Lin Li

Summary

Country: China

Publications

  1. ncbi request reprint [Effects of Ganoderma lucidum spores on HepG2 cells proliferation and growth cycle]
    Lin Li
    Department of Pharmacology, School of Pharmaceutical Science, Southern Medical University, Guangzhou 510515, China
    Zhong Yao Cai 31:1514-8. 2008
  2. pmc Maleic anhydride-modified chicken ovalbumin as an effective and inexpensive anti-HIV microbicide candidate for prevention of HIV sexual transmission
    Lin Li
    School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China
    Retrovirology 7:37. 2010
  3. ncbi request reprint [Morroniside inhibits H2O2-induced apoptosis in cultured nerve cells]
    Hou Xi Ai
    Department of Pharmacology, Xuan Wu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Zhongguo Zhong Yao Za Zhi 33:2109-12. 2008
  4. doi request reprint Vaginal gel formulation based on theaflavin derivatives as a microbicide to prevent HIV sexual transmission
    Jie Yang
    School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China
    AIDS Res Hum Retroviruses 28:1498-508. 2012
  5. doi request reprint Morroniside protects human neuroblastoma SH-SY5Y cells against hydrogen peroxide-induced cytotoxicity
    Wen Wang
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing, China
    Eur J Pharmacol 613:19-23. 2009
  6. doi request reprint Tetrahydroxystilbene glucoside protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity
    Fang ling Sun
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Eur J Pharmacol 660:283-90. 2011
  7. doi request reprint Tetrahydroxystilbene glucoside antagonizes age-related α-synuclein overexpression in the hippocampus of APP transgenic mouse model of Alzheimer's disease
    Lan Zhang
    Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Beijing, China
    Restor Neurol Neurosci 31:41-52. 2013
  8. ncbi request reprint [Effects of Shenwu capsule on learning-memory ability and cholinergic function of brain in AD-like rat model induced by chronic infusion of sodium azide by minipump]
    Lan Zhang
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Zhongguo Zhong Yao Za Zhi 38:1300-5. 2013
  9. ncbi request reprint [Effects of icariin on beta-amyloid and neurotrophic factors in brain of mitochondrial deficiency model rats]
    Ru Yi Zhang
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Zhongguo Zhong Yao Za Zhi 38:1285-9. 2013
  10. pmc Polyanionic candidate microbicides accelerate the formation of semen-derived amyloid fibrils to enhance HIV-1 infection
    Suiyi Tan
    School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China
    PLoS ONE 8:e59777. 2013

