Ai Zheng 26:1354-6. 2007..This study was to evaluate the effects of fractionated low dose DDP on renal functions of gastric cancer patients... - [Determination of residual acetone in soybean phospholipids by headspace solid-phase microextraction and gas chromatography]Yan Li
Se Pu 22:663. 2004 - In vitro interactions between tacrolimus and azoles against Candida albicans determined by different methodsShujuan Sun
Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, No 66 Jingshi Road, Jinan 250014, Shandong Province, People s Republic of China
Antimicrob Agents Chemother 52:409-17. 2008..The positive interactions were also confirmed by the time-killing test. Our findings suggest a potential role for combination therapy with calcineurin pathway inhibitors and azoles to augment activity against resistant C. albicans... - [Eye acupuncture for treatment of renal and ureteral colic]Qiang Lin
TCM Section, Rizhao City People s Hospital, Shandong 276826, China
Zhongguo Zhen Jiu 27:663-4. 2007..To observe the therapeutic effect of eye acupuncture on renal and ureteral colic induced by ureterolith... - [Temporal and spatial variation of land degradation in alluvial oasis at northern slope of Tianshan Mountain]Yu Gang Wang
Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China
Ying Yong Sheng Tai Xue Bao 18:1311-5. 2007..The regions of poor land quality had an alleviated degradation, with 65.38% of land area improved, while those of good land quality had an aggravated degradation, with 33.38% of land area degraded... - [The cSNPs analysis in whole extron-wide of PGC-1alpha gene in Chinese population and the domain MEF2C bioinformatics study]Wen sheng Lu
Department of Endocrinology, The People s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, 530021 P R China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 24:409-16. 2007.... - [Treatment of a case of Kawasaki's disease complicated with myocardial infarction]Xi hui Li
Department of Cardiovascular Surgery, Peking University First Hospital, Beijing 100034, China
Beijing Da Xue Xue Bao 39:381-4. 2007..Coronary artery by-pass graft is an effective therapeutic strategy for childhood myocardial ischemia, and attention should be paid to some special considerations... - [The association of MMP-13 polymorphism with susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma]Xiao Juan Zhang
Hebei Cancer Institute, Shijiazhuang 050011, China
Yi Chuan 28:1500-4. 2006..Thus, in the region of Hebei Province where there is a high incidence of GCA and ESCC, the MMP-13 A-77G SNP may not be associated with cancer susceptibility. The A/G genotype may confer protection against GCA for smokers... - [Construction of recombinant Mycobacterium smegmatis expressing ESAT-6 and its effects on macrophages]Yan Li
Laboratory of Infection and Immunity, College of Preclinical and Forensic Medicine, West China Medical Center of Sichuan University, Chengdu 610041, China
Nan Fang Yi Ke Da Xue Xue Bao 26:923-6. 2006..Objective To construct recombinant Mycobacterium smegmatis expressing ESAT-6 of the human pathogen Mycobacterium tuberculosis... - [Comparison of corneal wound healing of photorefractive keratectomy and laser in situ keratomileusis in rabbits]Xiao Hua Ma
Jinan Shierming Ophthalmology Hospital, Jinan 250001, China
Zhonghua Yan Ke Za Zhi 39:140-5. 2003..To compare effects of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) on the cornea and corneal wound healing and to investigate the possible mechanism of corneal haze and myopic regression histopathologically... - [Cloning, expression and identification of catalase of Helicobacter pylori]Yan Li
Department of Tropical Diseases, School of Biotechnology, Southern Medical University, Guangzhou 510515, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 22:440-2, 446. 2006..To construct the recombinant plasmid containing catalase (KatA) of Helicobacter pylori (Hp), analyze its nucleic acid sequence, express it in E. coli and study its antigenicity... - [Expression of KAI1, MRP-1, and FAK proteins in lung cancer detected by high-density tissue microarray]Xin Yun Wang
Department of Pathology, Tianjin Medical University, Tianjin, P R China
Ai Zheng 24:1091-5. 2005..This study was designed to investigate the roles of KAI1, MRP-1, and FAK in tumorigenesis and development of lung cancer, and their values in diagnosis and predicting the prognosis of lung cancer... - Rapid and highly sensitive determination of trace proteins using dibromomethyl carboxyazo-Pb(II) complex as a spectroscopic reagentQin Wei
School of Chemistry and Chemical Engineering, Jinan University, China
