Gong Hua Li

Summary

Country: China

Publications

  1. pmc CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site annotation
    Gong Hua Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    BMC Bioinformatics 11:439. 2010
  2. pmc Repeated functional convergent effects of NaV1.7 on acid insensitivity in hibernating mammals
    Zhen Liu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China, University of the Chinese Academy of Sciences, Beijing 100039, China, Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China, Centre for Biodiversity and Conservation Biology, Royal Ontario Museum, Toronto, Canada, M5S 2C6
    Proc Biol Sci 281:20132950. 2014
  3. ncbi Inferring therapeutic targets from heterogeneous data: HKDC1 is a novel potential therapeutic target for cancer
    Gong Hua Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences and Kunming Institute of Zoology, Chinese University of Hongkong Joint Research Center for Bio resources and Human Disease Mechanisms, Kunming, Yunnan 650223, China
    Bioinformatics 30:748-52. 2014
  4. pmc MOfinder: a novel algorithm for detecting overlapping modules from protein-protein interaction network
    Qi Yu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
    J Biomed Biotechnol 2012:103702. 2012
  5. doi CDRUG: a web server for predicting anticancer activity of chemical compounds
    Gong Hua Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
    Bioinformatics 28:3334-5. 2012
  6. doi Comparative systems biology between human and animal models based on next-generation sequencing methods
    Yu Qi Zhao
    Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming Yunnan, China
    Dongwuxue Yanjiu 34:E35-41. 2013
  7. doi Hearing aid for vertebrates via multiple episodic adaptive events on prestin genes
    Zhen Liu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 29:2187-98. 2012

Collaborators

Detail Information

Publications7

  1. pmc CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site annotation
    Gong Hua Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    BMC Bioinformatics 11:439. 2010
    ..This algorithm has been evaluated by building a test set including 164 enzyme families, and also been compared to other methods...
  2. pmc Repeated functional convergent effects of NaV1.7 on acid insensitivity in hibernating mammals
    Zhen Liu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China, University of the Chinese Academy of Sciences, Beijing 100039, China, Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China, Centre for Biodiversity and Conservation Biology, Royal Ontario Museum, Toronto, Canada, M5S 2C6
    Proc Biol Sci 281:20132950. 2014
    ..Our findings not only identify the functional molecules responsible for acid insensitivity in hibernating mammals, but also open new avenues to elucidate the molecular underpinnings of acid insensitivity in mammals. ..
  3. ncbi Inferring therapeutic targets from heterogeneous data: HKDC1 is a novel potential therapeutic target for cancer
    Gong Hua Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences and Kunming Institute of Zoology, Chinese University of Hongkong Joint Research Center for Bio resources and Human Disease Mechanisms, Kunming, Yunnan 650223, China
    Bioinformatics 30:748-52. 2014
    ..Owing to the expansion of cancer-related data, we now have the opportunity to infer therapeutic targets using computational biology methods...
  4. pmc MOfinder: a novel algorithm for detecting overlapping modules from protein-protein interaction network
    Qi Yu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
    J Biomed Biotechnol 2012:103702. 2012
    ..Our study around overlapping modules suggests a new perspective on the analysis of PPI network and improves our understanding of disease...
  5. doi CDRUG: a web server for predicting anticancer activity of chemical compounds
    Gong Hua Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
    Bioinformatics 28:3334-5. 2012
    ..The performance analysis shows that CDRUG has the area under curve of 0.878, indicating that CDRUG is effective to distinguish active and inactive compounds...
  6. doi Comparative systems biology between human and animal models based on next-generation sequencing methods
    Yu Qi Zhao
    Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming Yunnan, China
    Dongwuxue Yanjiu 34:E35-41. 2013
    ..Furthermore, we discuss the applications of RNA-seq and ChIP-seq technologies to comparative systems biology between human and animal models and assess the potential applications for this approach in the future studies...
  7. doi Hearing aid for vertebrates via multiple episodic adaptive events on prestin genes
    Zhen Liu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 29:2187-98. 2012
    ..This study provides new insights into the adaptation and functional diversity of hearing sensitivity in vertebrates by evolutionary and functional analysis of the hearing gene prestin...