Collaborators

Detail Information

Publications21

  1. ncbi request reprint [Effects of Ganoderma lucidum spores on HepG2 cells proliferation and growth cycle]
    Lin Li
    Department of Pharmacology, School of Pharmaceutical Science, Southern Medical University, Guangzhou 510515, China
    Zhong Yao Cai 31:1514-8. 2008
    ..To observe the effects of Ganoderma lucidum Spores (GLS) on proliferation and growth cycle in the human hepatoma cell line (HepG2 cells), and study its possible mechanism of activities...
  2. pmc Maleic anhydride-modified chicken ovalbumin as an effective and inexpensive anti-HIV microbicide candidate for prevention of HIV sexual transmission
    Lin Li
    School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China
    Retrovirology 7:37. 2010
    ..Here we sought to replace bovine protein with an animal protein of non-bovine origin and substitute HP with another anhydride for the development of anti-HIV microbicide for preventing HIV sexual transmission...
  3. ncbi request reprint [Morroniside inhibits H2O2-induced apoptosis in cultured nerve cells]
    Hou Xi Ai
    Department of Pharmacology, Xuan Wu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Zhongguo Zhong Yao Za Zhi 33:2109-12. 2008
    ..To investigate the effects of morroniside on H2O2-induced apoptosis in nerve cells...
  4. doi request reprint Vaginal gel formulation based on theaflavin derivatives as a microbicide to prevent HIV sexual transmission
    Jie Yang
    School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China
    AIDS Res Hum Retroviruses 28:1498-508. 2012
    ....
  5. doi request reprint Morroniside protects human neuroblastoma SH-SY5Y cells against hydrogen peroxide-induced cytotoxicity
    Wen Wang
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing, China
    Eur J Pharmacol 613:19-23. 2009
    ..These results suggest that morroniside has protective effects against oxidative stress-induced neurotoxic processes...
  6. doi request reprint Tetrahydroxystilbene glucoside protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity
    Fang ling Sun
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Eur J Pharmacol 660:283-90. 2011
    ....
  7. doi request reprint Tetrahydroxystilbene glucoside antagonizes age-related α-synuclein overexpression in the hippocampus of APP transgenic mouse model of Alzheimer's disease
    Lan Zhang
    Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Beijing, China
    Restor Neurol Neurosci 31:41-52. 2013
    ....
  8. ncbi request reprint [Effects of Shenwu capsule on learning-memory ability and cholinergic function of brain in AD-like rat model induced by chronic infusion of sodium azide by minipump]
    Lan Zhang
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Zhongguo Zhong Yao Za Zhi 38:1300-5. 2013
    ..Shenwu capsule indicate effectiveness in AD-like mitochondrial deficiency model rats, so it would be applied in the treatment of AD...
  9. ncbi request reprint [Effects of icariin on beta-amyloid and neurotrophic factors in brain of mitochondrial deficiency model rats]
    Ru Yi Zhang
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Zhongguo Zhong Yao Za Zhi 38:1285-9. 2013
    ..The results suggested that ICA may have beneficial prospect for the treatment of Alzheimer's disease...
  10. pmc Polyanionic candidate microbicides accelerate the formation of semen-derived amyloid fibrils to enhance HIV-1 infection
    Suiyi Tan
    School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China
    PLoS ONE 8:e59777. 2013
    ....
  11. doi request reprint 3-Hydroxyphthalic anhydride-modified human serum albumin as a microbicide candidate inhibits HIV infection by blocking viral entry
    Lin Li
    School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China
    J Antimicrob Chemother 68:573-6. 2013
    ..But because OVA may cause allergy in some human subjects, here we replaced OVA with human serum albumin (HSA) in designing a new anti-HIV-1 agent, HP-HSA, and then tested its anti-HIV-1 activity and cytotoxicity...
  12. doi request reprint Sodium tanshinone IIA sulfonate protects cardiomyocytes against oxidative stress-mediated apoptosis through inhibiting JNK activation
    Ruifang Yang
    Department of Pharmacology, School of Pharmacy, Second Military Medical University, Shanghai, China
    J Cardiovasc Pharmacol 51:396-401. 2008
    ..Our further mechanistic study revealed that increased JNK phosphorylation stimulated by H2O2 was abolished by STS treatment. In conclusion, inhibition of JNK activation plays a significant role in cardioprotective effects of STS...
  13. ncbi request reprint [Effects of Shenwu capsule and its component tetrahydroxystilbene glucoside on expression of neurotrophic factors in lumbar spinal cord of aged rats]
    Li Zhang
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Zhongguo Zhong Yao Za Zhi 34:1557-61. 2009
    ..To investigate the effects of Shenwu capsule (SW) and its component tetrahydroxystilbene glucoside (TSG) on the expression of neurotrophic factors in lumbar spinal cord of aged rats...
  14. ncbi request reprint [Evaluation of tongue manifestation of blood stasis syndrome and its relationship with blood rheological disorder in a rat model of transient brain ischemia]
    Hai Feng Wei
    Department of Pharmacology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
    Zhong Xi Yi Jie He Xue Bao 6:73-6. 2008
    ..To study the tongue tissue blood oxygen saturation measurement for evaluating tongue manifestation of blood stasis syndrome, and to explore its correlation with blood rheological disorder in a rat model of acute transient brain ischemia...
  15. ncbi request reprint [Koumine-induced apoptosis of human colonic adenocarcinoma cells: the cell biological mechanism]
    De biao Chi
    School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China
    Nan Fang Yi Ke Da Xue Xue Bao 27:994-7. 2007
    ..To investigate the cell biological mechanism of koumine-induced apoptosis of human colonic adenocarcinoma cells...
  16. doi request reprint Effects of Epimedium flavonoids on proliferation and differentiation of neural stem cells in vitro
    Ruiqin Yao
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing, China
    Neurol Res 32:736-42. 2010
    ....
  17. ncbi request reprint [Semen-derived enhancer of viral infection--a key factor in sexual transmission of HIV]
    Jiang Man Duan
    First School of Clinical Medical Sciences, Guangzhou 510515, China
    Bing Du Xue Bao 28:84-8. 2012
    ..The studies on the biological characteristics and mechanisms of SEVI have a big benefit for the prevention and treatment of HIV infection...
  18. doi request reprint A natural theaflavins preparation inhibits HIV-1 infection by targeting the entry step: potential applications for preventing HIV-1 infection
    Jie Yang
    School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China
    Fitoterapia 83:348-55. 2012
    ..It has a potential to be developed as a safe and affordable topical microbicide for preventing sexual transmission of HIV...
  19. ncbi request reprint [Effects of cornel iridoid glycoside on activity of cholinesterases in vitro]
    Si Juan Chu
    Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
    Zhongguo Zhong Yao Za Zhi 38:1331-4. 2013
    ..CIG also inhibited the activity of BuChE of human blood plasma, with the IC50 of 2.9 g . L-1. In conclusion, CIG can inhibit the activity of AChE and BuChE in vitro, which may be one of the mechanisms of CIG to treat AD...
  20. ncbi request reprint [The significance of quantification of MDR1 and WT1 gene expression in acute myeloid leukemia]
    Bing Xu
    Department of Hematology, Nanfang Hospital, The Southern Medical University, Guangzhou 510515, China
    Zhonghua Nei Ke Za Zhi 47:221-4. 2008
    ..To study the quantification of MDR1 and WT1 gene expression in patients with de novo acute myeloid leukemia (AML) and to explore the role of these two genes in clinical drug resistance and their correlation with risk stratification...
  21. ncbi request reprint Morroniside prevents peroxide-induced apoptosis by induction of endogenous glutathione in human neuroblastoma cells
    Wen Wang
    Department of Pharmacology, Xuan Wu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing, 100053, China
    Cell Mol Neurobiol 28:293-305. 2008
    ..4) This study suggested that intracellular GSH appeared to be an important factor in morroniside-mediated cytoprotection against H(2)O(2)-toxicity in SH-SY5Y cells...