Clin Chim Acta 362:79-84. 2005..Searching for a sensitive and rapid method for proteins is an ongoing subject of investigation. We describe the reaction of dibromomethyl carboxyazo-Pb(II) with proteins found in urine... - Molecular cloning and characterization of a novel gene encoding zinc finger protein from Medicago sativa LYuehui Chao
Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, People s Republic of China
Mol Biol Rep 36:2315-21. 2009..Under normal growth conditions, differential expression of MsZFN exhibited that the expression was the highest in leaf and the lowest in root. MsZFN was quickly and transiently induced by NaCl treatment and reached its maximum at 30 min... - [Genotype distribution of enterovirus A species isolated in Shandong Province, China]Ze xin Tao
Shandong Center for Disease Control and Prevention, Jinan 250014, China
Bing Du Xue Bao 25:410-4. 2009..The homologous comparison and phylogenetic analysis showed Shandong strains were distinct with prototype strains in every genotype. This report presents an overview of HEV-A in Shandong Province... - Chelation of GRP78 with lead and its localization changes in the astroglia of rats exposed to leadYing Zhang
Institute of Neurology, China Medical University, Shenyang, 110001, China
J Huazhong Univ Sci Technolog Med Sci 29:492-7. 2009..It is concluded that GRP78 in astroglia could strongly chelate with Pb ions and it might be a target protein of Pb... - Phosphate removal from source separated urine by electrocoagulation using iron plate electrodesXiang Yong Zheng
School of Life and Environmental Science, Wenzhou University, No 276, Xue Yuan Road, Lu cheng District, Wenzhou 325027, China
Water Sci Technol 60:2929-38. 2009..It was also revealed that the hydrolysis of urine prior to electrocoagulation treatment impeded phosphate removal... - Ecotoxicological effects of mixed pollutants resulted from e-wastes recycling and bioaccumulation of polybrominated diphenyl ethers in Chinese loach (Misgurnus anguillicaudatus)Xiaofei Qin
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
J Environ Sci (China) 21:1695-701. 2009..Relatively low concentration of BDE 209 (less than 0.01% of total PBDEs) and high concentration of BDE47 (up to 39.34% of total PBDEs) were detected in loaches... - TRAIL-R1 polymorphisms and cancer susceptibility: an evidence-based meta-analysisBo Chen
Department of Geriatrics, First Affiliated Hospital, Nanjing Medical University, Nanjing, China
Eur J Cancer 45:2598-605. 2009..025). In summary, this meta-analysis suggests that TRAIL-R1 C626G polymorphism is marginally associated with cancer susceptibility, and both TRAIL-R1 A1322G G allele and A683C C allele are associated with increased risk for cancer... - [Clinical analysis of preoperative deep venous thrombosis (DVT) complicated lower extremity close fractures]Zhi Qiang Xu
Department of Orthopaedics, Traditional Chinese Medical Hospital of Foshan, Foshan 528000, Guangdong, China
Zhongguo Gu Shang 23:52-4. 2010..To study the instance of deep venous thrombosis(DVT) complicated by preoperative lower extremity close fracture... - [Microclimatic characteristics of different size gaps in Pinus koraiensis-dominated broadleaved mixed forests]Wen biao Duan
College of Forestry, Northeast Forestry University, Harbin 150040, China
Ying Yong Sheng Tai Xue Bao 19:2561-6. 2008..4 times as much as that in small gaps. During growth season, the maximum wind speed above bare ground, large, medium, and small gaps, and closed forest was 3.34, 2.97, 2.87, 2.41 and 1.84 m x s(-1), respectively... - [Research advances in species diversity of arbuscular mycorrhizal fungi]Run Jin Liu
Institute of Mycorrhizal Biotechnology, Qingdao Agricultural University, Qingdao 266109, Shandong, China
Ying Yong Sheng Tai Xue Bao 20:2301-7. 2009..It was considered that molecular biological techniques would be the main approaches in the future study of AM fungal species diversity... - [Spatiotemporal distribution pattern of soil temperature in forest gap of Pinus koraiensis-dominated broadleaved mixed forest in Xiao Xing'an Mountains]Wen biao Duan
College of Forestry, Northeast Forestry University, Harbin 150040, China
Ying Yong Sheng Tai Xue Bao 20:2357-64. 2009..The mean daily temperature in north-south direction exhibited an unapparent single peak behavior, and the mean monthly temperature except in May presented a single peak variation pattern... - [Identification and genetic characterization of human enterovirus type 73, 75, and 97 strains of specie B isolated in Shandong province]Ze xin Tao
Shandong Center for Disease Control and Prevention, Jinan 250014, China
