Zheng F, Luo Z, Zheng C, Li J, Zeng J, Yang H, et al
. Comparison of the neurotoxicity associated with cobalt nanoparticles and cobalt chloride in Wistar rats. Toxicol Appl Pharmacol. 2019;369:90-99 pubmed publisher
..In addition, NRF2 protects neural cells from damage induced by CoCl2 and CoNPs by activating downstream antioxidant responses. ..
Zheng F, Li H. Evaluation of Nrf2 with Exposure to Nanoparticles. Methods Mol Biol. 2019;1894:229-246 pubmed publisher
Li H, Wu S, Shi N, Lin W, You J, Zhou W. NF-E2-related factor 2 activation in PC12 cells: its protective role in manganese-induced damage. Arch Toxicol. 2011;85:901-10 pubmed publisher
..Taken together, these findings suggest that Nrf2 may play an important role in the protection of PC12 cells against MnCl(2) neurotoxicity. ..
Li H, Wu S, Wang Z, Lin W, Zhang C, Huang B. Neuroprotective effects of tert-butylhydroquinone on paraquat-induced dopaminergic cell degeneration in C57BL/6 mice and in PC12 cells. Arch Toxicol. 2012;86:1729-40 pubmed publisher
Li H, Wu S, Shi N, Lian S, Lin W. Nrf2/HO-1 pathway activation by manganese is associated with reactive oxygen species and ubiquitin-proteasome pathway, not MAPKs signaling. J Appl Toxicol. 2011;31:690-7 pubmed publisher
..These results suggest that Nrf2/HO-1 activation by Mn in PC12 cells is associated with ROS and the ubiquitin-proteasome pathway, not MAPK signaling. ..
Wang L, Yang H, Wang Q, Zhang Q, Wang Z, Zhang Q, et al
. Paraquat and MPTP induce alteration in the expression profile of long noncoding RNAs in the substantia nigra of mice: Role of the transcription factor Nrf2. Toxicol Lett. 2018;291:11-28 pubmed publisher
..Our findings indicate the potential roles of lncRNAs in the development of PD by PQ or MPTP and provide positive insights into future mechanism studies. ..
Chen S, Chen R, Zhang T, Lin S, Chen Z, Zhao B, et al
. Relationship of cardiovascular disease risk factors and noncoding RNAs with hypertension: a case-control study. BMC Cardiovasc Disord. 2018;18:58 pubmed publisher
..Strikingly, NR_034083, NR_104181 and miR-143 may be correlated with the risk for EH development; therefore, epigenetic markers could be used to measure hypertension levels to help elucidate the pathogenesis of EH. ..
Zhang Z, Guo Z, Zhan Y, Li H, Wu S. Role of histone acetylation in activation of nuclear factor erythroid 2-related factor 2/heme oxygenase 1 pathway by manganese chloride. Toxicol Appl Pharmacol. 2017;336:94-100 pubmed publisher
Guo Z, Zhang Z, Wang Q, Zhang J, Wang L, Zhang Q, et al
. Manganese chloride induces histone acetylation changes in neuronal cells: Its role in manganese-induced damage. Neurotoxicology. 2018;65:255-263 pubmed publisher