Bing Du Xue Bao 26:16-9. 2010..Sequence analysis of VP1 gene showed significant variation compared with prototype strains. This study presents the genetic characteristics of HEV 73, 75 and 97 of specie B in Shandong Province, and the first report of HEV97 in China... - [Investigations of influential factors of acute renal injury after coronary artery bypass grafting]Xi hui Li
Department of Cardiac Surgery, Peking University First Hospital, Beijing 100034, China
Beijing Da Xue Xue Bao 41:554-7. 2009..To investigate the incidence, correlate factors and effect on convalescent of acute kidney injury (AKI) after coronary artery bypass grafting (CABG)... - Host range, prevalence, and genetic diversity of adenoviruses in batsYan Li
State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences CAS, Wuhan, Hubei 430071, China
J Virol 84:3889-97. 2010.... - Accumulation of nerve growth factor and its receptors in the uterus and dorsal root ganglia in a mouse model of adenomyosisYan Li
Department of Gynaecology, Obstetrics and Gynaecology Hospital, Fudan University, Shanghai, 200011, PR China
Reprod Biol Endocrinol 9:30. 2011..This study aimed to investigate the expression of NGF and its two receptors in uteri and dorsal root ganglia (DRG) in an adenomyosis mouse model, as well as their relationship with the severity of adenomyosis... - Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significanceChun Wei Peng
Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan, China
J Transl Med 8:101. 2010..This study was to determine the roles of MMP-9, MMP-2, type IV collagen, infiltrating macrophages and tumor microvessels in gastric cancer (GC) invasion and their clinico-pathological significance... - [Study on the relationship between polymorphisms of genes (CYP17, CYP19 and SULT1A1) and susceptibility to breast cancer in Chinese women]Ming Bai Hu
Oncology Department of Zhongnan Hospital, Wuhan University, Wuhan 430071, China
Zhonghua Liu Xing Bing Xue Za Zhi 27:351-5. 2006..To investigate the relationship between polymorphisms of genes (CYP17, CYP19 and SULT1A1) involved in estrogen metabolism and susceptibility to breast cancer in Chinese women... - The quantitative detection of total HER2 load by quantum dots and the identification of a new subtype of breast cancer with different 5-year prognosisChuang Chen
Department of Oncology, Zhongnan Hospital of Wuhan University, No 169 Donghu Road, Wuchang District, Wuhan 430071, PR China
Biomaterials 31:8818-25. 2010..Furthermore, this mode integrating macro- and micro-pathological indicators might help gain new insights into invasive BC biological behaviors... - Up-regulation of CC chemokine ligand 20 and its receptor CCR6 in the lesional skin of early systemic sclerosisJuan Tao
Department of Dermatology, Huazhong University of Science and Technology, Wuhan, China
Eur J Dermatol 21:731-6. 2011..Thus our findings suggest that CCL20 released from cytokine-activated SSDF plays an important role in the induction of SSc by further recruiting more MNCs to the skin... - Quantum dots-based immunofluorescence technology for the quantitative determination of HER2 expression in breast cancerChuang Chen
Department of Oncology, Zhongnan Hospital of Wuhan University, Wuchang District, PR China
Biomaterials 30:2912-8. 2009..Compared to conventional immunohistochemistry techniques, this method provided a superior accurate and sensitive method for the detection of HER2 in clinical breast cancer diagnosis... - [Study on the relationship between serum cytokeratin 19 level in hepatocellular carcinoma patients and the clinico-pathologic characteristics]Yan Li
Department of Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
Zhonghua Gan Zang Bing Za Zhi 12:341-2. 2004..chi-square = 13.300, P < 0.005) CONCLUSION: Some HCC patients do have increased serum CK19 level, which could be related to portal vein tumor emboli, poor tumor differentiation and advanced tumor stages... - Adeno-associated virus-mediated local delivery of LIGHT suppresses tumorigenesis in a murine cervical cancer modelMayinuer Maitituoheti
Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China
J Immunother 34:581-7. 2011..Therefore, AAV-LIGHT therapy might have potential utility for the treatment of CC... - Prauserella salsuginis sp. nov., Prauserella flava sp. nov., Prauserella aidingensis sp. nov. and Prauserella sediminis sp. nov., isolated from a salt lakeYan Li
The Key Laboratory for Microbial Resources of the Ministry of Education, PR China, and Laboratory for Conservation and Utilization of Bio resources, Yunnan Institute of Microbiology, Yunnan University, Kunming, Yunnan 650091, PR China
Int J Syst Evol Microbiol 59:2923-8. 2009..nov. (type strain YIM 90636(T)=CCTCC AA 208053(T)=DSM 45266(T)) and Prauserella sediminis sp. nov. (type strain YIM 90694(T)=CCTCC AA 208054(T)=DSM 45267(T))...